Page last updated: 2024-10-21

urea and Leukemia L 1210

urea has been researched along with Leukemia L 1210 in 51 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199047 (92.16)18.7374
1990's3 (5.88)18.2507
2000's0 (0.00)29.6817
2010's1 (1.96)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ren, F1
Zhong, Y1
Mai, X1
Liao, YJ1
Liu, C1
Feng, LH1
Sun, W1
Zen, WB1
Liu, WM1
Liu, J1
Jin, N1
SCHABEL, FM2
JOHNSTON, TP4
McCALEB, GS3
MONTGOMERY, JA3
LASTER, WR1
SKIPPER, HE2
SCHRECKER, AW1
HUENNEKENS, FM3
STEARNS, B1
LOSEE, KA1
BERNSTEIN, J1
ADAMSON, RH3
Tyrer, DD3
Kline, I3
Venditti, JM3
Goldin, A6
Nelson, HG1
Shelton, FJ1
Wetzel, WH1
Wilkoff, LJ1
Dixon, GJ1
Dulmadge, EA1
Cates, LA1
Cress, AE1
Bowden, GT1
Konstantinov, S1
Topashka-Ancheva, M1
Karaivanova, M1
Zoneva, G1
Galova, I1
Walker, DL1
Reid, JM1
Ames, MM1
Fukutomi, R1
Kagechika, H1
Hashimoto, Y1
Shudo, K1
Fuji, H1
Mihich, E6
Duffy, TH1
Beckman, SB1
Peterson, SM1
Vitols, KS1
Schein, PS1
Gorbacheva, LB2
Kukushkina, GV2
McCullough, JL1
Bertino, JR1
Denny, GH1
Ryder, MA1
Gang, M1
Artis, EW1
Dave, C3
Ashton, WT1
Kirk, LL1
Baker, BR1
Ehrke, J1
Korytnyk, W1
Ghosh, AC1
Angelino, N1
Ringertz, NR1
Bolund, L1
Oliverio, VT2
Vietzke, WM1
Williams, MK1
Cheng, CJ1
Fujimura, S1
Grunberger, D1
Weinstein, IB1
Cohen, MH2
Carbone, PP1
Groth, DP1
D'Angelo, JM1
Vogler, WR1
Mingioli, ES1
Betz, B1
Bray, DA1
DeVita, VT2
Kitano, M1
Reyes, P1
Bonmassar, E1
Bonmassar, A1
Vadlamudi, S2
Sokolova, IS1
Mizuno, NS1
Humphrey, EW1
Young, RC1
Shirakawa, S1
Frei, E1
Soucek, J1
Ehrke, MJ1
Wheeler, GP3
Bowdon, BJ3
Adamson, DJ1
Vail, MH1
Mulhern, AI1
Waravdekar, VS1
Choudry, JN1
Lerner, LJ1
Bianchi, A1
Yiacas, E1
Borman, A1
Opliger, PS1

Reviews

1 review available for urea and Leukemia L 1210

ArticleYear
Factors pertaining to complete drug-induced remission of tumor in animals and man.
    Cancer research, 1969, Volume: 29, Issue:12

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Humans; Leukemia L1210; Methotrexate;

1969

Other Studies

50 other studies available for urea and Leukemia L 1210

ArticleYear
Synthesis and anticancer evaluation of benzyloxyurea derivatives.
    Chemical & pharmaceutical bulletin, 2014, Volume: 62, Issue:9

    Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; K562 Cells; Leukemia L1210

2014
Experimental evaluation of potential anticancer agents VIII. Effects of certain nitrosoureas on intracerebral L1210 leukemia.
    Cancer research, 1963, Volume: 23

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Brain Neoplasms; Leukemia L1210; Nitroso Compound

1963
FURTHER OBSERVATIONS OF THE BINDING AND INHIBITION OF DIHYDROFOLIC REDUCTASE BY FOLIC ACID ANTAGONISTS.
    Biochemical pharmacology, 1964, Volume: 13

    Topics: Aminopterin; Animals; Chromatography; Dialysis; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonist

1964
THE SYNTHESIS OF ANTINEOPLASTIC AGENTS. XXXII. N-NITROSOUREAS. I.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Leukemia L1210; Mice; Nitroso Compounds;

1963
HYDROXYUREA. A NEW TYPE OF POTENTIAL ANTITUMOR AGENT.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Animals; Antineoplastic Agents; Hydroxyurea; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice;

1963
ACTIVITY OF CONGENERS OF HYDROXYUREA AGAINST ADVANCED LEUKEMIA L1210.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119

