Page last updated: 2024-11-05

urethane and Carcinoma, Hepatocellular

urethane has been researched along with Carcinoma, Hepatocellular in 40 studies

Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.

Research Excerpts

ExcerptRelevanceReference
"The genotoxic carcinogen vinyl carbamate was dosed to C57Bl/10J strain mice for 35 weeks, and the study terminated after week 59."1.28Hepatocarcinogenic effect of vinyl carbamate in the C57Bl/10J strain mouse. ( Marsden, AM; Orton, TC; Willets, JM; Wright, JA, 1991)
"Urethane was found to be uniformly distributed in all the major organs of foetal, young and adult ICR/Jcl mice and then to disappear rapidly as measured by the incorporation of urethane-carbonyl-14C, thus permitting the accurate comparison of tumour susceptibility of cells in various organs of mice at different ages."1.26Comparison of tumour susceptibility among various organs of foetal, young and adult ICR/Jcl mice. ( Nomura, T, 1976)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199037 (92.50)18.7374
1990's1 (2.50)18.2507
2000's0 (0.00)29.6817
2010's2 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, H1
Cui, B1
Xu, Y1
Hu, C1
Liu, Y1
Qu, G1
Li, D1
Wu, Y1
Zhang, D1
Quan, S1
Shi, J1
Hashizume, O1
Yamanashi, H1
Taketo, MM1
Nakada, K1
Hayashi, J1
KLEIN, M2
LAW, LW2
PRECERUTTI, A2
CHIECO-BIANCHI, L2
DEBENEDICTIS, G1
TRIDENTE, G2
FIORE-DONATI, L2
TRAININ, N1
LIEBELT, RA2
LIEBELT, AG1
LANE, M2
HESTON, WE1
VLAHAKIS, G1
DERINGER, MK1
Nomura, T4
Wright, JA1
Marsden, AM1
Willets, JM1
Orton, TC1
Adamson, RH1
Shimkin, MB1
De Benedictis, G1
Gullino, PM1
Grantham, FH1
Courtney, AH1
Vesselinovitch, SD6
Mihailovich, N6
Pietra, G1
Della Porta, G1
Hollander, CF1
Bentvelzen, P1
Adenis, L1
Demaille, A1
Driessens, J1
Mirvish, SS1
Stromskaia, TP1
Pogosiants, EE1
Sokova, OI1
Prigozhina, EL1
Liebelt, A1
Calvert, J1
Frei, JV1
Itze, L2
Chernozemski, IN1
Warwick, GP1
Rao, KV1
Kondrat'eva, AF1
Lombardi, L1
Matsuyama, M1
Suzuki, H1
Ito, M1
Yamada, S1
Nagayo, T1
Okamoto, E2
Tomatis, L2
Turusov, V1
Day, N1
Charles, RT1
Breslow, NE1
Day, NE1
Turusov, VS1
Pound, AW1
Lawson, TA1
Tateishi, N1
Kimura, S1
Isa, Y1
Ranadive, DV1
Arjungi, KN1
Bhide, SV1

Reviews

3 reviews available for urethane and Carcinoma, Hepatocellular

ArticleYear
Use of newborn and infant animals in carcinogenicity testing.
    Food and cosmetics toxicology, 1968, Volume: 6, Issue:2

    Topics: Age Factors; Animals; Animals, Newborn; Anthracenes; Carcinogens; Carcinoma, Hepatocellular; Hydroca

1968
The carcinogenic action and metabolism of urethan and N-hydroxyurethan.
    Advances in cancer research, 1968, Volume: 11

    Topics: Adenoma; Animals; Animals, Newborn; Body Fluids; Breast Neoplasms; Carbamates; Carcinogens; Carcinom

1968
[The combined action of ionizing radiation and carcinogens].
    Voprosy onkologii, 1969, Volume: 15, Issue:3

    Topics: Animals; Benz(a)Anthracenes; Bone Neoplasms; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma,

1969

Other Studies

37 other studies available for urethane and Carcinoma, Hepatocellular

ArticleYear
Ethyl carbamate induces cell death through its effects on multiple metabolic pathways.
    Chemico-biological interactions, 2017, Nov-01, Volume: 277

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Death; Hep G2 Cells; Humans; Liver Neoplasms;

2017
A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNA.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Adenoma; AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Nuc

2015
Induction of lymphocyticlasms, hepatomas, and other tumors after oral administration of urethan to infant mice.
    Journal of the National Cancer Institute, 1962, Volume: 29

    Topics: Administration, Oral; Animals; Carcinoma, Hepatocellular; Leukemia; Leukemia, Lymphoid; Liver Neopla

