urea and Neural Tube Defects studies

urea and Neural Tube Defects

urea has been researched along with Neural Tube Defects in 3 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Neural Tube Defects: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)

Research Excerpts

Excerpt	Relevance	Reference
" VCU was mainly eliminated by metabolism with a half-life of 2 h."	1.36	Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative. ( Bialer, M; Finnell, RH; Schurig, V; Shimshoni, JA; Wlodarczyk, B; Yagen, B, 2010)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (66.67)	29.6817
2010's	1 (33.33)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

0 (0.00)

18.7374

1990's

0 (0.00)

18.2507

2000's

2 (66.67)

29.6817

2010's

1 (33.33)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Shimshoni, JA	3
Yagen, B	3
Wlodarczyk, B	2
Finnell, RH	2
Schurig, V	1
Bialer, M	3
Okada, A	1
Noyori, H	1
Fujiwara, M	1
Pessah, N	1

Studies

Shimshoni, JA

Yagen, B

Wlodarczyk, B

Finnell, RH

Schurig, V

Bialer, M

Okada, A

Noyori, H

Fujiwara, M

Pessah, N

Other Studies

3 other studies available for urea and Neural Tube Defects

Article	Year
Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative. Epilepsia, 2010, Volume: 51, Issue:3 Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug	2010
Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice. Birth defects research. Part B, Developmental and reproductive toxicology, 2009, Volume: 86, Issue:5 Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bone and Bones; Deep Sedation; Differential T	2009
Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid. Epilepsia, 2008, Volume: 49, Issue:7 Topics: Animals; Anticonvulsants; Behavior, Animal; Electrodes, Implanted; Half-Life; Hippocampus; Kindling,	2008

Article

Year

Evaluation of stereoselective anticonvulsant, teratogenic, and pharmacokinetic profile of valnoctylurea (capuride): a chiral stereoisomer of valproic acid urea derivative.

Epilepsia, 2010, Volume: 51, Issue:3

Topics: Animals; Anticonvulsants; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug

2010

Anticonvulsant profile and teratogenic evaluation of potent new analogues of a valproic acid urea derivative in NMRI mice.

Birth defects research. Part B, Developmental and reproductive toxicology, 2009, Volume: 86, Issue:5

Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Bone and Bones; Deep Sedation; Differential T

2009

Anticonvulsant profile and teratogenicity of 3,3-dimethylbutanoylurea: a potential for a second generation drug to valproic acid.

Epilepsia, 2008, Volume: 49, Issue:7

Topics: Animals; Anticonvulsants; Behavior, Animal; Electrodes, Implanted; Half-Life; Hippocampus; Kindling,

2008