Page last updated: 2024-10-20

urea and Leishmaniasis, Visceral

urea has been researched along with Leishmaniasis, Visceral in 15 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Leishmaniasis, Visceral: A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African.

Research Excerpts

ExcerptRelevanceReference
"The application of RF07 in the treatment of visceral leishmaniasis suggests that it is an alternative to the disease, since the reversal of clinical signs in dogs with VL requires the use of 0."1.56preADMET analysis and clinical aspects of dogs treated with the Organotellurium compound RF07: A possible control for canine visceral leishmaniasis? ( Braz, DC; Cunha, RLOR; das Chagas Pereira de Andrade, F; de Amorim Carvalho, FA; de Carvalho Maia, OA; Filgueiras, LA; Maia Filho, ALM; Mendes, AN; Rodezno, SVA; Viana Nunes, AM, 2020)
"Visceral leishmaniasis is a severe parasitic disease that is one of the most neglected tropical diseases."1.42Novel Amino-pyrazole Ureas with Potent In Vitro and In Vivo Antileishmanial Activity. ( Braillard, S; Brown, AD; Cao, Y; Feijens, PB; Gardner, JM; Gibson, KR; Glossop, PA; Hua, W; Maes, LJ; Matheeussen, A; Mills, JE; Morgans, GL; Mowbray, CE; Speed, W; Whitlock, GA, 2015)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's4 (26.67)18.2507
2000's0 (0.00)29.6817
2010's4 (26.67)24.3611
2020's2 (13.33)2.80

Authors

AuthorsStudies
de Jong, MK1
Rappoldt, A1
Broere, F1
Piek, CJ1
Viana Nunes, AM1
das Chagas Pereira de Andrade, F1
Filgueiras, LA1
de Carvalho Maia, OA1
Cunha, RLOR1
Rodezno, SVA1
Maia Filho, ALM1
de Amorim Carvalho, FA1
Braz, DC1
Mendes, AN1
Killick-Kendrick, R1
Asad, M1
Bhattacharya, P1
Banerjee, A1
Ali, N1
Mowbray, CE1
Braillard, S1
Speed, W1
Glossop, PA1
Whitlock, GA1
Gibson, KR1
Mills, JE1
Brown, AD1
Gardner, JM1
Cao, Y1
Hua, W1
Morgans, GL1
Feijens, PB1
Matheeussen, A1
Maes, LJ1
Pessoa-E-Silva, R1
Mendonça Trajano-Silva, LA1
Lopes da Silva, MA1
da Cunha Gonçalves-de-Albuquerque, S1
de Goes, TC1
Silva de Morais, RC1
Lopes de Melo, F1
de Paiva-Cavalcanti, M1
CHEN, TT1
HO, EA1
SOONG, TH1
LI, Y1
Medda, S1
Mukherjee, S1
Das, N2
Naskar, K2
Mahato, SB3
Basu, MK2
Al-Saffar, NR1
Al-Mudhaffer, SA1
Prasad, LS1
Sen, S1
Ganguly, SK1
Ghosh, DK3
Ghosh, AK2
Mukerji, K2
Pal, BC1
Khan, S1
Brahmachari, UN1

Other Studies

15 other studies available for urea and Leishmaniasis, Visceral

ArticleYear
Survival time and prognostic factors in canine leishmaniosis in a non-endemic country treated with a two-phase protocol including initial allopurinol monotherapy.
    Parasites & vectors, 2023, May-15, Volume: 16, Issue:1

    Topics: Allopurinol; Animals; Creatinine; Dog Diseases; Dogs; Humans; Leishmania infantum; Leishmaniasis; Le

2023
preADMET analysis and clinical aspects of dogs treated with the Organotellurium compound RF07: A possible control for canine visceral leishmaniasis?
    Environmental toxicology and pharmacology, 2020, Volume: 80

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antiprotozoal Agents; Aspartate Aminotransferas

