Page last updated: 2024-10-21

urea and Leukemia L 1210

urea has been researched along with Leukemia L 1210 in 51 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research

Studies (51)

Timeframe	Studies, this research(%)	All Research%
pre-1990	47 (92.16)	18.7374
1990's	3 (5.88)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (1.96)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ren, F	1
Zhong, Y	1
Mai, X	1
Liao, YJ	1
Liu, C	1
Feng, LH	1
Sun, W	1
Zen, WB	1
Liu, WM	1
Liu, J	1
Jin, N	1
SCHABEL, FM	2
JOHNSTON, TP	4
McCALEB, GS	3
MONTGOMERY, JA	3
LASTER, WR	1
SKIPPER, HE	2
SCHRECKER, AW	1
HUENNEKENS, FM	3
STEARNS, B	1
LOSEE, KA	1
BERNSTEIN, J	1
ADAMSON, RH	3
Tyrer, DD	3
Kline, I	3
Venditti, JM	3
Goldin, A	6
Nelson, HG	1
Shelton, FJ	1
Wetzel, WH	1
Wilkoff, LJ	1
Dixon, GJ	1
Dulmadge, EA	1
Cates, LA	1
Cress, AE	1
Bowden, GT	1
Konstantinov, S	1
Topashka-Ancheva, M	1
Karaivanova, M	1
Zoneva, G	1
Galova, I	1
Walker, DL	1
Reid, JM	1
Ames, MM	1
Fukutomi, R	1
Kagechika, H	1
Hashimoto, Y	1
Shudo, K	1
Fuji, H	1
Mihich, E	6
Duffy, TH	1
Beckman, SB	1
Peterson, SM	1
Vitols, KS	1
Schein, PS	1
Gorbacheva, LB	2
Kukushkina, GV	2
McCullough, JL	1
Bertino, JR	1
Denny, GH	1
Ryder, MA	1
Gang, M	1
Artis, EW	1
Dave, C	3
Ashton, WT	1
Kirk, LL	1
Baker, BR	1
Ehrke, J	1
Korytnyk, W	1
Ghosh, AC	1
Angelino, N	1
Ringertz, NR	1
Bolund, L	1
Oliverio, VT	2
Vietzke, WM	1
Williams, MK	1
Cheng, CJ	1
Fujimura, S	1
Grunberger, D	1
Weinstein, IB	1
Cohen, MH	2
Carbone, PP	1
Groth, DP	1
D'Angelo, JM	1
Vogler, WR	1
Mingioli, ES	1
Betz, B	1
Bray, DA	1
DeVita, VT	2
Kitano, M	1
Reyes, P	1
Bonmassar, E	1
Bonmassar, A	1
Vadlamudi, S	2
Sokolova, IS	1
Mizuno, NS	1
Humphrey, EW	1
Young, RC	1
Shirakawa, S	1
Frei, E	1
Soucek, J	1
Ehrke, MJ	1
Wheeler, GP	3
Bowdon, BJ	3
Adamson, DJ	1
Vail, MH	1
Mulhern, AI	1
Waravdekar, VS	1
Choudry, JN	1
Lerner, LJ	1
Bianchi, A	1
Yiacas, E	1
Borman, A	1
Opliger, PS	1

Reviews

1 review available for urea and Leukemia L 1210

Article	Year
Factors pertaining to complete drug-induced remission of tumor in animals and man. Cancer research, 1969, Volume: 29, Issue:12 Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Cytarabine; Humans; Leukemia L1210; Methotrexate;	1969

