Page last updated: 2024-11-05

urethane and Experimental Hepatoma

urethane has been researched along with Experimental Hepatoma in 19 studies

Research Excerpts

ExcerptRelevanceReference
"The genotoxic carcinogen vinyl carbamate was dosed to C57Bl/10J strain mice for 35 weeks, and the study terminated after week 59."1.28Hepatocarcinogenic effect of vinyl carbamate in the C57Bl/10J strain mouse. ( Marsden, AM; Orton, TC; Willets, JM; Wright, JA, 1991)
"The development of hepatic enzyme-altered foci (ATPase, GGTase) was investigated after dosing vinyl acetate (200 and 400 mg/kg per day, orally) to newborn rats for 3 weeks, with or without subsequent promotion by phenobarbital."1.27Vinyl acetate, a structural analog of vinyl carbamate, fails to induce enzyme-altered foci in rat liver. ( Bolt, HM; Laib, RJ, 1986)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19907 (36.84)18.7374
1990's10 (52.63)18.2507
2000's2 (10.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Falvella, FS3
Pascale, RM1
Gariboldi, M3
Manenti, G4
De Miglio, MR1
Simile, MM1
Dragani, TA5
Feo, F1
HESTON, WE1
VLAHAKIS, G1
DERINGER, MK1
Bull, RJ1
Sasser, LB1
Lei, XC1
Miller, JA5
Miller, EC3
Yun, TK1
Yun, YS1
Han, IW1
Sozzi, G1
Della Porta, G3
Dahl, GA1
Watson, MA1
Devereux, TR1
Malarkey, DE1
Anderson, MW1
Maronpot, RR1
Binelli, G1
Canzian, F1
De Gregorio, L1
Pierotti, MA2
Kim, SG2
Surh, YJ2
Sohn, Y2
Yoo, JK1
Lee, JW1
Liem, A2
Park, KK1
Lee, JM1
Kim, ND1
Mohr, U1
Dasenbrock, C1
Tillmann, T1
Kohler, M1
Kamino, K1
Hagemann, G1
Morawietz, G1
Campo, E1
Cazorla, M1
Fernandez, P1
Hernandez, L1
Cardesa, A1
Tomatis, L1
Wright, JA1
Marsden, AM1
Willets, JM1
Orton, TC1
Leithauser, MT1
Stewart, BC1
Colombo, BM1
Stoewsand, GS1
Anderson, JL1
Munson, L1
Laib, RJ1
Bolt, HM1
Faktor, VM1
Uryvaeva, IV1

Reviews

1 review available for urethane and Experimental Hepatoma

ArticleYear
The metabolic activation and nucleic acid adducts of naturally-occurring carcinogens: recent results with ethyl carbamate and the spice flavors safrole and estragole.
    British journal of cancer, 1983, Volume: 48, Issue:1

    Topics: Adenine; Allylbenzene Derivatives; Animals; Anisoles; Biotransformation; Carcinogens, Environmental;

1983

Other Studies

18 other studies available for urethane and Experimental Hepatoma

ArticleYear
Stearoyl-CoA desaturase 1 (Scd1) gene overexpression is associated with genetic predisposition to hepatocarcinogenesis in mice and rats.
    Carcinogenesis, 2002, Volume: 23, Issue:11

    Topics: Alleles; Animals; Chromosome Mapping; Crosses, Genetic; Enzyme Induction; Genes, Tumor Suppressor; G

2002
High incidence of spontaneous hepatomas and the increase of this incidence with urethan in C3H, C3Hf, and C3He male mice.
    Journal of the National Cancer Institute, 1960, Volume: 24

    Topics: Animals; Carcinoma, Hepatocellular; Incidence; Liver Neoplasms; Liver Neoplasms, Experimental; Male;

1960
Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice.
    Toxicology, 2004, Jul-01, Volume: 199, Issue:2-3

    Topics: Administration, Oral; Animals; Carbon Tetrachloride; Carcinogens; Dichloroacetic Acid; Dose-Response

2004
Anticarcinogenic effect of long-term oral administration of red ginseng on newborn mice exposed to various chemical carcinogens.
    Cancer detection and prevention, 1983, Volume: 6, Issue:6

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Aflatoxin B1; Aflatoxins; Animals; Animals, Newborn; Carc

