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urethane and Carcinoma, Epidermoid

urethane has been researched along with Carcinoma, Epidermoid in 29 studies

Research Excerpts

ExcerptRelevanceReference
"The number of papillomas that develop in mice initiated with a single exposure to urethane and promoted by repeated applications of 12-O-tetradecanoylphorbol-13-acetate (TPA) is increased greater than 4-fold by pretreating the skin once with TPA 24 hr before administration of urethane."7.68Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion. ( Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH, 1991)
" Promotion by mezerein as well as carcinogenesis by repeated treatment with DMBA or MNNG produced papillomas with a high frequency of conversion to squamous cell carcinomas (SCCs)."3.69New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin. ( Hennings, H; Lowry, DT; Mock, B; Potter, M; Yuspa, SH, 1997)
"The number of papillomas that develop in mice initiated with a single exposure to urethane and promoted by repeated applications of 12-O-tetradecanoylphorbol-13-acetate (TPA) is increased greater than 4-fold by pretreating the skin once with TPA 24 hr before administration of urethane."3.68Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion. ( Greenhalgh, DG; Hennings, H; Robinson, VA; Welty, DJ; Yuspa, SH, 1991)
"Mouse skin tumors, benign papillomas, and squamous cell carcinomas (SCCs) were initiated by a single topical application of urethane followed by repeated promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA)."3.67Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane. ( Bonham, K; Bowden, GT; Cress, AE; Embry, T; Gibson, D; Jaffe, DR; Roberts, RA, 1989)
"When pioglitazone was administered beginning 8 weeks after the first carcinogen treatment when microscopic adenomas already existed, pioglitazone significantly inhibited tumor load (sum of tumor volume per lung in average) by 64% (P < 0."1.36Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice. ( James, M; Lu, Y; Lubet, RA; Szabo, E; Wang, Y; Wen, W; You, M, 2010)
"The papillomas are heterogeneous in their potential for progression to carcinomas, a property apparently induced at the time of initiation."1.28Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin. ( Hennings, H, 1991)
"The first group showed squamous cell carcinomas in the nasal cavity (4 out of 10 mice), trachea (4 out of 10 mice) and lung (2 out of 10 mice)."1.27Effects of minute amounts of cigarette smoke with or without nebulized N-nitroso-N-methylurethane on the respiratory tract of mice. ( Ide, G; Iwasaki, I; Takahashi, A, 1985)
"Most of the tumors induced were invasive squamous carcinomas of the stomach."1.26Carcinogenesis in Sprague-Dawley rats of N-nitroso-N-alkylcarbamate esters. ( Lijinsky, W; Taylor, HW, 1976)
"The study on morphogenesis of squamous cell carcinomas arising from the upper digestive tract indicates that the majority of tumors of the esophagus and forestomach may pass through acanthosis or hyperkeratosis, leukokeratosis, and papilloma, and finally develop into invasive squamous cell carcinoma, but many carcinomas of the oral cavity and pharnyx, especially the tongue, may develop without passing through a papillomatous stage."1.26Tumors of the upper digestive tract of ACI/N rats given N-propyl-N-nitrosourethan in the drinking water. ( Kamiya, S; Maekawa, A; Odashima, S, 1976)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199023 (79.31)18.7374
1990's4 (13.79)18.2507
2000's1 (3.45)29.6817
2010's1 (3.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wang, Y1
James, M1
Wen, W1
Lu, Y1
Szabo, E1
Lubet, RA1
You, M1
SCHOENTAL, R3
MAGEE, PN1
AXELROD, AR1
BERMAN, L1
Van Duuren, BL1
Sivak, A1
Langseth, L1
Hirono, I1
Hosaka, S1
Kuhara, K1
Hennings, H3
Lowry, DT1
Yuspa, SH2
Mock, B1
Potter, M1
Hiai, H1
Abujiang, P1
Nishimura, M1
Yasumoto, T1
Lijinsky, W1
Taylor, HW1
Fujii, M1
Maekawa, A1
Kamiya, S1
Odashima, S1
Nelson, MA1
Futscher, BW1
Kinsella, T1
Wymer, J1
Bowden, GT2
Robinson, VA1
Welty, DJ1
Greenhalgh, DG1
Bonham, K1
Embry, T1
Gibson, D1
Jaffe, DR1
Roberts, RA1
Cress, AE1
Yokota, K1
Hattori, A1
Kunz, HW1
Gill, TJ1
Shinozuka, H1
Takahashi, A1
Iwasaki, I1
Ide, G1
Armstrong, JG1
Napalkov, NP1
Alexandrov, VA1
Pogosiants, EE1
Sokova, OI1
Prigozhina, EL1
Kondrat'eva, AF1
Snyder, C1
Malone, B1
Nettesheim, P1
Snyder, F1
Pound, AW1
Bardos, TJ1
Ambrus, JL1
Ambrus, CM1
Shabad, LM1
Thomas, C1
So, BT1
Herrold, KM1

