urethane has been researched along with Carcinogenesis in 57 studies
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
Excerpt | Relevance | Reference |
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"To analyze whether TGF-β exerts suppressive or oncogenic actions on mammary carcinogenesis, transgenic mice overexpressing a dominant-negative mutant type II TGF-β receptor (TβRII-DNR) driven by the mouse mammary tumor virus (MMTV) promoter were treated with a low dose of urethane, a carcinogen present in fermented food products and alcoholic beverages." | 7.96 | Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor. ( Kondo, Y; Morimoto, J; Shibata, E; Shibata, MA, 2020) |
"This study suggests a novel function of emodin, whereby it selectively suppresses N2 neutrophils to prevent hypercoagulation and lung carcinogenesis." | 7.91 | Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis. ( Du, G; Duan, Y; Li, Z; Lin, H; Lin, Y; Tong, Q; Wang, M; Wang, Y; Yan, G; Zhang, M; Zhang, S; Zhou, L, 2019) |
"The carcinogenesis of urethane (ethyl carbamate), a byproduct of fermentation that is consistently found in various food products, was investigated with a combination of kinetic experiments and quantum chemical calculations." | 7.81 | Carcinogenesis of urethane: simulation versus experiment. ( Bren, U; Guengerich, FP; Lajovic, A; Nagy, LD, 2015) |
" The current study explored whether mitochondrial dysfunction correlated with urethane-induced lung carcinogenesis in BALB/c and C57BL/6 mice that were given single- or multi-dose intraperitoneal injections of urethane." | 7.79 | The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis. ( Du, G; Li, H; Li, J; Lin, H; Liu, W; Liu, Y; Sun, T; Wang, Y; Zhang, Y; Zhao, B, 2013) |
"Chemical induced carcinogenesis together with genetically engineered mouse models represent important approaches for the study of the complex mechanisms involving genotype and environmental factors in cancer development, including lung cancer." | 5.62 | Urethane-induced lung carcinogenesis. ( Del Prete, A; Schioppa, T; Sozio, F; Sozzani, S, 2021) |
"Urethane is a recognized genotoxic carcinogen in fermented foods and beverages." | 5.43 | Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro. ( Cao, N; Deng, J; Du, G; Duan, Y; Geng, S; Guo, Z; Lin, H; Ma, X; Meng, M; Zheng, Y, 2016) |
"Urethane-induced lung carcinogenesis led to more M2 macrophage phenotype and increased abnormal angiogenesis concomitant with the upregulation of LC3-B and the downregulation of p62." | 5.43 | The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis. ( Cao, N; Du, GJ; Geng, SN; Guo, ZZ; Han, G; Li, GG; Lin, HH; Ma, XF; Meng, MJ; Zheng, YQ, 2016) |
"Our data validate chemical carcinogenesis as a suitable "in vivo" model for further and more detailed studies on the molecular mechanisms of the death response induced by Col V in lung infiltrating adenocarcinoma opening new strategies for treatment." | 5.43 | Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model. ( Alveno, RA; Capelozzi, VL; Corrêa, PY; de Morais, J; Fabro, AT; Faustino, CB; Parra, ER; Rangel, MP; Teodoro, WR; Vargas, CM; Velosa, AP, 2016) |