    Topics: Animals; Guanidine; Guanidines; Hydrazines; Hydroxylamines; Hydroxyurea; Leukemia L1210; Mice; Pharm

1965
Separate and sequential chemotherapy of mouse leukemia L1210 with 1-beta-D-arabinofuranosylcytosine hydrochloride and 1,3-bis(2-chloroethyl)-1-nitrosourea.
    Cancer research, 1967, Volume: 27, Issue:5

    Topics: Animals; Cytarabine; Injections; Leukemia L1210; Longevity; Mice; Nitroso Compounds; Urea

1967
Potential carcinostatic agents. I. Derivatives and analogs of 1-(2-hydroxyethyl)-3-(4-tolyl)urea.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:4

    Topics: Animals; Carcinoma; Chemistry, Organic; Leukemia L1210; Lung Neoplasms; Mice; Neoplasms, Experimenta

1967
Effect of 1,3-bis(2-chlorethyl)-1-nitrosourea (NSC-409962) and nitrogen mustard (NSC-762) on kinetic behavior of cultured L1210 leukemic cells.
    Cancer chemotherapy reports, 1967, Volume: 51, Issue:1

    Topics: Alkylating Agents; Animals; Biological Assay; Culture Techniques; Kinetics; Leukemia L1210; Mechlore

1967
Phosphorus-nitrogen compounds. VII. Urea, aziridinecarboxamide, and semicarbazide derivatives.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:5

    Topics: Amides; Animals; Antimalarials; Antineoplastic Agents; Azirines; Carcinoma 256, Walker; Leukemia L12

1967
Criteria associated with destruction of leukemia and solid tumor cells in animals.
    Cancer research, 1967, Volume: 27, Issue:12

    Topics: Animals; Cricetinae; Cyclophosphamide; Cytarabine; Leukemia L1210; Methotrexate; Mice; Neoplasm Tran

1967
Covalent DNA-protein crosslinking occurs after hyperthermia and radiation.
    Radiation research, 1983, Volume: 95, Issue:3

    Topics: Animals; Cell Line; DNA; Dose-Response Relationship, Radiation; Guanidine; Guanidines; Hot Temperatu

1983
Antitumor, nephrotoxic and clastogenic effect of cis-DDP with DDTC or NAC.
    Neoplasma, 1994, Volume: 41, Issue:5

    Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Creatinine; Diti

1994
Preclinical pharmacology of bizelesin, a potent bifunctional analog of the DNA-binding antibiotic CC-1065.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:4

    Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Chromat

1994
Novel aromatic urea derivatives with DNA-binding ability.
    Chemical & pharmaceutical bulletin, 1996, Volume: 44, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Cattle; Cell Division; DNA; Humans; KB Cells; Kinetics; Leukemia L12

1996
Selection for high immunogenicity in drug-resistant sublines of murine lymphomas demonstrated by plaque assay.
    Cancer research, 1975, Volume: 35, Issue:4

    Topics: Animals; Antibodies, Neoplasm; Antibody-Producing Cells; Antigens, Neoplasm; Antineoplastic Agents;

1975
L1210 dihydrofolate reductase. Kinetics and mechanism of activation by various agents.
    The Journal of biological chemistry, 1987, May-25, Volume: 262, Issue:15

    Topics: Animals; Cell Line; Chloromercuribenzoates; Dithionitrobenzoic Acid; Enzyme Activation; Guanidine; G

1987
1-methyl-1-nitrosourea and dialkylnitrosamine depression of nicotinamide adenine dinucleotide.
    Cancer research, 1969, Volume: 29, Issue:6

    Topics: Animals; Depression, Chemical; Leukemia L1210; Liver; Male; N-Glycosyl Hydrolases; NAD; Niacinamide;

1969
Some aspects of the mechanism of action of 1-propyl-1-nitrosourea.
    Biochemical pharmacology, 1970, Volume: 19, Issue:5

    Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular

1970
Dihydrofolate reductase from mouse liver and spleen. Purification, properties and inhibition by substituted 2,4-diaminopyrimidines and 4,6-diaminotriazines.
    Biochemical pharmacology, 1971, Volume: 20, Issue:3

    Topics: Animals; Antigen-Antibody Reactions; Cell Line; Chromatography; Chromatography, Gel; Enzyme Activati

1971
Alpha-(Ureidomethylene)lactones and derived 5-(hydroxyalkyl)uracils.
    Journal of medicinal chemistry, 1974, Volume: 17, Issue:11