Other Studies

50 other studies available for urea and Leukemia L 1210

Article	Year
Synthesis and anticancer evaluation of benzyloxyurea derivatives. Chemical & pharmaceutical bulletin, 2014, Volume: 62, Issue:9 Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; K562 Cells; Leukemia L1210	2014
Experimental evaluation of potential anticancer agents VIII. Effects of certain nitrosoureas on intracerebral L1210 leukemia. Cancer research, 1963, Volume: 23 Topics: Alkylating Agents; Animals; Antineoplastic Agents; Brain Neoplasms; Leukemia L1210; Nitroso Compound	1963
FURTHER OBSERVATIONS OF THE BINDING AND INHIBITION OF DIHYDROFOLIC REDUCTASE BY FOLIC ACID ANTAGONISTS. Biochemical pharmacology, 1964, Volume: 13 Topics: Aminopterin; Animals; Chromatography; Dialysis; Enzyme Inhibitors; Folic Acid; Folic Acid Antagonist	1964
THE SYNTHESIS OF ANTINEOPLASTIC AGENTS. XXXII. N-NITROSOUREAS. I. Journal of medicinal chemistry, 1963, Volume: 6 Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Leukemia L1210; Mice; Nitroso Compounds;	1963
HYDROXYUREA. A NEW TYPE OF POTENTIAL ANTITUMOR AGENT. Journal of medicinal chemistry, 1963, Volume: 6 Topics: Animals; Antineoplastic Agents; Hydroxyurea; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice;	1963
ACTIVITY OF CONGENERS OF HYDROXYUREA AGAINST ADVANCED LEUKEMIA L1210. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 119 Topics: Animals; Guanidine; Guanidines; Hydrazines; Hydroxylamines; Hydroxyurea; Leukemia L1210; Mice; Pharm	1965
Separate and sequential chemotherapy of mouse leukemia L1210 with 1-beta-D-arabinofuranosylcytosine hydrochloride and 1,3-bis(2-chloroethyl)-1-nitrosourea. Cancer research, 1967, Volume: 27, Issue:5 Topics: Animals; Cytarabine; Injections; Leukemia L1210; Longevity; Mice; Nitroso Compounds; Urea	1967
Potential carcinostatic agents. I. Derivatives and analogs of 1-(2-hydroxyethyl)-3-(4-tolyl)urea. Journal of medicinal chemistry, 1967, Volume: 10, Issue:4 Topics: Animals; Carcinoma; Chemistry, Organic; Leukemia L1210; Lung Neoplasms; Mice; Neoplasms, Experimenta	1967
Effect of 1,3-bis(2-chlorethyl)-1-nitrosourea (NSC-409962) and nitrogen mustard (NSC-762) on kinetic behavior of cultured L1210 leukemic cells. Cancer chemotherapy reports, 1967, Volume: 51, Issue:1 Topics: Alkylating Agents; Animals; Biological Assay; Culture Techniques; Kinetics; Leukemia L1210; Mechlore	1967
Phosphorus-nitrogen compounds. VII. Urea, aziridinecarboxamide, and semicarbazide derivatives. Journal of medicinal chemistry, 1967, Volume: 10, Issue:5 Topics: Amides; Animals; Antimalarials; Antineoplastic Agents; Azirines; Carcinoma 256, Walker; Leukemia L12	1967
Criteria associated with destruction of leukemia and solid tumor cells in animals. Cancer research, 1967, Volume: 27, Issue:12 Topics: Animals; Cricetinae; Cyclophosphamide; Cytarabine; Leukemia L1210; Methotrexate; Mice; Neoplasm Tran	1967
Covalent DNA-protein crosslinking occurs after hyperthermia and radiation. Radiation research, 1983, Volume: 95, Issue:3 Topics: Animals; Cell Line; DNA; Dose-Response Relationship, Radiation; Guanidine; Guanidines; Hot Temperatu	1983
Antitumor, nephrotoxic and clastogenic effect of cis-DDP with DDTC or NAC. Neoplasma, 1994, Volume: 41, Issue:5 Topics: Acetylcysteine; Animals; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Creatinine; Diti	1994
