urea has been researched along with Xeroderma in 40 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Optimization of a topical formula of N-acetylcysteine and urea for the topical treatment of ichthyosis." | 9.22 | Development of a carbocysteine 10% + urea 5% cream for the topical treatment of congenital ichthyosis. ( Batalla-Cebey, A; Crespo-Diz, C; Dávila-Pousa, MC; González-Freire, L, 2022) |
| "The analysis of the global estimation of severity of ichthyosis showed improvements being stronger in the body areas treated with Laceran 10% urea lotion (from 4." | 9.08 | Efficacy of urea therapy in children with ichthyosis. A multicenter randomized, placebo-controlled, double-blind, semilateral study. ( Bohnsack, K; Groll, S; Küster, W; Rippke, F; Traupe, H; Upmeyer, HJ, 1998) |
| "N-acetylcysteine in combination with urea is effective for the treatment of congenital ichthyosis." | 7.88 | Topical carbocysteine: A new option for the treatment of ichthyosis. ( Batalla, A; Dávila-Pousa, C; Feal, C; Flórez, Á, 2018) |
| "Optimization of a topical formula of N-acetylcysteine and urea for the topical treatment of ichthyosis." | 5.22 | Development of a carbocysteine 10% + urea 5% cream for the topical treatment of congenital ichthyosis. ( Batalla-Cebey, A; Crespo-Diz, C; Dávila-Pousa, MC; González-Freire, L, 2022) |
| "The analysis of the global estimation of severity of ichthyosis showed improvements being stronger in the body areas treated with Laceran 10% urea lotion (from 4." | 5.08 | Efficacy of urea therapy in children with ichthyosis. A multicenter randomized, placebo-controlled, double-blind, semilateral study. ( Bohnsack, K; Groll, S; Küster, W; Rippke, F; Traupe, H; Upmeyer, HJ, 1998) |
| "N-acetylcysteine in combination with urea is effective for the treatment of congenital ichthyosis." | 3.88 | Topical carbocysteine: A new option for the treatment of ichthyosis. ( Batalla, A; Dávila-Pousa, C; Feal, C; Flórez, Á, 2018) |
| "Preparations containing urea were found to be effective in the treatment of ichthyosis vulgaris and so we were encouraged to test their use in other dry skin conditions." | 3.67 | [Urea as a single drug in dry skin]. ( Swanbeck, G, 1989) |
| "The uremic pruritus is a very painful symptom suffered by chronic haemodialysis patients and is observed in 22 to 74% of the subjects." | 2.45 | [Pruritus and dryness of the skin in chronic kidney insufficiency and dialysis patients - a review]. ( Durrant-Finn, U; Mügge, C; Nenoff, P; Osten, B, 2009) |
| "Urea is a major component of many daily skincare products which is widely used." | 1.56 | Mode of action of urea. ( Dirschka, T, 2020) |
| "Urea has anti-inflammatory, hyposensitizing, and antioxidant effect." | 1.36 | [The evaluation of nitrogen metabolism and the reactivity of the organism in patients with dry skin]. ( Katsitadze, AG; Tsiskarishvili, NI; Tsiskarishvili, NV, 2010) |