Reviews

2 reviews available for urethane and Carcinoma, Epidermoid

ArticleYear
Polygenic resistance to mouse pulmonary adenomas.
    Experimental lung research, 2000, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chromosomes, Huma

2000
[The combined action of ionizing radiation and carcinogens].
    Voprosy onkologii, 1969, Volume: 15, Issue:3

    Topics: Animals; Benz(a)Anthracenes; Bone Neoplasms; Carbon Tetrachloride Poisoning; Carcinogens; Carcinoma,

1969

Other Studies

27 other studies available for urethane and Carcinoma, Epidermoid

ArticleYear
Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:11

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Chemopreventi

2010
Induction of squamous carcinoma of the lung and of the stomach and oesophagus by diazomethane and N-methyl-N-nitroso-urethane, respectively.
    British journal of cancer, 1962, Volume: 16

    Topics: Animals; Azo Compounds; Carcinogens; Carcinoma, Squamous Cell; Diazomethane; Esophageal Neoplasms; L

1962
INDUCTION OF TUMOURS OF THE STOMACH IN RATS AND MICE BY N-NITROSO-NALKYLURETHANES.
    Nature, 1963, Jul-13, Volume: 199

    Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Mice; Neoplasms, Experime

1963
EXPERIMENTAL INDUCTION OF SQUAMOUS CARCINOMA OF THE LUNG, OESOPHAGUS AND STOMACH. THE MODE OF THEIR INDUCTION.
    Acta - Unio Internationalis Contra Cancrum, 1963, Volume: 19

    Topics: Animals; Benzopyrenes; Carcinoma; Carcinoma, Squamous Cell; Esophageal Neoplasms; Lung Neoplasms; Mi

1963
Multiple squamous cell carcinoma of the skin associated with chronic lymphatic leukemia; observations on the effect of urethane therapy.
    Archives of dermatology and syphilology, 1949, Volume: 60, Issue:4

    Topics: Carcinoma, Squamous Cell; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Lymphoid; Skin

1949
The tumor-promoting activity of tobacco leaf extract and whole cigarette tar.
    British journal of cancer, 1967, Volume: 21, Issue:2

    Topics: Animals; Benz(a)Anthracenes; Carcinoma, Squamous Cell; Female; Fibrosarcoma; Injections, Intraperito

1967
Enhancement by bracken of induction of tumours of the upper alimentary tract by N-propyl-N-nitrosourethan.
    British journal of cancer, 1982, Volume: 46, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Gastrointestinal Ne

1982
New strains of inbred SENCAR mice with increased susceptibility to induction of papillomas and squamous cell carcinomas in skin.
    Molecular carcinogenesis, 1997, Volume: 20, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Carcinoma, Squamous Cell; Cocarcinogenesis;

1997
Studies on N-butyl-N-nitrosourethan-induced cancers of the esophagus and the forestomach of rats.
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1978, Mar-01, Volume: 47, Issue:2

    Topics: Animals; Bleomycin; Carcinoma, Squamous Cell; Esophageal Neoplasms; Neoplasms, Experimental; Nitroso

1978
Carcinogenesis in Sprague-Dawley rats of N-nitroso-N-alkylcarbamate esters.
    Cancer letters, 1976, Volume: 1, Issue:5

    Topics: Administration, Oral; Administration, Topical; Animals; Carbaryl; Carcinoma, Squamous Cell; Female;

1976
Carcinogenic effect of N-butyl-N-nitrosourethan on CDF1 mice.
    Gan, 1976, Volume: 67, Issue:2

    Topics: Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cell Transformatio

1976
Tumors of the upper digestive tract of ACI/N rats given N-propyl-N-nitrosourethan in the drinking water.
    Gan, 1976, Volume: 67, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; Female; Intestinal Neoplasms; Leukoplakia; Male; Mouth Neoplasms;