"Curcumin has long been recognized as a chemopreventive agent, but poor bioavailability and weak Nrf2 induction have prohibited clinical application." | 5.42 | A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response. ( Chapman, E; Chen, J; Jiang, T; Long, M; Ren, DM; Shen, T; Wong, PK; Zhang, DD; Zhou, B, 2015) |
" We elucidated the relationship between Nrf2 expression levels and whole exon mutation patterns using an ethyl-carbamate (urethane)-induced lung carcinogenesis model employing Nrf2-deficient and Keap1-kd mice, the latter of which express high levels of Nrf2." | 4.12 | Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels. ( Arai, Y; Furukawa, E; Hama, N; Kato, M; Moriguchi, T; Ohe, Y; Satoh, H; Shibata, T; Totoki, Y; Urushidate, T; Yamamoto, M, 2022) |
"To analyze whether TGF-β exerts suppressive or oncogenic actions on mammary carcinogenesis, transgenic mice overexpressing a dominant-negative mutant type II TGF-β receptor (TβRII-DNR) driven by the mouse mammary tumor virus (MMTV) promoter were treated with a low dose of urethane, a carcinogen present in fermented food products and alcoholic beverages." | 3.96 | Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor. ( Kondo, Y; Morimoto, J; Shibata, E; Shibata, MA, 2020) |
"This study suggests a novel function of emodin, whereby it selectively suppresses N2 neutrophils to prevent hypercoagulation and lung carcinogenesis." | 3.91 | Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis. ( Du, G; Duan, Y; Li, Z; Lin, H; Lin, Y; Tong, Q; Wang, M; Wang, Y; Yan, G; Zhang, M; Zhang, S; Zhou, L, 2019) |
" In conclusion, AKT1E17K induces hyperplasia of mouse lung epithelium in vivo and cooperates with urethane to induce the fully malignant phenotype." | 3.83 | AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer. ( Belmonte, S; Camastra, C; Colelli, F; De Marco, C; Fagman, H; Gagliardi, M; Malanga, D; Mignogna, C; Mirante, T; Oliveira, DM; Paciello, O; Papparella, S; Rizzuto, A; Scarfò, M; Viglietto, G, 2016) |
" A mouse model of urethane-induced lung adenocarcinoma was used in the study." | 3.80 | Fulvestrant-mediated inhibition of estrogen receptor signaling slows lung cancer progression. ( Chen, G; Fu, S; Liao, Y; Liu, Z; Tang, H; Xu, L; Yu, L; Zhang, C; Zhou, S, 2014) |
" The current study explored whether mitochondrial dysfunction correlated with urethane-induced lung carcinogenesis in BALB/c and C57BL/6 mice that were given single- or multi-dose intraperitoneal injections of urethane." | 3.79 | The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis. ( Du, G; Li, H; Li, J; Lin, H; Liu, W; Liu, Y; Sun, T; Wang, Y; Zhang, Y; Zhao, B, 2013) |
"Leptin is a nutritional cytokine, and it is closely related to the progression of cancer." | 1.91 | EGCG alleviates obesity-exacerbated lung cancer progression by STAT1/SLC7A11 pathway and gut microbiota. ( Gao, J; Hao, S; Jiang, P; Li, F, 2023) |