Preclinical pharmacology of bizelesin, a potent bifunctional analog of the DNA-binding antibiotic CC-1065. Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:4 Topics: Alkylating Agents; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Benzofurans; Chromat	1994
Novel aromatic urea derivatives with DNA-binding ability. Chemical & pharmaceutical bulletin, 1996, Volume: 44, Issue:10 Topics: Animals; Anti-Bacterial Agents; Cattle; Cell Division; DNA; Humans; KB Cells; Kinetics; Leukemia L12	1996
Selection for high immunogenicity in drug-resistant sublines of murine lymphomas demonstrated by plaque assay. Cancer research, 1975, Volume: 35, Issue:4 Topics: Animals; Antibodies, Neoplasm; Antibody-Producing Cells; Antigens, Neoplasm; Antineoplastic Agents;	1975
L1210 dihydrofolate reductase. Kinetics and mechanism of activation by various agents. The Journal of biological chemistry, 1987, May-25, Volume: 262, Issue:15 Topics: Animals; Cell Line; Chloromercuribenzoates; Dithionitrobenzoic Acid; Enzyme Activation; Guanidine; G	1987
1-methyl-1-nitrosourea and dialkylnitrosamine depression of nicotinamide adenine dinucleotide. Cancer research, 1969, Volume: 29, Issue:6 Topics: Animals; Depression, Chemical; Leukemia L1210; Liver; Male; N-Glycosyl Hydrolases; NAD; Niacinamide;	1969
Some aspects of the mechanism of action of 1-propyl-1-nitrosourea. Biochemical pharmacology, 1970, Volume: 19, Issue:5 Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular	1970
Dihydrofolate reductase from mouse liver and spleen. Purification, properties and inhibition by substituted 2,4-diaminopyrimidines and 4,6-diaminotriazines. Biochemical pharmacology, 1971, Volume: 20, Issue:3 Topics: Animals; Antigen-Antibody Reactions; Cell Line; Chromatography; Chromatography, Gel; Enzyme Activati	1971
Alpha-(Ureidomethylene)lactones and derived 5-(hydroxyalkyl)uracils. Journal of medicinal chemistry, 1974, Volume: 17, Issue:11 Topics: Animals; Lactones; Leukemia L1210; Spectrophotometry, Ultraviolet; Uracil; Urea	1974
Evaluation of antileukemic agents in advanced leukemia L1210 in mice. X. Cancer chemotherapy reports. Part 2, 1972, Volume: 3, Issue:1 Topics: Alkylating Agents; Amides; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Cytarabine;	1972
Uptake and intracellular distribution of 4,4'-diacetyldiphenylurea-bis-(Guanylhydrazone) in sensitive and resistant leukemia L1210 cells. Biochemical pharmacology, 1972, Oct-15, Volume: 21, Issue:20 Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cell Line; Cell Membrane; Cell Nucleus; Centrifugat	1972
Irreversible enzyme inhibitors. 198. Diaminodihydro-S-triazines and diaminopyrimidines bearing substituted (ureidomethyl)phenyl substituents as reversible inhibitors of dihydrofolate reductase. Journal of medicinal chemistry, 1973, Volume: 16, Issue:5 Topics: Animals; Carbamates; Cell Survival; Cells, Cultured; Folic Acid Antagonists; Leukemia L1210; Methods	1973
Mechanism of the inhibition of DNA biosynthesis by 4,4'-diacetyldiphenylurea-bis(guanylhydrazone) in leukemia L1210 cells. Cancer research, 1973, Volume: 33, Issue:9 Topics: Animals; Antineoplastic Agents; Carbon Isotopes; Cell-Free System; Cells, Cultured; DNA Nucleotidylt	1973
Guanylhydrazones with potential antileukemic activity. 1. Aza analogs of 4,4'-diacetyldiphenylurea bis(guanylhydrazone). Journal of medicinal chemistry, 1973, Volume: 16, Issue:8 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Aza Compounds; DNA Nucleotidyltransferases; DNA, Neo	1973