1976
Detection of mutant Ha-ras genes in chemically initiated mouse skin epidermis before the development of benign tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 1992, Jul-15, Volume: 89, Issue:14

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Base Sequence; Carcinoma, Squamous Cell; DNA, Ne

1992
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
    Basic life sciences, 1991, Volume: 57

    Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Ce

1991
Activation of the rasHa gene in urethane-initiated papillomas induced by protocols with high and low frequencies of malignant conversion.
    Cancer communications, 1991, Volume: 3, Issue:9

    Topics: 3T3 Cells; Animals; Blotting, Southern; Carcinogens; Carcinoma, Squamous Cell; Cell Transformation,

1991
Activation of the cellular Harvey ras gene in mouse skin tumors initiated with urethane.
    Molecular carcinogenesis, 1989, Volume: 2, Issue:1

    Topics: Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; Codon; DNA Pro

1989
Experimental analysis of the effects of cyclosporine on the induction and growth of epithelial tumors.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 3

    Topics: Adenoma; Administration, Oral; Administration, Topical; Animals; Carcinoma, Squamous Cell; Cell Divi

1989
Effects of minute amounts of cigarette smoke with or without nebulized N-nitroso-N-methylurethane on the respiratory tract of mice.
    Japanese journal of cancer research : Gann, 1985, Volume: 76, Issue:5

    Topics: Aerosols; Animals; Carcinoma, Squamous Cell; Cocarcinogenesis; Epithelium; Hyperplasia; Lung Neoplas

1985
Current problems in the use of the oncolytic drugs.
    Acta geneticae medicae et gemellologiae, 1968, Volume: 17, Issue:1

    Topics: Antineoplastic Agents; Busulfan; Carcinoma, Squamous Cell; Child; Chlorambucil; Choriocarcinoma; Dac

1968
On the effects of blastomogenic substances on the organism during embryogenesis.
    Zeitschrift fur Krebsforschung, 1968, Volume: 71, Issue:1

    Topics: Abnormalities, Drug-Induced; Aniline Compounds; Animals; Benz(a)Anthracenes; Carcinoma; Carcinoma, S

1968
[A new animal for experimental oncologic research--the Dzhungarian hamster].
    Voprosy onkologii, 1970, Volume: 16, Issue:3

    Topics: Animals; Animals, Laboratory; Benz(a)Anthracenes; Carcinoma, Hepatocellular; Carcinoma, Squamous Cel

1970
Urethan-induced pulmonary adenoma as a tool for the study of surfactant biosynthesis.
    Cancer research, 1973, Volume: 33, Issue:10

    Topics: Adenoma; Adenosine Triphosphate; Animals; Calcium; Carbon Radioisotopes; Carcinoma, Squamous Cell; C

1973
Tumour formation in mice by urethane administered with related carbamates.
    British journal of cancer, 1972, Volume: 26, Issue:3

    Topics: Animals; Carbamates; Carcinoma; Carcinoma, Squamous Cell; Croton Oil; Drug Interactions; Esters; Inj

1972
Combination of chemotherapy with dual antagonists and radiotherapy in the treatment of neoplastic disease.
    Journal of surgical oncology, 1971, Volume: 3, Issue:4

    Topics: Alkylating Agents; Antimetabolites; Antineoplastic Agents; Azirines; Carbamates; Carcinoma, Bronchog

1971
Dose-response studies in experimentally induced lung tumours.
    Environmental research, 1971, Volume: 4, Issue:4

    Topics: Adenocarcinoma; Adenoma; Air Pollution; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Carc

1971
[Morphology of N-nitroso-compound induced tumors in the upper digestive tract of rats].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:7

    Topics: Amino Alcohols; Animals; Carcinogens; Carcinoma, Squamous Cell; Esophageal Neoplasms; Esters; Ethyla

1969
Epidermoid carcinomas of esophagus and forestomach induced in Syrian hamsters by N-nitroso-N-methylurethan.
    Journal of the National Cancer Institute, 1966, Volume: 37, Issue:3

    Topics: Animals; Carcinoma, Squamous Cell; Cricetinae; Esophageal Neoplasms; Neoplasm Metastasis; Neoplasms,

1966