Page last updated: 2024-10-21

urea and Kidney, Polycystic

urea has been researched along with Kidney, Polycystic in 26 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

ExcerptRelevanceReference
"Methods The clinical data of ESRD patient whose primary diagnosis was PKD in Peking Union Medical College Hospital were retrospectively collected from January 1993 to December 2015."1.46Effectiveness of Peritoneal Dialysis in Treating Adult End Stage Renal Disease Patients with Polycystic Kidney Disease. ( Chen, LM; Li, XM; Li, Y; Liu, BY; Ma, Y; Wang, HY; Xia, JH; Yang, W; Zhou, ZJ, 2017)
"Thus, the polycystic kidney produces FGF23 but is resistant to its action."1.40Renal expression of FGF23 and peripheral resistance to elevated FGF23 in rodent models of polycystic kidney disease. ( Biber, J; Edenhofer, I; Jaeger, P; Mohebbi, N; Pavik, I; Petzold, K; Saleh, L; Segerer, S; Serra, AL; Spichtig, D; Stange, G; Wagner, CA; Zhang, H, 2014)
"Polycystic kidney disease is the most common potentially lethal single- gene inherited disease in man."1.29Amelioration of polycystic kidney disease by modification of dietary protein intake in the rat. ( Ogborn, MR; Sareen, S, 1995)
"Pyelonephritis was a very common complication, but was present only in patients from groups 2 and 3, in whom a lumen was present in the draining ureter, and not in patients from group 1 in whom the ureter was atretic or absent, and the kidney not functioning."1.25Renal dysplasia. I. A clinico-pathological study of 76 cases. ( Risdon, RA, 1971)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199016 (61.54)18.7374
1990's3 (11.54)18.2507
2000's3 (11.54)29.6817
2010's4 (15.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ma, Y1
Wang, HY1
Zhou, ZJ1
Li, Y1
Yang, W1
Liu, BY1
Xia, JH1
Li, XM1
Chen, LM1
Spichtig, D1
Zhang, H1
Mohebbi, N1
Pavik, I1
Petzold, K1
Stange, G1
Saleh, L1
Edenhofer, I1
Segerer, S1
Biber, J1
Jaeger, P1
Serra, AL1
Wagner, CA1
Grotemeyer, D1
Voiculescu, A1
Iskandar, F1
Voshege, M1
Blondin, D1
Balzer, KM1
Rump, LC1
Sandmann, W1
Bhimani, JP1
Ouseph, R1
Ward, RA1
Wiedmeyer, CE1
Royal, AB1
SALISBURY, PF1
POMERANZ, AA1
DUNEA, G1
KOLFF, WJ1
Nosková-Lyerová, L1
Viklický, O1
Schück, O1
Ward, JN1
Draper, JW1
Lavengood, RW1
Mowat, AP1
Barsotti, G1
Cupisti, A1
Moriconi, L1
Cozza, V1
Falbo, E1
Gattai, V1
Pozzolini, L1
Meola, M1
Ogborn, MR1
Sareen, S1
Riedel, E1
Nündel, M1
Hampl, H1
Jayapalan, S1
Saboorian, MH1
Edmunds, JW1
Aukema, HM1
Selgas, R1
Muñoz, J1
Miranda, B1
Ramos, P1
Caparros, G1
Revuelta, KL1
Gonzalez, A1
Gallar, P1
Sanchez Sicilia, L1
Wright, FW1
Ledingham, JG1
Dunnill, MS1
Grieve, NW1
Pohl, JE1
Thurston, H1
Swales, JD1
Milman, N1
Mazo, EB1
Saxton, HM1
Cameron, JS1
Chantler, C1
Ogg, CS1
Caissel, J1
Hall, GH1
Holman, HM1
Webster, AD1
Risdon, RA1
Berlyne, GM1
Gaan, D1
Ginks, WR1
Blagg, CR1
Kemble, F1
Taverner, D1
Gardner, KD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect Of Dialysate Flow Rate On Mass Transfer Coefficient - Area (KoA) In Dialyzers With Different Membrane Packing Densities[NCT00636077]12 participants (Actual)Interventional2008-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Effect of Increased Dialysate Flow Rate on KoA for b2-microglobulin Between 4 Dialyzers With Different Membrane Packing Densities.

(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)

,,,
InterventionKoA for b2-microglobulin (mL/min) (Mean)
350 mL/min Dialysate Flow Rate500 mL/min Dialysate Flow Rate800 mL/min Dialysate Flow Rate
F160NR272831
F200NR272521
HD-C4 Big656264
HD-C4 Small615756

Effect of Increased Dialysate Flow Rate on KoA for Phosphorus Between 4 Dialyzers With Different Membrane Packing Densities.

(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)

,,,
InterventionKoA for Phosphorus (mL/min) (Mean)
350 mL/min Dialysate Flow Rate500 mL/min Dialysate Flow Rate800 mL/min Dialysate Flow Rate
F160NR434450458
F200NR504491560
HD-C4 Big434435520
HD-C4 Small334422415

Effect of Increased Dialysate Flow Rate on KoA for Urea Between 4 Dialyzers With Different Membrane Packing Densities.

