urea has been researched along with Obesity in 156 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the use of the [14C]-sodium bicarbonate/urea technique to measure the change in total energy expenditure after weight loss and a period of weight maintenance." | 9.12 | Use of [14C]-sodium bicarbonate/urea to measure total energy expenditure in overweight men and women before and after low calorie diet induced weight loss. ( Bellon, M; Clifton, PM; Kirkwood, I; Luscombe, ND; Tsopelas, C; Wittert, GA, 2006) |
| "Leptin, the product of the obese gene, is an adipocyte-secreted protein hormone playing a key role in the progression of obesity and hepatic steatosis." | 7.80 | Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis. ( Chen, J; Chen, L; Liang, X; Ma, L; Pei, H; Ran, Y; Wang, G, 2014) |
| "Measurement of urinary electrolytes and urea revealed that an osmotic diuresis induced by urea derived principally by breakdown of endogenous protein was causative." | 7.79 | Severe hypernatremia from a urea-induced diuresis due to body protein wasting in an insulin-resistant type 2 diabetic patient. ( Anderson, A; Barrett, EJ, 2013) |
| "1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea 14a (AR9281), a potent and selective soluble epoxide hydrolase inhibitor, was recently tested in a phase 2a clinical setting for its effectiveness in reducing blood pressure and improving insulin resistance in pre-diabetic patients." | 7.77 | 1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia. ( Aavula, BR; Anandan, SK; Cases, S; Chen, D; Cheng, Y; Do, ZN; Gless, R; Hammock, BD; Jones, PD; MacIntyre, DE; Mehra, U; Patel, DV; Sabry, J; Tran, V; Vincelette, J; Wang, YX; Waszczuk, J; Webb, HK; Whitcomb, R; White, K; Wong, KR; Zhang, LN, 2011) |
| " Substituted phenyl biaryl urea derivatives were synthesized and evaluated as MCH-R1 antagonists for the treatment of obesity." | 7.73 | Biaryl ureas as potent and orally efficacious melanin concentrating hormone receptor 1 antagonists for the treatment of obesity. ( Clader, JW; Cook, J; Farley, C; Graziano, M; Greenlee, WJ; Hawes, B; Kowalski, TJ; McBriar, MD; O'neill, K; Palani, A; Shapiro, S; Spar, B; van Heek, M; Weig, B, 2005) |
| "The effect of gender and degree of obesity on the size indicators V, used to normalize urea clearance (Kt/Vur), and body surface area (BSA), used to normalize creatinine clearance (Ccr), in peritoneal dialysis was studied by: (1) mathematical comparison of the formulae used to estimate V (Watson and Hume) with the Dubois formula used to estimate BSA in peritoneal dialysis; and (2) comparison of percent deviation of BSA (delta BSA%) and V (delta V%) from ideal weight estimates in 933 clearance studies performed in actual patients (555 in men and 378 in women on continuous ambulatory peritoneal dialysis)." | 7.70 | Gender, degree of obesity, and discrepancy between urea and creatinine clearance in peritoneal dialysis. ( Malhotra, D; Murata, GH; Tzamaloukas, AH, 1998) |
| "Treatment of genetically obese rats with oleoyl-estrone in liposomes (Merlin-2) results in sustained loss of body weight-mainly lipid, sparing protein-for up to 28 d, essentially preventing further increase in body weight and accumulation of lipid and protein." | 7.69 | Effect of the slimming agent oleoyl-estrone in liposomes on the body weight of Zucker obese rats. ( Alemany, M; Balada, F; Estruch, J; Fernández-López, JA; Grasa, MM; Remesar, X; Sanchis, D; Virgili, J, 1997) |
| "The activities of pathways for the biosynthesis of hippurate, urea and pyrimidines in hepatocytes isolated from lean livers were compared with those from three sources of fatty liver: a) the genetically obese Zucker rat, b) Sprague-Dawley rats fed a diet deficient in choline and inositol, and c) Sprague-Dawley rats fed a diet supplemented with orotic acid." | 7.67 | Biosynthesis of hippurate, urea and pyrimidines in the fatty liver: studies with rats fed orotic acid or a diet deficient in choline and inositol, and with genetically obese (Zucker) rats. ( Maswoswe, SM; Tremblay, GC, 1989) |
| "0]hexyl urea series with particular emphasis on structure-activity relationships and optimization of receptor occupancy, measured both in vitro and via an ex vivo binding assay following an oral dosing regimen." | 5.33 | Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas. ( Clader, JW; Cook, J; Cox, K; Farley, C; Greenlee, WJ; Guzik, H; Hawes, BE; Kowalski, TJ; McBriar, MD; O'neill, K; Palani, A; Paruchova, J; Shapiro, S; Spar, BD; Weig, B; Weston, DJ; Xu, R, 2006) |
| " Furthermore, glycine could be linked to metabolic health and insulin sensitivity through the betaine osmolyte." | 5.22 | Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance. ( Astrup, A; Carayol, J; Charon, C; Fazelzadeh, P; Hager, J; Lefebvre, G; Matone, A; Morine, M; Saris, WH; Scott-Boyer, MP; Valsesia, A; Vervoort, J, 2016) |
| "The aim of this study was to evaluate the use of the [14C]-sodium bicarbonate/urea technique to measure the change in total energy expenditure after weight loss and a period of weight maintenance." | 5.12 | Use of [14C]-sodium bicarbonate/urea to measure total energy expenditure in overweight men and women before and after low calorie diet induced weight loss. ( Bellon, M; Clifton, PM; Kirkwood, I; Luscombe, ND; Tsopelas, C; Wittert, GA, 2006) |
| "7MJ/d very low energy diet (VLED) from those of a tryptophan- and methionine-supplemented hydrolyzed collagen VLED, in obesity." | 5.08 | Whole-body protein turnover in obese subjects during two very low energy diets of differing amino acid composition. ( Gougeon, R; Marliss, EB; Pencharz, PB, 1995) |
| " This review provides an overview of 5-HT receptor pharmacology and discusses two recent 5-HT receptor subtype-selective drugs, lorcaserin and pimavanserin, which target the 5HT2C and 5HT2A receptors and provide new treatments for obesity and Parkinson's disease psychosis, respectively." | 4.89 | Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs. ( Meltzer, HY; Roth, BL, 2013) |
| " Body weight, body mass index (BMI), body condition score (BCS), SAP, serum SDMA, urea, and creatinine were evaluated." | 4.12 | Renal resistive index in obese and non‑obese cats. ( Bueno de Souza, F; Canevese Rahal, S; Chalfun Guimaraes-Okamoto, PT; Frey Belotta, A; Gomes Lourenço, ML; Mamprim, MJ; Melchert, A; Peruch Bonatelli, S; Rodrigues Ramos, PR; Salgueiro Geraldes, S; Volpi Gonçalves, N, 2022) |
| "We recently showed that the functional capacity for ureagenesis is deficient in non-alcoholic fatty liver disease (NAFLD) patients." | 3.91 | Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion. ( Eriksen, PL; Heebøll, S; Knop, FK; Rigbolt, K; Suppli, MP; Sørensen, M; Thomsen, KL; Veidal, SS; Vilstrup, H, 2019) |
| " Hematocrit, urea, creatinine and microalbuminuria were analyzed, after which the HUGE formula was applied." | 3.81 | The H.U.G.E. Formula (Hematocrit, Urea, Sex) for Screening Chronic Kidney Disease (CKD) in an Age-Stratified General Population. ( Felix, FJ; Fernandez-Berges, D; Lozano, L; Macías, JF; Miranda, I; Robles, NR, 2015) |
| "Leptin, the product of the obese gene, is an adipocyte-secreted protein hormone playing a key role in the progression of obesity and hepatic steatosis." | 3.80 | Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis. ( Chen, J; Chen, L; Liang, X; Ma, L; Pei, H; Ran, Y; Wang, G, 2014) |
| "Measurement of urinary electrolytes and urea revealed that an osmotic diuresis induced by urea derived principally by breakdown of endogenous protein was causative." | 3.79 | Severe hypernatremia from a urea-induced diuresis due to body protein wasting in an insulin-resistant type 2 diabetic patient. ( Anderson, A; Barrett, EJ, 2013) |
| "1-(1-Acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea 14a (AR9281), a potent and selective soluble epoxide hydrolase inhibitor, was recently tested in a phase 2a clinical setting for its effectiveness in reducing blood pressure and improving insulin resistance in pre-diabetic patients." | 3.77 | 1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia. ( Aavula, BR; Anandan, SK; Cases, S; Chen, D; Cheng, Y; Do, ZN; Gless, R; Hammock, BD; Jones, PD; MacIntyre, DE; Mehra, U; Patel, DV; Sabry, J; Tran, V; Vincelette, J; Wang, YX; Waszczuk, J; Webb, HK; Whitcomb, R; White, K; Wong, KR; Zhang, LN, 2011) |