"Chemical induced carcinogenesis together with genetically engineered mouse models represent important approaches for the study of the complex mechanisms involving genotype and environmental factors in cancer development, including lung cancer." | 1.62 | Urethane-induced lung carcinogenesis. ( Del Prete, A; Schioppa, T; Sozio, F; Sozzani, S, 2021) |
"Lung cancer is the leading cause of cancer death worldwide." | 1.48 | Nrf2-activated expression of sulfiredoxin contributes to urethane-induced lung tumorigenesis. ( Chawsheen, HA; Gerard, M; Jiang, H; Mishra, M; Toledano, MB; Wei, Q, 2018) |
"Urethane is a recognized genotoxic carcinogen in fermented foods and beverages." | 1.43 | Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro. ( Cao, N; Deng, J; Du, G; Duan, Y; Geng, S; Guo, Z; Lin, H; Ma, X; Meng, M; Zheng, Y, 2016) |
"Urethane-induced lung carcinogenesis led to more M2 macrophage phenotype and increased abnormal angiogenesis concomitant with the upregulation of LC3-B and the downregulation of p62." | 1.43 | The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis. ( Cao, N; Du, GJ; Geng, SN; Guo, ZZ; Han, G; Li, GG; Lin, HH; Ma, XF; Meng, MJ; Zheng, YQ, 2016) |
"Our data validate chemical carcinogenesis as a suitable "in vivo" model for further and more detailed studies on the molecular mechanisms of the death response induced by Col V in lung infiltrating adenocarcinoma opening new strategies for treatment." | 1.43 | Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model. ( Alveno, RA; Capelozzi, VL; Corrêa, PY; de Morais, J; Fabro, AT; Faustino, CB; Parra, ER; Rangel, MP; Teodoro, WR; Vargas, CM; Velosa, AP, 2016) |
"Curcumin has long been recognized as a chemopreventive agent, but poor bioavailability and weak Nrf2 induction have prohibited clinical application." | 1.42 | A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response. ( Chapman, E; Chen, J; Jiang, T; Long, M; Ren, DM; Shen, T; Wong, PK; Zhang, DD; Zhou, B, 2015) |
"LPS-induced pulmonary inflammation did not increase lung carcinogenesis, whereas decreased pulmonary inflammation by macrophage depletion promoted lung carcinogenesis." | 1.42 | The Combination of Three Natural Compounds Effectively Prevented Lung Carcinogenesis by Optimal Wound Healing. ( Cao, N; Du, G; Duan, Y; Geng, S; Guo, Z; Han, G; Li, H; Liu, L; Ma, X; Zheng, Y, 2015) |
"During the carcinogenesis phase, no detectable Th1- or Th2-associated cytokine responses were observed, but levels of pro-inflammatory cytokines were increased with distinctive kinetics." | 1.39 | Antitumor effects of L-BLP25 antigen-specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model. ( DeGregorio, MW; Greenberg, BE; Griffey, SM; Gutierrez, AM; Kao, CJ; Vang, DP; Wolf, M; Wurz, GT, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 28 (49.12) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 20 (35.09) | 24.3611 |
