urea has been researched along with Protein Aggregation, Pathological in 8 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Protein Aggregation, Pathological: A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Alzheimer's disease is a severe brain illness that causes vast numbers of nerve cells in the brain to die, driven by the production and deposition of amyloid beta (Aβ) peptides." | 1.48 | Synergistic approaches unraveling regulation and aggregation of intrinsically disordered β-amyloids implicated in Alzheimer's disease. ( Grover, A; Kumari, A; Rajput, R; Shrivastava, N; Somvanshi, P, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamza, A | 1 |
| Samad, A | 1 |
| Imam, MA | 1 |
| Faizan, MI | 1 |
| Ahmed, A | 1 |
| Almajhdi, FN | 1 |
| Hussain, T | 1 |
| Islam, A | 1 |
| Parveen, S | 1 |
| Xia, K | 1 |
| Anand, DV | 1 |
| Shikhar, S | 1 |
| Mu, Y | 1 |
| Kushwah, N | 1 |
| Jain, V | 1 |
| Yadav, D | 1 |
| Khan, MAI | 1 |
| Respondek, M | 1 |
| Kjellström, S | 1 |
| Deep, S | 1 |
| Linse, S | 1 |
| Akke, M | 1 |
| Sun, X | 1 |
| Dyson, HJ | 1 |
| Wright, PE | 1 |
| Kumari, A | 1 |
| Rajput, R | 1 |
| Shrivastava, N | 1 |
| Somvanshi, P | 1 |
| Grover, A | 1 |
| Hsu, PH | 1 |
| Lin, YT | 1 |
| Chung, YH | 1 |
| Lin, KJ | 1 |
| Yang, LY | 1 |
| Yen, TC | 1 |
| Liu, HL | 1 |
| Levine, ZA | 1 |
| Larini, L | 1 |
| LaPointe, NE | 1 |
| Feinstein, SC | 1 |
| Shea, JE | 1 |
1 review available for urea and Protein Aggregation, Pathological
| Article | Year |
|---|---|
Osmolytes: A Possible Therapeutic Molecule for Ameliorating the Neurodegeneration Caused by Protein Misfolding and Aggregation.
Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Animals; Brain; Carbohydrate Metabolism; Drug | 2020 |
7 other studies available for urea and Protein Aggregation, Pathological
| Article | Year |
|---|---|
Structural Characterization of Ectodomain G Protein of Respiratory Syncytial Virus and Its Interaction with Heparan Sulfate: Multi-Spectroscopic and In Silico Studies Elucidating Host-Pathogen Interactions.
Topics: Catalytic Domain; Cell Membrane; Heparitin Sulfate; Host-Pathogen Interactions; Humans; Hydrogen Bon | 2021 |
Persistent homology analysis of osmolyte molecular aggregation and their hydrogen-bonding networks.
Topics: Entropy; Hydrogen; Hydrogen Bonding; Methylamines; Molecular Dynamics Simulation; Protein Aggregatio | 2019 |
Cu/Zn Superoxide Dismutase Forms Amyloid Fibrils under Near-Physiological Quiescent Conditions: The Roles of Disulfide Bonds and Effects of Denaturant.
Topics: Amyloid; Escherichia coli; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectros | 2017 |
Fluorotryptophan Incorporation Modulates the Structure and Stability of Transthyretin in a Site-Specific Manner.
Topics: Amino Acid Substitution; Dimerization; Fluorescent Dyes; Kinetics; Models, Molecular; Mutation; Nucl | 2017 |
Synergistic approaches unraveling regulation and aggregation of intrinsically disordered β-amyloids implicated in Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Humans; Intrinsically Disordered Proteins; Methylamines; P | 2018 |
Focused Ultrasound-Induced Blood-Brain Barrier Opening Enhances GSK-3 Inhibitor Delivery for Amyloid-Beta Plaque Reduction.
Topics: Amyloid beta-Peptides; Animals; Biomarkers; Blood-Brain Barrier; Brain; Enzyme Inhibitors; Glycogen | 2018 |
Regulation and aggregation of intrinsically disordered peptides.
Topics: Humans; Methylamines; Molecular Dynamics Simulation; Peptides; Protein Aggregation, Pathological; Pr | 2015 |