Page last updated: 2024-11-05

urethane and Genetic Predisposition

urethane has been researched along with Genetic Predisposition in 24 studies

Research Excerpts

ExcerptRelevanceReference
"Four putative quantitative trait loci (QTLs) that influence susceptibility to the induction of lung adenomas by urethane in an F2 cross between A/J and BALB/cOlaHsd have been mapped."3.70At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice. ( Anna, CH; Devereux, TR; Festing, MF; Gao, F; Lin, L; Malkinson, AM; White, CM; Yang, A; You, M, 1998)
"To determine the locus in the H-2 complex that affects susceptibility to the development of pulmonary adenomas in mice, H-2 congenic and recombinant strains of mice with A/Wy, BALB/c, C3H, and B10 backgrounds were subjected to treatment with urethane."3.67The H-2 class II genes and the susceptibility to the development of pulmonary adenoma in mice. ( Migita, S; Miyashita, N; Moriwaki, K, 1989)
"Hepatic haemangiosarcoma is a deadly malignancy whose aetiology remains poorly understood."1.38ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model. ( Busch, SE; Gurley, KE; Kemp, CJ; Moser, RD, 2012)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.17)18.7374
1990's6 (25.00)18.2507
2000's12 (50.00)29.6817
2010's5 (20.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Champeris Tsaniras, S1
Villiou, M1
Giannou, AD1
Nikou, S1
Petropoulos, M1
Pateras, IS1
Tserou, P1
Karousi, F1
Lalioti, ME1
Gorgoulis, VG1
Patmanidi, AL1
Stathopoulos, GT1
Bravou, V1
Lygerou, Z1
Taraviras, S1
Dassano, A1
Noci, S1
Galbiati, F3
Colombo, F2
Trincucci, G2
Pettinicchio, A3
Dragani, TA7
Manenti, G6
Galvan, A2
Spada, E2
Zolin, A1
Milani, S2
Gonzalez-Neira, A1
Franco, MD1
Cecco, LD1
Ibanez, OM1
Serres, MP1
Zlotek-Zlotkiewicz, E1
Concha, C1
Gurian-West, M1
Daburon, V1
Roberts, JM1
Besson, A1
Busch, SE1
Gurley, KE1
Moser, RD1
Kemp, CJ1
Falvella, FS2
Pascale, RM1
Gariboldi, M2
De Miglio, MR1
Simile, MM1
Feo, F1
Lee, GH2
Nishimori, H1
Sasaki, Y1
Matsushita, H1
Kitagawa, T1
Tokino, T1
Wang, M1
Lemon, WJ1
Liu, G1
Wang, Y1
Iraqi, FA1
Malkinson, AM3
You, M2
Giannì-Barrera, R1
Acevedo, A1
Ozaki, M1
Ozaki, K1
Watanabe, T1
Uwagawa, S1
Okuno, Y1
Shirai, T1
To, MD1
Perez-Losada, J1
Mao, JH1
Hsu, J1
Jacks, T1
Balmain, A1
Binelli, G1
Canzian, F1
De Gregorio, L1
Pierotti, MA1
Karasaki, H1
Obata, M1
Ogawa, K1
Festing, MF1
Lin, L1
Devereux, TR1
Gao, F1
Yang, A1
Anna, CH1
White, CM1
Umemura, T1
Kodama, Y1
Hioki, K1
Inoue, T1
Nomura, T1
Kurokawa, Y1
Timofeeva, OA1
Filipenko, ML1
Kaledin, VI1
Hiai, H1
Abujiang, P1
Nishimura, M1
Sharpless, NE1
Bardeesy, N1
Lee, KH1
Carrasco, D1
Castrillon, DH1
Aguirre, AJ1
Wu, EA1
Horner, JW1
DePinho, RA1
McKenna, IM1
Ramakrishna, G1
Diwan, BA1
Kang, Y1
Shiao, YH1
Wakefield, LM1
Powell, DA1
Anderson, LM1
Jakowlew, SB1
Saran, A1
Zaffaroni, D1
Pazzaglia, S1
Peissel, B1
Spinola, M1
Zanesi, N1
Rebessi, S1
Mancuso, MT1
Covelli, V1
Malkinson, A1
Radcliffe, R1
Bauer, A1
Dwyer-Nield, L1
Kleeberger, S1
Miyashita, N1
Moriwaki, K1
Migita, S1

