Page last updated: 2024-11-05

urethane and Carcinogenesis

urethane has been researched along with Carcinogenesis in 57 studies

Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.

Research Excerpts

ExcerptRelevanceReference
"To analyze whether TGF-β exerts suppressive or oncogenic actions on mammary carcinogenesis, transgenic mice overexpressing a dominant-negative mutant type II TGF-β receptor (TβRII-DNR) driven by the mouse mammary tumor virus (MMTV) promoter were treated with a low dose of urethane, a carcinogen present in fermented food products and alcoholic beverages."7.96Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor. ( Kondo, Y; Morimoto, J; Shibata, E; Shibata, MA, 2020)
"This study suggests a novel function of emodin, whereby it selectively suppresses N2 neutrophils to prevent hypercoagulation and lung carcinogenesis."7.91Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis. ( Du, G; Duan, Y; Li, Z; Lin, H; Lin, Y; Tong, Q; Wang, M; Wang, Y; Yan, G; Zhang, M; Zhang, S; Zhou, L, 2019)
"The carcinogenesis of urethane (ethyl carbamate), a byproduct of fermentation that is consistently found in various food products, was investigated with a combination of kinetic experiments and quantum chemical calculations."7.81Carcinogenesis of urethane: simulation versus experiment. ( Bren, U; Guengerich, FP; Lajovic, A; Nagy, LD, 2015)
" The current study explored whether mitochondrial dysfunction correlated with urethane-induced lung carcinogenesis in BALB/c and C57BL/6 mice that were given single- or multi-dose intraperitoneal injections of urethane."7.79The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis. ( Du, G; Li, H; Li, J; Lin, H; Liu, W; Liu, Y; Sun, T; Wang, Y; Zhang, Y; Zhao, B, 2013)
"Chemical induced carcinogenesis together with genetically engineered mouse models represent important approaches for the study of the complex mechanisms involving genotype and environmental factors in cancer development, including lung cancer."5.62Urethane-induced lung carcinogenesis. ( Del Prete, A; Schioppa, T; Sozio, F; Sozzani, S, 2021)
"Urethane is a recognized genotoxic carcinogen in fermented foods and beverages."5.43Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro. ( Cao, N; Deng, J; Du, G; Duan, Y; Geng, S; Guo, Z; Lin, H; Ma, X; Meng, M; Zheng, Y, 2016)
"Urethane-induced lung carcinogenesis led to more M2 macrophage phenotype and increased abnormal angiogenesis concomitant with the upregulation of LC3-B and the downregulation of p62."5.43The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis. ( Cao, N; Du, GJ; Geng, SN; Guo, ZZ; Han, G; Li, GG; Lin, HH; Ma, XF; Meng, MJ; Zheng, YQ, 2016)
"Our data validate chemical carcinogenesis as a suitable "in vivo" model for further and more detailed studies on the molecular mechanisms of the death response induced by Col V in lung infiltrating adenocarcinoma opening new strategies for treatment."5.43Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model. ( Alveno, RA; Capelozzi, VL; Corrêa, PY; de Morais, J; Fabro, AT; Faustino, CB; Parra, ER; Rangel, MP; Teodoro, WR; Vargas, CM; Velosa, AP, 2016)
"Curcumin has long been recognized as a chemopreventive agent, but poor bioavailability and weak Nrf2 induction have prohibited clinical application."5.42A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response. ( Chapman, E; Chen, J; Jiang, T; Long, M; Ren, DM; Shen, T; Wong, PK; Zhang, DD; Zhou, B, 2015)
" We elucidated the relationship between Nrf2 expression levels and whole exon mutation patterns using an ethyl-carbamate (urethane)-induced lung carcinogenesis model employing Nrf2-deficient and Keap1-kd mice, the latter of which express high levels of Nrf2."4.12Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels. ( Arai, Y; Furukawa, E; Hama, N; Kato, M; Moriguchi, T; Ohe, Y; Satoh, H; Shibata, T; Totoki, Y; Urushidate, T; Yamamoto, M, 2022)
"To analyze whether TGF-β exerts suppressive or oncogenic actions on mammary carcinogenesis, transgenic mice overexpressing a dominant-negative mutant type II TGF-β receptor (TβRII-DNR) driven by the mouse mammary tumor virus (MMTV) promoter were treated with a low dose of urethane, a carcinogen present in fermented food products and alcoholic beverages."3.96Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor. ( Kondo, Y; Morimoto, J; Shibata, E; Shibata, MA, 2020)
