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urethane and Cocarcinogenesis

urethane has been researched along with Cocarcinogenesis in 32 studies

Cocarcinogenesis: The combination of two or more different factors in the production of cancer.

Research Excerpts

ExcerptRelevanceReference
" Promotion by mezerein as well as carcinogenesis by repeated treatment with DMBA or MNNG produced papillomas with a high frequency of conversion to squamous cell carcinomas (SCCs)."3.69New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin. ( Hennings, H; Lowry, DT; Mock, B; Potter, M; Yuspa, SH, 1997)
"Mouse skin tumors, benign papillomas, and squamous cell carcinomas (SCCs) were initiated by a single topical application of urethane followed by repeated promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA)."3.67Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane. ( Bonham, K; Bowden, GT; Cress, AE; Embry, T; Gibson, D; Jaffe, DR; Roberts, RA, 1989)
"The papillomas are heterogeneous in their potential for progression to carcinomas, a property apparently induced at the time of initiation."1.28Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin. ( Hennings, H, 1991)
" This hypothesis was tested directly by chronic administration of BHT, BHT-BuOH, and two other metabolites, 2,6-di-tert-butyl-4-hydroxymethyl phenol and 2,6-di-tert-butyl-1,4-benzoquinone to MA/MyJ mice following a single injection of urethane."1.28A metabolite of butylated hydroxytoluene with potent tumor-promoting activity in mouse lung. ( Fernandez, CA; Malkinson, AM; Schullek, KM; Thompson, JA, 1989)
"N-Nitrosocimetidine (NCM) is a nitrosation product of cimetidine, a commonly-prescribed pharmaceutical agent."1.27N-nitrosocimetidine as a modifier of chemically-initiated tumors in mice. ( Anderson, LM; Giner-Sorolla, A; Hagiwara, A; Kovatch, RM; Rehm, S; Rice, JM; Riggs, CW, 1988)
"The first group showed squamous cell carcinomas in the nasal cavity (4 out of 10 mice), trachea (4 out of 10 mice) and lung (2 out of 10 mice)."1.27Effects of minute amounts of cigarette smoke with or without nebulized N-nitroso-N-methylurethane on the respiratory tract of mice. ( Ide, G; Iwasaki, I; Takahashi, A, 1985)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199021 (65.63)18.7374
1990's9 (28.13)18.2507
2000's2 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
PERISSINOTTO, B1
Wang, Y1
Zhang, Z1
Lubet, RA1
You, M1
Harper, BL1
Morris, DL1
Chieco-Bianchi, L1
Aldovini, A2
Ronchese, F2
De Rossi, A1
Majone, F1
Montaldi, A1
Levis, AG1
Witschi, HR2
Doherty, DG1
Morse, CC1
Witschi, HP1
Armuth, V1
Berenblum, I1
Theiss, JC2
Shimkin, MB2
Arnold, LJ1
Moĭzhess, TG1
Trukhanova, LS1
Vasil'ev, IuM1
Hennings, H4
Lowry, DT1
Yuspa, SH2
Mock, B1
Potter, M1
Cattanach, BM1
Papworth, D1
Patrick, G1
Goodhead, DT1
Hacker, T1
Cobb, L1
Whitehill, E1
Mohr, U1
Dasenbrock, C1
Tillmann, T1
Kohler, M1
Kamino, K1
Hagemann, G1
Morawietz, G1
Campo, E1
Cazorla, M1
Fernandez, P1
Hernandez, L1
Cardesa, A1
Tomatis, L1
Koujitani, T1
Yasuhara, K1
Tamura, T1
Onodera, H1
Takagi, H1
Takizawa, T1
Hirose, M1
Hayashi, Y1
Mitsumori, K1
Sula, J1
Anisimov, VN1
Malkinson, AM3
Iversen, OH1
Shores, R1
Balaschak, M1
Heinrich, U1
Pott, F1
Rittinghausen, S1
Bonham, K1
Embry, T1
Gibson, D1
Jaffe, DR1
Roberts, RA1
Cress, AE1
Bowden, GT2
Thompson, JA1
Schullek, KM1
Fernandez, CA1
Ward, JM1
Rehm, S2
Devor, D1
Wenk, ML1
Anderson, LM1
Hagiwara, A1
Giner-Sorolla, A1
Kovatch, RM1
Riggs, CW1
Rice, JM1
Blakley, BR1
Last, JA1
Warren, DL1
Pecquet-Goad, E1
Witschi, H1
Takahashi, A1
Iwasaki, I1
Ide, G1
Thaete, LG1
Barnhart, KM1

