Page last updated: 2024-11-05

urethane and Adenocarcinoma

urethane has been researched along with Adenocarcinoma in 68 studies

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" In this paper, we extended our work and examined the effects of I3C (70 or 30 micromol/g diet) and MI (56 micromol/g diet) against vinyl carbamate (VC)-induced lung adenocarcinoma by administering the agents from 1 week after the second of two injections of VC until termination of the study at week 18."7.76Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. ( Hecht, SS; Kalscheuer, S; Kassie, F; Ma, L; Matise, I; Melkamu, T; Upadhyaya, P, 2010)
"Urethane-induced lung carcinogenesis led to more M2 macrophage phenotype and increased abnormal angiogenesis concomitant with the upregulation of LC3-B and the downregulation of p62."5.43The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis. ( Cao, N; Du, GJ; Geng, SN; Guo, ZZ; Han, G; Li, GG; Lin, HH; Ma, XF; Meng, MJ; Zheng, YQ, 2016)
" The effects of activating GPER and function of G15 were analyzed in the proliferation of A549 and H1793 cell lines and development of urethane-induced adenocarcinoma."3.91G-Protein-Coupled Estrogen Receptor Antagonist G15 Decreases Estrogen-Induced Development of Non-Small Cell Lung Cancer. ( Fan, S; Fu, X; Liao, Y; Liu, C; Wang, J; Xiong, J; Zhou, S; Zou, M, 2019)
" XPC-/- mice treated with the CS-carcinogen urethane developed lung adenocarcinomas representing progressive stages of tumor development, with lung tumor number increased 17-fold compared with XPC+/+ mice."3.91XPC protects against smoking- and carcinogen-induced lung adenocarcinoma. ( Saliba, J; Sandusky, GE; Sears, CR; Zhou, H, 2019)
" Additionally, in vitro administration of E2 and G1 increased the number of tumor nodules, tumor grade, and tumor index in a urethane-induced adenocarcinoma model."3.81G protein-coupled estrogen receptor (GPER) mediates NSCLC progression induced by 17β-estradiol (E2) and selective agonist G1. ( Fan, S; Jiang, Z; Liao, Y; Liu, C; Tang, H; Wang, J; Xiong, J; Zhou, B; Zhou, S; Zou, M, 2015)
" A mouse model of urethane-induced lung adenocarcinoma was used in the study."3.80Fulvestrant-mediated inhibition of estrogen receptor signaling slows lung cancer progression. ( Chen, G; Fu, S; Liao, Y; Liu, Z; Tang, H; Xu, L; Yu, L; Zhang, C; Zhou, S, 2014)
" In this paper, we extended our work and examined the effects of I3C (70 or 30 micromol/g diet) and MI (56 micromol/g diet) against vinyl carbamate (VC)-induced lung adenocarcinoma by administering the agents from 1 week after the second of two injections of VC until termination of the study at week 18."3.76Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. ( Hecht, SS; Kalscheuer, S; Kassie, F; Ma, L; Matise, I; Melkamu, T; Upadhyaya, P, 2010)
" Lung adenocarcinomas were induced in A/J mice by injection of the carcinogen vinyl carbamate."3.75Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice. ( Liby, K; Ma, T; Risingsong, R; Royce, DB; Sporn, MB; Williams, CR; Yore, MM, 2009)
" Female A/J mice were treated with the mutagenic carcinogen vinyl carbamate, which induces adenocarcinoma of the lung in all animals within 16 weeks."3.74The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice. ( Dmitrovsky, E; Gribble, GW; Honda, T; Liby, K; Risingsong, R; Royce, DB; Sporn, MB; Sporn, TA; Williams, CR; Yore, MM, 2007)
