urea has been researched along with Tuberculosis in 29 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Tuberculosis: Any of the infectious diseases of man and other animals caused by species of MYCOBACTERIUM TUBERCULOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Urea breath testing may provide a useful diagnostic and biomarker assay for tuberculosis and for treatment response." | 7.76 | 13[C]-urea breath test as a novel point-of-care biomarker for tuberculosis treatment and diagnosis. ( Atudorei, V; Bishai, WR; Choi, SW; Deretic, V; Jassal, MS; Lee, JH; Nedeltchev, GG; Sharp, ZD; Timmins, GS, 2010) |
| "tuberculosis is reported." | 5.42 | 3D-QSAR Selectivity Analysis of 1-Adamantyl-3-Heteroaryl Urea Analogs as Potent Inhibitors of Mycobacterium tuberculosis. ( Bagchi, S; Sharma, A; Wadhwa, P, 2015) |
| " However, these compounds suffered from poor in vitro pharmacokinetic (PK) profiles and they have a similar structure/SAR to inhibitors of human soluble epoxide hydrolase (sEH) enzymes." | 5.39 | Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties. ( Bruhn, DF; Grzegorzewicz, A; Hess, T; Jackson, M; Jones, V; Lee, RE; Maddox, MM; McNeil, MR; Morisseau, C; North, EJ; Scarborough, JS; Scherman, MS; Yang, L, 2013) |
| "Urea breath testing may provide a useful diagnostic and biomarker assay for tuberculosis and for treatment response." | 3.76 | 13[C]-urea breath test as a novel point-of-care biomarker for tuberculosis treatment and diagnosis. ( Atudorei, V; Bishai, WR; Choi, SW; Deretic, V; Jassal, MS; Lee, JH; Nedeltchev, GG; Sharp, ZD; Timmins, GS, 2010) |
| "tuberculosis is reported." | 1.42 | 3D-QSAR Selectivity Analysis of 1-Adamantyl-3-Heteroaryl Urea Analogs as Potent Inhibitors of Mycobacterium tuberculosis. ( Bagchi, S; Sharma, A; Wadhwa, P, 2015) |
| " However, these compounds suffered from poor in vitro pharmacokinetic (PK) profiles and they have a similar structure/SAR to inhibitors of human soluble epoxide hydrolase (sEH) enzymes." | 1.39 | Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties. ( Bruhn, DF; Grzegorzewicz, A; Hess, T; Jackson, M; Jones, V; Lee, RE; Maddox, MM; McNeil, MR; Morisseau, C; North, EJ; Scarborough, JS; Scherman, MS; Yang, L, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (68.97) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 6 (20.69) | 24.3611 |
| 2020's | 2 (6.90) | 2.80 |
| Authors | Studies |
|---|---|
| Sivangala Thandi, R | 1 |
| Radhakrishnan, RK | 1 |
| Tripathi, D | 1 |
| Paidipally, P | 1 |
| Azad, AK | 1 |
| Schlesinger, LS | 1 |
| Samten, B | 1 |
| Mulik, S | 1 |
| Vankayalapati, R | 1 |
| Madacki, J | 1 |
| Kopál, M | 1 |
| Jackson, M | 2 |
| Korduláková, J | 1 |
| North, EJ | 1 |
| Scherman, MS | 1 |
| Bruhn, DF | 1 |
| Scarborough, JS | 1 |
| Maddox, MM | 1 |
| Jones, V | 1 |
| Grzegorzewicz, A | 1 |
| Yang, L | 1 |
| Hess, T | 1 |
| Morisseau, C | 1 |
| McNeil, MR | 1 |
| Lee, RE | 1 |
| Kale, MG | 1 |
| Raichurkar, A | 1 |
| P, SH | 1 |
| Waterson, D | 1 |
| McKinney, D | 1 |
| Manjunatha, MR | 1 |
| Kranthi, U | 1 |
| Koushik, K | 1 |
| Jena, Lk | 1 |
| Shinde, V | 1 |
| Rudrapatna, S | 1 |
| Barde, S | 1 |