2020's | 9 (15.79) | 2.80 |
Authors | Studies |
---|---|
Li, S | 3 |
Counter, CM | 5 |
Satoh, H | 1 |
Arai, Y | 1 |
Furukawa, E | 1 |
Moriguchi, T | 1 |
Hama, N | 1 |
Urushidate, T | 1 |
Totoki, Y | 1 |
Kato, M | 1 |
Ohe, Y | 1 |
Yamamoto, M | 1 |
Shibata, T | 1 |
Li, F | 1 |
Hao, S | 1 |
Gao, J | 1 |
Jiang, P | 1 |
MacAlpine, DM | 2 |
Shibata, MA | 1 |
Shibata, E | 1 |
Morimoto, J | 1 |
Kondo, Y | 1 |
Zheng, J | 1 |
Guo, X | 1 |
Nakamura, Y | 1 |
Zhou, X | 1 |
Yamaguchi, R | 1 |
Zhang, J | 1 |
Ishigaki, Y | 1 |
Uramoto, H | 1 |
Yamada, S | 1 |
Sozio, F | 1 |
Schioppa, T | 1 |
Sozzani, S | 1 |
Del Prete, A | 1 |
Li, K | 1 |
Zheng, X | 1 |
Tang, H | 2 |
Zang, YS | 1 |
Zeng, C | 1 |
Liu, X | 1 |
Shen, Y | 1 |
Pang, Y | 1 |
Wang, S | 1 |
Xie, F | 1 |
Lu, X | 1 |
Luo, Y | 1 |
Li, Z | 2 |
Bi, W | 1 |
Jia, X | 1 |
Huang, T | 1 |
Wei, R | 1 |
Huang, K | 1 |
Chen, Z | 1 |
Zhu, Q | 1 |
He, Y | 1 |
Zhang, M | 2 |
Gu, Z | 1 |
Xiao, Y | 2 |
Zhang, X | 1 |
Fletcher, JA | 1 |
Wang, Y | 3 |
Mishra, M | 1 |
Jiang, H | 1 |
Chawsheen, HA | 1 |
Gerard, M | 1 |
Toledano, MB | 1 |
Wei, Q | 1 |
Kanellakis, NI | 1 |
Giannou, AD | 1 |
Pepe, MAA | 1 |
Agalioti, T | 1 |
Zazara, DE | 1 |
Giopanou, I | 1 |
Psallidas, I | 1 |
Spella, M | 1 |
Marazioti, A | 1 |
Arendt, KAM | 1 |
Lamort, AS | 1 |
Champeris Tsaniras, S | 1 |
Taraviras, S | 1 |
Papadaki, H | 1 |
Lilis, I | 1 |
Stathopoulos, GT | 1 |
Lin, Y | 1 |
Zhang, S | 1 |
Zhou, L | 1 |
Yan, G | 1 |
Wang, M | 1 |
Lin, H | 3 |
Tong, Q | 1 |
Duan, Y | 4 |
Du, G | 5 |
Wurz, GT | 1 |
Gutierrez, AM | 1 |
Greenberg, BE | 1 |
Vang, DP | 1 |
Griffey, SM | 1 |
Kao, CJ | 1 |
Wolf, M | 1 |
DeGregorio, MW | 1 |
Sun, T | 1 |
Zhang, Y | 1 |
Li, J | 2 |
Liu, W | 1 |
Zhao, B | 1 |
Li, H | 2 |
Liu, Y | 1 |
Jan Treda, C | 1 |
Fukuhara, T | 1 |
Suzuki, T | 1 |
Nakamura, A | 1 |
Zaini, J | 1 |
Kikuchi, T | 1 |
Ebina, M | 1 |
Nukiwa, T | 1 |
Huang, L | 1 |
Carney, J | 1 |
Cardona, DM | 1 |
Pershing, NL | 1 |
Lampson, BL | 1 |
Belsky, JA | 1 |
Kaltenbrun, E | 1 |
Lajovic, A | 1 |
Nagy, LD | 1 |
Guengerich, FP | 1 |
Bren, U | 1 |
Liao, Y | 1 |
Zhang, C | 1 |
Chen, G | 1 |
Xu, L | 1 |
Liu, Z | 1 |
Fu, S | 1 |
Yu, L | 1 |
Zhou, S | 1 |
Hashizume, O | 1 |
Yamanashi, H | 1 |
Taketo, MM | 1 |
Nakada, K | 1 |
Hayashi, J | 1 |
Shen, T | 1 |
Jiang, T | 1 |
Long, M | 1 |
Chen, J | 1 |
Ren, DM | 1 |
Wong, PK | 1 |
Chapman, E | 1 |
Zhou, B | 1 |
Zhang, DD | 1 |
Colombo, NB | 1 |
Rangel, MP | 2 |
Martins, V | 1 |
Hage, M | 1 |
Gelain, DP | 1 |
Barbeiro, DF | 1 |
Grisolia, CK | 1 |
Parra, ER | 2 |
Capelozzi, VL | 2 |
Sun, F | 1 |
Qu, Z | 1 |
Zhou, J | 1 |
Burns, TF | 1 |
Stabile, LP | 1 |
Siegfried, JM | 1 |
Xiao, G | 1 |
Ma, X | 3 |
Deng, J | 1 |
Cao, N | 4 |
Guo, Z | 3 |
Zheng, Y | 3 |
Geng, S | 3 |
Meng, M | 2 |
Liu, L | 1 |
Han, G | 2 |
Li, GG | 1 |
Guo, ZZ | 1 |
Ma, XF | 1 |
Geng, SN | 1 |
Zheng, YQ | 1 |
Meng, MJ | 1 |
Lin, HH | 1 |
Du, GJ | 1 |
Malanga, D | 1 |
Belmonte, S | 1 |
Colelli, F | 1 |
Scarfò, M | 1 |
De Marco, C | 1 |