" The goal of this work was to monitor quantitatively the development and progression of adenocarcinoma in a time course study of mice treated with the carcinogen urethane using in vivo small-animal magnetic resonance imaging (MRI)."3.74Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging. ( Garbow, JR; Lubet, RA; Wang, M; Wang, Y; You, M, 2008)
"In the A/J strain of mice, urethane (ethyl carbamate) induces lung hyperplasia, adenoma, and adenocarcinoma in a time-dependent manner."3.69Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice. ( Chen, A; Horio, Y; Malkinson, AM; Rice, P; Roth, JA; Schrump, DS, 1996)
"Urethane-induced lung carcinogenesis led to more M2 macrophage phenotype and increased abnormal angiogenesis concomitant with the upregulation of LC3-B and the downregulation of p62."1.43The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis. ( Cao, N; Du, GJ; Geng, SN; Guo, ZZ; Han, G; Li, GG; Lin, HH; Ma, XF; Meng, MJ; Zheng, YQ, 2016)
"Lung cancer is the leading cause of cancer-related death worldwide."1.38Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice. ( Hayakawa, T; Imai, T; Imaida, K; Komiya, M; Mutoh, M; Takahashi, M; Tsuta, K; Ueno, T; Wakabayashi, K; Yanaka, A; Yoshimoto, M, 2012)
"Lung cancer is one of the most important avoidable causes of death around the world, the most widespread carcinoma, with a very poor prognosis, and is the leading cause of cancer death in both developed and developing countries."1.37Characterization of a murine lung adenocarcinoma (LAC1), a useful experimental model to study progression of lung cancer. ( Díaz, Mdel P; Eynard, AR; Ortiz, S; Piegari, M; Valentich, MA, 2011)
"When pioglitazone was administered beginning 8 weeks after the first carcinogen treatment when microscopic adenomas already existed, pioglitazone significantly inhibited tumor load (sum of tumor volume per lung in average) by 64% (P < 0."1.36Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice. ( James, M; Lu, Y; Lubet, RA; Szabo, E; Wang, Y; Wen, W; You, M, 2010)
"Urethane treatment accelerated number and size of lung tumors developing in SOPten(flox/flox) mice of both ages."1.34Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. ( Hamada, K; Horie, Y; Kawahara, K; Kishimoto, H; Kubo, H; Mak, TW; Nakano, T; Nakazato, M; Nishio, M; Sasaki, M; Sasaki, T; Suzuki, A; Whitsett, JA; Yajima, N; Yanagi, S, 2007)
"Bexarotene (Targretin), is a synthetic high-affinity RXR receptor agonist with limited affinity for RAR receptors."1.33Prevention of lung cancer progression by bexarotene in mouse models. ( Jia, D; Lubet, RA; Wang, D; Wang, Y; Yao, R; You, M; Zhang, Z, 2006)
" Ten weekly ethyl carbamate (EC) doses caused a nearly 100% lung tumor incidence with a tumor multiplicity >2; multiple EC dosing is thus an alternative to the time-consuming transfer of transgenes and null mutations to susceptible backgrounds."1.32Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections. ( Dwyer-Nield, LD; Franklin, WA; Keith, RL; Le, M; Malkinson, AM; Miller, YE, 2003)