| " In the sub-chronic study, the effect of CS-extract and GLB (at the above doses) on body weight (BW), plasma glucose, insulin, TC, LDL-cholesterol, HDL-cholesterol, TG, urea and creatinine was determined in normal and OHH rats; insulin resistance (IR as HOMA-IR), atherosclerotic and cardioprotective indices were calculated." | 3.77 | Hypoglycemic and hypolipidemic effects of Coriandrum sativum L. in Meriones shawi rats. ( Aissaoui, A; Israili, ZH; Lyoussi, B; Zizi, S, 2011) |
| " Substituted phenyl biaryl urea derivatives were synthesized and evaluated as MCH-R1 antagonists for the treatment of obesity." | 3.73 | Biaryl ureas as potent and orally efficacious melanin concentrating hormone receptor 1 antagonists for the treatment of obesity. ( Clader, JW; Cook, J; Farley, C; Graziano, M; Greenlee, WJ; Hawes, B; Kowalski, TJ; McBriar, MD; O'neill, K; Palani, A; Shapiro, S; Spar, B; van Heek, M; Weig, B, 2005) |
| ") produced hypophagia, a loss of body weight and adiposity, and decreased plasma leptin levels in DIO mice, and hypophagia and reduced weight gain in Lep(ob/ob) mice." | 3.73 | Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice. ( Clader, J; Cook, J; Del Vecchio, RA; Farley, C; Fried, S; Ghibaudi, L; Guzik, H; Hawes, BE; Hwa, J; Kowalski, TJ; McBriar, M; O'Neill, K; Spar, BD; Weig, B, 2006) |
| "The effect of gender and degree of obesity on the size indicators V, used to normalize urea clearance (Kt/Vur), and body surface area (BSA), used to normalize creatinine clearance (Ccr), in peritoneal dialysis was studied by: (1) mathematical comparison of the formulae used to estimate V (Watson and Hume) with the Dubois formula used to estimate BSA in peritoneal dialysis; and (2) comparison of percent deviation of BSA (delta BSA%) and V (delta V%) from ideal weight estimates in 933 clearance studies performed in actual patients (555 in men and 378 in women on continuous ambulatory peritoneal dialysis)." | 3.70 | Gender, degree of obesity, and discrepancy between urea and creatinine clearance in peritoneal dialysis. ( Malhotra, D; Murata, GH; Tzamaloukas, AH, 1998) |
| "Treatment of genetically obese rats with oleoyl-estrone in liposomes (Merlin-2) results in sustained loss of body weight-mainly lipid, sparing protein-for up to 28 d, essentially preventing further increase in body weight and accumulation of lipid and protein." | 3.69 | Effect of the slimming agent oleoyl-estrone in liposomes on the body weight of Zucker obese rats. ( Alemany, M; Balada, F; Estruch, J; Fernández-López, JA; Grasa, MM; Remesar, X; Sanchis, D; Virgili, J, 1997) |
| " Dexfenfluramine (dF), a serotonin releaser and reuptake inhibitor, was used to investigate changes in food intake, body weight development, energy expenditure, respiratory quotient, and substrate oxidation rates for 12 days." | 3.69 | Energy expenditure and substrate oxidation rates of obese rats during a 12-day treatment with dexfenfluramine. ( Aust, L; Boschmann, M; Frenz, U; Noack, R, 1996) |
| " Urinary excretion rates of calcium, sodium, chloride, potassium, urinary calcium/creatinine index, the fractional excretion of sodium, potassium and uric acid, the creatinine clearance and serum values of creatinine, urea, uric acid, electrolytes, total proteins, parathormone (intact molecule), plasma renin activity, aldosterone, glucose, and insulin (fasting and after an oral glucose load) were performed in every patient and control subject." | 3.69 | Urinary calcium excretion in treated and untreated essential hypertension. ( Navarro-Antolin, J; Orte, L; Ortuño, J; Quereda, C; Sabater, J; Villafruela, JJ, 1996) |
| " Daily urinary urea excretion and body weight loss were studied before and during 21 days of fasting." | 3.67 | Effect of fasting on monosodium glutamate-obese rats. ( Andrade, IS; Dolnikoff, MS; Marmo, MR; Ribeiro, EB, 1989) |
| "The activities of pathways for the biosynthesis of hippurate, urea and pyrimidines in hepatocytes isolated from lean livers were compared with those from three sources of fatty liver: a) the genetically obese Zucker rat, b) Sprague-Dawley rats fed a diet deficient in choline and inositol, and c) Sprague-Dawley rats fed a diet supplemented with orotic acid." | 3.67 | Biosynthesis of hippurate, urea and pyrimidines in the fatty liver: studies with rats fed orotic acid or a diet deficient in choline and inositol, and with genetically obese (Zucker) rats. ( Maswoswe, SM; Tremblay, GC, 1989) |
| " By measuring the brain function using computer period analysis of cerebral biopotentials, dose-efficacy relations were found (in the range of 25-75 mcg) which suggest the bioavailability of LHM at the CNS level." | 2.64 | Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram. ( Akpinar, S; Herrmann, WM; Itil, TM, 1975) |
| "In time, HIP rats developed cardiac hypertrophy and left-ventricular dilation." | 1.40 | Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model. ( Chiamvimonvat, N; Despa, F; Despa, S; Dong, H; Hammock, BD; Harris, TR; Li, N; Margulies, KB; Sharma, S; Taegtmeyer, H, 2014) |
| "It suggests that the HFS diet-induced hyperinsulinemia is responsible for the decrease in the circulating levels of urea, creatinine, and many amino acids, despite an increase in serum glucose levels." | 1.39 | Diet-induced hyperinsulinemia differentially affects glucose and protein metabolism: a high-throughput metabolomic approach in rats. ( de la Garza, AL; Etxeberria, U; Martínez, JA; Milagro, FI, 2013) |
| "We report the discovery of piperazine urea based compound 1, a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist." | 1.37 | Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. ( Bakshi, RK; Cashen, DE; Chen, AS; Chen, HY; Fong, TM; Guo, L; He, S; Hong, Q; Liu, J; MacIntyre, DE; MacNeil, T; Martin, WJ; Miller, RR; Nargund, RP; Palucki, BL; Park, MK; Peng, Q; Pollard, PG; Sebhat, IK; Stearns, RA; Strack, AM; Tamvakopoulos, C; Tang, R; Weinberg, DH; Wyvratt, MJ; Ye, Z, 2011) |
| "His prerenal acute renal failure resolved when diuretics were stopped and the high urea:creatinine ratio was diagnostic." | 1.37 | Management of diuretic treatment: a challenge in the obese patient. ( Jespersen, B; Lassen, CK, 2011) |
| "0]hexyl urea series with particular emphasis on structure-activity relationships and optimization of receptor occupancy, measured both in vitro and via an ex vivo binding assay following an oral dosing regimen." | 1.33 | Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas. ( Clader, JW; Cook, J; Cox, K; Farley, C; Greenlee, WJ; Guzik, H; Hawes, BE; Kowalski, TJ; McBriar, MD; O'neill, K; Palani, A; Paruchova, J; Shapiro, S; Spar, BD; Weig, B; Weston, DJ; Xu, R, 2006) |
| "Body weight was also reduced in OM rats 1d after injection of SB-334867 but not in the S5B rats." | 1.33 | Effect of a selective OX1R antagonist on food intake and body weight in two strains of rats that differ in susceptibility to dietary-induced obesity. ( Bray, GA; Ishii, Y; Mendoza, T; Stasi, LP; Upton, N; White, CL; York, DA, 2005) |
| "Degree of obesity was classified by the ratio of body weight (W) to desired weight (DW) at the first clearance study." | 1.31 | Small solute clearances and nutrition indices in obese patients on continuous peritoneal dialysis. ( Hoffman, RM; Murata, GH; Servilla, KS; Tzamaloukas, AH, 2002) |
| " In this study, the anti-obesity effects of SB-334867-A were determined in genetically obese (ob/ob) mice dosed with SB-334867-A (30 mg/kg, i." | 1.31 | Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice. ( Arch, JR; Cawthorne, MA; Chapman, H; Clapham, JC; Haynes, AC; Moore, GB; Tadayyon, M; Taylor, C, 2002) |
| "Urea kinetics were determined from the excretion of [15N15N]urea in urine over a period of 48 h following a single oral dose of [15N15N]urea, in nine lean and nine obese women and in seven light and seven heavy males while they were consuming their habitual diets." | 1.30 | Urea kinetics varies in Jamaican women and men in relation to adiposity, lean body mass and protein intake. ( Child, SC; Forrester, T; Jackson, AA; Persaud, C; Reid, M; Soares, MJ, 1997) |
