urea has been researched along with Polycystic Kidney, Autosomal Dominant in 11 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Polycystic Kidney, Autosomal Dominant: Kidney disorders with autosomal dominant inheritance and characterized by multiple CYSTS in both KIDNEYS with progressive deterioration of renal function.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The urine-to-plasma urea ratio, which is calculated from routine laboratory measurements, predicts disease progression in ADPKD in addition to other risk markers." | 8.02 | Use of the Urine-to-Plasma Urea Ratio to Predict ADPKD Progression. ( Boertien, WE; Casteleijn, NF; Gansevoort, RT; Heida, JE; Meijer, E; Messchendorp, AL; Zittema, D, 2021) |
| " The aim of this study was to determine if a diet, appropriate for persons of most ages, reduces the excretion of sodium, urea, acid, and decreases mean urine osmolality while gaining acceptance by patients with autosomal dominant polycystic kidney disease (ADPKD)." | 5.24 | Diet and polycystic kidney disease: A pilot intervention study. ( Carlson, SE; Creed, C; Gibson, CA; Grantham, JJ; Hamilton-Reeves, JM; Sullivan, DK; Taylor, JM; Wesson, DE, 2017) |
| "The urine-to-plasma urea ratio, which is calculated from routine laboratory measurements, predicts disease progression in ADPKD in addition to other risk markers." | 4.02 | Use of the Urine-to-Plasma Urea Ratio to Predict ADPKD Progression. ( Boertien, WE; Casteleijn, NF; Gansevoort, RT; Heida, JE; Meijer, E; Messchendorp, AL; Zittema, D, 2021) |
| "Tolvaptan, a vasopressin V2 receptor antagonist, slows the decline in renal function in autosomal dominant polycystic kidney disease (ADPKD)." | 3.96 | Sodium and urea excretion as determinants of urine output in autosomal dominant polycystic kidney disease patients on V2 receptor antagonists: impact of dietary intervention. ( Agharazii, M; Asselin-Thompstone, L; Côté, G; Desmeules, S; Lacroix, C; Mac-Way, F; René de Cotret, P, 2020) |
| "Also, in kidneys of ADPKD patients collapsed cysts were observed, in addition to massive fibrosis and immune infiltrates." | 1.39 | Cyst expansion and regression in a mouse model of polycystic kidney disease. ( Breuning, MH; de Heer, E; Happé, H; Leonhard, WN; Peters, DJ; Salvatori, DC; van der Wal, AM, 2013) |
| "A total of 92 adult ADPKD patients of both genders were studied, none of which presented end-stage renal disease (ESRD), and classified according to an ultrasound score based on kidney size and number of cysts." | 1.33 | A comparative study of three kidney biomarker tests in autosomal-dominant polycystic kidney disease. ( Casal, JA; Hermida, J; Lens, XM; Tutor, JC, 2005) |
| "Effective treatment of ADPKD in this rat model requires early administration of a readily absorbed alkalinizing citrate salt." | 1.32 | Dietary citrate treatment of polycystic kidney disease in rats. ( Tanner, GA; Tanner, JA, 2003) |
| "An exact description of the course of chronic renal failure in this strain, however, is still missing." | 1.29 | Progression of chronic renal failure in a rat strain with autosomal dominant polycystic kidney disease. ( Gretz, N, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 2 (18.18) | 2.80 |
| Authors | Studies |
|---|---|
| Côté, G | 1 |
| Asselin-Thompstone, L | 1 |
| Mac-Way, F | 1 |
| René de Cotret, P | 1 |
| Lacroix, C | 1 |
| Desmeules, S | 1 |
| Agharazii, M | 1 |
| Heida, JE | 1 |
| Gansevoort, RT | 1 |
| Messchendorp, AL | 1 |
| Meijer, E | 1 |
| Casteleijn, NF | 1 |
| Boertien, WE | 1 |
| Zittema, D | 1 |
| Happé, H | 1 |