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199026 (38.24)18.7374
1990's6 (8.82)18.2507
2000's19 (27.94)29.6817
2010's17 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Liu, C2
Liao, Y3
Fan, S2
Fu, X1
Xiong, J2
Zhou, S3
Zou, M2
Wang, J2
Zhou, H1
Saliba, J1
Sandusky, GE1
Sears, CR1
Satoh, H1
Moriguchi, T1
Takai, J1
Ebina, M2
Yamamoto, M1
Jan Treda, C1
Fukuhara, T1
Suzuki, T1
Nakamura, A1
Zaini, J1
Kikuchi, T1
Nukiwa, T1
Westcott, PM1
Halliwill, KD1
To, MD1
Rashid, M1
Rust, AG1
Keane, TM1
Delrosario, R1
Jen, KY1
Gurley, KE1
Kemp, CJ1
Fredlund, E1
Quigley, DA1
Adams, DJ1
Balmain, A1
Yun, HM1
Park, KR1
Park, MH1
Kim, DH1
Jo, MR1
Kim, JY1
Kim, EC1
Yoon, DY1
Han, SB1
Hong, JT1
Tang, H2
Zhang, C1
Chen, G1
Xu, L1
Liu, Z1
Fu, S1
Yu, L1
Jiang, Z1
Zhou, B1
Tsuji, S1
Kuwahara, Y1
Takagi, H1
Sugiura, M1
Nakanishi, Y1
Wakamatsu, M1
Tsuritani, K1
Sato, Y1
Li, GG1
Guo, ZZ1
Ma, XF1
Cao, N1
Geng, SN1
Zheng, YQ1
Meng, MJ1
Lin, HH1
Han, G1
Du, GJ1
Kassie, F2
Kalscheuer, S1
Matise, I1
Ma, L1
Melkamu, T2
Upadhyaya, P1
Hecht, SS1
Herzog, CR3
Blake, DC1
Mikse, OR1
Grigoryeva, LS1
Gundermann, EL1
Zhang, X1
Tan, J1
Zeng, Y1
Liby, K2
Risingsong, R2
Royce, DB2
Williams, CR2
Ma, T1
Yore, MM2
Sporn, MB2
Lee, KS1
Lee, YS1
Lee, JM1
Ito, K1
Cinghu, S1
Kim, JH1
Jang, JW1
Li, YH1
Goh, YM1
Chi, XZ1
Wee, H1
Lee, HW1
Hosoya, A1
Chung, JH1
Jang, JJ1
Kundu, JK1
Surh, YJ1
Kim, WJ1
Ito, Y1
Jung, HS1
Bae, SC1
Karoor, V1
Le, M2
Merrick, D1
Dempsey, EC1
Miller, YE2
Wang, Y4
James, M1
Wen, W1
Lu, Y1
Szabo, E2
Lubet, RA6
You, M6
Piegari, M2
Ortiz, S1
Díaz, Mdel P1
Eynard, AR2
Valentich, MA2
Ueno, T1
Imaida, K1
Yoshimoto, M1
Hayakawa, T1
Takahashi, M1
Imai, T1
Yanaka, A1
Tsuta, K1
Komiya, M1
Wakabayashi, K1
Mutoh, M1
Pereira, MA2
Li, Y1
Gunning, WT2
Kramer, PM2
Al-Yaqoub, F1
Steele, VE2
Tao, L1
Kang, Y1
Ozbun, LL1
Angdisen, J1
Moody, TW1
Prentice, M1
Diwan, BA1
Jakowlew, SB2
Devereux, TR2
Pittman, B2
Dwyer-Nield, LD2
Keith, RL1
Franklin, WA1
Malkinson, AM5
ELION, GB1
BIEBER, S1
HITCHINGS, GH1
SCHOENTAL, R2
Zhang, F1
Pao, W1
Umphress, SM1
Meyer, AM1
Nielsen, LD1
Takeda, K1
Gelfand, EW1
Fisher, JH1
Zhang, L1
Mason, RJ1
Bodon, N1
Maronpot, RR1
Massey, TE1
Anderson, MW1
Ozaki, M1
Ozaki, K1
Watanabe, T1
Uwagawa, S1
Okuno, Y1
Shirai, T2
Zhang, Z2
Yao, R1
Jia, D1
Wang, D1
Kim, IM1
Ackerson, T1
Ramakrishna, S1
Tretiakova, M1
Wang, IC1
Kalin, TV1
Major, ML1
Gusarova, GA1
Yoder, HM1
Costa, RH1
Kalinichenko, VV1
Redente, EF1
Orlicky, DJ1
Bouchard, RJ1
Honda, T1
Gribble, GW1
Dmitrovsky, E1
Sporn, TA1
Yanagi, S1
Kishimoto, H1
Kawahara, K1
Sasaki, T1
Sasaki, M1
Nishio, M1
Yajima, N1
Hamada, K1
Horie, Y1
Kubo, H1
Whitsett, JA1
Mak, TW1
Nakano, T1
Nakazato, M1
Suzuki, A1
Garbow, JR1
Wang, M1
Masuda, A1
Hirose, M1
Ikawa, E1
Ito, N1
Imai, S1
Morimoto, J1
Tsubura, Y1
Hilgers, J1
Hirono, I1
Hosaka, S1
Kuhara, K1
Kawano, R1
Nishisaka, T1
Takeshima, Y1
Yonehara, S1
Inai, K1
Horio, Y1
Chen, A1
Rice, P1
Roth, JA1
Schrump, DS1
Mohr, U1
Dasenbrock, C1
Tillmann, T1
Kohler, M1
Kamino, K1
Hagemann, G1
Morawietz, G1
Campo, E1
Cazorla, M1
Fernandez, P1
Hernandez, L1
Cardesa, A1
Tomatis, L1
Hiai, H1
Abujiang, P1
Nishimura, M1
Salvador, AF1
Muñoz, SE1
Kawai, T1
Matsuzawa, A1
Yamamoto, T1
Mizuno, Y1
Sonntag, AC1
Medina, D2
Warner, MR1
Goldfeder, A1
Bhide, SV1
Sirsat, MV1
Anisimov, VN1
Pan, YH1
Nuzum, EO2
Hanson, LA1
Beer, DG2
Parsons, DF1
Foley, J1
Marko, M1
Wansor, K1
Yamamoto, H1
Fujishiro, K1
Yamamoto, I1
Vesselinovitch, SD1
Mihailovich, N1
Pietra, G1
Nomura, T1
Okada, Y1
Krakoff, IH1
Clifford, GO1
Cioli, V1
Scorza Barcellona, P1
Silvestrini, B1
Shabad, LM1
Toth, B2
Bensted, JP1
Smithers, D1
Bennett, LL1
Struck, RF1