| "Except for development of hepatic lipidosis, cats appeared to tolerate the fast without other adverse effect." | 1.29 | Experimental induction of hepatic lipidosis in cats. ( Biourge, VC; Groff, JM; Kirk, CA; Madeiros, VA; Morris, JG; Munn, RJ; Nyland, TG; Rogers, QR, 1994) |
| "Urea levels were highest in controls, and lowest in cafeteria rats fed from day 30, a consequence of the different setting of nitrogen sparing induced by the timing of initiation of cafeteria feeding." | 1.29 | Long-term effects of cafeteria diet feeding on young Wistar rats. ( Alemany, M; Arola, L; Salvadó, J; Segués, T, 1994) |
| "Urea N excretion was comparable in both groups and was unaffected by bicarbonate." | 1.28 | Effects of sodium bicarbonate on nitrogen metabolism and ketone bodies during very low energy protein diets in obese subjects. ( Gougeon-Reyburn, R; Marliss, EB, 1989) |
| "Initial body weight was 124." | 1.27 | Weight loss and metabolic changes of morbidly obese patients after gastric partitioning operation. ( Moody, FG; Tsoi, CM; Westenskow, DR, 1984) |
| "In addition to the hyperinsulinemia previously reported to occur in nonhyperphagic VMH-lesioned rats, this study showed an increased glucagon secretion from perfused pancreases of these animals." | 1.26 | Nitrogen handling in adult hypothalamic obese rats. ( Hustvedt, BE; Jeanrenaud, B; Karakash, C; Rohner-Jeanrenaud, F, 1980) |
| " Comparisons were made: 1) between results obtained with single (S) and repeated (R) oral dosage of tracer; and 2) between urea and ammonia as end products." | 1.26 | Protein turnover in man measured with 15N: comparison of end products and dose regimes. ( Garlick, PJ; Golden, MH; Waterlow, JC, 1978) |
| "Total starvation is effective for acute weight reduction in obesity." | 1.26 | [Complications in null-diet]. ( Mordasini, R; Oster, P; Raetzer, H; Schellenberg, B; Schlierf, G, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 63 (40.38) | 18.7374 |
| 1990's | 19 (12.18) | 18.2507 |
| 2000's | 26 (16.67) | 29.6817 |
| 2010's | 37 (23.72) | 24.3611 |
| 2020's | 11 (7.05) | 2.80 |
| Authors | Studies |
|---|---|
| Kaviani, A | 1 |
| Khansari Nejad, N | 1 |
| Akour, A | 1 |
| AlMuhaissen, SA | 1 |
| Nusair, MB | 1 |
| Al-Tammemi, AB | 1 |
| Mahmoud, NN | 1 |
| Jalouqa, S | 1 |
| Alrawashdeh, MN | 1 |
| Shanahan, JP | 1 |
| Moore, CM | 1 |
| Kampf, JW | 1 |
| Szymczak, NK | 1 |
| Guo, J | 1 |
| Wang, H | 1 |
| Luo, Y | 1 |
| An, H | 1 |
| Zhang, Z | 2 |
| Liu, G | 1 |
| Li, J | 1 |
| Metcalfe, GD | 1 |
| Smith, TW | 1 |
| Hippler, M | 1 |
| Ayala Izurieta, JE | 1 |
| Márquez, CO | 1 |
| García, VJ | 1 |
| Jara Santillán, CA | 1 |
| Sisti, JM | 1 |
| Pasqualotto, N | 1 |
| Van Wittenberghe, S | 1 |
| Delegido, J | 1 |
| Kubo, Y | 1 |
| Kitagawa, Y | 1 |
| Miyazaki, T | 1 |
| Sohda, M | 1 |
| Yamaji, T | 1 |
| Sakai, M | 1 |
| Saeki, H | 1 |
| Nemoto, K | 1 |
| Oyama, T | 2 |
| Muto, M | 1 |
| Takeuchi, H | 1 |
| Toh, Y | 1 |
| Matsubara, H | 1 |
| Mano, M | 1 |
| Kono, K | 1 |
| Kato, K | 1 |
| Yoshida, M | 1 |
| Kawakubo, H | 1 |
| Booka, E | 1 |
| Yamatsuji, T | 1 |
| Kato, H | 1 |
| Ito, Y | 1 |
| Ishikawa, H | 1 |
| Ishihara, R | 1 |
| Tsushima, T | 1 |
| Kawachi, H | 1 |
| Kojima, T | 1 |
| Kuribayashi, S | 1 |
| Makino, T | 1 |
| Matsuda, S | 1 |
| Doki, Y | 1 |
| Ma, P | 1 |
| Tang, X | 1 |
| Zhang, L | 2 |
| Wang, X | 1 |
| Wang, W | 1 |
| Zhang, X | 2 |
| Wang, S | 2 |
| Zhou, N | 1 |
| Dodd, J | 1 |
| Jordan, R | 1 |
| Makhlina, M | 1 |
| Pesco Koplowitz, L | 1 |
| Koplowitz, B | 1 |
| Barnett, K | 1 |
| Yang, WH | 1 |
| Spana, C | 1 |
| Buchanan, SW | 1 |
| Mafa-Attoye, T | 1 |
| Dunfield, K | 1 |
| Thevathasan, NV | 1 |
| Isaac, ME | 1 |
| Wu, X | 2 |
| Huang, JW | 1 |
| Su, BK | 1 |
| Yuan, L | 1 |
| Zheng, WQ | 1 |
| Zhang, H | 2 |
| Zheng, YX | 1 |
| Zhu, W | 1 |
| Chou, PT | 1 |
| Manso, AP | 1 |
| De Morais, DC | 1 |
| Yamamoto, K | 1 |
| Owen, G | 1 |
| de Carvalho, RM | 1 |
| Palma-Dibb, RG | 1 |
| Brown, JC | 1 |
| Yang, S | 1 |
| Mire, EF | 1 |
| Miele, L | 1 |
| Ochoa, A | 1 |
| Zabaleta, J | 1 |
| Katzmarzyk, PT | 1 |
| Moi, CT | 1 |
| Bhowmick, S | 1 |
| Qureshi, M | 1 |
| Wang, K | 1 |
| Feng, B | 1 |
| Yang, Y | 1 |
| Chen, Y | 1 |
| Wang, Y | 2 |
| Yang, L | 1 |
| Jiang, K | 1 |
| James, TD | 1 |
| Chaturvedi, V | 1 |
| Postiglione, WM | 1 |
| Chakraborty, RD | 1 |
| Yu, B | 1 |
| Tabiś, W | 1 |
| Hameed, S | 1 |
| Biniskos, N | 1 |
| Jacobson, A | 1 |
| Zhou, H | 1 |
| Greven, M | 1 |
| Ferry, VE | 1 |
| Leighton, C | 1 |
| Wu, F | 1 |
| Lei, H | 1 |
| Chen, G | 1 |
| Chen, C | 1 |
| Song, Y | 1 |
| Cao, Z | 1 |
| Zhang, C | 2 |
| Zhou, J | 1 |
| Lu, Y | 1 |
| Pappone, C | 1 |
| Santinelli, V | 1 |
| Mecarocci, V | 1 |
| Tondi, L | 1 |
| Ciconte, G | 1 |
| Manguso, F | 1 |
| Sturla, F | 1 |
| Vicedomini, G | 1 |
| Micaglio, E | 1 |
| Anastasia, L | 1 |
| Pica, S | 1 |
| Camporeale, A | 1 |
| Lombardi, M | 1 |
| Shieh, PB | 1 |
| Elfring, G | 1 |
| Trifillis, P | 1 |
| Santos, C | 1 |
| Peltz, SW | 1 |
| Parsons, JA | 1 |
| Apkon, S | 1 |
| Darras, BT | 1 |
| Campbell, C | 1 |
| McDonald, CM | 1 |
| Galaviz, KI | 1 |
| Shah, NS | 1 |
| Gutierrez, M | 1 |
| Collins, LF | 1 |
| Lahiri, CD | 1 |
| Moran, CA | 1 |
| Szabo, B | 1 |
| Sumitani, J | 1 |
| Rhodes, J | 1 |
| Marconi, VC | 1 |
| Nguyen, ML | 1 |
| Cantos, VD | 1 |
| Armstrong, WS | 1 |
| Colasanti, JA | 1 |
| Akiu, M | 1 |
| Tsuji, T | 1 |
| Iida, K | 1 |
| Sogawa, Y | 1 |
| Terayama, K | 1 |
| Yokoyama, M | 1 |
| Tanaka, J | 1 |
| Asano, D | 1 |
| Honda, T | 1 |
| Sakurai, K | 1 |
| Pinkerton, AB | 1 |
| Nakamura, T | 1 |
| Bean, C | 1 |
| Audano, M | 1 |
| Varanita, T | 1 |
| Favaretto, F | 1 |
| Medaglia, M | 1 |
| Gerdol, M | 1 |
| Pernas, L | 1 |
| Stasi, F | 1 |
| Giacomello, M | 1 |
| Herkenne, S | 1 |
| Muniandy, M | 1 |
| Heinonen, S | 1 |
| Cazaly, E | 1 |
| Ollikainen, M | 1 |
| Milan, G | 1 |
| Pallavicini, A | 1 |
| Pietiläinen, KH | 1 |
| Vettor, R | 1 |
| Mitro, N | 1 |
| Scorrano, L | 1 |
| Fuglsang-Nielsen, R | 1 |
| Rakvaag, E | 1 |
| Vestergaard, P | 1 |
| Hermansen, K | 1 |
| Gregersen, S | 1 |
| Starup-Linde, J | 1 |
| Othman, MS | 1 |
| Khaled, AM | 1 |
| Aleid, GM | 1 |
| Fareid, MA | 1 |
| Hameed, RA | 1 |
| Abdelfattah, MS | 1 |
| Aldin, DE | 1 |
| Moneim, AEA | 1 |
| Rodrigues, GU | 1 |
| Bueno Campos Canella, PR | 1 |
| de Cássia Dos Santos, R | 1 |
| Razolli, DS | 1 |
| Bueno de Souza, F | 1 |
| Volpi Gonçalves, N | 1 |
| Peruch Bonatelli, S | 1 |
| Frey Belotta, A | 1 |
| Salgueiro Geraldes, S | 1 |
| Mamprim, MJ | 1 |
| Chalfun Guimaraes-Okamoto, PT | 1 |
| Gomes Lourenço, ML | 1 |
| Rodrigues Ramos, PR | 1 |
| Canevese Rahal, S | 1 |
| Melchert, A | 1 |
| Huang, XF | 1 |
| He, Q | 1 |
| Shi, HH | 1 |
| Hu, HP | 1 |
| Lu, L | 1 |
| Huang, RM | 1 |
| Zhang, XY | 1 |
| Xu, YQ | 1 |
| Cialiè Rosso, M | 1 |
| Stilo, F | 1 |
| Squara, S | 1 |
| Liberto, E | 1 |
| Mai, S | 1 |
| Mele, C | 1 |
| Marzullo, P | 1 |
| Aimaretti, G | 1 |
| Reichenbach, SE | 1 |
| Collino, M | 1 |
| Bicchi, C | 1 |
| Cordero, C | 1 |
| Ephraim, RKD | 1 |
| Asamoah, CA | 1 |
| Abaka-Yawson, A | 1 |
| Kwadzokpui, PK | 1 |
| Adusei, S | 1 |
| Zaman, GS | 1 |
| Abohashrh, M | 1 |
| Ahmad, I | 2 |
| Dera, AA | 1 |
| Alshahrani, MS | 1 |
| Alam, MM | 1 |
| Mahmood, SE | 1 |
| Mansuri, N | 1 |
| Irfan, S | 1 |
| Zaman, FA | 1 |
| Humphries, PS | 1 |
| Bersot, R | 1 |
| Kincaid, J | 1 |
| Mabery, E | 1 |
| McCluskie, K | 1 |
| Park, T | 1 |
| Renner, T | 1 |
| Riegler, E | 1 |
| Steinfeld, T | 1 |
| Turtle, ED | 1 |
| Wei, ZL | 1 |
| Willis, E | 1 |
| Møller, G | 1 |
| Rikardt Andersen, J | 1 |
| Ritz, C | 1 |
| P Silvestre, M | 1 |
| Navas-Carretero, S | 1 |
| Jalo, E | 1 |
| Christensen, P | 1 |
| Simpson, E | 1 |
| Taylor, M | 1 |
| Martinez, JA | 2 |
| Macdonald, I | 1 |
| Swindell, N | 1 |
| Mackintosh, KA | 1 |
| Stratton, G | 1 |
| Fogelholm, M | 1 |
| Larsen, TM | 1 |
| Poppitt, SD | 1 |
| Dragsted, LO | 1 |
| Raben, A | 1 |
| Margolis, LM | 1 |
| Ceglia, L | 1 |
| Rivas, DA | 1 |
| Dawson-Hughes, B | 1 |
| Fielding, RA | 1 |
| Isabelle, SA | 1 |
