urea has been researched along with Malaria in 24 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A series of amide (8–32, 40–45) and urea (33, 34, 36–39) analogues based on the thiaplakortone A natural product scaffold were synthesised and screened for in vitro antimalarial activity against chloroquine-sensitive (3D7) and chloroquine- and mefloquine-resistant (Dd2) Plasmodium falciparum parasite lines." | 7.81 | Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold. ( Andrews, KT; Beattie, KD; Blundell, S; Campbell, A; Charman, SA; Coster, MJ; Davis, RA; Edstein, MD; Healy, PC; Koltun, M; MacKenzie, D; Pouwer, RH; Quinn, RJ; Schwartz, BD; Skinner-Adams, TS, 2015) |
| " To investigate the cattle urine, and its main nitrogenous compound, urea, as a potential supplementary diet for malaria vectors, feeding parameters and life history traits were measured." | 4.12 | Malaria mosquitoes acquire and allocate cattle urine to enhance life history traits. ( Birgersson, G; Dawit, M; Hill, SR; Ignell, R; Tekie, H, 2022) |
| "A series of amide (8–32, 40–45) and urea (33, 34, 36–39) analogues based on the thiaplakortone A natural product scaffold were synthesised and screened for in vitro antimalarial activity against chloroquine-sensitive (3D7) and chloroquine- and mefloquine-resistant (Dd2) Plasmodium falciparum parasite lines." | 3.81 | Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold. ( Andrews, KT; Beattie, KD; Blundell, S; Campbell, A; Charman, SA; Coster, MJ; Davis, RA; Edstein, MD; Healy, PC; Koltun, M; MacKenzie, D; Pouwer, RH; Quinn, RJ; Schwartz, BD; Skinner-Adams, TS, 2015) |
| "We evaluated plasma creatinine, urea, bilirubin, lactic acid, and nitric oxide values in children with malaria to identify indices of disease severity and predictors of fatal outcomes." | 3.75 | Physiopathologic factors resulting in poor outcome in childhood severe malaria in Cameroon. ( Amvam Z, PH; Combes, V; Fotso K, H; Gouado, I; Grau, GE; Nguélé, S; Pankoui M, JB; Zambou, O, 2009) |
| "The urea level was found elevated in liver, brain and plasma during P." | 1.30 | Status of urea and related enzymes during Plasmodium yoelii infection and pyrimethamine treatment in mice. ( Agrawal, A; Pandey, VC; Tripathi, LM, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (58.33) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 3 (12.50) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Dawit, M | 1 |
| Hill, SR | 1 |
| Birgersson, G | 1 |
| Tekie, H | 1 |
| Ignell, R | 1 |
| Roy, S | 1 |
| Perez-Guaita, D | 1 |
| Andrew, DW | 1 |
| Richards, JS | 1 |
| McNaughton, D | 1 |
| Heraud, P | 1 |
| Wood, BR | 1 |
| Calice-Silva, V | 1 |
| Sacomboio, E | 1 |
| Raimann, JG | 1 |
| Evans, R | 1 |
| Dos Santos Sebastião, C | 1 |
| Tchivango, AT | 1 |
| Kotanko, P | 1 |
| Levin, N | 1 |
| Pecoits-Filho, R | 1 |
| Schwartz, BD | 1 |
| Skinner-Adams, TS | 1 |
| Andrews, KT | 1 |
| Coster, MJ | 1 |
| Edstein, MD | 1 |
| MacKenzie, D | 1 |
| Charman, SA | 2 |
| Koltun, M | 1 |
| Blundell, S | 1 |
| Campbell, A | 1 |
| Pouwer, RH | 1 |
| Quinn, RJ | 1 |
| Beattie, KD | 1 |
| Healy, PC | 1 |
| Davis, RA | 1 |
| Gouado, I | 1 |
