Page last updated: 2024-10-20

urea and Ovarian Neoplasms

urea has been researched along with Ovarian Neoplasms in 22 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.

Research Excerpts

ExcerptRelevanceReference
"In 14 out of the 20 pts (70 %) the recurrence occurred during chemotherapy or within 6 months after the end of the chemotherapy."2.71Treatment of recurrent epithelial ovarian cancer with secondary cytoreduction and continuous intraoperative intraperitoneal hyperthermic chemoperfusion (CIIPHCP). ( Chatzigeorgiou, K; Chatzigeorgiou, N; Chrysafis, G; Dimasis, A; Economou, S; Lyratzopoulos, N; Manolas, K; Minopoulos, G; Setzis, K; Zafiriou, G, 2003)
"Adriamycin (doxorubicin, Adriblastin) and cis-diammine-dichloro-platinum (II) (DDP, NSC 119 875) were used in the treatment of 18 patients with ovarian carcinoma, usually after intensive pre-treatment, both in a dosage of 50 mg/m2 once every 4 weeks."2.64[Combination of adriamycin and cis-diammine-dichloro-platinum (II) in the treatment of advanced, therapy-resistant, ovarian carcinoma (author's transl)]. ( Brunner, KW; Cavalli, F; Sonntag, RW; Stoller, U; Tschopp, L, 1978)
" Selectivity of protection by WR2721 is probably due to the preferential formation and uptake of the thiol metabolite 2-(3-aminopropylamino)ethanethiol (WR1065), which can inactivate toxic platinum-species inside the cell."1.28Time dependence of the selective modulation of cisplatin-induced nephrotoxicity by WR2721 in the mouse. ( Boven, E; Holwerda, U; Pinedo, HM; Treskes, M; van der Vijgh, WJ, 1992)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199010 (45.45)18.7374
1990's4 (18.18)18.2507
2000's3 (13.64)29.6817
2010's4 (18.18)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Gnanasekaran, KK1
Pouland, T2
Bunce, RA2
Darrell Berlin, K1
Abuskhuna, S1
Bhandari, D2
Mashayekhi, M2
Zhou, DH1
Benbrook, DM3
Meng, Y1
Chen, CW1
Yung, MMH1
Sun, W1
Sun, J1
Li, Z2
Li, J1
Zhou, W1
Liu, SS1
Cheung, ANY1
Ngan, HYS1
Braisted, JC1
Kai, Y1
Peng, W1
Tzatsos, A1
Li, Y1
Dai, Z1
Zheng, W1
Chan, DW1
Zhu, W1
Watts, FM1
Berlin, KD2
Zhou, D1
Itamochi, H1
Nishimura, M1
Oumi, N1
Kato, M1
Oishi, T1
Shimada, M1
Sato, S2
Naniwa, J1
Kudoh, A1
Kigawa, J1
Harada, T1
Bryant, C1
Rawlinson, R1
Massey, AJ1
Chatzigeorgiou, K1
Economou, S1
Chrysafis, G1
Dimasis, A1
Zafiriou, G1
Setzis, K1
Lyratzopoulos, N1
Minopoulos, G1
Manolas, K1
Chatzigeorgiou, N1
Liu, S1
Brown, CW1
Dhar, A1
Guruswamy, S1
Brown, D1
Gardner, GJ1
Birrer, MJ1
Ferriss, JB1
Brown, JJ1
Fraser, R1
Lever, AF1
Robertson, JI1
Hightower, RD1
Sevin, BU1
Perras, J1
Nguyen, H1
Angioli, R1
Untch, M1
Averette, H1
Andersson, H1
Lindegren, S1
Bäck, T1
Jacobsson, L1
Leser, G1
Horvath, G1
Zalutsky, MR1
Xu, FJ1
Yu, Y1
Foulon, CF1
Zhao, XG1
Slade, SK1
Affleck, DJ1
Bast, RC1
Visser, GW1
Klok, RP1
Gebbinck, JW1
ter Linden, T1
van Dongen, GA1
Molthoff, CF1
Gerber, AC1
Kozdrowski, I1
Wyss, SR1
Berger, EG1
Cavalli, F1
Stoller, U1
Tschopp, L1
Sonntag, RW1
Brunner, KW1
Wiltshaw, E1
Kroner, T1
Treskes, M1
Boven, E1
Holwerda, U1
Pinedo, HM1
van der Vijgh, WJ1
Qian, HN1
Feng, J1
Fu, TY1
Marsh, JC1
DeConti, RC1
Hubbard, SP1
Rustia, M1
McGowan, L1
Davis, RH1
Bunnag, B1
Ivankovic, S1
Black, JA1
Chan, GF1
Hew, CL1
Dixon, GH1