Reviews

4 reviews available for urethane and Adenocarcinoma

ArticleYear
Polygenic resistance to mouse pulmonary adenomas.
    Experimental lung research, 2000, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Chromosomes, Huma

2000
Xenobiotics and molecular teratology.
    Clinical obstetrics and gynecology, 1975, Volume: 18, Issue:4

    Topics: Abnormalities, Drug-Induced; Adenocarcinoma; Animals; Carcinogens; Diethylstilbestrol; Drug Interact

1975
More about isonicotinic acid hydrazide toxicity.
    Food and cosmetics toxicology, 1970, Volume: 8, Issue:5

    Topics: Adenocarcinoma; Adenofibroma; Adenoma; Animals; Carcinoma; Chemical and Drug Induced Liver Injury; C

1970
Further chapters in the hydrazine story.
    Food and cosmetics toxicology, 1971, Volume: 9, Issue:5

    Topics: Adenocarcinoma; Anemia, Hemolytic; Animals; Carbon Isotopes; Carcinogens; Colonic Neoplasms; Criceti

1971

Trials

1 trial available for urethane and Adenocarcinoma

ArticleYear
Clinical studies of n-hydroxyurethan (NSC-83629).
    Cancer chemotherapy reports, 1968, Volume: 52, Issue:6

    Topics: Adenocarcinoma; Adult; Antineoplastic Agents; Clinical Trials as Topic; Female; Humans; Male; Melano

1968

Other Studies

63 other studies available for urethane and Adenocarcinoma

ArticleYear
G-Protein-Coupled Estrogen Receptor Antagonist G15 Decreases Estrogen-Induced Development of Non-Small Cell Lung Cancer.
    Oncology research, 2019, Feb-21, Volume: 27, Issue:3

    Topics: A549 Cells; Adenocarcinoma; Animals; Benzodioxoles; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor

2019
XPC protects against smoking- and carcinogen-induced lung adenocarcinoma.
    Carcinogenesis, 2019, 05-14, Volume: 40, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinogens; Cigarette Smoking; DNA Damage; Female; Humans; Lung Neoplasms;

2019
Nrf2 prevents initiation but accelerates progression through the Kras signaling pathway during lung carcinogenesis.
    Cancer research, 2013, Jul-01, Volume: 73, Issue:13

    Topics: Adenocarcinoma; Animals; Base Sequence; Cell Transformation, Neoplastic; Cytochrome P-450 CYP2E1; DN

2013
Secretory leukocyte protease inhibitor modulates urethane-induced lung carcinogenesis.
    Carcinogenesis, 2014, Volume: 35, Issue:4