| Humnabadkar, V | 1 |
| Madhavapeddi, P | 1 |
| Basavarajappa, H | 1 |
| Ghosh, A | 1 |
| Ramya, VK | 1 |
| Guptha, S | 1 |
| Sharma, S | 1 |
| Vachaspati, P | 1 |
| Kumar, KN | 1 |
| Giridhar, J | 1 |
| Reddy, J | 1 |
| Panduga, V | 1 |
| Ganguly, S | 1 |
| Ahuja, V | 1 |
| Gaonkar, S | 1 |
| Kumar, CN | 1 |
| Ogg, D | 1 |
| Tucker, JA | 1 |
| Boriack-Sjodin, PA | 1 |
| de Sousa, SM | 1 |
| Sambandamurthy, VK | 1 |
| Ghorpade, SR | 1 |
| Wadhwa, P | 1 |
| Bagchi, S | 1 |
| Sharma, A | 1 |
| Maiga, M | 1 |
| Cohen, K | 1 |
| Baya, B | 1 |
| Srikrishna, G | 1 |
| Siddiqui, S | 1 |
| Sanogo, M | 1 |
| Somboro, AM | 1 |
| Diarra, B | 1 |
| Diallo, MH | 1 |
| Mazumdar, V | 1 |
| Yoder, C | 1 |
| Orsega, S | 1 |
| Belson, M | 1 |
| Kassambara, H | 1 |
| Goita, D | 1 |
| Murphy, RL | 1 |
| Dao, S | 1 |
| Polis, M | 1 |
| Diallo, S | 1 |
| Timmins, GS | 2 |
| Dodd, L | 1 |
| Earl, AM | 1 |
| Bishai, WR | 2 |
| Upadhayaya, RS | 1 |
| Kulkarni, GM | 1 |
| Vasireddy, NR | 1 |
| Vandavasi, JK | 1 |
| Dixit, SS | 1 |
| Sharma, V | 1 |
| Chattopadhyaya, J | 1 |
| Jassal, MS | 1 |
| Nedeltchev, GG | 1 |
| Lee, JH | 1 |
| Choi, SW | 1 |
| Atudorei, V | 1 |
| Sharp, ZD | 1 |
| Deretic, V | 1 |
| Stuart-Clark, H | 1 |
| Vorajee, N | 1 |
| Zuma, S | 1 |
| Van Niekerk, L | 1 |
| Burch, V | 1 |
| Raubenheimer, P | 1 |
| Peter, JG | 1 |
| ILAND, CN | 2 |
| AUFDERMAUR, M | 1 |
| BRODHAGE, H | 1 |
| LUISETTI, GL | 1 |
| ABBATE, G | 1 |
| CORSITTO, A | 1 |
| JOHANNES, T | 1 |
| HEINZ, K | 1 |
| LITYNSKI, M | 1 |
| LENCI, E | 1 |
| PALLONE, E | 1 |
| AMATO, A | 1 |
| GRASSI-GIALDRONI, G | 1 |
| VERGANI, F | 1 |
| CAMURATI, E | 1 |
| CAZZANI, E | 1 |
| GRASSI, C | 1 |
| BROBERGER, O | 1 |
| WINBERG, J | 1 |
| ZETTERSTROM, R | 1 |
| BRADBURY, MW | 1 |
| STUBBS, J | 1 |
| HUGHES, IE | 1 |
| PARKER, P | 1 |
| WOLFROMM, G | 1 |
| BROCARD, H | 1 |
| GALLOUEDEC, C | 1 |
| GRAND, A | 1 |
| BENDITT, EP | 1 |
| ERIKSEN, N | 1 |
| SEMB, C | 1 |
| MARTENYI, G | 1 |
| JESPERSEN, A | 1 |
| LUCIEN, P | 1 |
| MOREL, R | 1 |
| OUVRY, JE | 1 |
| Kennedy, AC | 1 |
| Burton, JA | 1 |
| Allison, ME | 1 |
| Pershin, GN | 1 |
| Zykova, TN | 1 |
| Wagner, WH | 1 |
| Winkelmann, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Sensitivity and Specificity of Oral Urea Breath Testing for Presumptive Diagnosis and Treatment Response in Pulmonary Tuberculosis in Bamako, Mali[NCT01301144] | 113 participants (Actual) | Observational | 2011-02-13 | Completed | |||
| A Randomised Controlled Trial of an Integrated Post-discharge Transitional Care Package for General Medical In-patients in Cape Town, South Africa[NCT01916876] | 0 participants (Actual) | Interventional | 2015-03-31 | Withdrawn (stopped due to Funding shortage) | |||
| "Validation Study of the 4-question RACYDelirium Screening Tool in General Medical In-patients From a Developing Country Setting"[NCT01916889] | 1,093 participants (Actual) | Interventional | 2013-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
29 other studies available for urea and Tuberculosis
| Article | Year |
|---|---|
Ornithine-A urea cycle metabolite enhances autophagy and controls Mycobacterium tuberculosis infection.