"This study suggests a novel function of emodin, whereby it selectively suppresses N2 neutrophils to prevent hypercoagulation and lung carcinogenesis."3.91Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis. ( Du, G; Duan, Y; Li, Z; Lin, H; Lin, Y; Tong, Q; Wang, M; Wang, Y; Yan, G; Zhang, M; Zhang, S; Zhou, L, 2019)
" In conclusion, AKT1E17K induces hyperplasia of mouse lung epithelium in vivo and cooperates with urethane to induce the fully malignant phenotype."3.83AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer. ( Belmonte, S; Camastra, C; Colelli, F; De Marco, C; Fagman, H; Gagliardi, M; Malanga, D; Mignogna, C; Mirante, T; Oliveira, DM; Paciello, O; Papparella, S; Rizzuto, A; Scarfò, M; Viglietto, G, 2016)
" A mouse model of urethane-induced lung adenocarcinoma was used in the study."3.80Fulvestrant-mediated inhibition of estrogen receptor signaling slows lung cancer progression. ( Chen, G; Fu, S; Liao, Y; Liu, Z; Tang, H; Xu, L; Yu, L; Zhang, C; Zhou, S, 2014)
" The current study explored whether mitochondrial dysfunction correlated with urethane-induced lung carcinogenesis in BALB/c and C57BL/6 mice that were given single- or multi-dose intraperitoneal injections of urethane."3.79The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis. ( Du, G; Li, H; Li, J; Lin, H; Liu, W; Liu, Y; Sun, T; Wang, Y; Zhang, Y; Zhao, B, 2013)
"Leptin is a nutritional cytokine, and it is closely related to the progression of cancer."1.91EGCG alleviates obesity-exacerbated lung cancer progression by STAT1/SLC7A11 pathway and gut microbiota. ( Gao, J; Hao, S; Jiang, P; Li, F, 2023)
"Chemical induced carcinogenesis together with genetically engineered mouse models represent important approaches for the study of the complex mechanisms involving genotype and environmental factors in cancer development, including lung cancer."1.62Urethane-induced lung carcinogenesis. ( Del Prete, A; Schioppa, T; Sozio, F; Sozzani, S, 2021)
"Lung cancer is the leading cause of cancer death worldwide."1.48Nrf2-activated expression of sulfiredoxin contributes to urethane-induced lung tumorigenesis. ( Chawsheen, HA; Gerard, M; Jiang, H; Mishra, M; Toledano, MB; Wei, Q, 2018)
"Urethane is a recognized genotoxic carcinogen in fermented foods and beverages."1.43Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro. ( Cao, N; Deng, J; Du, G; Duan, Y; Geng, S; Guo, Z; Lin, H; Ma, X; Meng, M; Zheng, Y, 2016)
"Urethane-induced lung carcinogenesis led to more M2 macrophage phenotype and increased abnormal angiogenesis concomitant with the upregulation of LC3-B and the downregulation of p62."1.43The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis. ( Cao, N; Du, GJ; Geng, SN; Guo, ZZ; Han, G; Li, GG; Lin, HH; Ma, XF; Meng, MJ; Zheng, YQ, 2016)
"Our data validate chemical carcinogenesis as a suitable "in vivo" model for further and more detailed studies on the molecular mechanisms of the death response induced by Col V in lung infiltrating adenocarcinoma opening new strategies for treatment."1.43Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model. ( Alveno, RA; Capelozzi, VL; Corrêa, PY; de Morais, J; Fabro, AT; Faustino, CB; Parra, ER; Rangel, MP; Teodoro, WR; Vargas, CM; Velosa, AP, 2016)
"Curcumin has long been recognized as a chemopreventive agent, but poor bioavailability and weak Nrf2 induction have prohibited clinical application."1.42A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response. ( Chapman, E; Chen, J; Jiang, T; Long, M; Ren, DM; Shen, T; Wong, PK; Zhang, DD; Zhou, B, 2015)
"LPS-induced pulmonary inflammation did not increase lung carcinogenesis, whereas decreased pulmonary inflammation by macrophage depletion promoted lung carcinogenesis."1.42The Combination of Three Natural Compounds Effectively Prevented Lung Carcinogenesis by Optimal Wound Healing. ( Cao, N; Du, G; Duan, Y; Geng, S; Guo, Z; Han, G; Li, H; Liu, L; Ma, X; Zheng, Y, 2015)
"During the carcinogenesis phase, no detectable Th1- or Th2-associated cytokine responses were observed, but levels of pro-inflammatory cytokines were increased with distinctive kinetics."1.39Antitumor effects of L-BLP25 antigen-specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model. ( DeGregorio, MW; Greenberg, BE; Griffey, SM; Gutierrez, AM; Kao, CJ; Vang, DP; Wolf, M; Wurz, GT, 2013)