    Topics: Adenocarcinoma; Animals; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; DNA Pr

2014
The mutational landscapes of genetic and chemical models of Kras-driven lung cancer.
    Nature, 2015, Jan-22, Volume: 517, Issue:7535

    Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Transformation, Neoplasti

2015
PRDX6 promotes tumor development via the JAK2/STAT3 pathway in a urethane-induced lung tumor model.
    Free radical biology & medicine, 2015, Volume: 80

    Topics: Adenocarcinoma; Animals; Chemokine CCL5; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Glut

2015
Fulvestrant-mediated inhibition of estrogen receptor signaling slows lung cancer progression.
    Oncology research, 2014, Volume: 22, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents, Hormonal; Carcinogenesis; Disease Model

2014
G protein-coupled estrogen receptor (GPER) mediates NSCLC progression induced by 17β-estradiol (E2) and selective agonist G1.
    Medical oncology (Northwood, London, England), 2015, Volume: 32, Issue:4

    Topics: Adenocarcinoma; Aged; Animals; Apoptosis; Blotting, Western; Carcinogens; Carcinoma, Non-Small-Cell

2015
Gene expression analysis in the lung of the rasH2 transgenic mouse at week 4 prior to induction of malignant tumor formation by urethane and N-methylolacrylamide.
    The Journal of toxicological sciences, 2015, Volume: 40, Issue:6

    Topics: Acrylamides; Adenocarcinoma; Adenoma; Animals; Aurora Kinase B; Biomarkers, Tumor; Carcinoembryonic

2015
The M2 macrophages induce autophagic vascular disorder and promote mouse sensitivity to urethane-related lung carcinogenesis.
    Developmental and comparative immunology, 2016, Volume: 59

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Apoptosis; Autophagy; Benzofurans; Capillary Permea

2016
Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice.
    Carcinogenesis, 2010, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Prol

2010
FoxO3a gene is a target of deletion in mouse lung adenocarcinoma.
    Oncology reports, 2009, Volume: 22, Issue:4

    Topics: Adenocarcinoma; Aflatoxin B1; Animals; Carcinogens; Disease Models, Animal; Forkhead Box Protein O3;

2009
Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol.
    Carcinogenesis, 2010, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Blotting, Western; Female; Gene Expression Profili

2010
Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice.
    Cancer prevention research (Philadelphia, Pa.), 2009, Volume: 2, Issue:12

    Topics: Adenocarcinoma; Animals; Cell Proliferation; Fatty Acids, Unsaturated; Female; Ligands; Lung Neoplas

2009
Runx3 is required for the differentiation of lung epithelial cells and suppression of lung cancer.
    Oncogene, 2010, Jun-10, Volume: 29, Issue:23

    Topics: Adenocarcinoma; Animals; Cell Differentiation; Cell Proliferation; Core Binding Factor Alpha 3 Subun

2010
Vascular endothelial growth factor receptor 2-targeted chemoprevention of murine lung tumors.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:9

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Carc

2010
Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:11

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carcinogens; Carcinoma, Squamous Cell; Chemopreventi

2010
Characterization of a murine lung adenocarcinoma (LAC1), a useful experimental model to study progression of lung cancer.
    Journal of experimental therapeutics & oncology, 2011, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Animals; Cell Proliferation; Cells, Cultured; Concanavalin A; Erythrocyte Count; Hem

2011
Non-invasive X-ray micro-computed tomographic evaluation of indomethacin on urethane-induced lung carcinogenesis in mice.
    Anticancer research, 2012, Volume: 32, Issue:11

    Topics: Adenocarcinoma; Adenoma; Animals; Antineoplastic Agents; Carcinogens; Humans; Hyperplasia; Immunohis

2012
Prevention of mouse lung tumors by budesonide and its modulation of biomarkers.
    Carcinogenesis, 2002, Volume: 23, Issue:7

    Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Biomarkers, Tumor; Budesonide; Cell Divis

