urea has been researched along with Morphine Abuse in 11 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our results indicated that the inhibition of OXR1 significantly reduces the development of morphine dependence and behavioral signs elicited by the administration of naloxone in morphine-dependent rats." | 4.12 | Persistent effects of the orexin-1 receptor antagonist SB-334867 on naloxone precipitated morphine withdrawal symptoms and nociceptive behaviors in morphine dependent rats. ( Gholami, M; Joghataei, MT; Komaki, A; Kourosh-Arami, M; Lavaie, M; Najafi, Z, 2022) |
| "Orexin neuropeptides are implicated in the expression of morphine dependence." | 4.02 | Central blockade of orexin type 1 receptors reduces naloxone induced activation of locus coeruleus neurons in morphine dependent rats. ( Aghajani, N; Azizi, H; Pourhamzeh, M; Semnanian, S, 2021) |
| " We tested SB 334867 in three doses (10, 20 and 30 mg/kg), TCS-OX2-29 in two doses (5 and 10 mg/kg) and morphine with highest effective dose based on our dose-response experiment (5 mg/kg)." | 1.39 | The differential effects of OX1R and OX2R selective antagonists on morphine conditioned place preference in naïve versus morphine-dependent mice. ( Dehpour, AR; Esmaeili, B; Ghaffarpour, M; Javadi-Paydar, M; Mirbaha, H; Motiei-Langroudi, R; Tabaeizadeh, M; Tahsili-Fahadan, P, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (18.18) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (54.55) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Kourosh-Arami, M | 1 |
| Joghataei, MT | 1 |
| Komaki, A | 1 |
| Gholami, M | 1 |
| Najafi, Z | 1 |
| Lavaie, M | 1 |
| Aghajani, N | 1 |
| Pourhamzeh, M | 1 |
| Azizi, H | 3 |
| Semnanian, S | 3 |
| Jamali, S | 1 |
| Zarrabian, S | 3 |
| Haghparast, A | 4 |
| Sahafzadeh, M | 1 |
| Karimi-Haghighi, S | 1 |
| Mousavi, Z | 2 |
| Edalat, P | 1 |
| Kavianpour, M | 1 |
| Assar, N | 1 |
| Mahmoudi, D | 1 |
| Mousavi, Y | 1 |
| Mirnajafi-Zadeh, J | 2 |
| Javan, M | 1 |
| Rohampour, K | 1 |
| Tabaeizadeh, M | 1 |
| Motiei-Langroudi, R | 1 |
| Mirbaha, H | 1 |
| Esmaeili, B | 1 |
| Tahsili-Fahadan, P | 1 |
| Javadi-Paydar, M | 1 |
| Ghaffarpour, M | 1 |
| Dehpour, AR | 1 |
| SEAGER, CP | 1 |
| FOSTER, AR | 1 |
| HAMBURGER, E | 1 |
11 other studies available for urea and Morphine Abuse
| Article | Year |
|---|---|
Persistent effects of the orexin-1 receptor antagonist SB-334867 on naloxone precipitated morphine withdrawal symptoms and nociceptive behaviors in morphine dependent rats.
Topics: Animals; Behavior, Animal; Benzoxazoles; Disease Models, Animal; Morphine; Morphine Dependence; Nalo | 2022 |
Central blockade of orexin type 1 receptors reduces naloxone induced activation of locus coeruleus neurons in morphine dependent rats.
Topics: Action Potentials; Analgesics, Opioid; Animals; Benzoxazoles; Injections, Intraperitoneal; Injection | 2021 |
Similar role of mPFC orexin-1 receptors in the acquisition and expression of morphine- and food-induced conditioned place preference in male rats.
Topics: Animals; Benzoxazoles; Conditioning, Operant; Drug-Seeking Behavior; Food; Male; Morphine; Morphine | 2021 |
Role of the orexin receptors within the nucleus accumbens in the drug priming-induced reinstatement of morphine seeking in the food deprived rats.
Topics: Animals; Benzoxazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Drug-Seeking Behavi | 2018 |
Role of orexin-1 and orexin-2 receptors in the CA1 region of hippocampus in the forced swim stress- and food deprivation-induced reinstatement of morphine seeking behaviors in rats.
Topics: Animals; Benzoxazoles; CA1 Region, Hippocampal; Drug-Seeking Behavior; Extinction, Psychological; Fo | 2018 |
Role of orexin-1 and -2 receptors within the nucleus accumbens in the acquisition of sensitization to morphine in rats.
Topics: Animals; Benzoxazoles; Conditioning, Classical; Conditioning, Operant; Conditioning, Psychological; | 2019 |
Blockade of orexin type-1 receptors in locus coeruleus nucleus attenuates the development of morphine dependency in rats.
Topics: Animals; Benzoxazoles; Locus Coeruleus; Male; Morphine; Morphine Dependence; Naphthyridines; Orexin | 2014 |
Antagonism of orexin type 1 receptors in the locus coeruleus attenuates signs of naloxone-precipitated morphine withdrawal in rats.
Topics: Animals; Benzoxazoles; Injections, Intraventricular; Locus Coeruleus; Male; Morphine; Morphine Depen | 2010 |
The differential effects of OX1R and OX2R selective antagonists on morphine conditioned place preference in naïve versus morphine-dependent mice.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Antigens, Surface; Benzoxazoles; Conditioning, Op | 2013 |
Addiction to unrestricted drugs.
Topics: Behavior, Addictive; Bromides; Chloroform; Medical Records; Morphine Dependence; Morphine Derivative | 1958 |
BARBITURATE USE IN NARCOTIC ADDICTS.
Topics: Barbiturates; Codeine; Drug Tolerance; Ethchlorvynol; Glutethimide; Heroin; Hydromorphone; Hypnotics | 1964 |