| Ahmed-Ben, M | 1 |
| Benoit, C | 1 |
| Dominique, D | 1 |
| Jérémie, D | 1 |
| Noureddine, H | 1 |
| Carole, M | 1 |
| Estelle, PG | 1 |
| Didier, R | 1 |
| Sergio, P | 1 |
| Di Leva, FS | 1 |
| Festa, C | 1 |
| Carino, A | 1 |
| De Marino, S | 1 |
| Marchianò, S | 1 |
| Di Marino, D | 1 |
| Finamore, C | 1 |
| Monti, MC | 1 |
| Zampella, A | 1 |
| Fiorucci, S | 1 |
| Limongelli, V | 1 |
| Eriksen, PL | 1 |
| Vilstrup, H | 1 |
| Rigbolt, K | 1 |
| Suppli, MP | 1 |
| Sørensen, M | 1 |
| Heebøll, S | 1 |
| Veidal, SS | 1 |
| Knop, FK | 1 |
| Thomsen, KL | 1 |
| Anderson, A | 1 |
| Barrett, EJ | 1 |
| Koletzko, B | 1 |
| Beyer, J | 1 |
| Brands, B | 1 |
| Demmelmair, H | 1 |
| Grote, V | 1 |
| Haile, G | 1 |
| Gruszfeld, D | 1 |
| Rzehak, P | 1 |
| Socha, P | 1 |
| Weber, M | 1 |
| Gao, Z | 2 |
| Hurst, WJ | 2 |
| Guillot, E | 2 |
| Czechtizky, W | 2 |
| Lukasczyk, U | 2 |
| Nagorny, R | 2 |
| Pruniaux, MP | 2 |
| Schwink, L | 2 |
| Sanchez, JA | 2 |
| Stengelin, S | 2 |
| Tang, L | 2 |
| Winkler, I | 2 |
| Hendrix, JA | 2 |
| George, PG | 2 |
| Yang, SM | 1 |
| Tang, Y | 1 |
| Zhang, R | 1 |
| Lu, H | 1 |
| Kuo, GH | 1 |
| Gaul, MD | 1 |
| Li, Y | 1 |
| Ho, G | 1 |
| Conway, JG | 1 |
| Liang, Y | 1 |
| Lenhard, JM | 1 |
| Demarest, KT | 1 |
| Murray, WV | 1 |
| Teske, JA | 1 |
| Billington, CJ | 1 |
| Kotz, CM | 1 |
| Meltzer, HY | 1 |
| Roth, BL | 1 |
| Mediavilla, C | 1 |
| Risco, S | 1 |
| Liang, X | 1 |
| Pei, H | 1 |
| Ma, L | 1 |
| Ran, Y | 1 |
| Chen, J | 1 |
| Wang, G | 1 |
| Chen, L | 1 |
| Despa, S | 1 |
| Sharma, S | 1 |
| Harris, TR | 1 |
| Dong, H | 1 |
| Li, N | 1 |
| Chiamvimonvat, N | 1 |
| Taegtmeyer, H | 1 |
| Margulies, KB | 1 |
| Hammock, BD | 2 |
| Despa, F | 1 |
| Roche, C | 1 |
| Besnier, M | 1 |
| Cassel, R | 1 |
| Harouki, N | 1 |
| Coquerel, D | 1 |
| Guerrot, D | 1 |
| Nicol, L | 1 |
| Loizon, E | 1 |
| Remy-Jouet, I | 1 |
| Morisseau, C | 1 |
| Mulder, P | 1 |
| Ouvrard-Pascaud, A | 1 |
| Madec, AM | 1 |
| Richard, V | 1 |
| Bellien, J | 1 |
| Teixeira, TG | 1 |
| Tibana, RA | 1 |
| Nascimento, DD | 1 |
| de Sousa, NM | 1 |
| de Souza, VC | 1 |
| Vieira, DC | 1 |
| Nóbrega, OT | 1 |
| de Almeida, JA | 1 |
| Navalta, J | 1 |
| Prestes, J | 1 |
| Robles, NR | 1 |
| Felix, FJ | 1 |
| Lozano, L | 1 |
| Miranda, I | 1 |
| Fernandez-Berges, D | 1 |
| Macías, JF | 1 |
| Zhou, JJ | 1 |
| Yuan, F | 1 |
| Zhang, Y | 1 |
| Li, DP | 1 |
| Peng, XY | 1 |
| Guo, FF | 1 |
| Sun, XR | 1 |
| Gong, YL | 1 |
| Xu, L | 1 |
| Linz, B | 1 |
| Hohl, M | 1 |
| Reil, JC | 1 |
| Böhm, M | 1 |
| Linz, D | 1 |
| White, PA | 1 |
| Araújo, JM | 1 |
| Cercato, LM | 1 |
| Souza, LA | 1 |
| Barbosa, AP | 1 |
| Quintans-Junior, LJ | 1 |
| Machado, UF | 1 |
| Camargo, EA | 1 |
| Brito, LC | 1 |
| Santos, MR | 1 |
| Grapsa, E | 1 |
| Pipili, C | 1 |
| Angelopoulos, E | 1 |
| Pantelias, K | 1 |
| Kapetanaki, A | 1 |
| Deda, E | 1 |
| Kiousi, E | 1 |
| Tzanatos, H | 1 |
| Matone, A | 1 |
| Scott-Boyer, MP | 1 |
| Carayol, J | 1 |
| Fazelzadeh, P | 1 |
| Lefebvre, G | 1 |
| Valsesia, A | 1 |
| Charon, C | 1 |
| Vervoort, J | 1 |
| Astrup, A | 1 |
| Saris, WH | 1 |
| Morine, M | 1 |
| Hager, J | 1 |
| Bak, AM | 1 |
| Møller, AB | 1 |
| Vendelbo, MH | 1 |
| Nielsen, TS | 1 |
| Viggers, R | 1 |
| Rungby, J | 1 |
| Pedersen, SB | 1 |
| Jørgensen, JO | 2 |
| Jessen, N | 1 |
| Møller, N | 2 |
| Berglund, S | 1 |
| Egner, BJ | 1 |
| Gradén, H | 1 |
| Gradén, J | 1 |
| Morgan, DG | 1 |
| Inghardt, T | 1 |
| Giordanetto, F | 1 |
| Stepien, M | 1 |
| Gaudichon, C | 1 |
| Azzout-Marniche, D | 1 |
| Fromentin, G | 1 |
| Tomé, D | 1 |
| Even, P | 1 |
| Zhang, LN | 2 |
| Vincelette, J | 2 |
| Chen, D | 2 |
| Gless, RD | 1 |
| Anandan, SK | 2 |
| Rubanyi, GM | 1 |
| Webb, HK | 2 |
| MacIntyre, DE | 3 |
| Wang, YX | 2 |
| Aavula, BR | 1 |
| Cases, S | 1 |
| Cheng, Y | 1 |
| Do, ZN | 1 |
| Mehra, U | 1 |
| Tran, V | 1 |
| Waszczuk, J | 1 |
| White, K | 1 |
| Wong, KR | 1 |
| Jones, PD | 1 |
| Patel, DV | 1 |
| Whitcomb, R | 1 |
| Sabry, J | 1 |
| Gless, R | 1 |
| Lassen, CK | 1 |
| Jespersen, B | 1 |
| Hong, Q | 1 |
| Bakshi, RK | 1 |
| Palucki, BL | 1 |
| Park, MK | 1 |
| Ye, Z | 1 |
| He, S | 1 |
| Pollard, PG | 1 |
| Sebhat, IK | 1 |
| Liu, J | 1 |
| Guo, L | 1 |
| Cashen, DE | 1 |
| Martin, WJ | 1 |
| Weinberg, DH | 1 |
| MacNeil, T | 1 |
| Tang, R | 1 |
| Tamvakopoulos, C | 1 |
| Peng, Q | 1 |
| Miller, RR | 1 |
| Stearns, RA | 1 |
| Chen, HY | 1 |
| Chen, AS | 1 |
| Strack, AM | 1 |
| Fong, TM | 1 |
| Wyvratt, MJ | 1 |
| Nargund, RP | 1 |
| Aissaoui, A | 1 |
| Zizi, S | 1 |
| Israili, ZH | 1 |
| Lyoussi, B | 1 |
| Motiwala, H | 1 |
| Kandre, S | 1 |
| Birar, V | 1 |
| Kadam, KS | 1 |
| Rodge, A | 1 |
| Jadhav, RD | 1 |
| Mahesh Kumar Reddy, M | 1 |
| Brahma, MK | 1 |
| Deshmukh, NJ | 1 |
| Dixit, A | 1 |
| Doshi, L | 1 |
| Gupte, A | 1 |
| Gangopadhyay, AK | 1 |
| Vishwakarma, RA | 1 |
| Srinivasan, S | 1 |
| Sharma, M | 1 |
| Nemmani, KV | 1 |
| Sharma, R | 1 |
| Hussain, TA | 1 |
| Mathew, TC | 1 |
| Dashti, AA | 1 |
| Asfar, S | 1 |
| Al-Zaid, N | 1 |
| Dashti, HM | 1 |
| Fernández-Fígares, I | 1 |
| Lachica, M | 1 |
| Martín, A | 1 |
| Nieto, R | 1 |
| González-Valero, L | 1 |
| Rodríguez-López, JM | 1 |
| Aguilera, JF | 1 |
| Mao, X | 1 |
| Zeng, X | 1 |
| Huang, Z | 1 |
| Wang, J | 1 |
| Qiao, S | 1 |
| Etxeberria, U | 1 |
| de la Garza, AL | 1 |
| Milagro, FI | 1 |
| Tzamaloukas, AH | 2 |
| Murata, GH | 2 |
| Servilla, KS | 1 |
| Hoffman, RM | 1 |
| Gibney, ER | 2 |
| Murgatroyd, P | 1 |
| Wright, A | 1 |
| Jebb, S | 1 |
| Elia, M | 2 |
| Faber, P | 1 |
| Johnstone, AM | 1 |
| Stubbs, RJ | 1 |
| Roger, PL | 1 |
| Milne, E | 1 |
| Buchan, W | 1 |
| Lobley, GE | 1 |
| SPRAGUE, RG | 1 |
| SCHWARZ, F | 2 |
| DER KINDEREN, PJ | 1 |
| JICK, H | 1 |
| KAMM, DE | 1 |
| SNYDER, JG | 1 |
| MORRISON, RS | 1 |
| CHALMERS, TC | 1 |
| RAPOPORT, A | 1 |
| FROM, GL | 1 |
| HUSDAN, H | 1 |
| Jordão, AA | 1 |
| Bellucci, AD | 1 |
| Dutra de Oliveira, JE | 1 |
| Sérgio Marchini, J | 1 |
| McBriar, MD | 3 |
| Guzik, H | 3 |
| Xu, R | 2 |
| Paruchova, J | 2 |
| Li, S | 1 |
| Palani, A | 3 |
| Clader, JW | 3 |
| Greenlee, WJ | 4 |
| Hawes, BE | 3 |
| Kowalski, TJ | 4 |
| O'Neill, K | 4 |
| Spar, B | 2 |
| Weig, B | 4 |
| White, CL | 1 |
| Ishii, Y | 1 |
| Mendoza, T | 1 |
| Upton, N | 1 |
| Stasi, LP | 1 |
| Bray, GA | 2 |
| York, DA | 1 |
| Souers, AJ | 1 |
| Gao, J | 2 |
| Wodka, D | 1 |
| Judd, AS | 1 |
| Mulhern, MM | 1 |
| Napier, JJ | 1 |
| Brune, ME | 1 |
| Bush, EN | 1 |
| Brodjian, SJ | 1 |
| Dayton, BD | 1 |
| Shapiro, R | 1 |
| Hernandez, LE | 1 |
| Marsh, KC | 1 |
| Sham, HL | 1 |
| Collins, CA | 1 |
| Kym, PR | 1 |
| Shapiro, S | 2 |
| Farley, C | 4 |
| Cook, J | 4 |
| van Heek, M | 2 |
| Graziano, M | 1 |
| Hawes, B | 1 |
| Nørrelund, H | 2 |
| Spar, BD | 2 |
| Ghibaudi, L | 2 |
| Fried, S | 1 |
| Del Vecchio, RA | 1 |
| McBriar, M | 1 |
| Clader, J | 1 |
| Hwa, J | 1 |
| Cox, K | 1 |
| Weston, DJ | 1 |
| Khosroshahi, HT | 1 |
| Shoja, MM | 1 |
| Kok, P | 1 |
| Roelfsema, F | 1 |
| Frölich, M | 1 |
| van Pelt, J | 1 |
| Stokkel, MP | 1 |
| Meinders, AE | 2 |
| Pijl, H | 1 |
| Luscombe, ND | 1 |
| Tsopelas, C | 1 |
| Bellon, M | 1 |
| Clifton, PM | 1 |
| Kirkwood, I | 1 |
| Wittert, GA | 1 |
| Remer, T | 1 |
| Berkemeyer, S | 1 |
| Rylander, R | 1 |
| Vormann, J | 1 |
| Madsen, L | 1 |
| Pedersen, LM | 1 |
| Liaset, B | 1 |
| Ma, T | 1 |
| Petersen, RK | 1 |
| van den Berg, S | 1 |
| Pan, J | 1 |
| Müller-Decker, K | 1 |
| Dülsner, ED | 1 |
| Kleemann, R | 1 |
| Kooistra, T | 1 |
| Døskeland, SO | 1 |
| Kristiansen, K | 1 |
| Li, G | 1 |
| Stamford, AW | 1 |
| Huang, Y | 1 |
| Cheng, KC | 1 |
| Guzzi, M | 1 |
| Hwa, JJ | 1 |
| Kelly, J | 1 |
| Mullins, D | 1 |
| Parker, EM | 1 |
| Wainhaus, S | 1 |
| Teixeira Nunes, F | 1 |
| de Campos, G | 1 |
| Xavier de Paula, SM | 1 |
| Merhi, VA | 1 |
| Portero-McLellan, KC | 1 |
| da Motta, DG | 1 |
| de Oliveira, MR | 1 |
| Fern, EB | 1 |
| Waterlow, JC | 3 |
| Tsoi, CM | 1 |
| Westenskow, DR | 1 |
| Moody, FG | 1 |
| Coronas, R | 1 |
| Duran, S | 1 |
| Gomez, P | 1 |
| Romero, H | 1 |
| Sastre, A | 1 |
| Clemmons, DR | 1 |
| Klibanski, A | 1 |
| Underwood, LE | 1 |
| McArthur, JW | 1 |