2002
Altered expression of G1/S regulatory genes occurs early and frequently in lung carcinogenesis in transforming growth factor-beta1 heterozygous mice.
    Carcinogenesis, 2002, Volume: 23, Issue:7

    Topics: Adenocarcinoma; Animals; Cell Cycle Proteins; Cell Division; DNA Primers; Female; G1 Phase; Gene Exp

2002
Carcinogenic induction directs the selection of allelic losses in mouse lung tumorigenesis.
    Cancer research, 2002, Nov-15, Volume: 62, Issue:22

    Topics: Adenocarcinoma; Animals; Carcinogens; Loss of Heterozygosity; Lung Neoplasms; Mice; Mice, Inbred A;

2002
Induction of a high incidence of lung tumors in C57BL/6 mice with multiple ethyl carbamate injections.
    Cancer letters, 2003, Aug-20, Volume: 198, Issue:2

    Topics: Adenocarcinoma; Animals; Butylated Hydroxytoluene; Carcinogens; Disease Models, Animal; Incidence; L

2003
Studies on the mechanism of action of urethane on mammary adenocarcinoma 755.
    Acta - Unio Internationalis Contra Cancrum, 1960, Volume: 16

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Humans; Mammary Neoplasms, Experimental; Urethane

1960
INDUCTION OF TUMOURS OF THE STOMACH IN RATS AND MICE BY N-NITROSO-NALKYLURETHANES.
    Nature, 1963, Jul-13, Volume: 199

    Topics: Adenocarcinoma; Animals; Carcinogens; Carcinoma; Carcinoma, Squamous Cell; Mice; Neoplasms, Experime

1963
Serum levels of surfactant protein D are increased in mice with lung tumors.
    Cancer research, 2003, Sep-15, Volume: 63, Issue:18

    Topics: Adenocarcinoma; Animals; Carcinogens; Gene Deletion; Gene Expression Regulation, Neoplastic; Genes,

2003
Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression.
    Oncogene, 2004, Apr-15, Volume: 23, Issue:17

    Topics: Adenocarcinoma; Animals; Carcinogens; Chromosomal Instability; Chromosome Deletion; Chromosome Mappi

2004
Susceptibilities of p53 knockout and rasH2 transgenic mice to urethane-induced lung carcinogenesis are inherited from their original strains.
    Toxicologic pathology, 2005, Volume: 33, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Body Weight; Disease Models, Animal; Genes, p53; Genes, ras; Genet

2005
A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice.
    Oncogene, 2006, Feb-23, Volume: 25, Issue:8

    Topics: Adenocarcinoma; Animals; Cocarcinogenesis; Disease Models, Animal; Disease Progression; Genes, ras;

2006
Prevention of lung cancer progression by bexarotene in mouse models.
    Oncogene, 2006, Mar-02, Volume: 25, Issue:9

    Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Bexarotene; Carcinogens; Carcinoma, Non-S

2006
The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer.
    Cancer research, 2006, Feb-15, Volume: 66, Issue:4

    Topics: Adenocarcinoma; Alleles; Animals; Carcinoma, Non-Small-Cell Lung; Cell Adhesion; Cell Growth Process

2006
Tumor signaling to the bone marrow changes the phenotype of monocytes and pulmonary macrophages during urethane-induced primary lung tumorigenesis in A/J mice.
    The American journal of pathology, 2007, Volume: 170, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Biomarkers, Tumor; Bone Marrow; Carcinogens; Cell Transformation,

2007
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.
    Cancer research, 2007, Mar-15, Volume: 67, Issue:6

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Cell Line, Tumor; Humans; Lung; Lung Ne

2007
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:10

    Topics: Adenocarcinoma; Animals; Bronchi; Cell Transformation, Neoplastic; Gene Expression; Lung; Lung Neopl

2007
Quantitative monitoring of adenocarcinoma development in rodents by magnetic resonance imaging.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Mar-01, Volume: 14, Issue:5

    Topics: Adenocarcinoma; Animals; Carcinogens; Disease Models, Animal; Image Interpretation, Computer-Assiste