Reviews

1 review available for urea and Ovarian Neoplasms

ArticleYear
Primary hyperaldosteronism.
    Clinics in endocrinology and metabolism, 1981, Volume: 10, Issue:3

    Topics: Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged;

1981

Trials

4 trials available for urea and Ovarian Neoplasms

ArticleYear
Treatment of recurrent epithelial ovarian cancer with secondary cytoreduction and continuous intraoperative intraperitoneal hyperthermic chemoperfusion (CIIPHCP).
    Zentralblatt fur Gynakologie, 2003, Volume: 125, Issue:10

    Topics: Disease-Free Survival; Female; Humans; Hyperthermia, Induced; Intraoperative Care; Intraoperative Pe

2003
[Combination of adriamycin and cis-diammine-dichloro-platinum (II) in the treatment of advanced, therapy-resistant, ovarian carcinoma (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1978, Jun-02, Volume: 103, Issue:22

    Topics: Adult; Cisplatin; Clinical Trials as Topic; Creatinine; Doxorubicin; Drug Evaluation; Drug Resistanc

1978
Phase II study of cis-dichlorodiammineplatinum(II) (NSC-119875) in advanced adenocarcinoma of the ovary.
    Cancer treatment reports, 1976, Volume: 60, Issue:1

    Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Blood Platelets; Cisplatin; Drug Administration

1976
Treatment of Hodgkin's disease and other cancers with 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU; NSC-409962).
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:5

    Topics: Adenocarcinoma; Adenoma, Islet Cell; Adolescent; Adrenal Gland Neoplasms; Adult; Alkylating Agents;

1971

Other Studies

17 other studies available for urea and Ovarian Neoplasms

ArticleYear
Tetrahydroquinoline units in flexible heteroarotinoids (Flex-Hets) convey anti-cancer properties in A2780 ovarian cancer cells.
    Bioorganic & medicinal chemistry, 2020, 01-01, Volume: 28, Issue:1

    Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Chromans; Female; Humans

2020
DUOXA1-mediated ROS production promotes cisplatin resistance by activating ATR-Chk1 pathway in ovarian cancer.
    Cancer letters, 2018, 08-01, Volume: 428

    Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Ataxia Telangiectasia Mutated Protein

2018
Activity of oxygen-versus sulfur-containing analogs of the Flex-Het anticancer agent SHetA2.
    European journal of medicinal chemistry, 2018, Oct-05, Volume: 158

    Topics: Antineoplastic Agents; Cell Line, Tumor; Chromans; Female; HSP70 Heat-Shock Proteins; Humans; Molecu

2018
Checkpoint kinase inhibitor AZD7762 overcomes cisplatin resistance in clear cell carcinoma of the ovary.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2014, Volume: 24, Issue:1

    Topics: Adenocarcinoma, Clear Cell; Animals; Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Drug Resist

2014
Chk1 inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers.
    BMC cancer, 2014, Aug-07, Volume: 14

    Topics: Benzodiazepinones; Biomarkers, Tumor; Cell Line, Tumor; Checkpoint Kinase 1; Cisplatin; Deoxycytidin

