urea has been researched along with Neuronal Ceroid-Lipofuscinoses in 2 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Neuronal Ceroid-Lipofuscinoses: A group of severe neurodegenerative diseases characterized by intracellular accumulation of autofluorescent wax-like lipid materials (CEROID; LIPOFUSCIN) in neurons. There are several subtypes based on mutations of the various genes, time of disease onset, and severity of the neurological defects such as progressive DEMENTIA; SEIZURES; and visual failure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The treatment of Batten disease cells with NAC for 48 h attenuated activities of the urea cycle and of DNA repair, as indicated by the substantially decreased expression levels of carbamoyl phosphate synthetase 1, 8-oxoguanine DNA glycosylase 1 and DNA polymerase beta proteins compared with untreated Batten cells." | 1.38 | N-acetylcysteine normalizes the urea cycle and DNA repair in cells from patients with Batten disease. ( Heo, TH; Kim, JB; Kim, SJ; Lim, N, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chan, CH | 1 |
| Ramirez-Montealegre, D | 1 |
| Pearce, DA | 1 |
| Kim, JB | 1 |
| Lim, N | 1 |
| Kim, SJ | 1 |
| Heo, TH | 1 |
2 other studies available for urea and Neuronal Ceroid-Lipofuscinoses
| Article | Year |
|---|---|
Altered arginine metabolism in the central nervous system (CNS) of the Cln3-/- mouse model of juvenile Batten disease.
Topics: Animals; Arginine; Brain; Cationic Amino Acid Transporter 1; Cells, Cultured; Citrulline; Disease Mo | 2009 |
N-acetylcysteine normalizes the urea cycle and DNA repair in cells from patients with Batten disease.
Topics: Acetylcysteine; Blotting, Western; Carbamoyl-Phosphate Synthase (Ammonia); Cell Line; DNA Glycosylas | 2012 |