| Ridgway, EC | 1 |
| Beitins, IZ | 1 |
| Van Wyk, JJ | 1 |
| Karakash, C | 1 |
| Rohner-Jeanrenaud, F | 1 |
| Hustvedt, BE | 1 |
| Jeanrenaud, B | 1 |
| Winterer, J | 1 |
| Bistrian, BR | 1 |
| Bilmazes, C | 2 |
| Blackburn, GL | 1 |
| Young, VR | 4 |
| Kleinknecht, C | 1 |
| Gros, F | 1 |
| Jean, G | 1 |
| Broyer, M | 1 |
| Malcolm, R | 1 |
| O'Neil, PM | 1 |
| Hirsch, AA | 1 |
| Currey, HS | 1 |
| Moskowitz, G | 1 |
| Goodman, MN | 1 |
| Larsen, PR | 1 |
| Kaplan, MM | 1 |
| Aoki, TT | 3 |
| Ruderman, NB | 1 |
| Mitch, WE | 1 |
| Walser, M | 3 |
| Sapir, DG | 4 |
| Vazquez, JA | 1 |
| Kazi, U | 1 |
| Madani, N | 1 |
| Biourge, VC | 1 |
| Groff, JM | 1 |
| Munn, RJ | 1 |
| Kirk, CA | 1 |
| Nyland, TG | 1 |
| Madeiros, VA | 1 |
| Morris, JG | 1 |
| Rogers, QR | 1 |
| Segués, T | 1 |
| Salvadó, J | 1 |
| Arola, L | 2 |
| Alemany, M | 5 |
| Gougeon, R | 2 |
| Pencharz, PB | 1 |
| Marliss, EB | 4 |
| Boschmann, M | 1 |
| Aust, L | 1 |
| Frenz, U | 1 |
| Noack, R | 1 |
| Byerley, LO | 1 |
| Heber, D | 1 |
| Quereda, C | 1 |
| Orte, L | 1 |
| Sabater, J | 1 |
| Navarro-Antolin, J | 1 |
| Villafruela, JJ | 1 |
| Ortuño, J | 1 |
| Child, SC | 1 |
| Soares, MJ | 1 |
| Reid, M | 1 |
| Persaud, C | 1 |
| Forrester, T | 1 |
| Jackson, AA | 1 |
| Balada, F | 1 |
| Sanchis, D | 1 |
| Grasa, MM | 2 |
| Virgili, J | 1 |
| Estruch, J | 2 |
| Fernández-López, JA | 2 |
| Remesar, X | 5 |
| Malhotra, D | 1 |
| Adán, C | 1 |
| Cabot, C | 1 |
| Vilà, R | 1 |
| Masanés, RM | 1 |
| Esteve, M | 3 |
| Herrero, MC | 1 |
| Bladé, C | 1 |
| Børglum, J | 1 |
| Richelsen, B | 1 |
| Nair, KS | 1 |
| Christiansen, JS | 1 |
| Styhler, K | 1 |
| Morais, JA | 1 |
| Jones, PJ | 1 |
| Haynes, AC | 3 |
| Jackson, B | 1 |
| Chapman, H | 2 |
| Tadayyon, M | 2 |
| Johns, A | 1 |
| Porter, RA | 1 |
| Arch, JR | 3 |
| Weisshaar, E | 1 |
| Bonnekoh, B | 1 |
| Franke, I | 1 |
| Gollnick, H | 1 |
| Karpe, F | 1 |
| Fielding, BA | 1 |
| Ilic, V | 1 |
| Humphreys, SM | 1 |
| Frayn, KN | 1 |
| Taylor, C | 1 |
| Moore, GB | 1 |
| Cawthorne, MA | 1 |
| Clapham, JC | 1 |
| Smart, D | 1 |
| Williams, G | 1 |
| Munro, HN | 2 |
| Schürch, PM | 1 |
| Reinke, A | 1 |
| Hollmann, W | 1 |
| Förster, H | 1 |
| Huth, K | 1 |
| Koch, E | 1 |
| Tunali, G | 1 |
| Shetty, PS | 1 |
| Jung, RT | 1 |
| James, WP | 1 |
| Golden, MH | 1 |
| Garlick, PJ | 1 |
| Schulz, E | 2 |
| Schräpler, P | 2 |
| Oster, P | 1 |
| Mordasini, R | 1 |
| Raetzer, H | 1 |
| Schellenberg, B | 1 |
| Schlierf, G | 1 |
| Itil, TM | 1 |
| Herrmann, WM | 1 |
| Akpinar, S | 1 |
| Kawaguchi, T | 1 |
| Matsushita, H | 1 |
| Ebner, H | 1 |
| Müller, WA | 2 |
| Brennan, MF | 2 |
| Cahill, GF | 2 |
| Rabast, U | 1 |
| Kasper, H | 1 |
| Schönborn, J | 1 |
| Richards, P | 1 |
| Rafecas, I | 2 |
| Betrán, MA | 1 |
| Estornell, E | 1 |
| Barber, T | 2 |
| Cabo, J | 2 |
| Pond, WG | 1 |
| Ellis, KJ | 1 |
| Schoknecht, P | 1 |
| Lund, PE | 1 |
| Berts, A | 1 |
| Hellman, B | 1 |
| Picó, C | 1 |
| Pons, A | 1 |
| Gianotti, M | 2 |
| Palou, A | 2 |
| Paczek, L | 1 |
| Teschner, M | 1 |
| Schaefer, RM | 1 |
| Heidland, A | 1 |
| Roca, P | 1 |
| Gougeon-Reyburn, R | 1 |
| Seng, G | 1 |
| Galgoti, C | 1 |
| Louisy, P | 1 |
| Toussain, P | 1 |
| Drouin, P | 1 |
| Debry, G | 1 |
| Ribeiro, EB | 1 |
| Marmo, MR | 1 |
| Andrade, IS | 1 |
| Dolnikoff, MS | 1 |
| Maswoswe, SM | 1 |
| Tremblay, GC | 1 |
| Wolman, SI | 1 |
| Sheppard, H | 1 |
| Fern, M | 1 |
| Devlin, JT | 1 |
| Horton, ES | 1 |
| Koppeschaar, HP | 1 |
| Viña, JR | 1 |
| Viña, J | 1 |
| Goldman, JK | 1 |
| Schnatz, JD | 1 |
| Bernardis, LL | 1 |
| Frohman, LA | 1 |
| Beloff-Chain, A | 1 |
| Rookledge, KA | 1 |
| Schwartz, H | 1 |
| Jensen, HE | 1 |
| Cuendet, G | 1 |
| Balant, L | 1 |
| Wolheim, CB | 1 |
| Stauffacher, W | 1 |
| Owen, OE | 2 |
| Pozefsky, T | 1 |
| Ahnefeld-Olbertz, S | 1 |
| Rudolfsky, G | 1 |
| Schultis, K | 1 |
| Segers, MJ | 1 |
| Mertens, C | 1 |
| Genuth, SM | 2 |
| Castro, JH | 1 |
| Vertes, V | 1 |
| Lantzsch, W | 1 |
| Seige, K | 1 |
| Corsini, G | 1 |
| Carrai, M | 1 |
| Havenberg, LN | 1 |
| van Stekelenburg, GJ | 1 |
| Stoop, JW | 1 |
| Krom, ML | 1 |
| Bines, JA | 1 |
| Napper, DJ | 1 |
| Jourdan, M | 1 |
| Margen, S | 1 |
| Bradfield, RB | 1 |
| North, KA | 1 |
| Lascelles, D | 1 |
| Coates, P | 1 |
| Hellerström, C | 1 |
| Westman, S | 1 |
| Stork, H | 1 |
| Schmidt, FH | 1 |
| Jackson, WP | 1 |
| Ditschuneit, H | 1 |
| Cheng, JT | 1 |
| Ginsberg, R | 1 |
| Boden, G | 1 |
| Walker, WG | 1 |
| Billich, C | 1 |
| Gallagher, TF | 1 |
| Hoffbrand, AV | 1 |
| Levitan, R | 1 |
| Gallina, DL | 1 |
| Dominguez, JM | 1 |
| Adibi, SA | 1 |
| Welborn, TA | 1 |
| Cumpston, GN | 1 |
| Cullen, KJ | 1 |
| Curnow, DH | 1 |
| McCall, MG | 1 |
| Stenhouse, NS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Whey Protein and Dietary Fibers on Risk Markers of the Metabolic Syndrome and Bone Health[NCT02931630] | 72 participants (Actual) | Interventional | 2016-05-31 | Completed | |||
| Dietary Intervention in Type-2 Diabetics and Pre-Diabetics Emphasizing Personalized Carbohydrate Intake[NCT02519309] | 465 participants (Actual) | Interventional | 2015-08-31 | Completed | |||
| A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma[NCT05119010] | 60 participants (Anticipated) | Interventional | 2023-03-24 | Recruiting | |||
| Open-label, Flexible-dose Adjunctive Bromocriptine for Patients With Schizophrenia and Impaired Glucose Tolerance[NCT03575000] | Phase 4 | 20 participants (Anticipated) | Interventional | 2023-11-01 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for urea and Obesity
| Article | Year |
|---|---|
Topics: Adult; Alcohol Drinking; Ammonia; Animals; Anti-Inflammatory Agents; Area Under Curve; B-Lymphocytes | 2021 |
Obesity contributes to mortality and displays alterations in calcium, urea and hemoglobin levels in SARS-CoV-2 infected individuals.
Topics: Calcium; COVID-19; Humans; Obesity; Observational Studies as Topic; Overweight; SARS-CoV-2; Urea | 2022 |
Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs.
Topics: Benzazepines; Diabetes Mellitus, Type 2; Heart Valve Diseases; Humans; Molecular Structure; Obesity; | 2013 |
[Orexin: clinical and therapeutic implications].
Topics: Animals; Arousal; Azepines; Benzoxazoles; Disease Models, Animal; Drug Evaluation, Preclinical; Feed | 2014 |
Consequences of growth hormone deficiency for intermediary metabolism and effects of replacement.
Topics: Adipose Tissue; Adult; Fasting; Glucose; Hormone Replacement Therapy; Human Growth Hormone; Humans; | 2005 |
Protein turnover, nitrogen balance and rehabilitation.
Topics: Amino Acids; Animals; Child; Convalescence; Dietary Proteins; Fasting; Female; Food; Growth; Humans; | 1983 |
Orexins and the treatment of obesity.
Topics: Animals; Benzoxazoles; Body Weight; Carrier Proteins; Eating; Humans; Intracellular Signaling Peptid | 2002 |
[Carbohydrate-reduced diet and metabolism: about the influence of a 4-weeks isocaloric fat-rich, carbohydrate-reduced diet on body weight and metabolism (author's transl)].
Topics: Adult; Body Weight; Cholesterol; Dietary Carbohydrates; Dietary Fats; Electrolytes; Energy Intake; H | 1979 |
[Possibilities for the determination of fat portion in body weight].
Topics: Adipose Tissue; Antipyrine; Body Composition; Body Water; Body Weight; Densitometry; Ethanol; Extrac | 1974 |
Oral sulphonylureas in the management of diabetes.
Topics: Acetohexamide; Chlorpropamide; Cyclohexanes; Diabetes Mellitus; Endocrine Glands; Glucose Tolerance | 1971 |
15 trials available for urea and Obesity
| Article | Year |
|---|---|
The Effects of 12-Weeks Whey Protein Supplements on Markers of Bone Turnover in Adults With Abdominal Obesity - A
Topics: Adult; Biomarkers; Bone Remodeling; Calcium; Diabetes Mellitus, Type 2; Dietary Fiber; Humans; Insul | 2022 |
The Impact of Body Resistance Training Exercise on Biomedical Profile at High Altitude: A Randomized Controlled Trial.
Topics: Adiponectin; Adult; Blood Glucose; Body Composition; Creatinine; Cross-Sectional Studies; Exercise T | 2021 |
Higher Protein Intake Is Not Associated with Decreased Kidney Function in Pre-Diabetic Older Adults Following a One-Year Intervention-A Preview Sub-Study.