Reviews

2 reviews available for urethane and Genetic Predisposition

ArticleYear
Polygenic resistance to mouse pulmonary adenomas.
    Experimental lung research, 2000, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chromosomes, Huma

2000
Genetic studies on lung tumor susceptibility and histogenesis in mice.
    Environmental health perspectives, 1991, Volume: 93

    Topics: Alleles; Animals; Butylated Hydroxytoluene; Cell Division; Cocarcinogenesis; Cystadenoma; Genes, ras

1991

Other Studies

22 other studies available for urethane and Genetic Predisposition

ArticleYear
Geminin ablation in vivo enhances tumorigenesis through increased genomic instability.
    The Journal of pathology, 2018, Volume: 246, Issue:2

    Topics: Adenoma; Animals; Ataxia Telangiectasia Mutated Proteins; Azoxymethane; Carcinoma; Colonic Neoplasms

2018
Multigenic nature of the mouse pulmonary adenoma progression 1 locus.
    BMC genomics, 2013, Mar-06, Volume: 14

    Topics: Adenoma; Animals; Chromosome Mapping; Crosses, Genetic; Cyclin-Dependent Kinase Inhibitor p16; Genet

2013
Mouse genome-wide association mapping needs linkage analysis to avoid false-positive Loci.
    PLoS genetics, 2009, Volume: 5, Issue:1

    Topics: Animals; Carcinogens; Chromosome Mapping; Disease Models, Animal; Female; Gene Expression Regulation

2009
Transcriptome of normal lung distinguishes mouse lines with different susceptibility to inflammation and to lung tumorigenesis.
    Cancer letters, 2010, Aug-28, Volume: 294, Issue:2

    Topics: Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Gene Expression; Gene Expr

2010
Cytoplasmic p27 is oncogenic and cooperates with Ras both in vivo and in vitro.
    Oncogene, 2011, Jun-23, Volume: 30, Issue:25

    Topics: Animals; Blotting, Western; Carcinogens; Cyclin-Dependent Kinase Inhibitor p27; Cytoplasm; Fluoresce

2011
ARF suppresses hepatic vascular neoplasia in a carcinogen-exposed murine model.
    The Journal of pathology, 2012, Volume: 227, Issue:3

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Gene D

2012
Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats.
    Carcinogenesis, 2002, Volume: 23, Issue:11

    Topics: Alleles; Animals; Chromosome Mapping; Crosses, Genetic; Enzyme Induction; Genes, Tumor Suppressor; G

2002
Analysis of lung tumorigenesis in chimeric mice indicates the Pulmonary adenoma resistance 2 (Par2) locus to operate in the tumor-initiation stage in a cell-autonomous manner: detection of polymorphisms in the Poli gene as a candidate for Par2.
    Oncogene, 2003, Apr-17, Volume: 22, Issue:15

    Topics: Adenoma; Alleles; Alternative Splicing; Amino Acid Substitution; Animals; Animals, Congenic; Chimera

2003
Fine mapping and identification of candidate pulmonary adenoma susceptibility 1 genes using advanced intercross lines.
    Cancer research, 2003, Jun-15, Volume: 63, Issue:12

    Topics: Adenoma; Animals; Chromosome Mapping; Crosses, Genetic; Gene Expression Profiling; Genes, ras; Genet

2003
Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice.
    Oncogene, 2004, May-27, Volume: 23, Issue:25

    Topics: Adenoma; Alleles; Amino Acid Substitution; Animals; Chromosome Mapping; Crosses, Genetic; Female; Ge

