Page last updated: 2024-11-05

urethane and Cleft Palate, Isolated

urethane has been researched along with Cleft Palate, Isolated in 6 studies

Research Excerpts

ExcerptRelevanceReference
"To determine whether the administration of urethane also decreases the associated cleft palate in CL/Fr mice, pregnant CL/Fr mice (30% of their offspring have spontaneous cleft lip with associated cleft palate [CL/P]) were treated with various doses of urethane on different days of pregnancy."7.67Effect of maternal urethane administration on the manifestation of cleft lip and palate in CL/Fr mice. ( Kameyama, Y; Nakane, K, 1986)
"Activation of the maternal immune system in mice decreased cleft palate caused by the chemical teratogen, urethane."3.72Maternal immune stimulation reduces both placental morphologic damage and down-regulated placental growth-factor and cell cycle gene expression caused by urethane: are these events related to reduced teratogenesis? ( Gogal, RM; Holladay, SD; Sharov, AA; Sharova, LV; Smith, BJ; Sura, P, 2003)
"Teratogenic chemicals (2,3,7, 8-tetrachlorodibenzo-p-dioxin [TCDD], ethyl carbamate [urethane], methylnitrosourea [MNU], or valproic acid [VA]) were given to pregnant mice to induce cleft palate (TCDD, urethane), digital defects (urethane, MNU), or exencephaly (VA)."3.70Nonspecific stimulation of the maternal immune system. I. Effects On teratogen-induced fetal malformations. ( Blaylock, BL; Gogal, RM; Holladay, SD; Sharova, L; Smith, BJ; Ward, DL, 2000)
"Ethyl carbamate (urethane) was given to pregnant ICR mice on day 10 of gestation to induce cleft palate."3.70Nonspecific stimulation of the maternal immune system. II. Effects on gene expression in the fetus. ( Gogal, RM; Holladay, SD; Sharov, AA; Sharova, L; Smith, BJ; Sura, P; Ward, DL, 2000)
"To determine whether the administration of urethane also decreases the associated cleft palate in CL/Fr mice, pregnant CL/Fr mice (30% of their offspring have spontaneous cleft lip with associated cleft palate [CL/P]) were treated with various doses of urethane on different days of pregnancy."3.67Effect of maternal urethane administration on the manifestation of cleft lip and palate in CL/Fr mice. ( Kameyama, Y; Nakane, K, 1986)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sharova, LV1
Sharov, AA2
Sura, P2
Gogal, RM3
Smith, BJ3
Holladay, SD3
Sharova, L2
Ward, DL2
Blaylock, BL1
Gotoh, H1
Nomura, T1
Nakajima, H1
Hasegawa, C1
Sakamoto, Y1
Nakane, K1
Kameyama, Y1
Peters, S1
Strassburg, M1

Other Studies

6 other studies available for urethane and Cleft Palate, Isolated

ArticleYear
Maternal immune stimulation reduces both placental morphologic damage and down-regulated placental growth-factor and cell cycle gene expression caused by urethane: are these events related to reduced teratogenesis?
    International immunopharmacology, 2003, Volume: 3, Issue:7

    Topics: Adjuvants, Immunologic; Animals; Cell Cycle Proteins; Cleft Palate; Cytokines; Down-Regulation; Embr

2003
Nonspecific stimulation of the maternal immune system. I. Effects On teratogen-induced fetal malformations.
    Teratology, 2000, Volume: 62, Issue:6

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Adjuvants, Immunologic; Animals; BCG Vaccine;

2000
Nonspecific stimulation of the maternal immune system. II. Effects on gene expression in the fetus.
    Teratology, 2000, Volume: 62, Issue:6

    Topics: Abnormalities, Drug-Induced; Adjuvants, Immunologic; Animals; Apoptosis; Cell Cycle; Cleft Palate; E

2000
Inhibiting effects of nicotinamide on urethane-induced malformations and tumors in mice.
    Mutation research, 1988, Volume: 199, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Cleft Lip; Cleft Palate; Dose-Response Relationship, Drug; Fem

1988
Effect of maternal urethane administration on the manifestation of cleft lip and palate in CL/Fr mice.
    Journal of craniofacial genetics and developmental biology. Supplement, 1986, Volume: 2

    Topics: Animals; Cleft Lip; Cleft Palate; Female; Fetal Death; Mice; Mice, Inbred Strains; Pregnancy; Terato

1986
[Animal experimental studies on the creation of cleft palate].
    Deutsche zahnarztliche Zeitschrift, 1968, Volume: 23, Issue:3

    Topics: Animals; Cleft Palate; Diet; Immune Sera; Injections, Subcutaneous; Mice; Urethane

1968