urethane has been researched along with Disease Exacerbation in 15 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " The current study explored whether mitochondrial dysfunction correlated with urethane-induced lung carcinogenesis in BALB/c and C57BL/6 mice that were given single- or multi-dose intraperitoneal injections of urethane." | 7.79 | The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis. ( Du, G; Li, H; Li, J; Lin, H; Liu, W; Liu, Y; Sun, T; Wang, Y; Zhang, Y; Zhao, B, 2013) |
| " Additionally, in vitro administration of E2 and G1 increased the number of tumor nodules, tumor grade, and tumor index in a urethane-induced adenocarcinoma model." | 3.81 | G protein-coupled estrogen receptor (GPER) mediates NSCLC progression induced by 17β-estradiol (E2) and selective agonist G1. ( Fan, S; Jiang, Z; Liao, Y; Liu, C; Tang, H; Wang, J; Xiong, J; Zhou, B; Zhou, S; Zou, M, 2015) |
| " The current study explored whether mitochondrial dysfunction correlated with urethane-induced lung carcinogenesis in BALB/c and C57BL/6 mice that were given single- or multi-dose intraperitoneal injections of urethane." | 3.79 | The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis. ( Du, G; Li, H; Li, J; Lin, H; Liu, W; Liu, Y; Sun, T; Wang, Y; Zhang, Y; Zhao, B, 2013) |
| "In the A/J strain of mice, urethane (ethyl carbamate) induces lung hyperplasia, adenoma, and adenocarcinoma in a time-dependent manner." | 3.69 | Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. ( Chen, A; Horio, Y; Malkinson, AM; Rice, P; Roth, JA; Schrump, DS, 1996) |
| "Lung cancer is one of the most incident neoplasms in the world, representing the main cause of mortality for cancer." | 1.38 | The influence of physical activity in the progression of experimental lung cancer in mice. ( Cal, RN; Cordeiro, JA; Cury, PM; dos Santos, CH; Nagamine, KK; Neiva, CM; Paceli, RB, 2012) |
| "Bexarotene (Targretin), is a synthetic high-affinity RXR receptor agonist with limited affinity for RAR receptors." | 1.33 | Prevention of lung cancer progression by bexarotene in mouse models. ( Jia, D; Lubet, RA; Wang, D; Wang, Y; Yao, R; You, M; Zhang, Z, 2006) |
| "There was a higher risk of aneuploidy in the 6-months-of-air-pollution-exposure group (relative risk: 1." | 1.31 | Urban levels of air pollution modifies the progression of urethane-induced lung tumours in mice. ( Capelozzi, VL; Conceição, GM; Cury, PM; Lichtenfels, AJ; Reymão, MS; Saldiva, PH, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 2 (13.33) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Q | 1 |
| Zhang, T | 1 |
| Chang, X | 1 |
| Wang, K | 1 |
| Lee, MH | 1 |
| Ma, WY | 1 |
| Liu, K | 1 |
| Dong, Z | 1 |
| Zhang, HJ | 1 |
| Chang, WJ | 1 |
| Jia, CY | 1 |
| Qiao, L | 1 |
| Zhou, J | 1 |
| Chen, Q | 1 |
| Zheng, XW | 1 |
| Zhang, JH | 1 |
| Li, HC | 1 |
| Yang, ZY | 1 |
| Liu, ZH | 1 |
| Liu, GC | 1 |
| Ji, SP | 1 |
| Lu, F | 1 |
| Sato, A | 1 |
| Yamada, N | 1 |
| Ogawa, Y | 1 |
| Ikegami, M | 1 |
| Fanjul-Fernández, M | 1 |
| Folgueras, AR | 1 |
| Fueyo, A | 1 |
| Balbín, M | 1 |
| Suárez, MF | 1 |
| Fernández-García, MS | 1 |
| Shapiro, SD | 1 |
| Freije, JMP | 1 |
| López-Otín, C | 1 |
| Du, G | 1 |
| Sun, T | 1 |
| Zhang, Y | 1 |
| Lin, H | 1 |
| Li, J | 1 |
| Liu, W | 1 |
| Wang, Y | 3 |
| Zhao, B | 1 |
| Li, H | 1 |
| Liu, Y | 1 |
| Westcott, PM | 1 |
| Halliwill, KD | 1 |
| To, MD | 1 |
| Rashid, M | 1 |
| Rust, AG | 1 |
| Keane, TM | 1 |
| Delrosario, R | 1 |
| Jen, KY | 1 |
| Gurley, KE | 1 |
| Kemp, CJ | 1 |
| Fredlund, E | 1 |
| Quigley, DA | 1 |
| Adams, DJ | 1 |
| Balmain, A | 1 |
| Hashizume, O | 1 |
| Yamanashi, H | 1 |
| Taketo, MM | 1 |
| Nakada, K | 1 |
| Hayashi, J | 1 |
| Liu, C | 1 |
| Liao, Y | 1 |
| Fan, S | 1 |
| Tang, H | 1 |
| Jiang, Z | 1 |
| Zhou, B | 1 |
| Xiong, J | 1 |
| Zhou, S | 1 |
| Zou, M | 1 |
| Wang, J | 1 |
| Paceli, RB | 1 |
| Cal, RN | 1 |