| Pankoui M, JB | 1 |
| Fotso K, H | 1 |
| Zambou, O | 1 |
| Nguélé, S | 1 |
| Combes, V | 1 |
| Grau, GE | 1 |
| Amvam Z, PH | 1 |
| Mesia, GK | 1 |
| Tona, GL | 1 |
| Penge, O | 1 |
| Lusakibanza, M | 1 |
| Nanga, TM | 1 |
| Cimanga, RK | 1 |
| Apers, S | 1 |
| Van Miert, S | 1 |
| Totte, J | 1 |
| Pieters, L | 1 |
| Vlietinck, AJ | 1 |
| Padmanilayam, M | 1 |
| Scorneaux, B | 1 |
| Dong, Y | 1 |
| Chollet, J | 1 |
| Matile, H | 1 |
| Creek, DJ | 1 |
| Charman, WN | 1 |
| Tomas, JS | 1 |
| Scheurer, C | 1 |
| Wittlin, S | 1 |
| Brun, R | 1 |
| Vennerstrom, JL | 1 |
| Urbański, T | 1 |
| Serafin, B | 1 |
| Zylowski, J | 1 |
| Agrawal, A | 1 |
| Tripathi, LM | 1 |
| Pandey, VC | 1 |
| Kan, SC | 1 |
| Siddiqui, WA | 1 |
| Lal, DM | 1 |
| Hussain, QZ | 1 |
| Smitskampen, H | 1 |
| Wolthuis, FH | 2 |
| Schmitz, B | 1 |
| Gelfand, M | 1 |
| Peters, W | 1 |
| Davies, EE | 1 |
| Robinson, BL | 1 |
| Haines, H | 1 |
| Farmer, JN | 1 |
| Zanner, MA | 1 |
| Galey, WR | 1 |
| Scaletti, JV | 1 |
| Brahm, J | 1 |
| Vander Jagt, DL | 1 |
| Donadio, JV | 1 |
| Whelton, A | 1 |
| Kazyak, L | 1 |
| Wilson, RJ | 1 |
| McGregor, IA | 1 |
| Cranfield, R | 1 |
| Goodford, PJ | 1 |
| Norrington, FE | 1 |
| Richards, WH | 1 |
| Sheppey, GC | 1 |
| Williams, SG | 1 |
| Canfield, CJ | 1 |
| Miller, LH | 1 |
| Bartelloni, PJ | 1 |
| Eichler, P | 1 |
| Barry, KG | 1 |
| Mukherjee, AP | 1 |
| White, JC | 1 |
| Lau, KS | 1 |
| Briggs, M | 1 |
| Briggs, MH | 1 |
| Kingston, ME | 1 |
| Smitskamp, H | 1 |
24 other studies available for urea and Malaria
| Article | Year |
|---|---|
Malaria mosquitoes acquire and allocate cattle urine to enhance life history traits.
Topics: Animals; Anopheles; Cattle; Feeding Behavior; Female; Life History Traits; Malaria; Mosquito Vectors | 2022 |
Simultaneous ATR-FTIR Based Determination of Malaria Parasitemia, Glucose and Urea in Whole Blood Dried onto a Glass Slide.
Topics: Area Under Curve; Discriminant Analysis; Dried Blood Spot Testing; Glass; Glucose; Humans; Least-Squ | 2017 |
Diagnostic performance of salivary urea nitrogen dipstick to detect and monitor acute kidney disease in patients with malaria.
Topics: Acute Kidney Injury; Adolescent; Adult; Angola; Biomarkers; Child; Diagnostic Tests, Routine; Female | 2018 |
Synthesis and antimalarial evaluation of amide and urea derivatives based on the thiaplakortone A natural product scaffold.
Topics: Amides; Animals; Antimalarials; Atovaquone; Biological Products; Cell Line; Chemistry Techniques, Sy | 2015 |
Physiopathologic factors resulting in poor outcome in childhood severe malaria in Cameroon.
Topics: Bilirubin; Biomarkers; Cameroon; Child; Child, Preschool; Creatinine; Female; Humans; Infant; Infant | 2009 |
Antimalarial activities and toxicities of three plants used as traditional remedies for malaria in the Democratic Republic of Congo: Croton mubango , Nauclea pobeguinii and Pyrenacantha staudtii.
Topics: Animals; Antimalarials; Aspartate Aminotransferases; Creatinine; Croton; Female; Malaria; Male; Mice | 2005 |
Antimalarial activity of N-alkyl amine, carboxamide, sulfonamide, and urea derivatives of a dispiro-1,2,4-trioxolane piperidine.