Topics: Aged; Albuminuria; Biomarkers; Creatinine; Diet, High-Protein; Dietary Proteins; Europe; Female; Glo | 2018 |
Pilot Study Examining the Influence of Potassium Bicarbonate Supplementation on Nitrogen Balance and Whole-Body Ammonia and Urea Turnover Following Short-Term Energy Restriction in Older Men.
Topics: Aged; Ammonia; Bicarbonates; Body Mass Index; Diet, Reducing; Dietary Supplements; Energy Intake; Gl | 2018 |
Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance.
Topics: Adult; Ammonia; Betaine; Caloric Restriction; Carbamoyl-Phosphate Synthase (Ammonia); Carbamyl Phosp | 2016 |
Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Caloric Restriction; Creatinine; Diabetes Mellitus, Type 2; D | 2012 |
Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Caloric Restriction; Creatinine; Diabetes Mellitus, Type 2; D | 2012 |
Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Caloric Restriction; Creatinine; Diabetes Mellitus, Type 2; D | 2012 |
Effect of low-calorie versus low-carbohydrate ketogenic diet in type 2 diabetes.
Topics: Adult; Blood Glucose; Body Mass Index; Caloric Restriction; Creatinine; Diabetes Mellitus, Type 2; D | 2012 |
Impact of dietary betaine and conjugated linoleic acid on insulin sensitivity, protein and fat metabolism of obese pigs.
Topics: Analysis of Variance; Animal Nutritional Physiological Phenomena; Animals; Betaine; Dietary Proteins | 2012 |
The effect of rate and extent of weight loss on urea salvage in obese male subjects.
Topics: Adaptation, Physiological; Adult; Diet, Reducing; Energy Metabolism; Humans; Male; Middle Aged; Nitr | 2003 |
Activation of dopamine D2 receptors simultaneously ameliorates various metabolic features of obese women.
Topics: Adult; Blood Glucose; Bromocriptine; Calorimetry, Indirect; Circadian Rhythm; Cross-Over Studies; Do | 2006 |
Use of [14C]-sodium bicarbonate/urea to measure total energy expenditure in overweight men and women before and after low calorie diet induced weight loss.
Topics: Adult; Body Composition; Body Mass Index; Carbon Radioisotopes; Creatinine; Diet, Reducing; Energy I | 2006 |
Protein metabolism during weight reduction with very-low-energy diets: evaluation of the independent effects of protein and carbohydrate on protein sparing.
Topics: 3-Hydroxybutyric Acid; Adult; Amino Acids; Ammonia; Analysis of Variance; Blood Glucose; Body Compos | 1995 |
Whole-body protein turnover in obese subjects during two very low energy diets of differing amino acid composition.
Topics: Adult; Amino Acids; Analysis of Variance; Body Mass Index; Caseins; Collagen; Diet, Protein-Restrict | 1995 |
Effects of growth hormone administration on protein dynamics and substrate metabolism during 4 weeks of dietary restriction in obese women.
Topics: Adult; Amino Acids; Analysis of Variance; Calorimetry, Indirect; Combined Modality Therapy; Dietary | 2000 |
Prediction of psychotropic properties of lisuride hydrogen maleate by quantitative pharmaco-electroencephalogram.
Topics: Adolescent; Adult; Aged; Biological Availability; Child; Child, Preschool; Clinical Trials as Topic; | 1975 |
Metabolic effects of a single administration of growth hormone on lipid and carbohydrate metabolism in normal-weight and obese subjects.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Blood Glucose; Carbohydrates; Cholesterol; Fatty Acids, | 1989 |
131 other studies available for urea and Obesity
| Article | Year |
|---|---|
Discovery of DS68702229 as a Potent, Orally Available NAMPT (Nicotinamide Phosphoribosyltransferase) Activator.
Topics: Animals; Anti-Obesity Agents; Body Weight; Diabetes Mellitus, Type 2; Humans; Male; Mice, Obese; NAD | 2021 |
The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites.
Topics: Adipocytes, Beige; Adipocytes, Brown; Adipocytes, White; Adipose Tissue; Animals; Cyclic AMP Respons | 2021 |
Evaluation of antiobesity and hepatorenal protective activities of Salvia officinalis extracts pre-treatment in high-fat diet-induced obese rats.
Topics: Animals; Antioxidants; Biomarkers; Body Weight; Creatinine; Diet, High-Fat; Flavonoids; Inflammation | 2022 |
Renal resistive index in obese and non‑obese cats.
Topics: Animals; Body Weight; Cats; Female; Kidney; Male; Obesity; Urea | 2022 |
[Mediating effects of obesity and metabolic factors in hyperuricemia and prehypertension].
Topics: Body Mass Index; Cholesterol; Cholesterol, LDL; Creatinine; Humans; Hyperuricemia; Nitrogen; Obesity | 2023 |
Exploring extra dimensions to capture saliva metabolite fingerprints from metabolically healthy and unhealthy obese patients by comprehensive two-dimensional gas chromatography featuring Tandem Ionization mass spectrometry.
Topics: Acetylglucosamine; Algorithms; Amino Acids, Neutral; Chromatography; Chromatography, Gas; Chromatogr | 2021 |
Climate change causes changes in biochemical markers of kidney disease.
Topics: Adult; Blood Pressure; Body Mass Index; Climate Change; Creatinine; Female; Ghana; Glomerular Filtra | 2020 |
Carbazole-containing amides and ureas: Discovery of cryptochrome modulators as antihyperglycemic agents.
Topics: Amides; Animals; Carbazoles; Cryptochromes; Diabetes Mellitus, Experimental; Dose-Response Relations | 2018 |
Profound Changes in Net Energy and Nitrogen Metabolites Fluxes within the Splanchnic Area during Overfeeding of Yucatan Mini Pigs That Remain Euglycemic.
Topics: Adaptation, Physiological; Amino Acids; Animals; Bile; Blood Glucose; Carbohydrate Metabolism; Energ | 2019 |
Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1.
Topics: Bile; Bile Acids and Salts; Diabetes Mellitus, Type 2; HEK293 Cells; Humans; Ligands; Non-alcoholic | 2019 |
Non-alcoholic fatty liver disease alters expression of genes governing hepatic nitrogen conversion.
Topics: Adult; Ammonia; Carbamoyl-Phosphate Synthase (Ammonia); Case-Control Studies; Female; Gene Expressio | 2019 |
Severe hypernatremia from a urea-induced diuresis due to body protein wasting in an insulin-resistant type 2 diabetic patient.
Topics: Diabetes Mellitus, Type 2; Diuresis; Electrolytes; Glucocorticoids; Humans; Hypernatremia; Hypertens | 2013 |
Early influences of nutrition on postnatal growth.
Topics: Amino Acids; Amino Acids, Branched-Chain; Animals; Blood Glucose; Body Mass Index; Breast Feeding; C | 2013 |
Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part I).
Topics: Amides; Animals; Drug Evaluation, Preclinical; HEK293 Cells; Histamine H3 Antagonists; Humans; Macac | 2013 |
Discovery of aryl ureas and aryl amides as potent and selective histamine H3 receptor antagonists for the treatment of obesity (part II).
Topics: Administration, Oral; Amides; Animals; Benzamides; Caco-2 Cells; Drug Evaluation, Preclinical; Drug | 2013 |
4-Bicyclic heteroaryl-piperidine derivatives as potent, orally bioavailable Stearoyl-CoA desaturase-1 (SCD1) inhibitors. Part 1: urea-based analogs.
Topics: Administration, Oral; Animals; Body Weight; Diet; Enzyme Activation; Enzyme Inhibitors; Mice; Mice, | 2013 |
Mechanisms underlying obesity resistance associated with high spontaneous physical activity.
Topics: Age Factors; Animals; Benzazepines; Benzoxazoles; Body Weight; Dopamine Antagonists; Eating; Electro | 2014 |
Synthesis and biological evaluation of novel urea- and guanidine-based derivatives for the treatment of obesity-related hepatic steatosis.
Topics: 3T3-L1 Cells; Animals; Diet, High-Fat; Fatty Liver; Gene Expression Regulation; Guanidine; Humans; L | 2014 |
Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model.
Topics: Adamantane; Animals; Animals, Genetically Modified; Calcium; Cardiomegaly; Diabetes Mellitus, Type 2 | 2014 |
Soluble epoxide hydrolase inhibition improves coronary endothelial function and prevents the development of cardiac alterations in obese insulin-resistant mice.
Topics: Animals; Benzoates; Blood Glucose; Coronary Vessels; Disease Models, Animal; Dose-Response Relations | 2015 |
Endothelial nitric oxide synthase Glu298Asp gene polymorphism influences body composition and biochemical parameters but not the nitric oxide response to eccentric resistance exercise in elderly obese women.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Body Composition; Body Mass Index; Exercise; Femal | 2016 |
The H.U.G.E. Formula (Hematocrit, Urea, Sex) for Screening Chronic Kidney Disease (CKD) in an Age-Stratified General Population.
Topics: Adult; Age Distribution; Age Factors; Aged; Aging; Albuminuria; Anthropometry; Cardiovascular Diseas | 2015 |
Upregulation of orexin receptor in paraventricular nucleus promotes sympathetic outflow in obese Zucker rats.
Topics: Action Potentials; Animals; Benzoxazoles; Blood Pressure; Central Nervous System Agents; Disease Mod | 2015 |
[Effect of orexin-A and orexin-1 receptor antagonist injected into the fourth ventricle of rats on food-intake and spontaneous physical activity].
Topics: Animals; Benzoxazoles; Diet, High-Fat; Eating; Fourth Ventricle; Motor Activity; Naphthyridines; Obe | 2015 |
Inhibition of NHE3-mediated Sodium Absorption in the Gut Reduced Cardiac End-organ Damage Without Deteriorating Renal Function in Obese Spontaneously Hypertensive Rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Genetic Predisposition to | 2016 |
Chrysobalanus icaco L. Leaves Normalizes Insulin Sensitivity and Blood Glucose and Inhibits Weight Gain in High-Fat Diet-Induced Obese Mice.
Topics: Adipose Tissue; Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Blood Gluc | 2016 |
Comparison of creatinine clearance estimates in subgroups based on Body Mass Index and albumin.
Topics: Adult; Aged; Albuminuria; Biomarkers; Body Mass Index; Creatinine; Female; Glomerular Filtration Rat | 2016 |
Differential regulation of lipid and protein metabolism in obese vs. lean subjects before and after a 72-h fast.
Topics: 1-Acylglycerol-3-Phosphate O-Acyltransferase; Adipose Tissue; Adult; Autophagy-Related Protein-1 Hom | 2016 |
Optimization of piperidin-4-yl-urea-containing melanin-concentrating hormone receptor 1 (MCH-R1) antagonists: Reducing hERG-associated liabilities.
Topics: Animal Feed; Animals; Cell Line; Chemistry, Pharmaceutical; Drug Design; ERG1 Potassium Channel; Eth | 2009 |
Postprandial nutrient partitioning but not energy expenditure is modified in growing rats during adaptation to a high-protein diet.
Topics: Adiposity; Animals; Body Temperature Regulation; Calorimetry, Indirect; Dietary Carbohydrates; Dieta | 2010 |
Inhibition of soluble epoxide hydrolase attenuates endothelial dysfunction in animal models of diabetes, obesity and hypertension.
Topics: Adamantane; Administration, Oral; Animals; Aorta; Diabetes Mellitus, Experimental; Diabetes Mellitus | 2011 |
1-(1-acetyl-piperidin-4-yl)-3-adamantan-1-yl-urea (AR9281) as a potent, selective, and orally available soluble epoxide hydrolase inhibitor with efficacy in rodent models of hypertension and dysglycemia.