2008
Enhancement of N-bis(2-hydroxypropyl)nitrosamine-initiated lung tumor development in rats by bleomycin and N-methyl-N-nitrosourethane.
    Cancer letters, 1984, Volume: 25, Issue:1

    Topics: Adenocarcinoma; Animals; Bleomycin; Carcinogens; Drug Synergism; Hyperplasia; Lung; Lung Neoplasms;

1984
Mammary tumor induction in inbred mouse strains with urethane is not accompanied by changes in expression of B- and C-type retroviral structural proteins.
    International journal of cancer, 1982, Jul-15, Volume: 30, Issue:1

    Topics: Adenocarcinoma; Animals; Antigens, Viral; Disease Susceptibility; Female; Gammaretrovirus; Leukemia

1982
Enhancement by bracken of induction of tumours of the upper alimentary tract by N-propyl-N-nitrosourethan.
    British journal of cancer, 1982, Volume: 46, Issue:3

    Topics: Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Esophageal Neoplasms; Female; Gastrointestinal Ne

1982
Role of point mutation of the K-ras gene in tumorigenesis of B6C3F1 mouse lung lesions induced by urethane.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:9

    Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Disease Models, Animal; Dose-Response Relationship,

1995
Ki-ras and p53 mutations are early and late events, respectively, in urethane-induced pulmonary carcinogenesis in A/J mice.
    Molecular carcinogenesis, 1996, Volume: 17, Issue:4

    Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Carcinogens; Disease Progression; Exons; Genes, p53

1996
Possible carcinogenic effects of X-rays in a transgenerational study with CBA mice.
    Carcinogenesis, 1999, Volume: 20, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cocarcinogenesis; Female; Genes, ras; Hematologic Neo

1999
Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice.
    Experimental lung research, 2000, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Dexamethaso

2000
Delayed-type hypersensitivity and humoral immunity modulation by dietary lipids in a murine model of pulmonary tumorigenesis induced by urethan.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2001, Volume: 53, Issue:2-3

    Topics: Adenocarcinoma; Animals; Antibody Formation; Carcinogens; Dietary Fats, Unsaturated; Disease Models,

2001
Histopathological studies on experimentally induced pulmonary, pleural and peritoneal neoplasms in mice by intraperitoneal injection of chrysotile asbestos and N-methyl-N-nitrosourethane.
    Acta pathologica japonica, 1979, Volume: 29, Issue:3

    Topics: Adenocarcinoma; Animals; Asbestos; Female; Injections, Intraperitoneal; Lung Neoplasms; Male; Mice;

1979
An ovary-dependent mouse mammary tumor induced by urethan.
    Gan, 1977, Volume: 68, Issue:4

    Topics: Adenocarcinoma; Animals; Estrogens; Female; Male; Mammary Neoplasms, Experimental; Mice; Neoplasms,

1977
Mammary tumorigenesis in chemical carcinogen-treated mice. IV. Induction of mammary ductal hyperplasias.
    Journal of the National Cancer Institute, 1976, Volume: 57, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Age Factors; Animals; Female; Hyperplasia; Mammary

1976
Induction of type B virions to bud into cytoplasmic vacuoles in a mammary tumor of an X-ray- and urethan-treated X/Gf mouse.
    Cancer research, 1976, Volume: 36, Issue:11 Pt 1

    Topics: Adenocarcinoma; Animals; Cell Membrane; Cytoplasm; Mammary Neoplasms, Experimental; Mice; Mice, Inbr

1976
Biological studies on the effect of DNA extracted from urethan treated mice.
    Indian journal of cancer, 1975, Volume: 12, Issue:2

    Topics: Adenocarcinoma; Animals; Animals, Newborn; DNA; Embryo, Mammalian; Fatty Liver; Female; Lung Neoplas

1975
Two-step carcinogenesis induced by neonatal exposure to 5-bromo-2'- deoxyuridine and subsequent administration of urethan in BALB/c mice.
    Cancer letters, 1992, May-30, Volume: 64, Issue:1

    Topics: Adenocarcinoma; Adenoma; Animals; Animals, Newborn; Body Weight; Bromodeoxyuridine; Cocarcinogenesis