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-199028 (49.12)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's20 (35.09)24.3611
2020's9 (15.79)2.80

Authors

AuthorsStudies
Li, S3
Counter, CM5
Satoh, H1
Arai, Y1
Furukawa, E1
Moriguchi, T1
Hama, N1
Urushidate, T1
Totoki, Y1
Kato, M1
Ohe, Y1
Yamamoto, M1
Shibata, T1
Li, F1
Hao, S1
Gao, J1
Jiang, P1
MacAlpine, DM2
Shibata, MA1
Shibata, E1
Morimoto, J1
Kondo, Y1
Zheng, J1
Guo, X1
Nakamura, Y1
Zhou, X1
Yamaguchi, R1
Zhang, J1
Ishigaki, Y1
Uramoto, H1
Yamada, S1
Sozio, F1
Schioppa, T1
Sozzani, S1
Del Prete, A1
Li, K1
Zheng, X1
Tang, H2
Zang, YS1
Zeng, C1
Liu, X1
Shen, Y1
Pang, Y1
Wang, S1
Xie, F1
Lu, X1
Luo, Y1
Li, Z2
Bi, W1
Jia, X1
Huang, T1
Wei, R1
Huang, K1
Chen, Z1
Zhu, Q1
He, Y1
Zhang, M2
Gu, Z1
Xiao, Y2
Zhang, X1
Fletcher, JA1
Wang, Y3
Mishra, M1
Jiang, H1
Chawsheen, HA1
Gerard, M1
Toledano, MB1
Wei, Q1
Kanellakis, NI1
Giannou, AD1
Pepe, MAA1
Agalioti, T1
Zazara, DE1
Giopanou, I1
Psallidas, I1
Spella, M1
Marazioti, A1
Arendt, KAM1
Lamort, AS1
Champeris Tsaniras, S1
Taraviras, S1
Papadaki, H1
Lilis, I1
Stathopoulos, GT1
Lin, Y1
Zhang, S1
Zhou, L1
Yan, G1
Wang, M1
Lin, H3
Tong, Q1
Duan, Y4
Du, G5
Wurz, GT1
Gutierrez, AM1
Greenberg, BE1
Vang, DP1
Griffey, SM1
Kao, CJ1
Wolf, M1
DeGregorio, MW1
Sun, T1
Zhang, Y1
Li, J2
Liu, W1
Zhao, B1
Li, H2
Liu, Y1
Jan Treda, C1
Fukuhara, T1
Suzuki, T1
Nakamura, A1
Zaini, J1
Kikuchi, T1
Ebina, M1
Nukiwa, T1
Huang, L1
Carney, J1
Cardona, DM1
Pershing, NL1
Lampson, BL1
Belsky, JA1
Kaltenbrun, E1
Lajovic, A1
Nagy, LD1
Guengerich, FP1
Bren, U1
Liao, Y1
Zhang, C1
Chen, G1
Xu, L1
Liu, Z1
Fu, S1
Yu, L1
Zhou, S1
Hashizume, O1
Yamanashi, H1
Taketo, MM1
Nakada, K1
Hayashi, J1
Shen, T1
Jiang, T1
Long, M1
Chen, J1
Ren, DM1
Wong, PK1
Chapman, E1
Zhou, B1
Zhang, DD1
Colombo, NB1
Rangel, MP2
Martins, V1
Hage, M1
Gelain, DP1
Barbeiro, DF1
Grisolia, CK1
Parra, ER2
Capelozzi, VL2
Sun, F1
Qu, Z1
Zhou, J1
Burns, TF1
Stabile, LP1
Siegfried, JM1
Xiao, G1
Ma, X3
Deng, J1
Cao, N4
Guo, Z3
Zheng, Y3
Geng, S3
Meng, M2
Liu, L1
Han, G2
Li, GG1
Guo, ZZ1
Ma, XF1
Geng, SN1
Zheng, YQ1
Meng, MJ1
Lin, HH1
Du, GJ1
Malanga, D1
Belmonte, S1
Colelli, F1
Scarfò, M1
De Marco, C1
Oliveira, DM1
Mirante, T1
Camastra, C1
Gagliardi, M1
Rizzuto, A1
Mignogna, C1
Paciello, O1
Papparella, S1
Fagman, H1
Viglietto, G1
Alveno, RA1
Faustino, CB1
Corrêa, PY1
Vargas, CM1
de Morais, J1
Velosa, AP1
Fabro, AT1
Teodoro, WR1
Du, Z1
HARAN, N1
BERENBLUM, I8
HARAN-GHERA, N3
RITCHIE, AC1
PARMEGGIANI, A1
MALTONI, C2
PRODI, G2
KAWAMOTO, S1
IDA, N1
KIRSCHBAUM, A1
TAYLOR, G1
FIORE-DONATI, L4
CHIECO-BIANCHI, L4
DE BENEDICTIS, G2
MAIORANO, G3
TANNENBAUM, A2
BEN-ISHAI, D1
LAPIDOT, A1
SIMON, E1
TRAININ, N7
BLUM, B1
REWALD, FE1
SCHRAMM, T1
TOTH, B1
TOMATIS, L2
SHUBIK, P2
DEBENEDICTIS, G2
TRIDENTE, G1
KAYE, AM3
PRECERUTTI, A1
LAW, LW1
SKJAEGGESTAD, O1
LIEBELT, RA1
LIEBELT, AG1
LANE, M1
SCHMAEHL, D1
THOMAS, C1
BRUNE, H1