Actinomycin binding capacity of deoxyribonucleoprotein. Biochimica et biophysica acta, 1969, Jan-21, Volume: 174, Issue:1 Topics: Animals; Animals, Newborn; Binding Sites; Calcium; Cattle; Chemical Phenomena; Chemistry; Chickens;	1969
The absorption, distribution, excretion, and biotransformation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea in animals. Cancer research, 1970, Volume: 30, Issue:5 Topics: Animals; Antineoplastic Agents; Biotransformation; Carbon Isotopes; Chromatography, Thin Layer; Dogs	1970
Interaction of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (NSC 79037) with nucleic acids and proteins in vivo and in vitro. Cancer research, 1972, Volume: 32, Issue:1 Topics: Alkylating Agents; Animals; Brain; Carbon Isotopes; Cyclohexanes; Cytochromes; DNA; DNA, Neoplasm; H	1972
Enhancement of the antitumor effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and cyclophosphamide by vitamin A. Journal of the National Cancer Institute, 1972, Volume: 48, Issue:4 Topics: Alkylating Agents; Animals; Carmustine; Cell Membrane; Cyclophosphamide; Drug Synergism; Hemolysis;	1972
Enhancement of the antitumor effect of 1,3-bis(2-chloroethyl)-1-nitrosourea by vitamin A and caffeine. Journal of the National Cancer Institute, 1972, Volume: 48, Issue:4 Topics: Alkylating Agents; Animals; Caffeine; Carmustine; Cell Membrane; DNA Repair; Drug Combinations; Drug	1972
Structure-activity relationships: nitrosoureas. Cancer chemotherapy reports. Part 3, 1972, Volume: 3, Issue:1 Topics: Animals; Antineoplastic Agents; Leukemia L1210; Lung Neoplasms; Nitroso Compounds; Nitrosourea Compo	1972
Selective metabolic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea upon de novo purine biosynthesis. Cancer research, 1971, Volume: 31, Issue:3 Topics: Acute Disease; Amino Acids; Animals; Antineoplastic Agents; Ascitic Fluid; Carbon Isotopes; Carcinom	1971
Effects of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; NSC-79037) and its degradation products on progression of L1210 cells through the cell cycle. Cancer chemotherapy reports, 1971, Volume: 55, Issue:3 Topics: Animals; Antineoplastic Agents; Autoradiography; Carbon Isotopes; Cyanates; Cyclohexanes; Cyclohexyl	1971
Differences in the immunogenicity of leukemia L1210 sublines in DBA-2 mice. Cancer research, 1971, Volume: 31, Issue:12 Topics: Anilides; Animals; Antigens, Neoplasm; Antineoplastic Agents; Cell Line; Cytarabine; Female; Guanine	1971
Ion-dependent activation of dihydrofolate reductase from L1210 cells. Biochemistry, 1967, Volume: 6, Issue:11 Topics: Animals; Binding Sites; Bromine; Chlorine; Folic Acid Antagonists; Hydrogen-Ion Concentration; Ions;	1967
Immunological alteration of leukemic cells in vivo after treatment with an antitumor drug. Proceedings of the National Academy of Sciences of the United States of America, 1970, Volume: 66, Issue:4 Topics: Animals; Cyclophosphamide; Female; Imidazoles; Leukemia L1210; Longevity; Male; Mice; Nitroso Compou	1970
[The mechanism of the antitumor effect of nitrosopropylurea (NPU)]. Voprosy onkologii, 1969, Volume: 15, Issue:11 Topics: Amino Acids; Animals; Carbon Isotopes; Carcinoma, Ehrlich Tumor; DNA, Neoplasm; Formates; In Vitro T	1969