Reviews

2 reviews available for urethane and Cocarcinogenesis

ArticleYear
Experimental data concerning the question of the synergic action of the influenza virus and of some chemical carcinogens in the pathogenesis of lung cancer.
    Neoplasma, 1979, Volume: 26, Issue:1

    Topics: Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Humans; Influenza, Human; Lung Neoplasms

1979
Genetic studies on lung tumor susceptibility and histogenesis in mice.
    Environmental health perspectives, 1991, Volume: 93

    Topics: Alleles; Animals; Butylated Hydroxytoluene; Cell Division; Cocarcinogenesis; Cystadenoma; Genes, ras

1991

Other Studies

30 other studies available for urethane and Cocarcinogenesis

ArticleYear
[Attempted cocarcinogenesis by combined urethane and turpentine in mice].
    Rivista di anatomia patologica e di oncologia, 1953, Volume: 7, Issue:2

    Topics: Animals; Cocarcinogenesis; Lung Neoplasms; Mice; Neoplasms, Experimental; Turpentine; Urethane

1953
A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
    Oncogene, 2006, Feb-23, Volume: 25, Issue:8

    Topics: Adenocarcinoma; Animals; Cocarcinogenesis; Disease Models, Animal; Disease Progression; Genes, ras;

2006
Implications of multiple mechanisms of carcinogenesis for short-term testing.
    Teratogenesis, carcinogenesis, and mutagenesis, 1984, Volume: 4, Issue:6

    Topics: Asbestos; Carcinogens; Chemical Phenomena; Chemistry; Cocarcinogenesis; Diethylstilbestrol; DNA; Enz

1984
Short- and long-term studies on chemical carcinogenesis in BALB/Mo mice.
    Toxicologic pathology, 1984, Volume: 12, Issue:4

    Topics: Adenoma; Animals; Animals, Newborn; Bromodeoxyuridine; Cocarcinogenesis; Deoxyadenosines; Female; Lu

1984
Butylated hydroxyanisole and lung tumor development in A/J mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:5

    Topics: Animals; Anisoles; Benzo(a)pyrene; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Cell Division

1984
Enhancement of lung tumor formation in mice by dietary butylated hydroxytoluene: dose-time relationships and cell kinetics.
    Journal of the National Cancer Institute, 1983, Volume: 71, Issue:4

    Topics: Animals; Autoradiography; Body Weight; Butylated Hydroxytoluene; Cell Division; Cocarcinogenesis; Di

1983
Different susceptibility of BALB/Mo and BALB/c mice to cytogenetic damage induced by urethan.
    Tumori, 1983, Oct-31, Volume: 69, Issue:5

    Topics: Animals; Body Weight; Chromosomes; Cocarcinogenesis; Mice; Mice, Inbred BALB C; Moloney murine leuke

1983
Promotion of lung tumors in mice.
    Environmental health perspectives, 1983, Volume: 50

    Topics: Animals; Butylated Hydroxytoluene; Cell Division; Cocarcinogenesis; Dose-Response Relationship, Drug

1983
Further exploration of stages in carcinogenesis.
    Carcinogenesis; a comprehensive survey, 1982, Volume: 7

    Topics: Animals; Caffeine; Cocarcinogenesis; Female; Isoxazoles; Mice; Mice, Inbred ICR; Neoplasms, Experime

1982
Effect of the plant growth regulator, 2-chloroethylphosphonic acid, on spontaneous and chemically-induced lung tumorigenesis in strain A mice.
    Food and cosmetics toxicology, 1980, Volume: 18, Issue:2

    Topics: Adenoma; Animals; Cell Division; Cocarcinogenesis; DNA, Neoplasm; Female; Lung Neoplasms; Male; Mice

1980
Effect of commercial saccharin preparations on urethan-induced lung tumorigenesis in strain A mice.
    Cancer research, 1980, Volume: 40, Issue:11

    Topics: Adenoma; Animals; Cocarcinogenesis; Lung Neoplasms; Male; Mice; Mice, Inbred A; Neoplasms, Experimen

1980
[Use of a foreign body as a promotor for detecting the ability of various chemical substances to initiate carcinogenesis in connective tissue].
    Doklady Akademii nauk, 1994, Volume: 337, Issue:1

    Topics: 1,2-Dimethylhydrazine; Animals; Carcinogens; Cocarcinogenesis; Diethylnitrosamine; Dimethylhydrazine

1994
New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin.
    Molecular carcinogenesis, 1997, Volume: 20, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis;

1997
Investigation of lung tumour induction in C3H/HeH mice, with and without tumour promotion with urethane, following paternal X-irradiation.
    Mutation research, 1998, Jul-17, Volume: 403, Issue:1-2