2020
The race to discover the insect vector of kala-azar: a great saga of tropical medicine 1903-1942.
    Bulletin de la Societe de pathologie exotique (1990), 2013, Volume: 106, Issue:2

    Topics: Animals; Antiprotozoal Agents; History, 20th Century; Humans; India; Insect Bites and Stings; Insect

2013
Therapeutic and immunomodulatory activities of short-course treatment of murine visceral leishmaniasis with KALSOME™10, a new liposomal amphotericin B.
    BMC infectious diseases, 2015, Apr-17, Volume: 15

    Topics: Amphotericin B; Animals; Antiprotozoal Agents; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocyte

2015
Novel Amino-pyrazole Ureas with Potent In Vitro and In Vivo Antileishmanial Activity.
    Journal of medicinal chemistry, 2015, Dec-24, Volume: 58, Issue:24

    Topics: Animals; Antiparasitic Agents; Cricetinae; Female; Humans; Leishmania donovani; Leishmania infantum;

2015
Evaluation of urine for Leishmania infantum DNA detection by real-time quantitative PCR.
    Journal of microbiological methods, 2016, Volume: 131

    Topics: Acquired Immunodeficiency Syndrome; Adolescent; Adult; Aged; Brazil; Child; Creatinine; DNA, Kinetop

2016
Rapid treatment of Chinese kala-azar with urea stibamine; a report of 12 cases.
    Annals of tropical medicine and parasitology, 1949, Volume: 43, Issue:2

    Topics: Humans; Leishmaniasis; Leishmaniasis, Visceral; Organometallic Compounds; Urea

1949
Rate of disappearance of Leishmania in kala-azar patients under urea stibamine therapy.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1949, Volume: 42, Issue:6

    Topics: Humans; Leishmania; Leishmaniasis; Leishmaniasis, Visceral; Organometallic Compounds; Urea

1949
Sugar-coated liposomes: a novel delivery system for increased drug efficacy and reduced drug toxicity.
    Biotechnology and applied biochemistry, 1993, Volume: 17, Issue:1

    Topics: Animals; Antiprotozoal Agents; Cricetinae; Disease Models, Animal; Drug Carriers; Drug Compounding;

1993
Lactate dehydrogenase and other enzymes in kala-azar patients in Iraq.
    The Indian journal of medical research, 1979, Volume: 70

    Topics: Alanine Transaminase; Aspartate Aminotransferases; Child, Preschool; Creatine Kinase; Humans; Hydrox

1979
Renal involvement in kala-azar.
    The Indian journal of medical research, 1992, Volume: 95

    Topics: Animals; Cricetinae; Female; Glomerular Filtration Rate; Humans; Kidney; Kidney Diseases; Leishmania

1992
Targeting of urea stibamine encapsulated in liposomes to reticuloendothelial system for the treatment of experimental leishmaniasis.
    Biochemical medicine and metabolic biology, 1990, Volume: 43, Issue:2

    Topics: Animals; Antiprotozoal Agents; Cricetinae; Drug Carriers; Leishmaniasis, Visceral; Liposomes; Mannos

1990
Effect of ureastibamine on Leishmania donovani amastigote.
    The Indian journal of medical research, 1990, Volume: 91

    Topics: Animals; Antiprotozoal Agents; Cricetinae; Disease Models, Animal; Leishmania donovani; Leishmaniasi

1990
Urea stibamine: an improved method of preparation and its antileishmanial activity.
    Biochemical medicine and metabolic biology, 1987, Volume: 38, Issue:1

    Topics: Animals; Antimony; Antiprotozoal Agents; Cricetinae; DNA Replication; Glycolysis; Indicators and Rea

1987
Chemotherapy of antimonial compounds in kala-azar infection. Part IV. Further observations on the therapeutic values of urea stibamine. By U.N. Brahmachari, 1922.
    The Indian journal of medical research, 1989, Volume: 89

    Topics: Antimony; Antiprotozoal Agents; History, 20th Century; Humans; Leishmaniasis, Visceral; Organometall

1989