urea has been researched along with Medulloblastoma in 10 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Medulloblastoma: A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dasatinib treatment caused tumor regression in vivo." | 5.40 | Dasatinib suppression of medulloblastoma survival and migration is markedly enhanced by combining treatment with the aurora kinase inhibitor AT9283. ( Cho, YJ; Liu, J; MacDonald, TJ; Petersen, W; Schneiderjan, M; Yuan, L; Zhang, H, 2014) |
| "Dasatinib treatment caused tumor regression in vivo." | 1.40 | Dasatinib suppression of medulloblastoma survival and migration is markedly enhanced by combining treatment with the aurora kinase inhibitor AT9283. ( Cho, YJ; Liu, J; MacDonald, TJ; Petersen, W; Schneiderjan, M; Yuan, L; Zhang, H, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lawson, C | 1 |
| Ahmed Alta, TB | 1 |
| Moschou, G | 1 |
| Skamnaki, V | 1 |
| Solovou, TGA | 1 |
| Topham, C | 1 |
| Hayes, J | 1 |
| Snape, TJ | 1 |
| Krüger, K | 1 |
| Geist, K | 1 |
| Stuhldreier, F | 1 |
| Schumacher, L | 1 |
| Blümel, L | 1 |
| Remke, M | 2 |
| Wesselborg, S | 1 |
| Stork, B | 1 |
| Klöcker, N | 1 |
| Bormann, S | 1 |
| Roos, WP | 1 |
| Honnen, S | 1 |
| Fritz, G | 1 |
| Petersen, W | 1 |
| Liu, J | 1 |
| Yuan, L | 1 |
| Zhang, H | 1 |
| Schneiderjan, M | 1 |
| Cho, YJ | 1 |
| MacDonald, TJ | 1 |
| Prince, EW | 1 |
| Balakrishnan, I | 1 |
| Shah, M | 1 |
| Mulcahy Levy, JM | 1 |
| Griesinger, AM | 1 |
| Alimova, I | 1 |
| Harris, PS | 1 |
| Birks, DK | 1 |
| Donson, AM | 1 |
| Davidson, N | 1 |
| Taylor, MD | 1 |
| Handler, MH | 1 |
| Foreman, NK | 1 |
| Venkataraman, S | 1 |
| Vibhakar, R | 1 |
| URCIUOLI, R | 1 |
| SATO, R | 1 |
| Egami, H | 1 |
| Takeshita, I | 1 |
| Fukui, M | 1 |
| Kitamura, K | 1 |
| Wilson, CB | 1 |
| Boldrey, EB | 1 |
| Enot, KJ | 1 |
| Walker, MD | 1 |
| Hurwitz, BS | 1 |
2 trials available for urea and Medulloblastoma
| Article | Year |
|---|---|
1,3-bis (2-chloroethyl)-1-nitrosourea (NSC-409962) in the treatment of brain tumors.
Topics: Adenocarcinoma; Adolescent; Antineoplastic Agents; Astrocytoma; Brain Neoplasms; Chordoma; Clinical | 1970 |
BCNU (1,3-bis(2-chloroethyl)-1-nitrosourea; NSC-409962) in the treatment of malignant brain tumor--a preliminary report.
Topics: Adolescent; Adult; Aged; Alanine Transaminase; Alopecia; Antineoplastic Agents; Aspartate Aminotrans | 1970 |
8 other studies available for urea and Medulloblastoma
| Article | Year |
|---|---|
Novel diarylamides and diarylureas with N-substitution dependent activity against medulloblastoma.
Topics: Amides; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cerebellar Neoplasms; Dose-Resp | 2021 |
Multiple DNA damage-dependent and DNA damage-independent stress responses define the outcome of ATR/Chk1 targeting in medulloblastoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ataxia Telangiectasia Mutated Proteins; Cae | 2018 |
Dasatinib suppression of medulloblastoma survival and migration is markedly enhanced by combining treatment with the aurora kinase inhibitor AT9283.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Aut | 2014 |
Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzodiazepinones; Biomarkers, Tumor; Cel | 2016 |
[A NEW OSMOTIC DRUG: HYPERTONIC SOLUTION OF MANNITOL. ADVANTAGES AS COMPARED WITH UREA. USE IN THE TREATMENT OF ASEPTIC SEROUS MENINGITIS AND POSTOPERATIVE CEREBROSPINAL FLUID FISTULAS].
Topics: Brain Neoplasms; Cerebellar Neoplasms; Cochlear Nerve; Ependymoma; Fistula; Glioma; Hypertonic Solut | 1963 |
[CLINICAL STUDIES ON INTRACRANIAL PRESSURE-LOWERING AGENTS WITH SPECIAL REFERENCE TO HYPERTONIC UREA SOLUTION. 2].
Topics: Adolescent; Brain Edema; Brain Neoplasms; Cerebellar Neoplasms; Child; Craniocerebral Trauma; Cranio | 1964 |
Supernumerary lactate dehydrogenase isozymes in human gliomas.
Topics: Astrocytoma; Brain Neoplasms; Chemical Phenomena; Chemistry; Ependymoma; Glioma; Hot Temperature; Hu | 1983 |
Medulloblastoma.
Topics: Adolescent; Age Factors; Brain Neoplasms; Child; Child, Preschool; Female; Gold Isotopes; Humans; In | 1971 |