    Topics: Animals; Carcinogens; Child; Cocarcinogenesis; Dose-Response Relationship, Radiation; Fathers; Femal

1998
Possible carcinogenic effects of X-rays in a transgenerational study with CBA mice.
    Carcinogenesis, 1999, Volume: 20, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cocarcinogenesis; Female; Genes, ras; Hematologic Neo

1999
Lack of modifying effects of eugenol on development of lung proliferative lesions induced by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.
    The Journal of toxicological sciences, 2001, Volume: 26, Issue:3

    Topics: Adenoma; Animals; Bronchi; Carcinogenicity Tests; Carcinogens; Carcinoma; Cocarcinogenesis; Disease

2001
Two-step carcinogenesis induced by neonatal exposure to 5-bromo-2'- deoxyuridine and subsequent administration of urethan in BALB/c mice.
    Cancer letters, 1992, May-30, Volume: 64, Issue:1

    Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Body Weight; Bromodeoxyuridine; Cocarcinogenesis

1992
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
    Basic life sciences, 1991, Volume: 57

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Ce

1991
Urethan (ethyl carbamate) is an effective promoter of 7,12-dimethylbenz[a]anthracene-induced carcinogenesis in mouse skin two-stage experiments.
    Carcinogenesis, 1991, Volume: 12, Issue:5

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenoma; Animals; Cocarcinogenesis; Female; Lung Neoplasms; Male;

1991
Sensitivity of subpopulations of mouse skin papillomas to malignant conversion by urethane or 4-nitroquinoline N-oxide.
    Cancer research, 1990, Feb-01, Volume: 50, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Mi

1990
Comparison of chronic inhalation effects in rodents after long-term exposure to either coal oven flue gas mixed with pyrolized pitch or diesel engine exhaust.
    Developments in toxicology and environmental science, 1986, Volume: 13

    Topics: Administration, Inhalation; Animals; Body Burden; Coal; Cocarcinogenesis; Cricetinae; Female; Lung;

1986
Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane.
    Molecular carcinogenesis, 1989, Volume: 2, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Codon; DNA Pro

1989
A metabolite of butylated hydroxytoluene with potent tumor-promoting activity in mouse lung.
    Carcinogenesis, 1989, Volume: 10, Issue:4

    Topics: Animals; Biotransformation; Butylated Hydroxytoluene; Carcinogens; Cocarcinogenesis; Lung; Lung Neop

1989
Differential carcinogenic effects of intraperitoneal initiation with 7,12-dimethylbenz(a)anthracene or urethane and topical promotion with 12-O-tetradecanoylphorbol-13-acetate in skin and internal tissues of female SENCAR and BALB/c mice.
    Environmental health perspectives, 1986, Volume: 68

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Topical; Animals; Cocarcinogenesis; Female; Inject

1986
N-nitrosocimetidine as a modifier of chemically-initiated tumors in mice.
    Cancer letters, 1988, Volume: 42, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Cimetidine; Cocarcinogenesis; Lung Neoplasms; Mice; Neopl

1988
Alterations in urethan-induced adenoma formation in mice exposed to selenium and nickel.
    Journal of applied toxicology : JAT, 1987, Volume: 7, Issue:6

    Topics: Adenoma; Animals; Body Weight; Cocarcinogenesis; Drinking; Female; Lung Neoplasms; Mice; Nickel; Sel

1987
Modification by ozone of lung tumor development in mice.
    Journal of the National Cancer Institute, 1987, Volume: 78, Issue:1

    Topics: Air Pollution; Animals; Cocarcinogenesis; Drug Interactions; Humans; Lung Neoplasms; Male; Mice; Mic

1987
Effects of minute amounts of cigarette smoke with or without nebulized N-nitroso-N-methylurethane on the respiratory tract of mice.
    Japanese journal of cancer research : Gann, 1985, Volume: 76, Issue:5

    Topics: Aerosols; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Epithelium; Hyperplasia; Lung Neoplas

1985
Effects of strain and age on prophylaxis and co-carcinogenesis of urethan-induced mouse lung adenomas by butylated hydroxytoluene.
    Cancer research, 1986, Volume: 46, Issue:4 Pt 1

    Topics: Adenoma; Age Factors; Animals; Butylated Hydroxytoluene; Cocarcinogenesis; Lung Neoplasms; Mice; Mic

1986
Cisplatin as an initiating agent in two-stage mouse skin carcinogenesis.
    Cancer letters, 1985, Volume: 29, Issue:1

    Topics: Animals; Carcinogens; Cisplatin; Cocarcinogenesis; Female; Injections, Intraperitoneal; Mice; Papill

1985