Topics: Amines; Animals; Antimalarials; Humans; Malaria; Mice; Microsomes, Liver; Piperidines; Plasmodium be | 2006 |
Potential antimalarial compounds. IX. Pyrimidine derivatives of urea and guanidine.
Topics: Animals; Antimalarials; Chemistry, Organic; Chloroquine; Guanidines; Malaria; Mice; Organic Chemistr | 1967 |
Status of urea and related enzymes during Plasmodium yoelii infection and pyrimethamine treatment in mice.
Topics: Animals; Antimalarials; Liver; Malaria; Mice; Plasmodium yoelii; Pyrimethamine; Urea | 1997 |
Comparative studies on dihydrofolate reductases from Plasmodium falciparum and Aotus trivirgatus.
Topics: Animals; Aotus trivirgatus; Erythrocytes; Haplorhini; Hydrogen-Ion Concentration; Malaria; Molecular | 1979 |
Urea and electrolyte studies in albino rats in Plasmodium berghei infection.
Topics: Animals; Chlorides; Malaria; Male; Plasmodium berghei; Potassium; Rats; Sodium; Urea | 1979 |
[The treatment of severe tropical malaria].
Topics: Adrenal Cortex Hormones; Antimalarials; Dextrans; Edema; Heparin; Humans; Malaria; Microcirculation; | 1976 |
A study of the clinical features of malaria in Rhodesia.
Topics: Adult; Female; Humans; Immunoglobulins; Malaria; Male; Proteinuria; Sickle Cell Trait; Urea; Zimbabw | 1976 |
The chemotherapy of rodent malaria, XXIII Causal prophylaxis, part II: Practical experience with Plasmodium yoelii nigeriensis in drug screening.
Topics: Amidines; Aminoquinolines; Animals; Anti-Bacterial Agents; Antimalarials; Drug Evaluation, Preclinic | 1975 |
Glomerular filtration rate and plasma solutes in BALB/c mice infected with Plasmodium berghei.
Topics: Analysis of Variance; Animals; Chlorides; Glomerular Filtration Rate; Glomerulonephritis; Immune Com | 1991 |
Water and urea transport in human erythrocytes infected with the malaria parasite Plasmodium falciparum.
Topics: Animals; Cell Membrane Permeability; Erythrocyte Membrane; Humans; Malaria; Microscopy, Electron, Sc | 1990 |
Quinine therapy and peritoneal dialysis in acute renal failure complicating malarial haemoglobinuria.
Topics: Acute Kidney Injury; Adult; Creatinine; Drug Resistance, Microbial; Hemoglobinuria; Humans; Infusion | 1968 |
Immunoglobulin characteristics of antibodies to malarial S-antigens in man.
Topics: Animals; Antibodies; Antigen-Antibody Complex; Antigen-Antibody Reactions; Female; Goats; Humans; Im | 1973 |
The selection of arylamidinourea antimalarials by their predicted physicochemical properties.
Topics: Amidines; Animals; Antimalarials; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Macac | 1974 |
Acute renal failure in Plasmodium falciparum malaria. Treatment of peritoneal dialysis.
Topics: Acute Kidney Injury; Adult; Creatinine; Electrocardiography; Humans; Kinetics; Malaria; Male; Milita | 1968 |
Falciparum malaria associated with jaundice, renal failure and anaemia.
Topics: Acute Kidney Injury; Adult; Anemia; Antimalarials; Bilirubin; Biopsy; Humans; Jaundice; Kidney; Live | 1971 |
Effects of some tropical diseases on the urea index.
Topics: Ancylostomiasis; Creatinine; Female; Humans; Kidney; Malaria; Male; Schistosomiasis; Tropical Medici | 1972 |
Experience with urea in invert sugar for the treatment of cerebral malaria.
Topics: Brain Diseases; Child, Preschool; Coma; Encephalitis; Fructose; Glucose; Hemoglobinuria; Humans; Inf | 1971 |
New concepts in treatment of malignant tertian malaria with cerebral involvement.
Topics: Adult; Brain Diseases; Brain Edema; Dexamethasone; Dextrans; Drug Synergism; Heparin; Humans; Malari | 1971 |