Oliveira, DM | 1 |
Mirante, T | 1 |
Camastra, C | 1 |
Gagliardi, M | 1 |
Rizzuto, A | 1 |
Mignogna, C | 1 |
Paciello, O | 1 |
Papparella, S | 1 |
Fagman, H | 1 |
Viglietto, G | 1 |
Alveno, RA | 1 |
Faustino, CB | 1 |
Corrêa, PY | 1 |
Vargas, CM | 1 |
de Morais, J | 1 |
Velosa, AP | 1 |
Fabro, AT | 1 |
Teodoro, WR | 1 |
Du, Z | 1 |
HARAN, N | 1 |
BERENBLUM, I | 8 |
HARAN-GHERA, N | 3 |
RITCHIE, AC | 1 |
PARMEGGIANI, A | 1 |
MALTONI, C | 2 |
PRODI, G | 2 |
KAWAMOTO, S | 1 |
IDA, N | 1 |
KIRSCHBAUM, A | 1 |
TAYLOR, G | 1 |
FIORE-DONATI, L | 4 |
CHIECO-BIANCHI, L | 4 |
DE BENEDICTIS, G | 2 |
MAIORANO, G | 3 |
TANNENBAUM, A | 2 |
BEN-ISHAI, D | 1 |
LAPIDOT, A | 1 |
SIMON, E | 1 |
TRAININ, N | 7 |
BLUM, B | 1 |
REWALD, FE | 1 |
SCHRAMM, T | 1 |
TOTH, B | 1 |
TOMATIS, L | 2 |
SHUBIK, P | 2 |
DEBENEDICTIS, G | 2 |
TRIDENTE, G | 1 |
KAYE, AM | 3 |
PRECERUTTI, A | 1 |
LAW, LW | 1 |
SKJAEGGESTAD, O | 1 |
LIEBELT, RA | 1 |
LIEBELT, AG | 1 |
LANE, M | 1 |
SCHMAEHL, D | 1 |
THOMAS, C | 1 |
BRUNE, H | 1 |
57 other studies available for urethane and Carcinogenesis
Article | Year |
---|---|
Non-canonical genomic driver mutations of urethane carcinogenesis.
Topics: Animals; Carcinogenesis; Carcinogens; Genomics; Lung Neoplasms; Mice; Mutation; Nucleotides; Proto-O | 2022 |
Genomic landscape of chemical-induced lung tumors under Nrf2 different expression levels.
Topics: Animals; Carcinogenesis; Disease Models, Animal; Genomics; Humans; Kelch-Like ECH-Associated Protein | 2022 |
EGCG alleviates obesity-exacerbated lung cancer progression by STAT1/SLC7A11 pathway and gut microbiota.
Topics: Animals; Carcinogenesis; Diet, High-Fat; Gastrointestinal Microbiome; Leptin; Lung; Lung Neoplasms; | 2023 |
Capturing the primordial Kras mutation initiating urethane carcinogenesis.
Topics: Animals; Carcinogenesis; Female; Genome; Humans; Male; Mammals; Mice; Mutation; Mutation Rate; Organ | 2020 |
Urethane-induced Mammary Carcinogenesis Susceptibility in Transgenic Mice Expressing a Dominant-negative TGF-β Type II Receptor.
Topics: Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Female; Genes, Dominant; Lung Neoplasms; Mam | 2020 |
Overexpression of PRDX4 Modulates Tumor Microenvironment and Promotes Urethane-Induced Lung Tumorigenesis.
Topics: Animals; Apoptosis; Carcinogenesis; Cell Proliferation; Humans; Interleukin-1beta; Lung Neoplasms; M | 2020 |
Urethane-induced lung carcinogenesis.
Topics: Animals; Carcinogenesis; Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Urethane | 2021 |
Signaling levels mold the RAS mutation tropism of urethane.
Topics: Animals; Carcinogenesis; Cell Transformation, Neoplastic; Genes, ras; Lung Neoplasms; Mice; Mice, 12 | 2021 |
E3 ligase MKRN3 is a tumor suppressor regulating PABPC1 ubiquitination in non-small cell lung cancer.
Topics: Amino Acid Sequence; Animals; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell | 2021 |
Nrf2-activated expression of sulfiredoxin contributes to urethane-induced lung tumorigenesis.
