urea has been researched along with Neuralgia in 8 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mechanical allodynia and thermal hyperalgesia were evaluated using von Frey filaments and a thermal stimulus." | 1.56 | Chemical stimulation of the lateral hypothalamus induces antiallodynic and anti-thermal hyperalgesic effects in animal model of neuropathic pain: Involvement of orexin receptors in the spinal cord. ( Haghparast, A; Kashfi, K; Manaheji, H; Salehi, S, 2020) |
| "TrkA is a target for chronic pain treatment due to the central position of the nerve growth factor (NGF)/TrkA pathway in nociception." | 1.43 | Evaluation of WO2015042088 A1 - a novel urea-based scaffold for TrkA inhibition. ( Bernard-Gauthier, V; Schirrmacher, R, 2016) |
| "Peripheral nerve injury leads to neuropathic pain, but the underlying mechanisms are not clear." | 1.36 | Spinal nerve ligation in mouse upregulates TRPV1 heat function in injured IB4-positive nociceptors. ( Hogan, QH; Honore, P; Stucky, CL; Vilceanu, D, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, WJ | 1 |
| Wang, YY | 1 |
| Zhao, Y | 1 |
| Jia, H | 1 |
| Tang, JS | 1 |
| Huo, FQ | 1 |
| Liu, H | 1 |
| Salehi, S | 1 |
| Kashfi, K | 1 |
| Manaheji, H | 1 |
| Haghparast, A | 1 |
| Matsuura, W | 1 |
| Nakamoto, K | 1 |
| Tokuyama, S | 1 |
| Wardach, J | 1 |
| Wagner, M | 1 |
| Jeong, Y | 1 |
| Holden, JE | 1 |
| Bernard-Gauthier, V | 1 |
| Schirrmacher, R | 1 |
| Vilceanu, D | 1 |
| Honore, P | 1 |
| Hogan, QH | 1 |
| Stucky, CL | 1 |
| Mazzardo-Martins, L | 1 |
| Martins, DF | 1 |
| Stramosk, J | 1 |
| Cidral-Filho, FJ | 1 |
| Santos, AR | 1 |
| Yamamoto, T | 1 |
| Saito, O | 1 |
| Aoe, T | 1 |
| Bartolozzi, A | 1 |
| Sarva, J | 1 |
| Zhou, J | 1 |
| Kozikowski, A | 1 |
| Wroblewska, B | 1 |
| Bzdega, T | 1 |
| Neale, JH | 1 |
8 other studies available for urea and Neuralgia
| Article | Year |
|---|---|
Involvement of 5-HT2A, 5-HT2B and 5-HT2C receptors in mediating the ventrolateral orbital cortex-induced antiallodynia in a rat model of neuropathic pain.
Topics: Animals; Hyperalgesia; Indoles; Male; Neuralgia; Prefrontal Cortex; Rats, Sprague-Dawley; Receptor, | 2020 |
Chemical stimulation of the lateral hypothalamus induces antiallodynic and anti-thermal hyperalgesic effects in animal model of neuropathic pain: Involvement of orexin receptors in the spinal cord.
Topics: Animals; Benzoxazoles; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Hot Temp | 2020 |
Involvement of descending pain control system regulated by orexin receptor signaling in the induction of central post-stroke pain in mice.
Topics: Adrenergic alpha-2 Receptor Antagonists; Animals; Benzoxazoles; Brain; Brain Ischemia; Hyperalgesia; | 2020 |
Lateral Hypothalamic Stimulation Reduces Hyperalgesia Through Spinally Descending Orexin-A Neurons in Neuropathic Pain.
Topics: Analgesics, Non-Narcotic; Animals; Benzoxazoles; Carbachol; Female; Hyperalgesia; Hypothalamic Area, | 2016 |
Evaluation of WO2015042088 A1 - a novel urea-based scaffold for TrkA inhibition.
Topics: Chronic Pain; Drug Design; Humans; Inflammation; Inhibitory Concentration 50; Neoplasms; Neuralgia; | 2016 |
Spinal nerve ligation in mouse upregulates TRPV1 heat function in injured IB4-positive nociceptors.
Topics: Animals; Cells, Cultured; Disease Models, Animal; Ganglia, Spinal; Hot Temperature; Isoquinolines; L | 2010 |
Glycogen synthase kinase 3-specific inhibitor AR-A014418 decreases neuropathic pain in mice: evidence for the mechanisms of action.
Topics: Analgesics; Animals; Arginine; Cytokines; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Hyperalgesi | 2012 |
Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carrageenan; Cells, Cultured; Cerebellum; Cricetinae; Cricetul | 2007 |