2004
Susceptibilities of p53 knockout and rasH2 transgenic mice to urethane-induced lung carcinogenesis are inherited from their original strains.
    Toxicologic pathology, 2005, Volume: 33, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Body Weight; Disease Models, Animal; Genes, p53; Genes, ras; Genet

2005
A functional switch from lung cancer resistance to susceptibility at the Pas1 locus in Kras2LA2 mice.
    Nature genetics, 2006, Volume: 38, Issue:8

    Topics: Adenoma; Alleles; Animals; Carcinogens; Female; Genetic Predisposition to Disease; Lung Neoplasms; M

2006
Multiple loci affect genetic predisposition to hepatocarcinogenesis in mice.
    Genomics, 1994, Sep-01, Volume: 23, Issue:1

    Topics: Animals; Chromosome Mapping; Crosses, Genetic; Genetic Linkage; Genetic Predisposition to Disease; L

1994
Roles of the Pas1 and Par2 genes in determination of the unique, intermediate susceptibility of BALB/cByJ mice to urethane-induction of lung carcinogenesis: differential effects on tumor multiplicity, size and Kras2 mutations.
    Oncogene, 1997, Oct-09, Volume: 15, Issue:15

    Topics: Animals; Codon; Crosses, Genetic; Female; Genes, ras; Genetic Predisposition to Disease; Lung Neopla

1997
At least four loci and gender are associated with susceptibility to the chemical induction of lung adenomas in A/J x BALB/c mice.
    Genomics, 1998, Oct-15, Volume: 53, Issue:2

    Topics: Adenoma; Animals; Chromosome Mapping; Crosses, Genetic; Female; Genetic Predisposition to Disease; L

1998
Susceptibility to urethane carcinogenesis of transgenic mice carrying a human prototype c-Ha-ras gene (rasH2 mice) and its modification by butylhydroxytoluene.
    Cancer letters, 1999, Oct-18, Volume: 145, Issue:1-2

    Topics: Adenoma; Animals; Butylated Hydroxytoluene; Carcinogens; Female; Genes, ras; Genetic Predisposition

1999
[The study of correlation between the K-ras genotype and murine susceptibility to chemically induced lung neoplasms].
    Genetika, 1999, Volume: 35, Issue:9

    Topics: Animals; Carcinogens; Genes, ras; Genetic Predisposition to Disease; Lung Neoplasms; Mice; Mice, Inb

1999
Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis.
    Nature, 2001, Sep-06, Volume: 413, Issue:6851

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplast

2001
Heterozygous inactivation of TGF-beta1 increases the susceptibility to chemically induced mouse lung tumorigenesis independently of mutational activation of K-ras.
    Toxicology letters, 2001, Sep-15, Volume: 123, Issue:2-3

    Topics: Adenoma; Animals; Carcinogenicity Tests; Carcinogens; Carcinoma; Crosses, Genetic; DNA Mutational An

2001
Inhibition of both skin and lung tumorigenesis by Car-R mouse-derived cancer modifier loci.
    International journal of cancer, 2002, Feb-10, Volume: 97, Issue:5

    Topics: Alleles; Animals; Animals, Outbred Strains; Carcinogenicity Tests; Carcinogens; Female; Genetic Pred

2002
Quantitative trait loci that regulate susceptibility to both butylated hydroxytoluene-induced pulmonary inflammation and lung tumor promotion in CXB recombinant inbred mice.
    Chest, 2002, Volume: 121, Issue:3 Suppl

    Topics: Animals; Butylated Hydroxytoluene; Carcinogens; Chromosome Mapping; Genetic Predisposition to Diseas

2002
The H-2 class II genes and the susceptibility to the development of pulmonary adenoma in mice.
    Immunogenetics, 1989, Volume: 29, Issue:1

    Topics: Adenoma; Animals; Genes, MHC Class I; Genetic Predisposition to Disease; Haplotypes; Lung Neoplasms;

1989