Other Studies

57 other studies available for urethane and Carcinogenesis

ArticleYear
Non-canonical genomic driver mutations of urethane carcinogenesis.
    PloS one, 2022, Volume: 17, Issue:4

    Topics: Animals; Carcinogenesis; Carcinogens; Genomics; Lung Neoplasms; Mice; Mutation; Nucleotides; Proto-O

2022
Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels.
    Carcinogenesis, 2022, 08-30, Volume: 43, Issue:7

    Topics: Animals; Carcinogenesis; Disease Models, Animal; Genomics; Humans; Kelch-Like ECH-Associated Protein

2022
EGCG alleviates obesity-exacerbated lung cancer progression by STAT1/SLC7A11 pathway and gut microbiota.
    The Journal of nutritional biochemistry, 2023, Volume: 120

    Topics: Animals; Carcinogenesis; Diet, High-Fat; Gastrointestinal Microbiome; Leptin; Lung; Lung Neoplasms;

2023
Capturing the primordial Kras mutation initiating urethane carcinogenesis.
    Nature communications, 2020, 04-14, Volume: 11, Issue:1

    Topics: Animals; Carcinogenesis; Female; Genome; Humans; Male; Mammals; Mice; Mutation; Mutation Rate; Organ

2020
Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor.
    Anticancer research, 2020, Volume: 40, Issue:5

    Topics: Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Female; Genes, Dominant; Lung Neoplasms; Mam

2020
Overexpression of PRDX4 Modulates Tumor Microenvironment and Promotes Urethane-Induced Lung Tumorigenesis.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Humans; Interleukin-1beta; Lung Neoplasms; M

2020
Urethane-induced lung carcinogenesis.
    Methods in cell biology, 2021, Volume: 163

    Topics: Animals; Carcinogenesis; Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Urethane

2021
Signaling levels mold the RAS mutation tropism of urethane.
    eLife, 2021, 05-17, Volume: 10

    Topics: Animals; Carcinogenesis; Cell Transformation, Neoplastic; Genes, ras; Lung Neoplasms; Mice; Mice, 12

2021
E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.
    The Journal of experimental medicine, 2021, 08-02, Volume: 218, Issue:8

    Topics: Amino Acid Sequence; Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell

2021
Nrf2-activated expression of sulfiredoxin contributes to urethane-induced lung tumorigenesis.
    Cancer letters, 2018, 09-28, Volume: 432

    Topics: Animals; Apoptosis; Carcinogenesis; Carcinogens; Cell Proliferation; Cells, Cultured; Female; Gene E

2018
Tobacco chemical-induced mouse lung adenocarcinoma cell lines pin the prolactin orthologue proliferin as a lung tumour promoter.
    Carcinogenesis, 2019, Nov-25, Volume: 40, Issue:11

    Topics: Adenocarcinoma of Lung; Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Diethylnitrosamine;