Topics: Adamantane; Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Blood Glucose; D | 2011 |
Management of diuretic treatment: a challenge in the obese patient.
Topics: Acute Kidney Injury; Aged; Biomarkers; Comorbidity; Creatinine; Diuretics; Drug Overdose; Furosemide | 2011 |
Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist.
Topics: Administration, Oral; Animals; Biological Availability; Disease Models, Animal; Dogs; Drug Evaluatio | 2011 |
Hypoglycemic and hypolipidemic effects of Coriandrum sativum L. in Meriones shawi rats.
Topics: Administration, Oral; Animals; Atherosclerosis; Biomarkers; Blood Glucose; Body Weight; Coriandrum; | 2011 |
Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.
Topics: Animals; Anti-Obesity Agents; Diacylglycerol O-Acyltransferase; Drug Design; Enzyme Inhibitors; Inhi | 2011 |
Leptin and leucine synergistically regulate protein metabolism in C2C12 myotubes and mouse skeletal muscles.
Topics: Animals; Cell Line; Dietary Supplements; Drug Synergism; Leptin; Leucine; Mice; Mice, Knockout; Mice | 2013 |
Diet-induced hyperinsulinemia differentially affects glucose and protein metabolism: a high-throughput metabolomic approach in rats.
Topics: Amino Acids; Animals; Creatinine; Diet, High-Fat; Fatty Acids, Unsaturated; Hyperglycemia; Hyperinsu | 2013 |
Small solute clearances and nutrition indices in obese patients on continuous peritoneal dialysis.
Topics: Anthropometry; Blood Urea Nitrogen; Creatinine; Female; Humans; Male; Middle Aged; Molecular Weight; | 2002 |
Measurement of total energy expenditure in grossly obese women: comparison of the bicarbonate-urea method with whole-body calorimetry and free-living doubly labelled water.
Topics: Adult; Basal Metabolism; Bicarbonates; Body Mass Index; Body Water; Calorimetry, Indirect; Deuterium | 2003 |
INSULIN AND ORAL AGENTS: PRINCIPLES IN THE TREATMENT OF DIABETES.
Topics: Acidosis; Diabetes Mellitus; Drug Tolerance; Glycosuria; Hypoglycemic Agents; Insulin; Minnesota; Ob | 1963 |
METABOLIC OBSERVATIONS DURING THE TREATMENT OF OBESE PATIENTS BY PERIODS OF TOTAL STARVATION.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Basal Metabolism; Blood Chemical Analysis; Blood Glucose; | 1964 |
ON THE CONCENTRATING DEFECT IN CIRRHOSIS OF THE LIVER.
Topics: Alcoholism; Arthritis; Arthritis, Rheumatoid; Coronary Disease; Dehydration; Dermatitis; Diabetes Me | 1964 |
METABOLIC STUDIES IN PROLONGED FASTING. I. INORGANIC METABOLISM AND KIDNEY FUNCTION.
Topics: Acid-Base Equilibrium; Acidosis; Adolescent; Aldosterone; Alkalosis; Basal Metabolism; Body Weight; | 1965 |
Midarm computerized tomography fat, muscle and total areas correlation with nutritional assessment data.
Topics: Adult; Analysis of Variance; Arm; Body Composition; Case-Control Studies; Creatinine; Electric Imped | 2004 |
Discovery of bicycloalkyl urea melanin concentrating hormone receptor antagonists: orally efficacious antiobesity therapeutics.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Biological Availability; Brain; Bridged Bicyclo | 2005 |
Effect of a selective OX1R antagonist on food intake and body weight in two strains of rats that differ in susceptibility to dietary-induced obesity.
Topics: Animals; Benzoxazoles; Body Weight; Diet; Eating; Gene Expression Regulation; Hypothalamus; Male; Na | 2005 |
Synthesis and evaluation of urea-based indazoles as melanin-concentrating hormone receptor 1 antagonists for the treatment of obesity.
Topics: Animals; Indazoles; Mice; Obesity; Receptors, Somatostatin; Structure-Activity Relationship; Urea | 2005 |
Biaryl ureas as potent and orally efficacious melanin concentrating hormone receptor 1 antagonists for the treatment of obesity.
Topics: Administration, Oral; Animals; Body Weight; Calcium; Cells, Cultured; Chronic Disease; Humans; Obesi | 2005 |
Effects of a selective melanin-concentrating hormone 1 receptor antagonist on food intake and energy homeostasis in diet-induced obese mice.
Topics: Adipose Tissue; Administration, Oral; Animals; Binding, Competitive; Body Weight; Brain; CHO Cells; | 2006 |
Discovery of orally efficacious melanin-concentrating hormone receptor-1 antagonists as antiobesity agents. Synthesis, SAR, and biological evaluation of bicyclo[3.1.0]hexyl ureas.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Biological Availability; Body Weight; Brain; CHO | 2006 |
Tubulointerstitial disease and ulcerative colitis.
Topics: Adult; Arthritis, Juvenile; Colitis, Ulcerative; Creatinine; Disease Susceptibility; Dwarfism; Human | 2006 |
Muscularity and adiposity in addition to net acid excretion as predictors of 24-h urinary pH in young adults and elderly.
Topics: Adipose Tissue; Adolescent; Adult; Age Factors; Aged; Aging; Body Mass Index; Creatinine; Cross-Sect | 2007 |
cAMP-dependent signaling regulates the adipogenic effect of n-6 polyunsaturated fatty acids.
Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Animals; Carbohydrates; Cyclic AMP; Fatty Acids, Omega-6; Fa | 2008 |
Discovery of novel orally active ureido NPY Y5 receptor antagonists.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Combinatorial Chemistry Techniques; Dogs; Humans | 2008 |
Dialysis adequacy and nutritional status of hemodialysis patients.
Topics: Adult; Aged; Body Mass Index; Body Size; Cross-Sectional Studies; Female; Humans; Kidney Failure, Ch | 2008 |
Weight loss and metabolic changes of morbidly obese patients after gastric partitioning operation.
Topics: Adipose Tissue; Adult; Basal Metabolism; Body Weight; Energy Metabolism; Female; Humans; Male; Middl | 1984 |
Modified total fasting and obesity: results of a multicentric study.
Topics: Body Weight; Diet, Reducing; Energy Intake; Fasting; Female; Food, Formulated; Humans; Male; Obesity | 1982 |
Reduction of plasma immunoreactive somatomedin C during fasting in humans.
Topics: Adult; Fasting; Food; Humans; Insulin-Like Growth Factor I; Kinetics; Male; Middle Aged; Nitrogen; O | 1981 |
Nitrogen handling in adult hypothalamic obese rats.
Topics: Amino Acids; Animals; Female; Glucagon; Hyperinsulinism; Hypothalamus; Hypothalamus, Middle; Lipid M | 1980 |
Whole body protein turnover, studied with 15N-glycine, and muscle protein breakdown in mildly obese subjects during a protein-sparing diet and a brief total fast.
Topics: Adult; Dietary Proteins; Fasting; Female; Glycine; Humans; Kinetics; Methylhistidines; Muscle Protei | 1980 |
Growth and free amino acids in uremic hyperphagic rats.
Topics: Amino Acids; Amino Acids, Essential; Animals; Body Weight; Creatinine; Energy Intake; Kidney Failure | 1980 |
Taste hedonics and thresholds in obesity.
Topics: Adolescent; Adult; Aging; Female; Humans; Hydrochloric Acid; Obesity; Osmolar Concentration; Sodium | 1980 |
Starvation in the rat. II. Effect of age and obesity on protein sparing and fuel metabolism.
Topics: Aging; Amino Acids; Animals; Blood Glucose; Energy Metabolism; Fatty Acids, Nonesterified; Hormones; | 1980 |
Nitrogen sparing induced by leucine compared with that induced by its keto analogue, alpha-ketoisocaproate, in fasting obese man.
Topics: Adult; Amino Acids; Fasting; Female; Humans; Infusions, Parenteral; Keto Acids; Leucine; Male; Middl | 1981 |
Experimental induction of hepatic lipidosis in cats.
Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Blood Glucose; Body Weight; Cats; Erythrocyte C | 1994 |
Long-term effects of cafeteria diet feeding on young Wistar rats.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Blood Glucose; Body Weight; Diet; Female; Glycerol; Hydroxybu | 1994 |
Energy expenditure and substrate oxidation rates of obese rats during a 12-day treatment with dexfenfluramine.
Topics: Amino Acids; Animals; Blood Glucose; Body Weight; Calorimetry, Indirect; Dose-Response Relationship, | 1996 |
Metabolic effects of triiodothyronine replacement during fasting in obese subjects.
Topics: Adult; Blood Glucose; Fasting; Female; Humans; Leucine; Male; Middle Aged; Nitrogen; Obesity; Oxygen | 1996 |
Urinary calcium excretion in treated and untreated essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aldosterone; Antihypertensive Agents; Benzothiadiazines; Blood G | 1996 |
Urea kinetics varies in Jamaican women and men in relation to adiposity, lean body mass and protein intake.
Topics: Adult; Body Composition; Body Mass Index; Dietary Proteins; Female; Humans; Hydrolysis; Jamaica; Kin | 1997 |
Effect of the slimming agent oleoyl-estrone in liposomes on the body weight of Zucker obese rats.
Topics: Animals; Anti-Obesity Agents; Blood Glucose; Body Composition; Body Weight; Cholesterol; Cohort Stud | 1997 |
Gender, degree of obesity, and discrepancy between urea and creatinine clearance in peritoneal dialysis.
Topics: Analysis of Variance; Body Height; Body Surface Area; Body Water; Body Weight; Creatinine; Female; H | 1998 |
Oleoyl-estrone treatment affects the ponderostat setting differently in lean and obese Zucker rats.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Energy Intake | 1999 |
Ammonium uptake and urea production in hepatocytes from lean and obese Zucker rats.
Topics: Alanine; Animals; Biological Transport, Active; In Vitro Techniques; Liver; Male; Nitrogen; Obesity; | 1999 |
Effects of oral hypoglycemic agents and diet on protein metabolism in type 2 diabetes.
Topics: Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet, Diabetic; Drug Therapy, Combinati | 2000 |
A selective orexin-1 receptor antagonist reduces food consumption in male and female rats.
Topics: Animals; Appetite Depressants; Benzoxazoles; Carrier Proteins; Darkness; Eating; Fasting; Female; In | 2000 |
[Successful symptomatic tazarotene treatment of juvenile acanthosis nigricans of the familial obesity-associated type in insulin resistance].
Topics: Acanthosis Nigricans; Administration, Topical; Child; Diabetes Mellitus; Diabetes Mellitus, Type 2; | 2001 |
Monitoring adipose tissue blood flow in man: a comparison between the (133)xenon washout method and microdialysis.
Topics: Adipose Tissue; Adult; Blood Glucose; Ethanol; Female; Humans; Male; Microdialysis; Middle Aged; Obe | 2002 |
Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice.
Topics: Adipose Tissue, Brown; Animals; Benzoxazoles; Body Composition; Body Weight; Diabetes Mellitus, Type | 2002 |
Urinary excretion of N gamma-methylihistidine (3-methylihistidine): a tool to study metabolic responses in relation to nutrient and hormonal status in health and disease of man.
Topics: Adrenal Glands; Adult; Aged; Aging; Animals; Diet, Vegetarian; Dietary Proteins; Feces; Female; Frac | 1978 |
[Is fenfluramine suitable as a therapeutic principle in obese aged diabetics? (end)].