1983
Spontaneous and urethan-induced tumor incidence in B6C3F1 versus B6CF1 mice.
    Tumori, 1984, Dec-31, Volume: 70, Issue:6

    Topics: Animals; Disease Models, Animal; Female; Hybridization, Genetic; Liver Neoplasms, Experimental; Lung

1984
Comparative carcinogenicities and mutagenicities of vinyl carbamate, ethyl carbamate, and ethyl N-hydroxycarbamate.
    Cancer research, 1980, Volume: 40, Issue:4

    Topics: Adenoma; Animals; Caffeine; Carbamates; Ducks; Ear Neoplasms; Female; Hydroxamic Acids; In Vitro Tec

1980
H-ras oncogene mutation spectra in B6C3F1 and C57BL/6 mouse liver tumors provide evidence for TCDD promotion of spontaneous and vinyl carbamate-initiated liver cells.
    Carcinogenesis, 1995, Volume: 16, Issue:8

    Topics: Animals; Base Sequence; Female; Gene Expression Regulation, Neoplastic; Genes, ras; Liver Neoplasms,

1995
Multiple loci affect genetic predisposition to hepatocarcinogenesis in mice.
    Genomics, 1994, Sep-01, Volume: 23, Issue:1

    Topics: Animals; Chromosome Mapping; Crosses, Genetic; Genetic Linkage; Genetic Predisposition to Disease; L

1994
Inhibition of vinyl carbamate-induced hepatotoxicity, mutagenicity, and tumorigenicity by isopropyl-2-(1,3-dithietane-2-ylidene)-2-[N-(4-methylthiazol-2- yl)carbamoyl]acetate (YH439).
    Carcinogenesis, 1998, Volume: 19, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cytochrome P-450 CYP2E1; Down-Regulation; Female; Liv

1998
Chemopreventive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide.
    Carcinogenesis, 1998, Volume: 19, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Carcinogens; Enzyme Inhibitors; Female; Liver Neoplasms, Experimen

1998
Possible carcinogenic effects of X-rays in a transgenerational study with CBA mice.
    Carcinogenesis, 1999, Volume: 20, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cocarcinogenesis; Female; Genes, ras; Hematologic Neo

1999
Hepatocarcinogenic effect of vinyl carbamate in the C57Bl/10J strain mouse.
    Toxicologic pathology, 1991, Volume: 19, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Female; Gene Expression Regulation, Neoplastic; Liver; Liver Neo

1991
1,N6-ethenoadenosine formation, mutagenicity and murine tumor induction as indicators of the generation of an electrophilic epoxide metabolite of the closely related carcinogens ethyl carbamate (urethane) and vinyl carbamate.
    Carcinogenesis, 1990, Volume: 11, Issue:3

    Topics: Adenosine; Animals; Ditiocarb; Epoxy Compounds; Ethers, Cyclic; Female; Liver Neoplasms, Experimenta

1990
Quantitative analysis of genetic susceptibility to liver and lung carcinogenesis in mice.
    Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 1

    Topics: Age Factors; Animals; Disease Susceptibility; Female; Liver Neoplasms, Experimental; Lung Neoplasms;

1991
Incidence of mutations at codon 61 of the Ha-ras gene in liver tumors of mice genetically susceptible and resistant to hepatocarcinogenesis.
    Oncogene, 1991, Volume: 6, Issue:2

    Topics: Animals; Base Sequence; Codon; Diethylnitrosamine; Female; Genes, ras; Liver Neoplasms, Experimental

1991
Inhibition by wine of tumorigenesis induced by ethyl carbamate (urethane) in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1991, Volume: 29, Issue:5

    Topics: Adenoma; Administration, Oral; Animals; Dose-Response Relationship, Drug; Ethanol; Liver Neoplasms,

1991
Vinyl acetate, a structural analog of vinyl carbamate, fails to induce enzyme-altered foci in rat liver.
    Carcinogenesis, 1986, Volume: 7, Issue:5

    Topics: Adenosine Triphosphatases; Animals; gamma-Glutamyltransferase; Liver; Liver Neoplasms, Experimental;

1986
[Analysis of the DNA content of urethane-induced liver tumors in mice].
    Tsitologiia, 1986, Volume: 28, Issue:6

    Topics: Animals; Carbon Tetrachloride Poisoning; DNA, Neoplasm; Hepatectomy; Liver Neoplasms, Experimental;

1986