Topics: Ammonia; Animals; Apoptosis; Arginase; Atropine; Autophagy; Cell Proliferation; Disease Progression; | 2020 |
Mycobacterial Epoxide Hydrolase EphD Is Inhibited by Urea and Thiourea Derivatives.
Topics: Adamantane; Epoxide Hydrolases; Gene Expression Regulation, Bacterial; Humans; Mycobacterium tubercu | 2021 |
Design, synthesis and anti-tuberculosis activity of 1-adamantyl-3-heteroaryl ureas with improved in vitro pharmacokinetic properties.
Topics: Animals; Antitubercular Agents; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Dru | 2013 |
Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA Gyrase B.
Topics: Animals; Antitubercular Agents; Disease Models, Animal; DNA Gyrase; Dose-Response Relationship, Drug | 2013 |
3D-QSAR Selectivity Analysis of 1-Adamantyl-3-Heteroaryl Urea Analogs as Potent Inhibitors of Mycobacterium tuberculosis.
Topics: Adamantane; Antitubercular Agents; Bacterial Proteins; Computer-Aided Design; Drug Discovery; Epoxid | 2015 |
Stool microbiome reveals diverse bacterial ureases as confounders of oral urea breath testing for Helicobacter pylori and Mycobacterium tuberculosis in Bamako, Mali.
Topics: Adult; Breath Tests; Demography; Feces; Female; Helicobacter Infections; Helicobacter pylori; Humans | 2016 |
Design, synthesis and biological evaluation of novel triazole, urea and thiourea derivatives of quinoline against Mycobacterium tuberculosis.
Topics: Animals; Antitubercular Agents; ATP Synthetase Complexes; Bacterial Proteins; Cell Survival; Macroph | 2009 |
13[C]-urea breath test as a novel point-of-care biomarker for tuberculosis treatment and diagnosis.
Topics: Animals; Biomarkers; Breath Tests; Bronchoscopy; Carbon Isotopes; Immunization; Lung; Mycobacterium | 2010 |
Twelve-month outcomes of patients admitted to the acute general medical service at Groote Schuur Hospital.
Topics: Activities of Daily Living; Adult; Age Factors; Aged; Confidence Intervals; Employment; Female; Foll | 2012 |
Twelve-month outcomes of patients admitted to the acute general medical service at Groote Schuur Hospital.
Topics: Activities of Daily Living; Adult; Age Factors; Aged; Confidence Intervals; Employment; Female; Foll | 2012 |
Twelve-month outcomes of patients admitted to the acute general medical service at Groote Schuur Hospital.
Topics: Activities of Daily Living; Adult; Age Factors; Aged; Confidence Intervals; Employment; Female; Foll | 2012 |
Twelve-month outcomes of patients admitted to the acute general medical service at Groote Schuur Hospital.
Topics: Activities of Daily Living; Adult; Age Factors; Aged; Confidence Intervals; Employment; Female; Foll | 2012 |
Immunising properties of a urea-killed tubercle vaccine.
Topics: BCG Vaccine; Humans; Mycobacterium bovis; Tuberculin; Tuberculin Test; Tuberculosis; Urea; Vaccinati | 1953 |
[Experimental study of BCG and urea-treated tubercle bacilli].
Topics: Bacillus; Mycobacterium bovis; Mycobacterium tuberculosis; Tuberculosis; Urea; Vaccination; Vaccines | 1955 |
[Liver function tests in diabetics with tuberculosis treated with N-sulfanilyl-N'-butyl urea].
Topics: Diabetes Complications; Diabetes Mellitus; Humans; Liver; Liver Function Tests; Sulfanilamide; Sulfa | 1957 |
[Diabetes mellitus and pulmonary tuberculosis in oral treatment of diabetes].