2014
Synthesis of flexible sulfur-containing heteroarotinoids that induce apoptosis and reactive oxygen species with discrimination between malignant and benign cells.
    Journal of medicinal chemistry, 2004, Feb-12, Volume: 47, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Cell Division; Cell Line, Tumor; Computer Simulation; Drug Screeni

2004
In vitro evaluation of the novel chemotherapeutic agents U-73,975, U-77,779, and U-80,244 in gynecologic cancer cell lines.
    Cancer investigation, 1993, Volume: 11, Issue:3

    Topics: Adenosine Triphosphate; Antineoplastic Agents; Benzofurans; Cisplatin; Cyclohexanecarboxylic Acids;

1993
Biokinetics of the monoclonal antibodies MOv 18, OV 185 and OV 197 labelled with 125I according to the m-MeATE method or the Iodogen method in nude mice with ovarian cancer xenografts.
    Acta oncologica (Stockholm, Sweden), 1999, Volume: 38, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Benzoates; Female; Humans; Indicators and Reagents; Iodine Radioiso

1999
Radioiodinated antibody targeting of the HER-2/neu oncoprotein: effects of labeling method on cellular processing and tissue distribution.
    Nuclear medicine and biology, 1999, Volume: 26, Issue:7

    Topics: Animals; Antibodies, Monoclonal; Cellobiose; Female; Humans; Immunoconjugates; Iodine Radioisotopes;

1999
Optimal quality (131)I-monoclonal antibodies on high-dose labeling in a large reaction volume and temporarily coating the antibody with IODO-GEN.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2001, Volume: 42, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Carrier Proteins; Female; Folate Receptors, GPI-Anchored; Indicator

2001
The charge heterogeneity of soluble human galactosyltransferases isolated from milk, amniotic fluid and malignant ascites.
    European journal of biochemistry, 1979, Feb-01, Volume: 93, Issue:3

    Topics: Amino Acids; Amniotic Fluid; Ascites; Female; Galactosyltransferases; Humans; Hydrogen-Ion Concentra

1979
Time dependence of the selective modulation of cisplatin-induced nephrotoxicity by WR2721 in the mouse.
    Cancer research, 1992, Apr-15, Volume: 52, Issue:8

    Topics: Amifostine; Animals; Cisplatin; Drug Administration Schedule; Female; Kidney; Liver; Male; Mannitol;

1992
The study of antibodies and antigens dissociated from the immune complexes extracted from ovarian carcinoma ascitic fluid.
    Gynecologic oncology, 1985, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Antibodies, Neoplasm; Antigen-Antibody Complex; Antigens, Neoplasm; Ascitic Fluid; C

1985
Multiple carcinogenic effects of the ethylnitrosourea precursors ethylurea and sodium nitrite in hamsters.
    Cancer research, 1974, Volume: 34, Issue:12

    Topics: Age Factors; Animals; Carcinogens; Carcinoma, Squamous Cell; Cricetinae; Female; Liver Neoplasms; Ma

1974
The biochemical diagnosis of ovarian cancer.
    American journal of obstetrics and gynecology, 1973, Jul-15, Volume: 116, Issue:6

    Topics: Adenocarcinoma; Ascitic Fluid; Aspartate Aminotransferases; Bilirubin; Calcium; Cholesterol; Cystade

1973
[Induction of genital cancer in pregnant rats].
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:7

    Topics: Abdominal Neoplasms; Adenocarcinoma; Animals; Carcinoma, Papillary; Carcinoma, Squamous Cell; Female

1969
Gene action in the human haptoglobins. 3. Isolation of the alpha-chains as single gene products. Isolation, molecular weight, and amino acid composition of alpha and beta chains.
    Canadian journal of biochemistry, 1970, Volume: 48, Issue:1

    Topics: Acetamides; Alkylation; Amino Acids; Anhydrides; Ascitic Fluid; Carcinoma; Chemical Phenomena; Chemi

1970