Topics: Animals; Apoptosis; Carcinogenesis; Carcinogens; Cell Proliferation; Cells, Cultured; Female; Gene E | 2018 |
Tobacco chemical-induced mouse lung adenocarcinoma cell lines pin the prolactin orthologue proliferin as a lung tumour promoter.
Topics: Adenocarcinoma of Lung; Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Diethylnitrosamine; | 2019 |
Emodin regulates neutrophil phenotypes to prevent hypercoagulation and lung carcinogenesis.
Topics: Allografts; Animals; Blood Coagulation Disorders; Carcinogenesis; Carcinoma, Lewis Lung; Emodin; Ext | 2019 |
Antitumor effects of L-BLP25 antigen-specific tumor immunotherapy in a novel human MUC1 transgenic lung cancer mouse model.
Topics: Adenoma; Animals; Antigens, Neoplasm; Cancer Vaccines; Carcinogenesis; Cyclophosphamide; Cytokines; | 2013 |
The mitochondrial dysfunction plays an important role in urethane-induced lung carcinogenesis.
Topics: Animals; Carcinogenesis; Disease Progression; Disease Susceptibility; DNA, Mitochondrial; Electron T | 2013 |
Secretory leukocyte protease inhibitor modulates urethane-induced lung carcinogenesis.
Topics: Adenocarcinoma; Animals; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; DNA Pr | 2014 |
Decreased tumorigenesis in mice with a Kras point mutation at C118.
Topics: Alleles; Animals; Carcinogenesis; Carcinogens; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57B | 2014 |
Rare codons capacitate Kras-driven de novo tumorigenesis.
Topics: Adenoma; Animals; Carcinogenesis; Cell Proliferation; Cells, Cultured; Codon; Female; Humans; Lung N | 2015 |
Carcinogenesis of urethane: simulation versus experiment.
Topics: Carcinogenesis; Carcinogens; DNA; Hydrolysis; Quantum Theory; Thermodynamics; Urethane | 2015 |
Fulvestrant-mediated inhibition of estrogen receptor signaling slows lung cancer progression.
Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents, Hormonal; Carcinogenesis; Disease Model | 2014 |
A specific nuclear DNA background is required for high frequency lymphoma development in transmitochondrial mice with G13997A mtDNA.
Topics: Adenoma; AMP-Activated Protein Kinases; Animals; Carcinogenesis; Carcinoma, Hepatocellular; Cell Nuc | 2015 |
A Curcumin Derivative That Inhibits Vinyl Carbamate-Induced Lung Carcinogenesis via Activation of the Nrf2 Protective Response.
Topics: Acetone; Animals; Anticarcinogenic Agents; Arsenites; Benzyl Compounds; Carcinogenesis; Cell Line, T | 2015 |
Caryocar brasiliense camb protects against genomic and oxidative damage in urethane-induced lung carcinogenesis.
Topics: Animals; Antioxidants; Carcinogenesis; Carcinogens; Comet Assay; DNA Damage; Ericales; Genome; Immun | 2015 |
NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function.
Topics: Animals; Carcinogenesis; Cell Line, Tumor; Enzyme Stability; Gene Knockout Techniques; Genes, ras; H | 2016 |
Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro.
Topics: Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Deoxyglucose; Disease Models, Animal; Diseas | 2016 |
The Combination of Three Natural Compounds Effectively Prevented Lung Carcinogenesis by Optimal Wound Healing.
Topics: Animals; Apoptosis; Biological Products; Body Weight; Carcinogenesis; Cell Differentiation; Cell Lin | 2015 |
The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Apoptosis; Autophagy; Benzofurans; Capillary Permea | 2016 |
AKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer.
Topics: Animals; Bronchi; Carcinogenesis; Carcinogens; Cell Transformation, Neoplastic; Epithelial Cells; Fe | 2016 |
Intranasal Administration of Type V Collagen Reduces Lung Carcinogenesis through Increasing Endothelial and Epithelial Apoptosis in a Urethane-Induced Lung Tumor Model.