| van der Wal, AM | 1 |
| Salvatori, DC | 1 |
| Leonhard, WN | 1 |
| Breuning, MH | 1 |
| de Heer, E | 1 |
| Peters, DJ | 1 |
| Taylor, JM | 1 |
| Hamilton-Reeves, JM | 1 |
| Sullivan, DK | 1 |
| Gibson, CA | 1 |
| Creed, C | 1 |
| Carlson, SE | 1 |
| Wesson, DE | 1 |
| Grantham, JJ | 1 |
| Bankir, L | 1 |
| Bichet, DG | 1 |
| Tanner, GA | 1 |
| Tanner, JA | 1 |
| Wang, D | 1 |
| Braendstrup, O | 1 |
| Larsen, S | 1 |
| Horn, T | 1 |
| Strandgaard, S | 1 |
| Casal, JA | 1 |
| Hermida, J | 1 |
| Lens, XM | 1 |
| Tutor, JC | 1 |
| Gretz, N | 3 |
| Ceccherini, I | 2 |
| Kränzlin, B | 2 |
| Klöting, I | 1 |
| Devoto, M | 1 |
| Rohmeiss, P | 1 |
| Hocher, B | 1 |
| Waldherr, R | 1 |
| Romeo, G | 2 |
| Bihoreau, MT | 1 |
| Browne, J | 1 |
| Lathrop, GM | 1 |
| James, MR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A New Diet for Patients With Autosomal Dominant Polycystic Disease (ADPKD)[NCT01810614] | 12 participants (Actual) | Interventional | 2013-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for urea and Polycystic Kidney, Autosomal Dominant
| Article | Year |
|---|---|
Diet and polycystic kidney disease: A pilot intervention study.
Topics: Adult; Cohort Studies; Cross-Sectional Studies; Diet; Diet Records; Dietary Proteins; Feasibility St | 2017 |
10 other studies available for urea and Polycystic Kidney, Autosomal Dominant
| Article | Year |
|---|---|
Sodium and urea excretion as determinants of urine output in autosomal dominant polycystic kidney disease patients on V2 receptor antagonists: impact of dietary intervention.
Topics: Adult; Antidiuretic Hormone Receptor Antagonists; Dietary Proteins; Directive Counseling; Diuresis; | 2020 |
Use of the Urine-to-Plasma Urea Ratio to Predict ADPKD Progression.
Topics: Adult; Biomarkers; Disease Progression; Fasting; Female; Glomerular Filtration Rate; Humans; Kidney; | 2021 |
Cyst expansion and regression in a mouse model of polycystic kidney disease.
Topics: Age Factors; Animals; Biomarkers; Disease Models, Animal; Disease Progression; Extracellular Matrix; | 2013 |
Polycystic kidney disease: An early urea-selective urine-concentrating defect in ADPKD.
Topics: Biomarkers; Glycopeptides; Humans; Polycystic Kidney, Autosomal Dominant; Urea; Vasopressins | 2012 |
Dietary citrate treatment of polycystic kidney disease in rats.
Topics: Animals; Animals, Congenic; Calcium; Calcium Citrate; Citrates; Creatinine; Disease Models, Animal; | 2003 |
The expression and activity of renal nitric oxide synthase and circulating nitric oxide in polycystic kidney disease rats.
Topics: Animals; Female; Immunohistochemistry; Kidney; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxi | 2004 |
A comparative study of three kidney biomarker tests in autosomal-dominant polycystic kidney disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albuminuria; beta-N-Acetylhexosaminidases; Biomarkers; C | 2005 |
Gender-dependent disease severity in autosomal polycystic kidney disease of rats.
Topics: Animals; Female; Kidney; Male; Organ Size; Polycystic Kidney, Autosomal Dominant; Rats; Rats, Inbred | 1995 |
Progression of chronic renal failure in a rat strain with autosomal dominant polycystic kidney disease.
Topics: Animals; Blood Pressure; Creatinine; Disease Progression; Kidney; Kidney Failure, Chronic; Longitudi | 1994 |
Location of the first genetic locus, PKDr1, controlling autosomal dominant polycystic kidney disease in Han:SPRD cy/+ rat.
Topics: Animals; Body Weight; Chromosome Mapping; Chromosomes, Human, Pair 8; Crosses, Genetic; Disease Mode | 1997 |