urea has been researched along with Tremor in 16 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Tremor: Cyclical movement of a body part that can represent either a physiologic process or a manifestation of disease. Intention or action tremor, a common manifestation of CEREBELLAR DISEASES, is aggravated by movement. In contrast, resting tremor is maximal when there is no attempt at voluntary movement, and occurs as a relatively frequent manifestation of PARKINSON DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A potent 5-hydroxytryptamine (5-HT)2A receptor inverse agonist and antagonist, ACP-103 [N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1, active:salt)], was evaluated for its ability to reduce the primary motor symptom of tremor using tacrine-induced tremulous jaw movements in rats, which is an animal model of parkinsonian tremor." | 7.74 | A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model. ( Betz, AJ; Bibbiani, F; Chase, TN; Davis, RE; Kielaite, A; Salamone, JD; Vanover, KE; Weber, SM; Weiner, DM, 2008) |
| "N-Carbamoyl-2-(2,6-dichlorophenyl)acetamidine HCl (LON 954), a tremorogenic drug, inhibited MAO activity in various tissue preparations in a reversible, competitive manner showing some degree of selectivity towards type-B MAO." | 7.67 | Monoamine oxidase inhibition by the tremorogenic drug--LON 954. ( Ganguly, DK; Guha, SR; Mitra, C, 1984) |
| "The tremors induced by harmine, LON-954 (N-carbamoyl-2-(2,6-dichlorophenyl)acetamidine hydrochloride) and 5-hydroxytryptophan (5-HTP) were studied in control rats and in rats withdrawn for 16-48 hrs from 6 to 9 days' ethanol administration." | 7.67 | Harmine-, LON-954- and 5-hydroxytryptophan-induced tremors in rats withdrawn from ethanol. ( Gothóni, P, 1985) |
| "Tremor produced in laboratory mice by the benzylimidoylurea derivative LON 954 was potentiated in a dose-dependent manner by a variety of typical and atypical neuroleptics." | 7.66 | Potentiation of LON 954 tremor by typical and atypical neuroleptics--an indication of striatal dopamine antagonism. ( Coward, DM; Doggett, NS, 1980) |
| "A potent 5-hydroxytryptamine (5-HT)2A receptor inverse agonist and antagonist, ACP-103 [N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1, active:salt)], was evaluated for its ability to reduce the primary motor symptom of tremor using tacrine-induced tremulous jaw movements in rats, which is an animal model of parkinsonian tremor." | 3.74 | A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model. ( Betz, AJ; Bibbiani, F; Chase, TN; Davis, RE; Kielaite, A; Salamone, JD; Vanover, KE; Weber, SM; Weiner, DM, 2008) |
| "N-Carbamoyl-2-(2,6-dichlorophenyl)acetamidine HCl (LON 954), a tremorogenic drug, inhibited MAO activity in various tissue preparations in a reversible, competitive manner showing some degree of selectivity towards type-B MAO." | 3.67 | Monoamine oxidase inhibition by the tremorogenic drug--LON 954. ( Ganguly, DK; Guha, SR; Mitra, C, 1984) |
| "The tremors induced by harmine, LON-954 (N-carbamoyl-2-(2,6-dichlorophenyl)acetamidine hydrochloride) and 5-hydroxytryptophan (5-HTP) were studied in control rats and in rats withdrawn for 16-48 hrs from 6 to 9 days' ethanol administration." | 3.67 | Harmine-, LON-954- and 5-hydroxytryptophan-induced tremors in rats withdrawn from ethanol. ( Gothóni, P, 1985) |
| "Tremor produced in laboratory mice by the benzylimidoylurea derivative LON 954 was potentiated in a dose-dependent manner by a variety of typical and atypical neuroleptics." | 3.66 | Potentiation of LON 954 tremor by typical and atypical neuroleptics--an indication of striatal dopamine antagonism. ( Coward, DM; Doggett, NS, 1980) |
| "N-carbamoyl-2-(2,6-dichlorophenyl) acetamidine hydrochloride (LON 954) causes a reproducible rest tremor in mice, of rapid onset and short duration with no associated rigidity or akinesia and in the absence of any marked changes in body temperature or accompanying peripheral parasympathomimetic effects." | 3.65 | The production of an alternative laboratory model of the Parkinson syndrome using a new benzylimidoylurea derivative LON 954. ( Coward, DM; Doggett, NS, 1977) |
| "The tremorogenic properties of a series of benzylimidoylurea derivatives are described." | 3.65 | The pharmacology of N-carbamoyl-2-(2,6-dichlorophenyl)acetamidine hydrochloride (LON-954) a new tremorogenic agent. ( Coward, DM; Doggett, NS; Sayers, AC, 1977) |
| " The alterations in the levels of the indoleamine in tuberculum olfactorium and its relationship with dosage as well as duration and intensity of LON-954 tremor indicate the involvement of the mesolimbic system in its action." | 1.28 | Tremorogenesis by LON-954 [N-carbamoyl-2-(2,6-dichlorophenyl) acetamidine hydrochloride]: evidence for the involvement of 5-hydroxytryptamine. ( Ganguly, DK; Mohanakumar, KP, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (93.75) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vanover, KE | 1 |
| Betz, AJ | 1 |
| Weber, SM | 1 |
| Bibbiani, F | 1 |
| Kielaite, A | 1 |
| Weiner, DM | 1 |
| Davis, RE | 1 |
| Chase, TN | 1 |
| Salamone, JD | 1 |
| Coward, DM | 3 |
| Doggett, NS | 3 |
| Mitra, C | 1 |
| Ganguly, DK | 4 |
| Guha, SR | 1 |
| Ross, HG | 1 |
| Cleveland, S | 1 |
| Vedasiromoni, JR | 1 |
| Kunze, U | 1 |
| Sayers, AC | 1 |
| Ha, YH | 1 |
| Milner, JA | 1 |
| Corbin, JE | 1 |
| Mohanakumar, KP | 1 |
| Gothóni, P | 1 |
| Mitema, ES | 1 |
| Weinstein, S | 1 |
| Gertner, SB | 1 |
| Tyler, HR | 1 |
| Johnson, WJ | 1 |
| Hagge, WW | 1 |
| Wagoner, RD | 1 |
| Dinapoli, RP | 1 |
| Rosevear, JW | 1 |
| Koyama, T | 1 |
| Handa, J | 1 |
| Handa, H | 1 |
| Matsumoto, S | 1 |
16 other studies available for urea and Tremor
| Article | Year |
|---|---|
A 5-HT2A receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model.