| dos Santos, CH | 1 |
| Cordeiro, JA | 1 |
| Neiva, CM | 1 |
| Nagamine, KK | 1 |
| Cury, PM | 2 |
| Gonçalves, RV | 1 |
| Novaes, RD | 1 |
| Zhang, Z | 2 |
| Lubet, RA | 2 |
| You, M | 2 |
| Yao, R | 1 |
| Jia, D | 1 |
| Wang, D | 1 |
| Horio, Y | 1 |
| Chen, A | 1 |
| Rice, P | 1 |
| Roth, JA | 1 |
| Malkinson, AM | 1 |
| Schrump, DS | 1 |
| Cazorla, M | 1 |
| Hernández, L | 1 |
| Fernández, PL | 1 |
| Fabra, A | 1 |
| Peinado, MA | 1 |
| Dasenbrock, C | 1 |
| Tillmann, T | 1 |
| Kamino, K | 1 |
| Campo, E | 1 |
| Kohler, M | 1 |
| Morawieltz, G | 1 |
| Cardesa, A | 1 |
| Tomatis, L | 1 |
| Mohr, U | 1 |
| Lichtenfels, AJ | 1 |
| Reymão, MS | 1 |
| Conceição, GM | 1 |
| Capelozzi, VL | 1 |
| Saldiva, PH | 1 |
15 other studies available for urethane and Disease Exacerbation
| Article | Year |
|---|---|
Targeting Opsin4/Melanopsin with a Novel Small Molecule Suppresses PKC/RAF/MEK/ERK Signaling and Inhibits Lung Adenocarcinoma Progression.
Topics: A549 Cells; Adenocarcinoma of Lung; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell | 2020 |
Destrin Contributes to Lung Adenocarcinoma Progression by Activating Wnt/β-Catenin Signaling Pathway.
Topics: A549 Cells; Adenocarcinoma of Lung; Animals; beta Catenin; Cell Line, Tumor; Cell Movement; Cell Pro | 2020 |
CCAAT/enhancer-binding protein-α suppresses lung tumor development in mice through the p38α MAP kinase pathway.
Topics: Animals; CCAAT-Enhancer-Binding Protein-alpha; Cell Death; Cell Proliferation; Disease Models, Anima | 2013 |
Matrix metalloproteinase Mmp-1a is dispensable for normal growth and fertility in mice and promotes lung cancer progression by modulating inflammatory responses.
Topics: Animals; Carcinoma; Cell Proliferation; Disease Progression; Gene Expression Regulation, Enzymologic | 2013 |
The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis.
Topics: Animals; Carcinogenesis; Disease Progression; Disease Susceptibility; DNA, Mitochondrial; Electron T | 2013 |
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.
Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplasti | 2015 |
A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNA.
Topics: Adenoma; AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Nuc | 2015 |
G protein-coupled estrogen receptor (GPER) mediates NSCLC progression induced by 17β-estradiol (E2) and selective agonist G1.
Topics: Adenocarcinoma; Aged; Animals; Apoptosis; Blotting, Western; Carcinogens; Carcinoma, Non-Small-Cell | 2015 |
The influence of physical activity in the progression of experimental lung cancer in mice.
Topics: Animals; Carcinogens; Disease Models, Animal; Disease Progression; Hyperplasia; Lung Neoplasms; Male | 2012 |
The influence of physical activity in the progression of experimental lung cancer in mice.
Topics: Adaptation, Physiological; Animals; Carcinogens; Disease Progression; Lung; Lung Neoplasms; Mice; Ne | 2012 |
A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
Topics: Adenocarcinoma; Animals; Cocarcinogenesis; Disease Models, Animal; Disease Progression; Genes, ras; | 2006 |
Prevention of lung cancer progression by bexarotene in mouse models.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Bexarotene; Carcinogens; Carcinoma, Non-S | 2006 |
Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice.
Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Carcinogens; Disease Progression; Exons; Genes, p53 | 1996 |
Ki-ras gene mutations and absence of p53 gene mutations in spontaneous and urethane-induced early lung lesions in CBA/J mice.
Topics: Adenoma; Animals; Carcinoma; Cell Transformation, Neoplastic; Codon; Disease Progression; DNA, Neopl | 1998 |
Urban levels of air pollution modifies the progression of urethane-induced lung tumours in mice.
Topics: Adenoma; Air Pollutants; Air Pollution; Aneuploidy; Animals; Animals, Newborn; Brazil; Carcinogens; | 2000 |