Topics: Administration, Intranasal; Animals; Apoptosis; Carcinogenesis; Collagen Type V; DNA Fragmentation; | 2016 |
Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model.
Topics: Animals; Capsaicin; Carcinogenesis; Catechols; Disease Models, Animal; ErbB Receptors; Fatty Alcohol | 2016 |
The induction of the initiating phase of skin carcinogenesis in the mouse by oral administration of urethane (ethyl carbamate).
Topics: Administration, Oral; Animals; Carcinogenesis; Mice; Neoplasms, Experimental; Urethane | 1956 |
A quantitative study of the systemic initiating action of urethane (ethyl carbamate) in mouse skin carcinogenesis.
Topics: Animals; Carcinogenesis; Mice; Neoplasms, Experimental; Skin Neoplasms; Urethane | 1957 |
Epidermal carcinogenesis in the mouse by intraperitoneally administered urethane followed by repeated applications of croton oil.
Topics: Animals; Carcinogenesis; Carcinogens; Croton Oil; Epidermis; Mice; Neoplasms, Experimental; Skin Neo | 1957 |
[Experimental studies of the diphasic doctrine of cutaneous carcinogenesis in various animal species. I. Effect of urethane (initiating factor) and of croton oil and tween 60 (promoting factors); experiments with rabbits].
Topics: Animals; Carcinogenesis; Croton Oil; Lagomorpha; Neoplasms, Experimental; Polysorbates; Rabbits; Ski | 1957 |
Urethan and leukemogenesis in mice.
Topics: Animals; Carcinogenesis; Leukemia; Leukemia, Experimental; Mice; Urethane | 1958 |
[Effects of urethane on 9, 10-dimethyl-1, 2-benzanthracene carcinogenesis in rats].
Topics: Animals; Anthracenes; Benz(a)Anthracenes; Carcinogenesis; Rats; Urethane | 1959 |
Leukaemogenesis by urethan in new-born Swiss mice.
Topics: Animals; Carcinogenesis; Leukemia; Leukemia, Experimental; Mice; Urethane | 1961 |
Studies on urethan carcinogenesis.
Topics: Carcinogenesis; Carcinogens; Humans; Urethane | 1961 |
Skin initiating action and lung carcinogenesis byderivatives of urethane (ethyl carbamate) and related compounds.
Topics: Animals; Carcinogenesis; Carcinogens; Humans; Lung; Lung Neoplasms; Neoplasms, Experimental; Skin Ne | 1959 |
Failure of the urethane antagonist-lysergic acid-diethylamide (LSD-25)--to inhibit lung carcinogenesis or the initiating phase of skin carcinogenesis in mice.
Topics: Animals; Carcinogenesis; Lung Neoplasms; Lysergic Acid Diethylamide; Mice; Neoplasms, Experimental; | 1959 |
Possible two-stage mechanism in experimental leukemogenesis.
Topics: Animals; Carcinogenesis; Leukemia, Experimental; Mice; Research; Urethane | 1960 |
Failure of bone marrow to interfere with the augmentation of x-ray leukemogenesis by urethan.
Topics: Animals; Bone Marrow; Carcinogenesis; Leukemia; Leukemia, Experimental; Radiation Protection; Uretha | 1961 |
Leukemogenesis by urethan in C57B1 mice bearing isologous tissues from x-irradiated mice.
Topics: Animals; Carcinogenesis; Injections; Leukemia, Experimental; Mice; Radiation Effects; Transplantatio | 1961 |
[The effect of fatty acids on carcinogenesis. IV. On experiments on inhibition of 20-methylcholanthrene, 9-10-dimenthyl-1, 2-methylcholanthrene, 9-10-dimethyl-1,2-benzanthracene and urethane-induced carcinogenesis by means of linolenic acid].