| "Salicylic acid ointment was applied on one and carbamide ointment on the other back of the hand." | 1.28 | [Water content of the skin following salicylic acid and urea treatment]. ( Jakab, E; Rácz, I; Soós, G, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (67.50) | 18.7374 |
| 1990's | 1 (2.50) | 18.2507 |
| 2000's | 4 (10.00) | 29.6817 |
| 2010's | 5 (12.50) | 24.3611 |
| 2020's | 3 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| González-Freire, L | 1 |
| Dávila-Pousa, MC | 1 |
| Batalla-Cebey, A | 1 |
| Crespo-Diz, C | 1 |
| Verzì, AE | 1 |
| Musumeci, ML | 1 |
| Lacarrubba, F | 1 |
| Micali, G | 1 |
| Dirschka, T | 1 |
| Batalla, A | 1 |
| Dávila-Pousa, C | 1 |
| Feal, C | 1 |
| Flórez, Á | 1 |
| Lindh, JD | 1 |
| Bradley, M | 1 |
| Danby, SG | 1 |
| Brown, K | 1 |
| Higgs-Bayliss, T | 1 |
| Chittock, J | 1 |
| Albenali, L | 1 |
| Cork, MJ | 1 |
| Faergemann, J | 1 |
| Olsson, P | 1 |
| Svensson, A | 1 |
| Durrant-Finn, U | 1 |
| Osten, B | 1 |
| Mügge, C | 1 |
| Nenoff, P | 2 |
| Tsiskarishvili, NV | 1 |
| Katsitadze, AG | 1 |
| Tsiskarishvili, NI | 1 |
| Machan, M | 1 |
| Kestenbaum, T | 1 |
| Fraga, GR | 1 |
| Donaubauer, K | 1 |
| Arndt, T | 1 |
| Haustein, UF | 1 |
| Gilardi, S | 1 |
| Schibli, H | 1 |
| Grekin, JL | 1 |
| Basler, RS | 1 |
| Küster, W | 1 |
| Bohnsack, K | 1 |
| Rippke, F | 1 |
| Upmeyer, HJ | 1 |
| Groll, S | 1 |
| Traupe, H | 1 |
| Ademola, J | 1 |
| Frazier, C | 1 |
| Kim, SJ | 1 |
| Theaux, C | 1 |
| Saudez, X | 1 |
| Fisher, AA | 1 |
| Blair, C | 1 |
| Horii, I | 1 |
| Nakayama, Y | 1 |
| Obata, M | 1 |
| Tagami, H | 1 |
| Schnyder, UW | 1 |
| Swanbeck, G | 3 |
| Rácz, I | 1 |
| Soós, G | 1 |
| Jakab, E | 1 |
| Wohlrab, W | 1 |
| Taube, KM | 1 |
| Vol'rab, V | 1 |
| Vozniak, KD | 1 |
| Beverley, DW | 1 |
| Wheeler, D | 1 |
| Garty, BZ | 1 |
| Grice, K | 1 |
| Sattar, H | 1 |
| Baker, H | 1 |
| Zuehlke, RL | 1 |
| Pope, FM | 1 |
| Rees, JK | 1 |
| Wells, RS | 1 |
| Lewis, KG | 1 |
| Jacoby, RH | 1 |
| Gilkes, JJ | 1 |
| Almeyda, J | 1 |
| Fry, L | 1 |
| Hindson, TC | 1 |
| Nash, DP | 1 |
| Solente, G | 1 |
| Ashton, H | 1 |
| Frenk, E | 1 |
| Stevenson, CJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Skin Pathology Assessment With Optical Technologies (SPOT): a Cross- Sectional Clinical Study in Atopic Dermatitis Patients and Healthy Subjects[NCT04295824] | 80 participants (Anticipated) | Observational | 2020-08-06 | Recruiting | |||
| Validation of a Novel Composite of Skin Biomarkers as a Primary Outcome Measure for Evaluating the Safety of Treatments for Atopic Dermatitis: a Randomized Controlled Trial (Phase 2) Comparing the Effects of Crisaborole 2% Ointment to Betamethasone Valera[NCT04194814] | Phase 2 | 37 participants (Actual) | Interventional | 2020-11-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for urea and Xeroderma
| Article | Year |
|---|---|
Development of a carbocysteine 10% + urea 5% cream for the topical treatment of congenital ichthyosis.
Topics: Administration, Topical; Carbocysteine; Humans; Ichthyosis; Ichthyosis, Lamellar; Urea | 2022 |
Clinical Effectiveness of Moisturizers in Atopic Dermatitis and Related Disorders: A Systematic Review.