2019
Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis.
    Journal of translational medicine, 2019, 03-18, Volume: 17, Issue:1

    Topics: Allografts; Animals; Blood Coagulation Disorders; Carcinogenesis; Carcinoma, Lewis Lung; Emodin; Ext

2019
Antitumor effects of L-BLP25 antigen-specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model.
    Journal of translational medicine, 2013, Mar-13, Volume: 11

    Topics: Adenoma; Animals; Antigens, Neoplasm; Cancer Vaccines; Carcinogenesis; Cyclophosphamide; Cytokines;

2013
The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis.
    European journal of pharmacology, 2013, Sep-05, Volume: 715, Issue:1-3

    Topics: Animals; Carcinogenesis; Disease Progression; Disease Susceptibility; DNA, Mitochondrial; Electron T

2013
Secretory leukocyte protease inhibitor modulates urethane-induced lung carcinogenesis.
    Carcinogenesis, 2014, Volume: 35, Issue:4

    Topics: Adenocarcinoma; Animals; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; DNA Pr

2014
Decreased tumorigenesis in mice with a Kras point mutation at C118.
    Nature communications, 2014, Nov-14, Volume: 5

    Topics: Alleles; Animals; Carcinogenesis; Carcinogens; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57B

2014
Rare codons capacitate Kras-driven de novo tumorigenesis.
    The Journal of clinical investigation, 2015, Volume: 125, Issue:1

    Topics: Adenoma; Animals; Carcinogenesis; Cell Proliferation; Cells, Cultured; Codon; Female; Humans; Lung N

2015
Carcinogenesis of urethane: simulation versus experiment.
    Chemical research in toxicology, 2015, Apr-20, Volume: 28, Issue:4

    Topics: Carcinogenesis; Carcinogens; DNA; Hydrolysis; Quantum Theory; Thermodynamics; Urethane

2015
Fulvestrant-mediated inhibition of estrogen receptor signaling slows lung cancer progression.
    Oncology research, 2014, Volume: 22, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents, Hormonal; Carcinogenesis; Disease Model

2014
A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNA.
    PloS one, 2015, Volume: 10, Issue:3

    Topics: Adenoma; AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Nuc

2015
A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response.
    Antioxidants & redox signaling, 2015, Sep-10, Volume: 23, Issue:8

    Topics: Acetone; Animals; Anticarcinogenic Agents; Arsenites; Benzyl Compounds; Carcinogenesis; Cell Line, T

2015
Caryocar brasiliense camb protects against genomic and oxidative damage in urethane-induced lung carcinogenesis.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2015, Volume: 48, Issue:9

    Topics: Animals; Antioxidants; Carcinogenesis; Carcinogens; Comet Assay; DNA Damage; Ericales; Genome; Immun

2015
NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function.
    Oncogene, 2016, 05-05, Volume: 35, Issue:18

    Topics: Animals; Carcinogenesis; Cell Line, Tumor; Enzyme Stability; Gene Knockout Techniques; Genes, ras; H

2016
Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro.
    Toxicology letters, 2016, Jan-05, Volume: 240, Issue:1

    Topics: Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Deoxyglucose; Disease Models, Animal; Diseas

2016
The Combination of Three Natural Compounds Effectively Prevented Lung Carcinogenesis by Optimal Wound Healing.
    PloS one, 2015, Volume: 10, Issue:11

    Topics: Animals; Apoptosis; Biological Products; Body Weight; Carcinogenesis; Cell Differentiation; Cell Lin

2015
The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis.
    Developmental and comparative immunology, 2016, Volume: 59

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Apoptosis; Autophagy; Benzofurans; Capillary Permea

2016
AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Animals; Bronchi; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Epithelial Cells; Fe

2016
Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model.
    Archivum immunologiae et therapiae experimentalis, 2016, Volume: 64, Issue:4

    Topics: Administration, Intranasal; Animals; Apoptosis; Carcinogenesis; Collagen Type V; DNA Fragmentation;

2016
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
    Journal of agricultural and food chemistry, 2016, Aug-10, Volume: 64, Issue:31

    Topics: Animals; Capsaicin; Carcinogenesis; Catechols; Disease Models, Animal; ErbB Receptors; Fatty Alcohol

2016
The induction of the initiating phase of skin carcinogenesis in the mouse by oral administration of urethane (ethyl carbamate).
    British journal of cancer, 1956, Volume: 10, Issue:1