    Topics: Animals; Lactones; Leukemia L1210; Spectrophotometry, Ultraviolet; Uracil; Urea

1974
Evaluation of antileukemic agents in advanced leukemia L1210 in mice. X.
    Cancer chemotherapy reports. Part 2, 1972, Volume: 3, Issue:1

    Topics: Alkylating Agents; Amides; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine;

1972
Uptake and intracellular distribution of 4,4'-diacetyldiphenylurea-bis-(Guanylhydrazone) in sensitive and resistant leukemia L1210 cells.
    Biochemical pharmacology, 1972, Oct-15, Volume: 21, Issue:20

    Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cell Line; Cell Membrane; Cell Nucleus; Centrifugat

1972
Irreversible enzyme inhibitors. 198. Diaminodihydro-S-triazines and diaminopyrimidines bearing substituted (ureidomethyl)phenyl substituents as reversible inhibitors of dihydrofolate reductase.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:5

    Topics: Animals; Carbamates; Cell Survival; Cells, Cultured; Folic Acid Antagonists; Leukemia L1210; Methods

1973
Mechanism of the inhibition of DNA biosynthesis by 4,4'-diacetyldiphenylurea-bis(guanylhydrazone) in leukemia L1210 cells.
    Cancer research, 1973, Volume: 33, Issue:9

    Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cell-Free System; Cells, Cultured; DNA Nucleotidylt

1973
Guanylhydrazones with potential antileukemic activity. 1. Aza analogs of 4,4'-diacetyldiphenylurea bis(guanylhydrazone).
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Aza Compounds; DNA Nucleotidyltransferases; DNA, Neo

1973
Actinomycin binding capacity of deoxyribonucleoprotein.
    Biochimica et biophysica acta, 1969, Jan-21, Volume: 174, Issue:1

    Topics: Animals; Animals, Newborn; Binding Sites; Calcium; Cattle; Chemical Phenomena; Chemistry; Chickens;

1969
The absorption, distribution, excretion, and biotransformation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in animals.
    Cancer research, 1970, Volume: 30, Issue:5

    Topics: Animals; Antineoplastic Agents; Biotransformation; Carbon Isotopes; Chromatography, Thin Layer; Dogs

1970
Interaction of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC 79037) with nucleic acids and proteins in vivo and in vitro.
    Cancer research, 1972, Volume: 32, Issue:1

    Topics: Alkylating Agents; Animals; Brain; Carbon Isotopes; Cyclohexanes; Cytochromes; DNA; DNA, Neoplasm; H

1972
Enhancement of the antitumor effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and cyclophosphamide by vitamin A.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:4

    Topics: Alkylating Agents; Animals; Carmustine; Cell Membrane; Cyclophosphamide; Drug Synergism; Hemolysis;

1972
Enhancement of the antitumor effect of 1,3-bis(2-chloroethyl)-1-nitrosourea by vitamin A and caffeine.
    Journal of the National Cancer Institute, 1972, Volume: 48, Issue:4

    Topics: Alkylating Agents; Animals; Caffeine; Carmustine; Cell Membrane; DNA Repair; Drug Combinations; Drug

1972
Structure-activity relationships: nitrosoureas.
    Cancer chemotherapy reports. Part 3, 1972, Volume: 3, Issue:1

    Topics: Animals; Antineoplastic Agents; Leukemia L1210; Lung Neoplasms; Nitroso Compounds; Nitrosourea Compo

1972
Selective metabolic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea upon de novo purine biosynthesis.
    Cancer research, 1971, Volume: 31, Issue:3

    Topics: Acute Disease; Amino Acids; Animals; Antineoplastic Agents; Ascitic Fluid; Carbon Isotopes; Carcinom

1971
Effects of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; NSC-79037) and its degradation products on progression of L1210 cells through the cell cycle.
    Cancer chemotherapy reports, 1971, Volume: 55, Issue:3

    Topics: Animals; Antineoplastic Agents; Autoradiography; Carbon Isotopes; Cyanates; Cyclohexanes; Cyclohexyl

1971
Differences in the immunogenicity of leukemia L1210 sublines in DBA-2 mice.
    Cancer research, 1971, Volume: 31, Issue:12

    Topics: Anilides; Animals; Antigens, Neoplasm; Antineoplastic Agents; Cell Line; Cytarabine; Female; Guanine

1971
Ion-dependent activation of dihydrofolate reductase from L1210 cells.
    Biochemistry, 1967, Volume: 6, Issue:11

    Topics: Animals; Binding Sites; Bromine; Chlorine; Folic Acid Antagonists; Hydrogen-Ion Concentration; Ions;