Topics: Dermatitis, Atopic; Dermatitis, Irritant; Emollients; Epidermis; Glycerol; Hand Dermatoses; Humans; | 2015 |
[Pruritus and dryness of the skin in chronic kidney insufficiency and dialysis patients - a review].
Topics: Antipruritics; Arginine; Calcineurin Inhibitors; Capsaicin; Controlled Clinical Trials as Topic; Hum | 2009 |
[Urea and urea combinations in ichthyoses].
Topics: Administration, Topical; Dermatologic Agents; Drug Therapy, Combination; Humans; Ichthyosis; Urea | 1989 |
[Therapy of "dry skin" with creams containing urea].
Topics: Humans; Ichthyosis; Ointments; Skin; Urea; Water-Electrolyte Balance | 1988 |
10 trials available for urea and Xeroderma
| Article | Year |
|---|---|
A randomized, single-blind comparison of the efficacy, tolerability and cosmetic acceptance of Propyless or Fenuril treatment of patients with dry skin.
Topics: Administration, Topical; Adult; Aged; Emollients; Esthetics; Female; Humans; Ichthyosis; Leg; Male; | 2009 |
[Topically applied arginine hydrochloride. Effect on urea content of stratum corneum and skin hydration in atopic eczema and skin aging].
Topics: Administration, Topical; Adult; Aged; Arginine; Biopsy; Dermatitis, Atopic; Epidermis; Female; Human | 2004 |
Efficacy of urea therapy in children with ichthyosis. A multicenter randomized, placebo-controlled, double-blind, semilateral study.
Topics: Adolescent; Child; Child, Preschool; Dermatitis, Contact; Dermatitis, Irritant; Double-Blind Method; | 1998 |
Clinical evaluation of 40% urea and 12% ammonium lactate in the treatment of xerosis.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Double-Blind Method; Drug Administration Schedul | 2002 |
The action of a urea-lactic acid ointment in ichthyosis with particular reference to the thickness of the horny layer.
Topics: Adolescent; Adult; Aged; Female; Humans; Ichthyosis; Lactates; Male; Middle Aged; Ointment Bases; Ps | 1976 |
Urea and retinoic acid in ichthyosis and their effect on transepidermal water loss and water holding capacity of stratum corneum.
Topics: Adolescent; Adult; Child; Chromosome Aberrations; Chromosome Disorders; Female; Humans; Ichthyosis; | 1973 |
Out-patient treatment of ichthyosis: a double-blind trial of ointments.
Topics: Attitude to Health; Clinical Trials as Topic; Dermatologic Agents; Emulsions; Humans; Ichthyosis; Oi | 1972 |
Carbamide in hyperkeratosis.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Dermatitis, Atopic; Eval | 1973 |
A new urea/hydrocortisone powder-cream compared with other topical corticosteroid preparations: a six-centre study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Betamethasone; Child; Ch | 1974 |
Controlled trial of the treatment of atopic eczema with a urea-hydrocortisone preparation versus betamethasone 17-valerat.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Betamethasone; Child; Ch | 1973 |
25 other studies available for urea and Xeroderma
| Article | Year |
|---|---|
History of urea as a dermatological agent in clinical practice.
Topics: Dermatitis, Atopic; Dermatologic Agents; Eczema; Humans; Ichthyosis; Urea | 2020 |
Mode of action of urea.
Topics: Dermatitis, Atopic; Humans; Ichthyosis; Psoriasis; Skin; Urea | 2020 |
Topical carbocysteine: A new option for the treatment of ichthyosis.
Topics: Administration, Topical; Anti-Infective Agents, Local; Carbocysteine; Child; Child, Preschool; Drug | 2018 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
[The evaluation of nitrogen metabolism and the reactivity of the organism in patients with dry skin].
Topics: Adolescent; Adult; Dermatitis, Atopic; Desiccation; Filaggrin Proteins; Humans; Ichthyosis; Immunogl | 2010 |
Diffuse hyperkeratosis in a deaf and blind 48-year-old woman--quiz case. Diagnosis: keratitis-ichthyosis-deafness (KID) syndrome with secondary dermatophytosis.