KoA is a constant that describes the efficiency of a dialyzer in removing urea. KoA is determined by surface area of the membrane, the thickness of the membrane and pore size. (NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)

,,,
InterventionKoA for urea (mL/min) (Mean)
350 mL/min Dialysate Flow Rate500 mL/min Dialysate Flow Rate800 mL/min Dialysate Flow Rate
F160NR770738809
F200NR798890817
HD-C4 Big844898922
HD-C4 Small763748761

Effect of Increased Dialysate Flow Rate on Whole Blood B2-microglobulin Clearance Between 4 Dialyzers With Different Membrane Packing Densities.

(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)

,,,
Interventionwhole blood clearance B2-microglobulin (Mean)
350 mL/min Dialysate Flow Rate500 mL/min Dialysate Flow Rate800 mL/min Dialysate Flow Rate
F160NR878678
F200NR726575
HD-C4 Big106129118
HD-C4 Small119118121

Effect of Increased Dialysate Flow Rate on Whole Blood Phosphorus Clearance Between 4 Dialyzers With Different Membrane Packing Densities.

(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)

,,,
Interventionwhole blood phosphorus clearance mL/min (Mean)
350 mL/min Dialysate Flow Rate500 mL/min Dialysate Flow Rate800 mL/min Dialysate Flow Rate
F160NR247260272
F200NR249265281
HD-C4 Big255269286
HD-C4 Small252261273

Effect of Increased Dialysate Flow Rate on Whole Blood Urea Clearance Between 4 Dialyzers With Different Membrane Packing Densities.

(NCT00636077)
Timeframe: During the third treatment with each dialyzer (one time during each trial period week)

,,,
InterventionWhole blood urea clearance (mL/min) (Mean)
350 mL/min Dialysate Flow Rate500 mL/min Dialysate Flow Rate800 mL/min Dialysate Flow Rate
F160NR271293313
F200NR274313327
HD-C4 Big279315340
HD-C4 Small270295320

Reviews

1 review available for urea and Kidney, Polycystic

ArticleYear
Hepatic Disorders.
    Clinics in gastroenterology, 1982, Volume: 11, Issue:1

    Topics: Adolescent; Adult; alpha 1-Antitrypsin Deficiency; Amino Acid Metabolism, Inborn Errors; Ammonia; Ch

1982

Trials

1 trial available for urea and Kidney, Polycystic

ArticleYear
alpha-Ketoglutarate application in hemodialysis patients improves amino acid metabolism.
    Nephron, 1996, Volume: 74, Issue:2

    Topics: Adult; Aged; Amino Acids; Calcium Carbonate; Chromatography, High Pressure Liquid; Female; Glomerulo

1996

Other Studies

24 other studies available for urea and Kidney, Polycystic

ArticleYear
Effectiveness of Peritoneal Dialysis in Treating Adult End Stage Renal Disease Patients with Polycystic Kidney Disease.
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2017, Aug-20, Volume: 39, Issue:4

    Topics: Adult; Creatinine; Female; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Male; Middle

2017
Renal expression of FGF23 and peripheral resistance to elevated FGF23 in rodent models of polycystic kidney disease.
    Kidney international, 2014, Volume: 85, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Animals; Biomarkers; Calcitriol; Calcium; Creatinine; Disease

2014
Renal cysts in living donor kidney transplantation: long-term follow-up in 25 patients.
    Transplantation proceedings, 2009, Volume: 41, Issue:10

    Topics: Adult; Aged; Creatinine; Female; Follow-Up Studies; Functional Laterality; Humans; Kidney Transplant

2009
Effect of increasing dialysate flow rate on diffusive mass transfer of urea, phosphate and beta2-microglobulin during clinical haemodialysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2010, Volume: 25, Issue:12

    Topics: beta 2-Microglobulin; Cross-Over Studies; Dialysis Solutions; Female; Glomerulonephritis; Humans; Hy

2010
Urinary biomarkers for monitoring disease progression in the Han:SPRD-cy rat model of autosomal-dominant polycystic kidney disease.
    Comparative medicine, 2010, Volume: 60, Issue:6

    Topics: Acetylglucosaminidase; Albuminuria; Animals; Biomarkers; Collagen Type IV; Creatinine; Disease Progr

2010
UREMIC TOXICITY CORRELATED WITH UNIDENTIFIED ANIONS.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1963, Volume: 114

    Topics: Anions; Blood Chemical Analysis; Creatine; Creatinine; Edema; Glomerulonephritis; Ileostomy; Kidney;

1963
CLINICAL EXPERIENCE WITH THE YATZIDIS CHARCOAL ARTIFICIAL KIDNEY.
    Transactions - American Society for Artificial Internal Organs, 1965, Volume: 11