1962
INHIBITION BY URETHAN (ETHYL CARBAMATE) OF VIRUS INDUCTION OF LEUKAEMIA IN C3H MICE.
    Nature, 1963, Nov-16, Volume: 200

    Topics: Adenoma; Animals; Carcinoma, Hepatocellular; Leukemia; Leukemia, Experimental; Liver Neoplasms; Lung

1963
INFLUENCE OF AGE ON SUSCEPTIBILITY TO LIVER CARCINOGENESIS AND SKIN INITIATING ACTION BY URETHANE IN SWISS MICE.
    British journal of cancer, 1963, Volume: 17

    Topics: Aging; Animals; Animals, Newborn; Carcinogenesis; Carcinoma, Hepatocellular; Croton Oil; Female; Hum

1963
TRENDS IN CARCINOGENESIS BY URETHAN ADMINISTRATION TO NEW-BORN MICE OF DIFFERENT STRAINS.
    Nature, 1964, Apr-18, Volume: 202

    Topics: Adenoma; Animals; Animals, Newborn; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Genetics

1964
HORMONAL INFLUENCES ON URETHAN CARCINOGENESIS IN C3H/F MICE.
    Cancer research, 1964, Volume: 24

    Topics: Adrenal Gland Neoplasms; Androgens; Animals; Animals, Newborn; Carcinogenesis; Carcinogens; Carcinom

1964
High incidence of spontaneous hepatomas and the increase of this incidence with urethan in C3H, C3Hf, and C3He male mice.
    Journal of the National Cancer Institute, 1960, Volume: 24

    Topics: Animals; Carcinoma, Hepatocellular; Incidence; Liver Neoplasms; Liver Neoplasms, Experimental; Male;

1960
Comparison of tumour susceptibility among various organs of foetal, young and adult ICR/Jcl mice.
    British journal of cancer, 1976, Volume: 33, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Cell Differentiation; Cell Division; Fe

1976
Hepatocarcinogenic effect of vinyl carbamate in the C57Bl/10J strain mouse.
    Toxicologic pathology, 1991, Volume: 19, Issue:3

    Topics: Animals; Carcinoma, Hepatocellular; Female; Gene Expression Regulation, Neoplastic; Liver; Liver Neo

1991
Induction of hepatocellular carcinoma in nonhuman primates by chemical carcinogens.
    Cancer detection and prevention, 1989, Volume: 14, Issue:2

    Topics: 2-Acetylaminofluorene; Aflatoxins; Animals; Carcinogens, Environmental; Carcinoma, Hepatocellular; C

1989
Biological tests of carcinogenic activity.
    Archives of environmental health, 1968, Volume: 16, Issue:4

    Topics: Animals; Azo Compounds; Biological Assay; Carcinogens; Carcinoma, Hepatocellular; Carcinoma, Papilla

1968
Influence of age on induction with urethan of hepatomas and other tumors in infant mice.
    Journal of the National Cancer Institute, 1966, Volume: 36, Issue:6

    Topics: Aging; Animals; Carcinoma, Hepatocellular; Liver Neoplasms; Mice; Neoplasms, Experimental; Urethane

1966
[Effect of the age factor on the development of malignant lymphomas and hepatomas in Swiss mice treated with urethane (ethyl carbamate)].
    Bollettino della Societa italiana di biologia sperimentale, 1964, Jun-15, Volume: 40, Issue:11

    Topics: Aging; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Female; Liver Neoplasms; Lymphoma; Male

1964
Utilization of oxygen by transplanted tumors in vivo.
    Cancer research, 1967, Volume: 27, Issue:6

    Topics: Anemia; Anesthesia, General; Animals; Blood Flow Velocity; Carbon Dioxide; Carcinoma 256, Walker; Ca

1967
The neonatal and infant age periods as biologic factors which modify multicarcinogenesis by urethan.
    Cancer research, 1967, Volume: 27, Issue:8

    Topics: Age Factors; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Eye Neoplasms; Female; Liver Neop

1967
The effect of gonadectomy on the development of hepatomas induced by urethan.
    Cancer research, 1967, Volume: 27, Issue:10

    Topics: Adenoma; Adrenal Gland Diseases; Animals; Carcinoma, Hepatocellular; Castration; Female; Gonadal Ste

1967
The prenatal exposure of mice to urethan and the consequent development of tumors in various tissues.
    Cancer research, 1967, Volume: 27, Issue:12

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Liver Neoplasms; L

1967
The induction of benign and malignant liver tumors by urethan in newborn rats.
    Cancer research, 1968, Volume: 28, Issue:5

    Topics: Adenoma, Bile Duct; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Injections, Intraperitonea