1992
Ki-ras activation and expression in transformed mouse lung cell lines.
    Molecular carcinogenesis, 1990, Volume: 3, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Base Sequence; Cell Division; Cell Transformation, Neoplastic; Gen

1990
Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas.
    Molecular carcinogenesis, 1990, Volume: 3, Issue:5

    Topics: Adenocarcinoma; Adenoma; Animals; Codon; Gene Expression; Lung Neoplasms; Mice; Mice, Inbred A; Muta

1990
Immediate ascites conversion of mammary tumors induced in NYLR/Nya mice by 7,12-dimethylbenz-[a] anthracene and urethane feeding and by forced breeding.
    Cancer investigation, 1986, Volume: 4, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Ascites; Breeding; Carcinoma; Cell Divisi

1986
The changes of glycosaminoglycan in the growth of urethane-induced mouse mammary tumors.
    The Kitasato archives of experimental medicine, 1989, Volume: 62, Issue:1

    Topics: Adenocarcinoma; Animals; Female; Glycosaminoglycans; Mammary Neoplasms, Experimental; Mice; Mice, In

1989
The prenatal exposure of mice to urethan and the consequent development of tumors in various tissues.
    Cancer research, 1967, Volume: 27, Issue:12

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma, Hepatocellular; Female; Liver Neoplasms; L

1967
Sensitivity of a lung cell in the developing mouse embryo to tumor induction by urethan.
    Cancer research, 1974, Volume: 34, Issue:12

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cell Differentiation; Dose-Response Relationship, Dru

1974
Electron microscopic study of interstitial pneumonia, with special reference to alveolar epithelial cells.
    Acta pathologica japonica, 1972, Volume: 22, Issue:4

    Topics: Adenocarcinoma; Adenoma; Adult; Aged; Amphibians; Animals; Biopsy; Birds; Epithelium; Female; Humans

1972
Mammary tumorigenesis in chemical carcinogen-treated mice. I. Incidence in BALB-c and C57BL mice.
    Journal of the National Cancer Institute, 1974, Volume: 53, Issue:1

    Topics: Adenocarcinoma; Animals; Benz(a)Anthracenes; Carcinogens; Hyperplasia; Mammary Neoplasms, Experiment

1974
Study of the potential carcinogenicity of topical drug. Suggestions for a new experimental approach.
    Experimental and molecular pathology, 1971, Volume: 15, Issue:1

    Topics: Adenocarcinoma; Administration, Topical; Animals; Anti-Inflammatory Agents; Bronchial Neoplasms; Car

1971
Dose-response studies in experimentally induced lung tumours.
    Environmental research, 1971, Volume: 4, Issue:4

    Topics: Adenocarcinoma; Adenoma; Air Pollution; Animals; Benz(a)Anthracenes; Benzopyrenes; Carcinogens; Carc

1971
Susceptibility of guinea pigs to chemical carcinogens: 7,12-Dimethylbenz(a)anthracene and urethan.
    Cancer research, 1970, Volume: 30, Issue:10

    Topics: Adenocarcinoma; Age Factors; Animals; Animals, Newborn; Benz(a)Anthracenes; Female; Guinea Pigs; Inj

1970
Tumor induction by repeated injections of urethan in newborn and adult hamsters: age influence. II.
    Journal of the National Cancer Institute, 1971, Volume: 46, Issue:1

    Topics: Adenocarcinoma; Adenoma; Age Factors; Animals; Animals, Newborn; Cecal Neoplasms; Colonic Neoplasms;

1971
Tumours of the intestines induced in rats by intraperitoneal injections of N-methyl- and N-ethyl-N-nitrosourethanes.
    British journal of cancer, 1968, Volume: 22, Issue:2

    Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Female; Injections, Intraperitoneal; Intestinal Neopl

1968
Inhibiton of protein synthesis in mammalian cells by actinobolin.
    Molecular pharmacology, 1969, Volume: 5, Issue:5

    Topics: Adenocarcinoma; Animals; Anti-Bacterial Agents; Carbon Isotopes; Cell Line; Cell-Free System; Cultur

1969