Topics: Aged; Cholesterol; Diabetes Mellitus; Fenfluramine; Gastric Emptying; Glucose; Humans; Lactates; Obe | 1979 |
The effect of energy restriction on nitrogen balances in obese subjects on varying protein intakes.
Topics: Creatinine; Dietary Proteins; Humans; Nitrogen; Obesity; Urea | 1979 |
Protein turnover in man measured with 15N: comparison of end products and dose regimes.
Topics: Adult; Female; Humans; Infant; Male; Methods; Middle Aged; Nitrogen Radioisotopes; Nutrition Disorde | 1978 |
Nitrogen sparing induced early in starvation by infusion of branched-chain ketoacids.
Topics: Adult; Amino Acids; Creatinine; Fasting; Female; Humans; Keto Acids; Nitrogen; Obesity; Quaternary A | 1977 |
[Changes of kidney function in obese subjects during absolute fasting (author's transl)].
Topics: Adult; Creatinine; Fasting; Female; Humans; Kidney; Kidney Function Tests; Male; Obesity; p-Aminohip | 1977 |
[Complications in null-diet].
Topics: Acetone; Adult; Allopurinol; Arrhythmias, Cardiac; Diet, Reducing; Edema; Female; Humans; Ischemic A | 1977 |
[Transposition of the kidney function in persons with obesity under strict fasting].
Topics: Creatinine; Fasting; Humans; Kidney; Obesity; Urea; Uric Acid | 1976 |
Electrophoretic patterns of serum albumins collected from hereditary obese and diabetic mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Eating; Electrophoresis, Polyacrylamide Gel; Fatty Acids; | 1975 |
[Contact eczema caused by clothing].
Topics: Allergens; Chromates; Clothing; Coloring Agents; Dermatitis, Contact; Formaldehyde; Humans; Hyperhid | 1975 |
Metabolic effects of glucose in brief and prolonged fasted man.
Topics: Acetoacetates; Adolescent; Adult; Amino Acids; Ammonia; Blood Glucose; Fasting; Fatty Acids, Noneste | 1975 |
[Treatment of obesity with low-carbohydrate diets (author's transl)].
Topics: Body Weight; Cholesterol; Diet Therapy; Dietary Carbohydrates; Dietary Fats; Humans; Obesity; Trigly | 1975 |
Editorial: Nitrogen-recycling in uremia: a reappraisal.
Topics: Albumins; Amino Acids; Ammonia; Dietary Proteins; Fasting; Humans; Keto Acids; Nitrogen; Nitrogen Is | 1975 |
Nitrogen balances of lean and obese Zucker rats subjected to a cafeteria diet.
Topics: Absorption; Animals; Body Weight; Dietary Fats; Dietary Proteins; Disease Models, Animal; Energy Int | 1992 |
Nitrogen metabolism in obesity induced by monosodium-L-glutamate in rats.
Topics: Analysis of Variance; Animals; Animals, Newborn; Body Weight; Liver; Male; Nitrogen; Obesity; Organ | 1992 |
Response of blood serum constituents to production of and recovery from a kwashiorkor-like syndrome in the young pig.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubin; Blood P | 1992 |
Stimulation of insulin release by isosmolar addition of permeant molecules.
Topics: 3-O-Methylglucose; Animals; Calcium; Cytoplasmic Granules; Exocytosis; Hot Temperature; Hyperglycemi | 1992 |
Sustained changes in blood alpha amino nitrogen compartmentation during recovery from cafeteria feeding in rats.
Topics: Amino Acids; Animals; Diet; Female; Food; Nitrogen; Obesity; Rats; Rats, Inbred Strains; Starvation; | 1991 |
Intraglomerular fibronectin accumulation and degradation in obese Zucker rats.
Topics: Animals; Blood Glucose; Blood Proteins; Cholesterol; Creatinine; Enzyme-Linked Immunosorbent Assay; | 1991 |
Plasma amino acids of lean and obese Zucker rats subjected to a cafeteria diet after weaning.
Topics: Amino Acids; Animals; Blood Glucose; Body Weight; Diet; Dietary Proteins; Energy Metabolism; Female; | 1991 |
Metabolic response to short term starvation in non-pregnant and late pregnant cafeteria-obese rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Female; Fetal Blood; Glycerol; Hydroxy | 1989 |
Effects of sodium bicarbonate on nitrogen metabolism and ketone bodies during very low energy protein diets in obese subjects.
Topics: Adult; Bicarbonates; Dietary Proteins; Energy Metabolism; Female; Humans; Hydroxybutyrates; Ketone B | 1989 |
Effect of fasting on monosodium glutamate-obese rats.
Topics: Animals; Blood Glucose; Fasting; Glutamates; Lipid Metabolism; Male; Obesity; Rats; Rats, Inbred Str | 1989 |
Biosynthesis of hippurate, urea and pyrimidines in the fatty liver: studies with rats fed orotic acid or a diet deficient in choline and inositol, and with genetically obese (Zucker) rats.
Topics: Ammonium Chloride; Animals; Benzoates; Choline Deficiency; Diet; Fatty Liver; Gluconeogenesis; Hippu | 1989 |
The effect of tri-iodothyronine (T3) on protein turnover and metabolic rate.
Topics: Adult; Ammonia; Body Weight; Creatinine; Diet Therapy; Female; Humans; Metabolism; Obesity; Triiodot | 1985 |
Effects of prior high-intensity exercise on glucose metabolism in normal and insulin-resistant men.
Topics: Adult; Blood Glucose; C-Peptide; Glucose; Glucose Tolerance Test; Glycogen; Glycogen Synthase; Human | 1985 |
Renal concentrating ability in obesity. Effect of modified fasting and the supplementation of T3, sodium chloride and carbohydrate.
Topics: Adult; Creatinine; Dietary Carbohydrates; Fasting; Female; Humans; Kidney Concentrating Ability; Mal | 1985 |
Decreased urea synthesis in cafeteria-diet-induced obesity in the rat.
Topics: Amino Acids; Animals; Body Weight; Diet; Liver; Male; Nitrogen; Obesity; Rats; Rats, Inbred Strains; | 1985 |
Effects of ventromedial hypothalamic destruction in rats with preexisting streptozotocin-induced diabetes.
Topics: Adipose Tissue; Animals; Blood Glucose; Body Height; Body Weight; Diabetes Mellitus; Electrocoagulat | 1972 |
Effect of streptozotocin in genetically obese hyperglycemic mice and their lean litter mates.
Topics: Animals; Anti-Bacterial Agents; Blood Glucose; Body Weight; Diabetes Mellitus; Hyperglycemia; Insuli | 1972 |
Jejuno-ileostomy in the treatment of obesity.
Topics: Acne Vulgaris; Adult; Biopsy; Body Height; Body Weight; Diet, Reducing; Female; Gastric Juice; Gluco | 1973 |
The metabolic response of lean and obese mice to prolonged fasting.
Topics: Adipose Tissue; Amino Acids; Animals; Blood Glucose; Body Weight; Disease Models, Animal; Fasting; G | 1974 |
Nitrogen sparing induced by a mixture of essential amino acids given chiefly as their keto-analogues during prolonged starvation in obese subjects.
Topics: Amino Acids; Female; Humans; Infusions, Parenteral; Isoleucine; Keto Acids; Leucine; Methionine; Nit | 1974 |
[Dietary aspects in the treatment of obesity (author's transl)].
Topics: Blood Glucose; Diabetes Mellitus; Exercise Therapy; Female; Humans; Hypertension; Lipids; Male; Obes | 1974 |
The role of glucagon as a catabolic hormone.
Topics: Alanine; Amino Acids; Ammonia; Carbon Radioisotopes; Fasting; Glucagon; Half-Life; Humans; Obesity; | 1974 |
Psychological and bioclinical CHD risk factors. Quantitative differences between obese, normal and thin subjects.
Topics: Adult; Anxiety; Blood Glucose; Blood Pressure; Body Weight; Cholesterol; Coronary Disease; Depressio | 1974 |
Weight reduction in obesity by outpatient semistarvation.
Topics: Adult; Alanine; Body Weight; Calcium; Diet, Reducing; Evaluation Studies as Topic; Fasting; Female; | 1974 |
[Pathogenesis of clinically primary obesity].
Topics: Adolescent; Adult; Aged; Body Weight; Creatinine; Diet, Reducing; Fatty Acids, Nonesterified; Female | 1972 |
Effects of oral alanine administration in fasting obese subjects.
Topics: Administration, Oral; Adult; Alanine; Blood Glucose; Female; Gluconeogenesis; Humans; Hydroxybutyrat | 1973 |
Potential use of 3-methylhistidine excretion as an index of progressive reduction in muscle protein catabolism during starvation.
Topics: Adult; Creatinine; Female; Humans; Male; Methylhistidines; Muscle Proteins; Muscles; Nitrogen; Obesi | 1973 |
Age dependency of mean values in blood and blood serum of healthy Dutch school children between 4 and 13 years of age.
Topics: Adolescent; Aging; Blood; Blood Proteins; Body Height; Body Surface Area; Body Weight; Calcium; Chil | 1973 |
The effect of urea on the intake of straw by fat cows and thin cows.
Topics: Animals; Appetite Regulation; Cattle; Eating; Female; Nitrogen; Obesity; Thinness; Urea | 1973 |
Protein-sparing effect in obese women fed low calorie diets.
Topics: Adult; Basal Metabolism; Body Weight; Creatinine; Diet, Reducing; Dietary Carbohydrates; Dietary Fat | 1974 |
The mechanisms by which sodium excretion is increased during a fast but reduced on subsequent carbohydrate feeding.
Topics: Acetoacetates; Body Weight; Calcium; Chlorides; Dietary Carbohydrates; Fasting; Feces; Female; Human | 1974 |
[Effect of blood sugar decreasing sulfonylureas on the in vitro metabolism of glucose and amino acids in the beta-cells of the pancreas in mice].
Topics: Alanine; Amino Acids; Animals; Arginine; Carbon Isotopes; Depression, Chemical; Female; Glucose; Hyp | 1969 |
[Physiopathology of obesity and its treatment with prolonged fasting].
Topics: Acid-Base Equilibrium; Ammonia; Basal Metabolism; Diet, Reducing; Electrolytes; Fasting; Fatty Acids | 1972 |
The effect of carbohydrates on ammonium and ketoacid excretion during starvation.
Topics: Adolescent; Adult; Ammonia; Bicarbonates; Body Height; Body Weight; Dietary Carbohydrates; Fasting; | 1972 |
Absorptive capacity of the jejunum of obese and lean subjects: effect of fasting.
Topics: Adult; Alkaline Phosphatase; Biopsy; Body Weight; Fasting; Female; Folic Acid; Glucose; Glucosidases | 1972 |
Human utilization of urea nitrogen in low calorie diets.
Topics: Adult; Amino Acids; Animals; Basal Metabolism; Body Weight; Diet, Reducing; Dietary Carbohydrates; F | 1971 |
Alteration in the urinary excretion rate of amino acids and nitrogen by dietary means in obese and normal human subjects.
Topics: Adult; Alanine; Amino Acids; Creatinine; Female; Humans; Isoleucine; Leucine; Male; Nitrogen; Obesit | 1971 |
The prevalence of coronary heart disease and associated factors in an Australian rural community.
Topics: Adult; Age Factors; Aged; Australia; Blood Glucose; Blood Pressure; Cholesterol; Coronary Disease; E | 1969 |