urea has been researched along with Malaria, Falciparum in 9 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Malaria, Falciparum: Malaria caused by PLASMODIUM FALCIPARUM. This is the severest form of malaria and is associated with the highest levels of parasites in the blood. This disease is characterized by irregularly recurring febrile paroxysms that in extreme cases occur with acute cerebral, renal, or gastrointestinal manifestations.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To establish the effects of chloroquine on kidney function we monitored renal parameters in age and sex matched control subjects and patients who presented with acute transient fever." | 7.70 | Chloroquine influences renal function in rural Zimbabweans with acute transient fever. ( Munjeri, O; Musabayane, CT; Musvibe, A; Osim, EE; Wenyika, J, 1999) |
| "Severe Plasmodium falciparum malaria is associated with hypoargininemia, which contributes to impaired systemic and pulmonary nitric oxide (NO) production and endothelial dysfunction." | 3.76 | Dysregulation of L-arginine metabolism and bioavailability associated to free plasma heme. ( Cortelezzi, L; Dondorp, AM; Omodeo-Salè, F; Scaccabarozzi, D; Vommaro, Z, 2010) |
| " The factors are more common in cases with high mortality with diastolic blood pressure (DBP) below 60 mm of Hg, anaemia, persistence of Glasgow Coma Score below 5 on day 2, high parasite count at presentation, proteinuria and high level of serum urea." | 3.70 | Cerebral malaria--a study of 104 cases. ( Faiz, MA; Hossain, MA; Rahman, MR; Rashid, HA, 1998) |
| "To establish the effects of chloroquine on kidney function we monitored renal parameters in age and sex matched control subjects and patients who presented with acute transient fever." | 3.70 | Chloroquine influences renal function in rural Zimbabweans with acute transient fever. ( Munjeri, O; Musabayane, CT; Musvibe, A; Osim, EE; Wenyika, J, 1999) |
| "We studied 38 patients with acute renal failure (ARF) due to malaria over a 5-year period between 1990 and 1994 at the Institute of Urology and Transplantation." | 1.29 | Predictors of outcome in malarial renal failure. ( Abbas, K; Ahmad, E; Akhtar, F; Naqvi, A; Naqvi, R; Rizvi, A; Yazdani, I, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singh, P | 2 |
| Raj, R | 1 |
| Gut, J | 1 |
| Rosenthal, PJ | 1 |
| Kumar, V | 1 |
| Verlinden, BK | 1 |
| de Beer, M | 1 |
| Pachaiyappan, B | 1 |
| Besaans, E | 1 |
| Andayi, WA | 1 |
| Reader, J | 1 |
| Niemand, J | 1 |
| van Biljon, R | 1 |
| Guy, K | 1 |
| Egan, T | 1 |
| Woster, PM | 1 |
| Birkholtz, LM | 1 |
| Mishra, P | 1 |
| Hosur, RV | 1 |
| Omodeo-Salè, F | 1 |
| Cortelezzi, L | 1 |
| Vommaro, Z | 1 |
| Scaccabarozzi, D | 1 |
| Dondorp, AM | 1 |
| Kortagere, S | 1 |
| Welsh, WJ | 1 |
| Morrisey, JM | 1 |
| Daly, T | 1 |
| Ejigiri, I | 1 |
| Sinnis, P | 1 |
| Vaidya, AB | 1 |
| Bergman, LW | 1 |
| Anderson, JW | 1 |
| Sarantakis, D | 1 |
| Terpinski, J | 1 |
| Kumar, TR | 1 |
| Tsai, HC | 1 |
| Kuo, M | 1 |
| Ager, AL | 1 |
| Jacobs, WR | 1 |
| Schiehser, GA | 1 |
| Ekins, S | 1 |
| Sacchettini, JC | 1 |
| Jacobus, DP | 1 |
| Fidock, DA | 1 |
| Freundlich, JS | 1 |
| Naqvi, R | 1 |
| Ahmad, E | 1 |
| Akhtar, F | 1 |
| Yazdani, I | 1 |
| Abbas, K | 1 |
| Naqvi, A | 1 |
| Rizvi, A | 1 |
| Faiz, MA | 1 |
| Rahman, MR | 1 |
| Hossain, MA | 1 |
| Rashid, HA | 1 |
| Musabayane, CT | 1 |
| Musvibe, A | 1 |
| Wenyika, J | 1 |
| Munjeri, O | 1 |
| Osim, EE | 1 |
9 other studies available for urea and Malaria, Falciparum
| Article | Year |
|---|---|
Urea/oxalamide tethered β-lactam-7-chloroquinoline conjugates: synthesis and in vitro antimalarial evaluation.
Topics: Antimalarials; beta-Lactams; Chloroquine; Humans; Malaria, Falciparum; Oxamic Acid; Plasmodium falci | 2014 |
Interrogating alkyl and arylalkylpolyamino (bis)urea and (bis)thiourea isosteres as potent antimalarial chemotypes against multiple lifecycle forms of Plasmodium falciparum parasites.
Topics: Alkylation; Antimalarials; Humans; Life Cycle Stages; Malaria, Falciparum; Plasmodium falciparum; Po | 2015 |
Urea Dependent (15)N NMR-Relaxation Studies on PfP2 Multimers Reveal that the C-Terminal Behaves like an Independent Intrinsically Disordered Peptide.
Topics: Amino Acid Sequence; Humans; Intrinsically Disordered Proteins; Malaria, Falciparum; Molecular Seque | 2015 |
Dysregulation of L-arginine metabolism and bioavailability associated to free plasma heme.
Topics: Amino Acid Transport System y+; Amino Acid Transport System y+L; Arginase; Arginine; Biological Avai | 2010 |
Structure-based design of novel small-molecule inhibitors of Plasmodium falciparum.
Topics: Antimalarials; Crystallography, X-Ray; Drug Design; Humans; Malaria, Falciparum; Models, Molecular; | 2010 |
Novel diaryl ureas with efficacy in a mouse model of malaria.
Topics: Animals; Antimalarials; Benzene Derivatives; Disease Models, Animal; Drug Discovery; Malaria, Falcip | 2013 |
Predictors of outcome in malarial renal failure.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Animals; Antimalarials; Creatinine; Female; Hematuria; | 1996 |
Cerebral malaria--a study of 104 cases.
Topics: Adult; Anemia; Animals; Cause of Death; Coma; Endemic Diseases; Female; Fever; Glasgow Coma Scale; H | 1998 |
Chloroquine influences renal function in rural Zimbabweans with acute transient fever.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antimalarials; Blood Pressure; Chloroquin | 1999 |