Topics: alpha-Linolenic Acid; Arachidonic Acid; Benz(a)Anthracenes; Carcinogenesis; Fatty Acids; Methylchola | 1961 |
Multipotential carcinogenesis with urethan in the Syrian golden hamster.
Topics: Animals; Carcinogenesis; Cricetinae; Mesocricetus; Urethane | 1961 |
Influence of urethane on subcutaneous carcinogenesis by "Teflon" implants.
Topics: Carcinogenesis; Neoplasms; Plastics; Polytetrafluoroethylene; Prostheses and Implants; Sarcoma; Sarc | 1963 |
Lung carcinogenesis by urethane in newborn, suckling, and adult Swiss mice.
Topics: Animals; Animals, Newborn; Carcinogenesis; Lung Neoplasms; Mice; Urethane | 1962 |
INFLUENCE OF AGE AND ROUTE OF ADMINISTRATION ON LUNG CARCINOGENESIS BY URETHAN IN SWISS MICE.
Topics: Adenoma; Animals; Animals, Newborn; Carcinogenesis; Female; Humans; Lactation; Lung Neoplasms; Mice; | 1963 |
THE MECHANISM OF CARCINOGENESIS IN BREAST TUMOUR DEVELOPMENT IN MICE.
Topics: Animals; Breast Neoplasms; Carcinogenesis; Humans; Mammary Neoplasms, Animal; Mammary Neoplasms, Exp | 1963 |
INFLUENCE OF AGE ON SUSCEPTIBILITY TO LIVER CARCINOGENESIS AND SKIN INITIATING ACTION BY URETHANE IN SWISS MICE.
Topics: Aging; Animals; Animals, Newborn; Carcinogenesis; Carcinoma, Hepatocellular; Croton Oil; Female; Hum | 1963 |
INFLUENCE OF MUTAGENS ON THE INITIATION OF SKIN CARCINOGENESIS.
Topics: 2-Aminopurine; Acridines; Adenine; Carcinogenesis; Carcinogens; Idoxuridine; Lung Neoplasms; Mice; M | 1964 |
CONTRIBUTION OF URETHAN STUDIES TO THE UNDERSTANDING OF CARCINOGENESIS.
Topics: Adenoma; Animals; Carcinogenesis; Carcinogens; Cricetinae; Mammary Neoplasms, Animal; Mammary Neopla | 1964 |
TRENDS IN CARCINOGENESIS BY URETHAN ADMINISTRATION TO NEW-BORN MICE OF DIFFERENT STRAINS.
Topics: Adenoma; Animals; Animals, Newborn; Carcinogenesis; Carcinogens; Carcinoma, Hepatocellular; Genetics | 1964 |
EXPERIMENTAL EPIDERMAL HYPERPLASIA IN MICE: RELATION TO CARCINOGENESIS.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Cantharidin; Carcinogenesis; Carcinogens; Cell Division; | 1964 |
HORMONAL INFLUENCES ON URETHAN CARCINOGENESIS IN C3H/F MICE.
Topics: Adrenal Gland Neoplasms; Androgens; Animals; Animals, Newborn; Carcinogenesis; Carcinogens; Carcinom | 1964 |
[EXPERIMENTAL STUDIES ON SYNCARCINOGENESIS. II. STUDIES ON CARCINOGENESIS IN MICE IN THE SIMULTANEOUS APPLICATION OF URETHANE AND 9,10-DIMETHYL-1,2-BENZANTHRACENE].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Benz(a)Anthracenes; Carcinogenesis; Carcinogens; Mice; Neoplasms; | 1964 |
Chromatographic studies in relation to ethyl carbamate (urethan) carcinogenesis using C14-labeled compounds.
Topics: Animals; Carcinogenesis; Carcinogens; Neoplasms, Experimental; Urethane | 1960 |
A study of the relationship between the rate of ethyl carbamate (urethan) catabolism and urethan carcinogenesis.
Topics: Carcinogenesis; Carcinogens; Humans; Urethane | 1960 |