    Topics: Administration, Oral; Animals; Carcinogenesis; Mice; Neoplasms, Experimental; Urethane

1956
A quantitative study of the systemic initiating action of urethane (ethyl carbamate) in mouse skin carcinogenesis.
    British journal of cancer, 1957, Volume: 11, Issue:1

    Topics: Animals; Carcinogenesis; Mice; Neoplasms, Experimental; Skin Neoplasms; Urethane

1957
Epidermal carcinogenesis in the mouse by intraperitoneally administered urethane followed by repeated applications of croton oil.
    British journal of cancer, 1957, Volume: 11, Issue:2

    Topics: Animals; Carcinogenesis; Carcinogens; Croton Oil; Epidermis; Mice; Neoplasms, Experimental; Skin Neo

1957
[Experimental studies of the diphasic doctrine of cutaneous carcinogenesis in various animal species. I. Effect of urethane (initiating factor) and of croton oil and tween 60 (promoting factors); experiments with rabbits].
    Bollettino della Societa italiana di biologia sperimentale, 1957, Volume: 33, Issue:7

    Topics: Animals; Carcinogenesis; Croton Oil; Lagomorpha; Neoplasms, Experimental; Polysorbates; Rabbits; Ski

1957
Urethan and leukemogenesis in mice.
    Cancer research, 1958, Volume: 18, Issue:6

    Topics: Animals; Carcinogenesis; Leukemia; Leukemia, Experimental; Mice; Urethane

1958
[Effects of urethane on 9, 10-dimethyl-1, 2-benzanthracene carcinogenesis in rats].
    Bollettino della Societa italiana di biologia sperimentale, 1959, Jan-31, Volume: 35, Issue:2

    Topics: Animals; Anthracenes; Benz(a)Anthracenes; Carcinogenesis; Rats; Urethane

1959
Leukaemogenesis by urethan in new-born Swiss mice.
    Nature, 1961, Apr-15, Volume: 190

    Topics: Animals; Carcinogenesis; Leukemia; Leukemia, Experimental; Mice; Urethane

1961
Studies on urethan carcinogenesis.
    Acta - Unio Internationalis Contra Cancrum, 1961, Volume: 17

    Topics: Carcinogenesis; Carcinogens; Humans; Urethane

1961
Skin initiating action and lung carcinogenesis byderivatives of urethane (ethyl carbamate) and related compounds.
    Biochemical pharmacology, 1959, Volume: 2

    Topics: Animals; Carcinogenesis; Carcinogens; Humans; Lung; Lung Neoplasms; Neoplasms, Experimental; Skin Ne

1959
Failure of the urethane antagonist-lysergic acid-diethylamide (LSD-25)--to inhibit lung carcinogenesis or the initiating phase of skin carcinogenesis in mice.
    Biochemical pharmacology, 1959, Volume: 2

    Topics: Animals; Carcinogenesis; Lung Neoplasms; Lysergic Acid Diethylamide; Mice; Neoplasms, Experimental;

1959
Possible two-stage mechanism in experimental leukemogenesis.
    Science (New York, N.Y.), 1960, Jul-01, Volume: 132, Issue:3418

    Topics: Animals; Carcinogenesis; Leukemia, Experimental; Mice; Research; Urethane

1960
Failure of bone marrow to interfere with the augmentation of x-ray leukemogenesis by urethan.
    Journal of the National Cancer Institute, 1961, Volume: 27

    Topics: Animals; Bone Marrow; Carcinogenesis; Leukemia; Leukemia, Experimental; Radiation Protection; Uretha

1961
Leukemogenesis by urethan in C57B1 mice bearing isologous tissues from x-irradiated mice.
    Science (New York, N.Y.), 1961, Dec-22, Volume: 134, Issue:3495

    Topics: Animals; Carcinogenesis; Injections; Leukemia, Experimental; Mice; Radiation Effects; Transplantatio

1961
[The effect of fatty acids on carcinogenesis. IV. On experiments on inhibition of 20-methylcholanthrene, 9-10-dimenthyl-1, 2-methylcholanthrene, 9-10-dimethyl-1,2-benzanthracene and urethane-induced carcinogenesis by means of linolenic acid].
    Acta biologica et medica Germanica, 1961, Volume: 7

    Topics: alpha-Linolenic Acid; Arachidonic Acid; Benz(a)Anthracenes; Carcinogenesis; Fatty Acids; Methylchola