    Topics: Blood Chemical Analysis; Blood Glucose; Blood Platelets; Calcium; Charcoal; Creatine; Creatinine; Gl

1965
[Hypernatraemia, increased protein intake and progression of renal insufficiency in a patient with polycystic renal degeneration].
    Vnitrni lekarstvi, 2001, Volume: 47, Issue:3

    Topics: Cerebral Hemorrhage; Dietary Proteins; Disease Progression; Diuresis; Humans; Hypernatremia; Male; M

2001
A clinical review of polycystic kidney disease in 53 patients.
    The Journal of urology, 1967, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Angiography; Child; Child, Preschool; Diagnosis, Differential; Female; Hema

1967
Effects of reduced protein intake in rats with congenital polycystic kidney without renal failure.
    Contributions to nephrology, 1995, Volume: 115

    Topics: Animals; Body Weight; Creatinine; Diet, Protein-Restricted; Disease Progression; Male; Polycystic Ki

1995
Amelioration of polycystic kidney disease by modification of dietary protein intake in the rat.
    Journal of the American Society of Nephrology : JASN, 1995, Volume: 6, Issue:6

    Topics: Animals; Creatinine; Diet, Protein-Restricted; Dietary Proteins; Male; Polycystic Kidney Diseases; R

1995
High dietary fat intake increases renal cyst disease progression in Han:SPRD-cy rats.
    The Journal of nutrition, 2000, Volume: 130, Issue:9

    Topics: Animals; Body Weight; Dietary Fats; Disease Models, Animal; Estradiol; Female; Male; Organ Size; Pol

2000
Induced changes of the peritoneal diffusion capacity by smoking, intraabdominal hypertension and omentectomy.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1989, Volume: 5

    Topics: Abdomen; Adult; Aged; Creatinine; Diabetic Nephropathies; Diffusion; Humans; Kidney Failure, Chronic

1989
Polycystic kidneys, renal hamartomas, their variants and complications.
    Clinical radiology, 1974, Volume: 25, Issue:1

    Topics: Acute Kidney Injury; Adult; Angiography; Blood Pressure; Creatinine; Diagnosis, Differential; Female

1974
Hypertension with renal impairment: influence of intensive therapy.
    The Quarterly journal of medicine, 1974, Volume: 43, Issue:172

    Topics: Adolescent; Adult; Chronic Disease; Creatinine; Diazoxide; Female; Glomerulonephritis; Humans; Hyper

1974
Blood transfusion requirements before and after bilateral nephrectomy in patients undergoing chronic hemodialysis.
    Acta medica Scandinavica, 1974, Volume: 195, Issue:6

    Topics: Adult; Antibodies; Blood Pressure; Blood Transfusion; Chronic Disease; Creatinine; Female; Glomerulo

1974
The role of arterial pressure dynamics in the diagnosis of renal graft rejection crisis.
    International urology and nephrology, 1972, Volume: 4, Issue:1

    Topics: Adult; Arteries; Blood Pressure; Body Temperature; Cadaver; Creatinine; Diuresis; Glomerulonephritis

1972
Renal puncture in infancy.
    British medical journal, 1973, Aug-04, Volume: 3, Issue:5874

    Topics: Female; Humans; Infant; Infant, Newborn; Kidney Diseases, Cystic; Male; Methods; Pneumothorax; Polyc

1973
[Renal failure in polycystic kidney (surgical treatment)].
    Journal d'urologie et de nephrologie, 1971, Volume: 77

    Topics: Adult; Creatinine; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Male; Methods; Polyc

1971
Anticoagulation by ancrod for haemodialysis.
    British medical journal, 1970, Dec-05, Volume: 4, Issue:5735

    Topics: Adult; Anticoagulants; Cellophane; Chronic Disease; Fibrin; Fibrinogen; Heparin; Humans; Leukocytes;

1970
Renal dysplasia. I. A clinico-pathological study of 76 cases.
    Journal of clinical pathology, 1971, Volume: 24, Issue:1

    Topics: Cartilage; Child; Child, Preschool; Chronic Disease; Epithelium; Female; Humans; Hydronephrosis; Inf

1971
Dietary treatment of chronic renal failure.
    The American journal of clinical nutrition, 1968, Volume: 21, Issue:6

    Topics: Acidosis; Creatinine; Diet Therapy; Dietary Proteins; Glomerular Filtration Rate; Glomerulonephritis

1968
Nerve conduction velocity in relationship to the severity of renal disease.
    Nephron, 1968, Volume: 5, Issue:4

    Topics: Adult; Amyloidosis; Creatinine; Female; Glomerulonephritis; Humans; Hypertension, Renal; Kidney Calc

1968
Composition of fluid in twelve cysts of a polycystic kidney.
    The New England journal of medicine, 1969, Oct-30, Volume: 281, Issue:18

    Topics: Adult; Amino Acids; Ammonia; Body Fluids; Calcium; Chromatography; Creatinine; Glucose; Humans; Hydr

1969