1968
Enhancement of urethan induction of hepatomas in mice by prior partial hepatectomy.
    Journal of the National Cancer Institute, 1968, Volume: 41, Issue:6

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Hepatectomy; Leukemia, Experimental; Liver Neoplasm

1968
[Cancerogenic power of urethane in Sprague rats].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1968, Volume: 162, Issue:2

    Topics: Adenofibroma; Adrenal Gland Neoplasms; Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Hema

1968
[The oncogenic effect of urethane and myeloid chlorleukemia virus on adult mice].
    Voprosy onkologii, 1970, Volume: 16, Issue:2

    Topics: Adenoma; Age Factors; Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Leukemia Virus, Murin

1970
[A new animal for experimental oncologic research--the Dzhungarian hamster].
    Voprosy onkologii, 1970, Volume: 16, Issue:3

    Topics: Animals; Animals, Laboratory; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cel

1970
Effect of partial hepatectomy on tumor incidence in BALB-c mice treated with urethan.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Division; Female; Hepatectomy; Leukemia, Exper

1970
Toxicity, tissue changes, and tumor induction in inbred Swiss mice by methylnitrosamine and -amide compounds.
    Cancer research, 1970, Volume: 30, Issue:1

    Topics: Adenoma; Animals; Animals, Newborn; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Carcinoma, Hep

1970
Comparative studies on the kinetics of the neoplastic competence in mice.
    Cancer research, 1970, Volume: 30, Issue:10

    Topics: Adenoma; Age Factors; Animals; Animals, Newborn; Carcinoma, Hepatocellular; Female; Lacrimal Apparat

1970
Liver regeneration and induction of hepatomas in B6AF mice by urethan.
    Cancer research, 1970, Volume: 30, Issue:11

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DNA; Female; Hepatectomy; Liver Neoplasms; Liver Re

1970
Perinatal carcinogenesis by urethan.
    Cancer research, 1971, Volume: 31, Issue:12

    Topics: Adenoma; Age Factors; Animals; Carcinoma, Hepatocellular; Cystadenoma; Female; Gestational Age; Lacr

1971
Ultrastructural study of nucleolar alterations produced by a single carcinogenic dose of urethan in mouse hepatocytes.
    Cancer research, 1972, Volume: 32, Issue:4

    Topics: Animals; Carcinogens; Carcinoma, Hepatocellular; Cell Nucleolus; Female; Liver; Liver Neoplasms; Mal

1972
Strain difference in carcinogenesis by urethan administration to suckling rats.
    Gan, 1972, Volume: 63, Issue:2

    Topics: Adenoma, Islet Cell; Animals; Carcinogens; Carcinoma, Hepatocellular; Cystadenoma; Female; Injection

1972
Transplacental carcinogenesis by urethan in mice: teratogenesis and carcinogenesis in relation to organogenesis.
    Gan, 1972, Volume: 63, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Carcinoma, Hepatocellular; Cystadenoma; Endometrial Hyperplasi

1972
Carcinogenesis by urethan via mother's milk and its enhancement of transplacental carcinogenesis in mice.
    Cancer research, 1973, Volume: 33, Issue:7

    Topics: Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Cystadenoma; Female; Gestational

1973
The effect of long-term exposure to DDT on CF-1 MICE.
    International journal of cancer, 1972, Volume: 10, Issue:3

    Topics: Animals; Body Weight; Carcinoma, Hepatocellular; DDT; Dose-Response Relationship, Drug; Female; Fert

1972
Associations between tumor types in a large-scale carcinogenesis study of CF-1 mice.
    Journal of the National Cancer Institute, 1974, Volume: 52, Issue:1

    Topics: Adenoma; Age Factors; Animals; Bone Neoplasms; Carcinogens; Carcinoma, Hepatocellular; DDT; Female;

1974
Effects of partial hepatectomy on carcinogenicity, metabolism, and binding to DNA of ethyl carbamate.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:2

    Topics: Adenoma; Animals; Carcinogens; Carcinoma, Hepatocellular; Croton Oil; DNA; Female; Hemangioma; Hepat

1974
Tumor induction in the progeny of mice receiving 4-nitroquinoline 1-oxide and N-methyl-N-nitrosourethan during pregnancy or lactation.
    Cancer research, 1974, Volume: 34, Issue:12

    Topics: Abnormalities, Drug-Induced; Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Fetus; Gestati

1974
Infrared spectra of DNA from normal & urethan-treated mice.
    Indian journal of biochemistry & biophysics, 1974, Volume: 11, Issue:2

    Topics: Animals; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Liver; Liver Neoplasms; Male; Mice; Neoplasm

1974