1967
Immunological alteration of leukemic cells in vivo after treatment with an antitumor drug.
    Proceedings of the National Academy of Sciences of the United States of America, 1970, Volume: 66, Issue:4

    Topics: Animals; Cyclophosphamide; Female; Imidazoles; Leukemia L1210; Longevity; Male; Mice; Nitroso Compou

1970
[The mechanism of the antitumor effect of nitrosopropylurea (NPU)].
    Voprosy onkologii, 1969, Volume: 15, Issue:11

    Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Formates; In Vitro T

1969
Effect of combined therapy with cytosine arabinoside (NSC-63878) and l,3-bis-(2-chloroethyl)-1-nitrosourea (NSC-409962) on sarcoma 180 and L1210 in vivo.
    Cancer chemotherapy reports, 1969, Volume: 53, Issue:4

    Topics: Animals; Cytarabine; DNA, Neoplasm; Drug Synergism; Female; Leukemia L1210; Mice; Neoplasms, Experim

1969
The effect of chemotherapy on the growth characteristics and cellular kinetics of leukemia L1210.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Division; Cyclophosphamide; DNA, Neop

1970
Comparative effects of the antitumor agents 5-(Dimethyltriazeno)-imidazole-4-carboxamide and 1,3-bis(2-chloroethyl)-1-nitrosourea on cell cycle of L1210 leukemia cells in vivo.
    Cancer research, 1970, Volume: 30, Issue:8

    Topics: Amides; Animals; Antineoplastic Agents; Autoradiography; Biological Assay; DNA, Neoplasm; Imidazoles

1970
Effects of 4,4'-diacetyldiphenylurea-bis-(guanylhydrazone) on the incorporation of precursors into nucleic acid and protein of leukemia L1210.
    Cancer research, 1970, Volume: 30, Issue:8

    Topics: Animals; Carbon Isotopes; Culture Techniques; Depression, Chemical; DNA Nucleotidyltransferases; DNA

1970
Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and some chemically related compounds upon the progression of cultured H.Ep. no. 2 cells through the cell cycle.
    Cancer research, 1970, Volume: 30, Issue:6

    Topics: Animals; Benzocycloheptenes; Carcinoma; Cell Division; Cell Line; Culture Techniques; Cyanates; Ethy

1970
Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds upon the synthesis of DNA by cell-free systems.
    Cancer research, 1968, Volume: 28, Issue:1

    Topics: Animals; Cell-Free System; DNA, Neoplasm; Histocytochemistry; Leukemia L1210; Mice; Neoplasm Transpl

1968
Effects of 4,4'-diacetyl-diphenyl-urea-bis(guanylhydrazone) on leukemia L1210.
    Cancer research, 1968, Volume: 28, Issue:2

    Topics: Animals; Antineoplastic Agents; Cytarabine; Drug Synergism; Female; Hydrazines; Injections, Intraper

1968
Effect of treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or cyclophosphamide on spleen colony-forming units and survival time of leukemic mice.
    Cancer research, 1968, Volume: 28, Issue:7

    Topics: Animals; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Leukemia L1210; Mice; Nitroso Compounds;

1968
1,3-bis(2-chloroethyl)-1-nitrosourea (NSC-409962) and methotrexate (NSC-740) as combination therapy for advanced mouse leukemia L1210.
    Cancer chemotherapy reports, 1965, Volume: 48

    Topics: Animals; Female; Leukemia L1210; Male; Methotrexate; Mice; Nitroso Compounds; Urea

1965
Some effects of 1, 3-bis(2-chloroethyl)-1-nitrosourea upon the synthesis of protein and nucleic acids in vivo and in vitro.
    Cancer research, 1965, Volume: 25, Issue:10

    Topics: Alkylating Agents; Animals; Carbon Isotopes; Cricetinae; DNA; DNA, Neoplasm; Female; In Vitro Techni

1965
Effects of hydroxyurea and related compounds on the blood and marrow of experimental animals.
    Cancer research, 1966, Volume: 26, Issue:11

    Topics: Adrenal Glands; Animals; Antineoplastic Agents; Blood Cell Count; Blood Cells; Body Weight; Hydroxyu

1966
The synthesis of potential anticancer agents. XXXVI. N-nitrosoureas. II. Haloalkyl derivatives.
    Journal of medicinal chemistry, 1966, Volume: 9, Issue:6

    Topics: Animals; Antineoplastic Agents; Chemistry, Organic; Infrared Rays; Leukemia L1210; Mice; Nitroso Com

1966