Topics: Animals; Data Interpretation, Statistical; Dopamine Agents; Dyskinesia, Drug-Induced; Jaw; Levodopa; | 2008 |
Potentiation of LON 954 tremor by typical and atypical neuroleptics--an indication of striatal dopamine antagonism.
Topics: Animals; Antipsychotic Agents; Corpus Striatum; Dopamine Antagonists; Dose-Response Relationship, Dr | 1980 |
Monoamine oxidase inhibition by the tremorogenic drug--LON 954.
Topics: Animals; Brain; Dopamine; Guinea Pigs; In Vitro Techniques; Kinetics; Mitochondria, Liver; Monoamine | 1984 |
Electrophysiological studies with LON-954, a tremorogen, in the cat spinal cord.
Topics: Animals; Cats; Decerebrate State; Electrophysiology; Evoked Potentials; Female; Levodopa; Male; Refl | 1984 |
N-carbamoyl-2-(2,6-dichlorophenyl) acetamidine hydrochloride (LON-954), a tremorogen, on rat diaphragm.
Topics: Animals; Diaphragm; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle Denervation; Muscl | 1984 |
Chronic bromide intoxication with a severe neurological deficit.
Topics: Adult; Bromides; Cerebellar Ataxia; Delirium; Eye Manifestations; Female; Humans; Neurologic Manifes | 1976 |
The production of an alternative laboratory model of the Parkinson syndrome using a new benzylimidoylurea derivative LON 954.
Topics: Animals; Antiparkinson Agents; Benzimidazoles; Disease Models, Animal; Drug Evaluation, Preclinical; | 1977 |
The pharmacology of N-carbamoyl-2-(2,6-dichlorophenyl)acetamidine hydrochloride (LON-954) a new tremorogenic agent.
Topics: Analgesics; Animals; Cats; Decerebrate State; Dogs; Drug Interactions; Drug Tolerance; Female; Levod | 1977 |
Arginine requirements in immature dogs.
Topics: Amino Acids; Ammonia; Animals; Arginine; Citrates; Dogs; Hyperglycemia; Nutritional Requirements; Or | 1978 |
Tremorogenesis by LON-954 [N-carbamoyl-2-(2,6-dichlorophenyl) acetamidine hydrochloride]: evidence for the involvement of 5-hydroxytryptamine.
Topics: Animals; Basal Ganglia; Dose-Response Relationship, Drug; Female; Male; Medulla Oblongata; Olfactory | 1989 |
Harmine-, LON-954- and 5-hydroxytryptophan-induced tremors in rats withdrawn from ethanol.
Topics: 5-Hydroxytryptophan; Alkaloids; Animals; Ethanol; Harmine; Male; Physostigmine; Rats; Rats, Inbred S | 1985 |
Comparative studies of the effects of quinuronium sulfate and diminazene diaceturate in sheep.
Topics: Amidines; Animals; Antiprotozoal Agents; Ataxia; Behavior, Animal; Bilirubin; Blood Urea Nitrogen; C | 1985 |
The neurological and metabolic effects of streptozotocin in the cat.
Topics: Animals; Anorexia Nervosa; Anti-Bacterial Agents; Cats; Diabetes Mellitus; Fecal Incontinence; Gluco | 1971 |
Neurologic disorders seen in the uremic patient.
Topics: Blindness; Blood Urea Nitrogen; Blood-Brain Barrier; Brain; Cell Membrane Permeability; Electroencep | 1970 |
Effects of urea loading in patients with far-advanced renal failure.
Topics: Acute Kidney Injury; Creatine; Headache; Humans; Osmolar Concentration; Renal Dialysis; Time Factors | 1972 |
Methylnitrosourea-induced malformations of brain in SD-JCL rat.
Topics: Abnormalities, Drug-Induced; Animals; Ataxia; Brain; Embryo, Mammalian; Encephalocele; Female; Gesta | 1970 |