1961
Multipotential carcinogenesis with urethan in the Syrian golden hamster.
    Cancer research, 1961, Volume: 21

    Topics: Animals; Carcinogenesis; Cricetinae; Mesocricetus; Urethane

1961
Influence of urethane on subcutaneous carcinogenesis by "Teflon" implants.
    Nature, 1963, May-11, Volume: 198

    Topics: Carcinogenesis; Neoplasms; Plastics; Polytetrafluoroethylene; Prostheses and Implants; Sarcoma; Sarc

1963
Lung carcinogenesis by urethane in newborn, suckling, and adult Swiss mice.
    British journal of cancer, 1962, Volume: 16

    Topics: Animals; Animals, Newborn; Carcinogenesis; Lung Neoplasms; Mice; Urethane

1962
INFLUENCE OF AGE AND ROUTE OF ADMINISTRATION ON LUNG CARCINOGENESIS BY URETHAN IN SWISS MICE.
    Acta - Unio Internationalis Contra Cancrum, 1963, Volume: 19

    Topics: Adenoma; Animals; Animals, Newborn; Carcinogenesis; Female; Humans; Lactation; Lung Neoplasms; Mice;

1963
THE MECHANISM OF CARCINOGENESIS IN BREAST TUMOUR DEVELOPMENT IN MICE.
    Acta - Unio Internationalis Contra Cancrum, 1963, Volume: 19

    Topics: Animals; Breast Neoplasms; Carcinogenesis; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Exp

1963
INFLUENCE OF AGE ON SUSCEPTIBILITY TO LIVER CARCINOGENESIS AND SKIN INITIATING ACTION BY URETHANE IN SWISS MICE.
    British journal of cancer, 1963, Volume: 17

    Topics: Aging; Animals; Animals, Newborn; Carcinogenesis; Carcinoma, Hepatocellular; Croton Oil; Female; Hum

1963
INFLUENCE OF MUTAGENS ON THE INITIATION OF SKIN CARCINOGENESIS.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: 2-Aminopurine; Acridines; Adenine; Carcinogenesis; Carcinogens; Idoxuridine; Lung Neoplasms; Mice; M

1964
CONTRIBUTION OF URETHAN STUDIES TO THE UNDERSTANDING OF CARCINOGENESIS.
    National Cancer Institute monograph, 1964, Volume: 14

    Topics: Adenoma; Animals; Carcinogenesis; Carcinogens; Cricetinae; Mammary Neoplasms, Animal; Mammary Neopla

1964
TRENDS IN CARCINOGENESIS BY URETHAN ADMINISTRATION TO NEW-BORN MICE OF DIFFERENT STRAINS.
    Nature, 1964, Apr-18, Volume: 202

    Topics: Adenoma; Animals; Animals, Newborn; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Genetics

1964
EXPERIMENTAL EPIDERMAL HYPERPLASIA IN MICE: RELATION TO CARCINOGENESIS.
    Acta pathologica et microbiologica Scandinavica. Supplementum, 1964

    Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Cantharidin; Carcinogenesis; Carcinogens; Cell Division;

1964
HORMONAL INFLUENCES ON URETHAN CARCINOGENESIS IN C3H/F MICE.
    Cancer research, 1964, Volume: 24

    Topics: Adrenal Gland Neoplasms; Androgens; Animals; Animals, Newborn; Carcinogenesis; Carcinogens; Carcinom

1964
[EXPERIMENTAL STUDIES ON SYNCARCINOGENESIS. II. STUDIES ON CARCINOGENESIS IN MICE IN THE SIMULTANEOUS APPLICATION OF URETHANE AND 9,10-DIMETHYL-1,2-BENZANTHRACENE].
    Zeitschrift fur Krebsforschung, 1964, Nov-02, Volume: 66

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Carcinogenesis; Carcinogens; Mice; Neoplasms;

1964
Chromatographic studies in relation to ethyl carbamate (urethan) carcinogenesis using C14-labeled compounds.
    Cancer research, 1960, Volume: 20

    Topics: Animals; Carcinogenesis; Carcinogens; Neoplasms, Experimental; Urethane

1960
A study of the relationship between the rate of ethyl carbamate (urethan) catabolism and urethan carcinogenesis.
    Cancer research, 1960, Volume: 20

    Topics: Carcinogenesis; Carcinogens; Humans; Urethane

1960