Topics: Antifungal Agents; Baths; Blindness; Deafness; Dermatologic Agents; Female; Fluconazole; Humans; Ich | 2012 |
[Therapeutic possibilities in ichthyosis and ichthyosiforme states].
Topics: Adolescent; Child; Child, Preschool; Etretinate; Female; Humans; Ichthyosis; Male; Urea | 1982 |
New treatments for ichthyosis.
Topics: Humans; Hydroxy Acids; Ichthyosis; Petrolatum; Propylene Glycols; Salicylates; Skin; Urea; Vitamin A | 1980 |
Irritant reactions from topical urea preparations used for dry skin. Advantages of a urea-free "Dead Sea salt" cream.
Topics: Administration, Topical; Drug Eruptions; Humans; Ichthyosis; Ointments; Patch Tests; Skin Diseases; | 1976 |
Stratum corneum hydration and amino acid content in xerotic skin.
Topics: Aged; Aged, 80 and over; Amino Acids; Body Water; Epidermis; Galvanic Skin Response; Humans; Ichthyo | 1989 |
[Urea as a single drug in dry skin].
Topics: Administration, Topical; Dermatologic Agents; Drug Therapy, Combination; Eczema; Hand Dermatoses; Hu | 1989 |
[Water content of the skin following salicylic acid and urea treatment].
Topics: Administration, Topical; Adult; Body Water; Dermatologic Agents; Female; Hand Dermatoses; Humans; Ic | 1989 |
[Use of a urea emulsion in the treatment of dry skin].
Topics: Administration, Topical; Emulsions; Humans; Ichthyosis; Urea | 1986 |
High plasma urea concentrations in collodion babies.
Topics: Betaine; Drug Combinations; Female; Humans; Ichthyosis; Infant, Newborn; Lactates; Lactic Acid; Skin | 1986 |
High plasma urea concentration in babies with lamellar ichthyosis.
Topics: Drug Combinations; Humans; Ichthyosis; Infant; Infant, Newborn; Lactates; Lactic Acid; Skin Absorpti | 1986 |
High plasma urea concentrations in collodion babies.
Topics: Dermatologic Agents; Humans; Ichthyosis; Infant, Newborn; Urea | 1987 |
A new treatment of ichthyosis and other hyperkeratotic conditions.
Topics: Adolescent; Adult; Aged; Eczema; Female; Humans; Humidity; Ichthyosis; Male; Ointments; Psoriasis; S | 1968 |
Recent therapeutic advances for common cutaneous problems.
Topics: Acne Vulgaris; Administration, Topical; Coloring Agents; Cytarabine; Dermatologic Agents; Ethyl Ethe | 1974 |
Urea for treatment of dry skin.
Topics: Administration, Topical; Costs and Cost Analysis; Drug Evaluation; Humans; Ichthyosis; Pruritus; Ski | 1973 |
Urea in the topical treatment of atopic eczema.
Topics: Adult; Betamethasone; Child; Child, Preschool; Chronic Disease; Dermatologic Agents; Eczema; Foot De | 1971 |
Urea cream for dry skin.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Ichthyosis; Male; Middle Aged; Ointments; Skin; Urea | 1971 |
[An unknowed keratolytic agent: urea].
Topics: Aspirin; Dermatologic Agents; Drug Combinations; Humans; Ichthyosis; Lanolin; Psoriasis; Urea | 1971 |
Therapeutics 13. Urea as a topical agent.
Topics: Animals; Humans; Ichthyosis; Protein Denaturation; Pruritus; Skin; Solvents; Urea; Wound Infection | 1971 |
Calmurid: a urea cream for the skin.
Topics: Humans; Ichthyosis; Keratosis; Ointments; Urea | 1971 |
[Carbamide cream for dry and hyperkeratotic skin].
Topics: Dermatologic Agents; Humans; Ichthyosis; Ointments; Prurigo; Urea | 1968 |