Effect of combined therapy with cytosine arabinoside (NSC-63878) and l,3-bis-(2-chloroethyl)-1-nitrosourea (NSC-409962) on sarcoma 180 and L1210 in vivo. Cancer chemotherapy reports, 1969, Volume: 53, Issue:4 Topics: Animals; Cytarabine; DNA, Neoplasm; Drug Synergism; Female; Leukemia L1210; Mice; Neoplasms, Experim	1969
The effect of chemotherapy on the growth characteristics and cellular kinetics of leukemia L1210. Cancer research, 1970, Volume: 30, Issue:6 Topics: Animals; Bone Marrow; Bone Marrow Cells; Carbon Isotopes; Cell Division; Cyclophosphamide; DNA, Neop	1970
Comparative effects of the antitumor agents 5-(Dimethyltriazeno)-imidazole-4-carboxamide and 1,3-bis(2-chloroethyl)-1-nitrosourea on cell cycle of L1210 leukemia cells in vivo. Cancer research, 1970, Volume: 30, Issue:8 Topics: Amides; Animals; Antineoplastic Agents; Autoradiography; Biological Assay; DNA, Neoplasm; Imidazoles	1970
Effects of 4,4'-diacetyldiphenylurea-bis-(guanylhydrazone) on the incorporation of precursors into nucleic acid and protein of leukemia L1210. Cancer research, 1970, Volume: 30, Issue:8 Topics: Animals; Carbon Isotopes; Culture Techniques; Depression, Chemical; DNA Nucleotidyltransferases; DNA	1970
Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and some chemically related compounds upon the progression of cultured H.Ep. no. 2 cells through the cell cycle. Cancer research, 1970, Volume: 30, Issue:6 Topics: Animals; Benzocycloheptenes; Carcinoma; Cell Division; Cell Line; Culture Techniques; Cyanates; Ethy	1970
Effects of 1,3-bis(2-chloroethyl)-1-nitrosourea and related compounds upon the synthesis of DNA by cell-free systems. Cancer research, 1968, Volume: 28, Issue:1 Topics: Animals; Cell-Free System; DNA, Neoplasm; Histocytochemistry; Leukemia L1210; Mice; Neoplasm Transpl	1968
Effects of 4,4'-diacetyl-diphenyl-urea-bis(guanylhydrazone) on leukemia L1210. Cancer research, 1968, Volume: 28, Issue:2 Topics: Animals; Antineoplastic Agents; Cytarabine; Drug Synergism; Female; Hydrazines; Injections, Intraper	1968
Effect of treatment with 1,3-bis(2-chloroethyl)-1-nitrosourea or cyclophosphamide on spleen colony-forming units and survival time of leukemic mice. Cancer research, 1968, Volume: 28, Issue:7 Topics: Animals; Bone Marrow; Bone Marrow Cells; Cyclophosphamide; Leukemia L1210; Mice; Nitroso Compounds;	1968
1,3-bis(2-chloroethyl)-1-nitrosourea (NSC-409962) and methotrexate (NSC-740) as combination therapy for advanced mouse leukemia L1210. Cancer chemotherapy reports, 1965, Volume: 48 Topics: Animals; Female; Leukemia L1210; Male; Methotrexate; Mice; Nitroso Compounds; Urea	1965
Some effects of 1, 3-bis(2-chloroethyl)-1-nitrosourea upon the synthesis of protein and nucleic acids in vivo and in vitro. Cancer research, 1965, Volume: 25, Issue:10 Topics: Alkylating Agents; Animals; Carbon Isotopes; Cricetinae; DNA; DNA, Neoplasm; Female; In Vitro Techni	1965
Effects of hydroxyurea and related compounds on the blood and marrow of experimental animals. Cancer research, 1966, Volume: 26, Issue:11 Topics: Adrenal Glands; Animals; Antineoplastic Agents; Blood Cell Count; Blood Cells; Body Weight; Hydroxyu	1966
The synthesis of potential anticancer agents. XXXVI. N-nitrosoureas. II. Haloalkyl derivatives. Journal of medicinal chemistry, 1966, Volume: 9, Issue:6 Topics: Animals; Antineoplastic Agents; Chemistry, Organic; Infrared Rays; Leukemia L1210; Mice; Nitroso Com	1966