Topics: Diabetes Complications; Diabetes Mellitus; Humans; Sulfanilamide; Sulfanilamides; Tuberculosis; Tube | 1956 |
[Effect of N1-sulfanilylo-N2-n-butyl-carbamide in diabetes complicated by tuberculosis].
Topics: Diabetes Mellitus; Hypoglycemic Agents; Tuberculosis; Tuberculosis, Pulmonary; Urea | 1957 |
[N-sulfanilyl-N'-butyl urea (BZ55) therapy of diabetes in patients of pulmonary tuberculosis].
Topics: Diabetes Mellitus; Humans; Hypoglycemic Agents; Tuberculosis; Tuberculosis, Pulmonary; Urea | 1958 |
[Early results of sulfanilyl urea therapy of diabetic patients of pulmonary tuberculosis].
Topics: Diabetes Mellitus; Humans; Tuberculosis; Tuberculosis, Pulmonary; Urea | 1958 |
[Experimental and clinical studies on the use of sulfonyl ureas in tuberculous diabetics].
Topics: Diabetes Mellitus; Humans; Hypoglycemic Agents; Tuberculosis; Tuberculosis, Pulmonary; Urea | 1958 |
Juvenile nephronophthisis. Part 1. A genetically determined nephropathy with hypotonic polyuria and azotaemia.
Topics: Blood Urea Nitrogen; Child; Humans; Infant; Kidney; Kidney Diseases; Kidney Diseases, Cystic; Polyur | 1960 |
THE DISTRIBUTION OF POTASSIUM, SODIUM, CHLORIDE AND UREA BETWEEN LUMBAR CEREBROSPINAL FLUID AND BLOOD SERUM IN HUMAN SUBJECTS.
Topics: Anions; Blood; Cerebrospinal Fluid; Chlorides; Humans; Ions; Neurology; Potassium; Serum; Sodium; So | 1963 |
[RENAL INSUFFICIENCY AND RENAL TUBERCULOSIS. SUMMARY VIEWS OF A SURGEON].
Topics: Albuminuria; Diagnosis; Female; Humans; Kidney; Kidney Function Tests; Nephrectomy; Pregnancy; Renal | 1964 |
[GOODPASTURE'S PNEUMO-RENAL SYNDROME].
Topics: Acute Kidney Injury; Anti-Glomerular Basement Membrane Disease; Diagnosis, Differential; Glomerulone | 1964 |
AMYLOID. II. STARCH GEL ELECTROPHORETIC ANALYSIS OF SOME PROTEINS EXTRACTED FROM AMYLOID.
Topics: Adolescent; Amyloid; Amyloidosis; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Bronchiecta | 1964 |
CONSERVATIVE KIDNEY SURGERY; PARTIAL KIDNEY RESECTION.
Topics: Edema; Geriatrics; Humans; Hydronephrosis; Hypothermia; Hypothermia, Induced; Kidney; Kidney Calculi | 1965 |
[Sedatives in the treatment of pulmonary tuberculosis].
Topics: Hypnotics and Sedatives; Tuberculosis; Tuberculosis, Pulmonary; Urea | 1955 |
The effect of various factors on the immunising power of a urea-killed tubercle vaccine.
Topics: Immunization; Tuberculosis; Urea; Vaccination; Vaccines | 1955 |
[Treatment of residual cavities in thoracoplasty by directed endocavitary injections of quinine urea salts].
Topics: Humans; Quinine; Salts; Thoracoplasty; Thorax; Torso; Tuberculosis; Tuberculosis, Pulmonary; Urea | 1950 |
Tuberculosis as a continuing cause of renal amyloidosis.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Autopsy; Biopsy; C | 1974 |
[Experimental study on the antitubercular activity of butomelide].
Topics: Animals; Antitubercular Agents; Chemical Phenomena; Chemistry; Guinea Pigs; Mice; Mycobacterium tube | 1972 |
[Tuberculostatic active N,N'-diarylthioureas. 2].
Topics: Animals; Antitubercular Agents; Chemistry, Pharmaceutical; Guinea Pigs; Kidney; Liver; Mice; Mycobac | 1969 |