urea has been researched along with Itching in 24 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this pilot trial topical application of 10% Urea ISDIN ® plus dexpanthenol lotion has shown to improve skin dryness and pruritus in haemodialysis patients." | 9.15 | Efficacy of topical hydrating and emollient lotion containing 10% urea ISDIN® plus dexpanthenol (Ureadin Rx 10) in the treatment of skin xerosis and pruritus in hemodialyzed patients: an open prospective pilot trial. ( Castello, M; Milani, M, 2011) |
| "The analysis of the global estimation of severity of ichthyosis showed improvements being stronger in the body areas treated with Laceran 10% urea lotion (from 4." | 9.08 | Efficacy of urea therapy in children with ichthyosis. A multicenter randomized, placebo-controlled, double-blind, semilateral study. ( Bohnsack, K; Groll, S; Küster, W; Rippke, F; Traupe, H; Upmeyer, HJ, 1998) |
| "In an open multicentre drug monitoring survey, 1611 patients with atopic dermatitis, contact eczema, dry eczema, psoriasis and pruritus were treated with a preparation containing 5% urea and 3% polidocanol (laurylmacrogol)." | 7.69 | Results of a postmarketing drug monitoring survey with a polidocanol-urea preparation for dry, itching skin. ( Freitag, G; Höppner, T, 1997) |
| "Uremic pruritus is one of the most prevalent and bothersome dermatologic symptoms in patients with end-stage renal disease." | 6.66 | Gabapentin for uremic pruritus: a systematic review of randomized controlled trials. ( Castillo, RL; Dofitas, BL; Eusebio-Alpapara, KMV, 2020) |
| "Due to the actives urea, lactate, polidocanol, and the anti-inflammatory licochalcone A, the new scalp tonic exhibited excellent performance in alleviating scalp dryness, itching, microinflammation, and in normalizing disturbances of scalp lipids." | 5.17 | Efficacy of a new tonic containing urea, lactate, polidocanol, and glycyrrhiza inflata root extract in the treatment of a dry, itchy, and subclinically inflamed scalp. ( Baufeld, C; Drescher, P; Filbry, A; Höpfner, S; Lüttke, J; Max, H; Mess, A; Oltrogge, B; Rippke, F; Schweiger, D, 2013) |
| "In this pilot trial topical application of 10% Urea ISDIN ® plus dexpanthenol lotion has shown to improve skin dryness and pruritus in haemodialysis patients." | 5.15 | Efficacy of topical hydrating and emollient lotion containing 10% urea ISDIN® plus dexpanthenol (Ureadin Rx 10) in the treatment of skin xerosis and pruritus in hemodialyzed patients: an open prospective pilot trial. ( Castello, M; Milani, M, 2011) |
| "The analysis of the global estimation of severity of ichthyosis showed improvements being stronger in the body areas treated with Laceran 10% urea lotion (from 4." | 5.08 | Efficacy of urea therapy in children with ichthyosis. A multicenter randomized, placebo-controlled, double-blind, semilateral study. ( Bohnsack, K; Groll, S; Küster, W; Rippke, F; Traupe, H; Upmeyer, HJ, 1998) |
| "After 7 and 14 days of treatment, the tested urea-based cream resulted in a significant, progressive clinical improvement of xerosis and related pruritus in all patients." | 4.02 | 10% urea cream in senile xerosis: Clinical and instrumental evaluation. ( Dinotta, F; Lacarrubba, F; Micali, G; Verzì, AE, 2021) |
| "In an open multicentre drug monitoring survey, 1611 patients with atopic dermatitis, contact eczema, dry eczema, psoriasis and pruritus were treated with a preparation containing 5% urea and 3% polidocanol (laurylmacrogol)." | 3.69 | Results of a postmarketing drug monitoring survey with a polidocanol-urea preparation for dry, itching skin. ( Freitag, G; Höppner, T, 1997) |
| "Uremic pruritus is one of the most prevalent and bothersome dermatologic symptoms in patients with end-stage renal disease." | 2.66 | Gabapentin for uremic pruritus: a systematic review of randomized controlled trials. ( Castillo, RL; Dofitas, BL; Eusebio-Alpapara, KMV, 2020) |
| "Chronic pruritus is a common problem in patients with inflammatory skin diseases as well as in subjects with dry or sensitive skin." | 2.53 | Itch Management: Topical Agents. ( Metz, M; Staubach, P, 2016) |
| "The uremic pruritus is a very painful symptom suffered by chronic haemodialysis patients and is observed in 22 to 74% of the subjects." | 2.45 | [Pruritus and dryness of the skin in chronic kidney insufficiency and dialysis patients - a review]. ( Durrant-Finn, U; Mügge, C; Nenoff, P; Osten, B, 2009) |
| "The causes of chronic renal failure in Sudan and Sweden are also studied for comparison." | 1.27 | Chronic renal failure in Khartoum, Sudan. ( Abboud, OI; Danielson, BG; Osman, EM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (33.33) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 3 (12.50) | 29.6817 |
| 2010's | 4 (16.67) | 24.3611 |
| 2020's | 5 (20.83) | 2.80 |
| Authors | Studies |
|---|---|
| Mohajeranirad, M | 1 |
| Saeidi, N | 1 |
| Kamali Nejad, M | 1 |
| Almasi-Hashiani, A | 1 |
| Salehi, M | 1 |
| Latifi, SA | 1 |
| Spigariolo, CB | 1 |
| Ferrucci, SM | 1 |
| Eusebio-Alpapara, KMV | 1 |
| Castillo, RL | 1 |
| Dofitas, BL | 1 |
| Ding, H | 1 |
| Kiguchi, N | 1 |
| Perrey, DA | 1 |
| Nguyen, T | 1 |
| Czoty, PW | 1 |
| Hsu, FC | 1 |
| Zhang, Y | 1 |
| Ko, MC | 1 |
| Lacarrubba, F | 1 |
| Verzì, AE | 1 |
| Dinotta, F | 1 |
| Micali, G | 1 |
| Schweiger, D | 1 |
| Baufeld, C | 1 |
| Drescher, P | 1 |
| Oltrogge, B | 1 |
| Höpfner, S | 1 |
| Mess, A | 1 |
| Lüttke, J | 1 |
| Rippke, F | 2 |
| Filbry, A | 1 |
| Max, H | 1 |
| Gibson, RA | 1 |
| Robertson, J | 1 |
| Mistry, H | 1 |
| McCallum, S | 1 |
| Fernando, D | 1 |
| Wyres, M | 1 |
| Yosipovitch, G | 1 |
| Metz, M | 1 |
| Staubach, P | 1 |
| Durrant-Finn, U | 1 |
| Osten, B | 1 |
| Mügge, C | 1 |
| Nenoff, P | 1 |
| Castello, M | 1 |
| Milani, M | 1 |
| ROSENTHAL, D | 1 |
| BURNHAM, TK | 1 |
| Bowling, J | 1 |
| Cork, MJ | 1 |
| Abels, C | 1 |
| Proksch, E | 1 |
| Hiroshige, K | 1 |
| Kabashima, N | 1 |
| Takasugi, M | 1 |
| Kuroiwa, A | 1 |
| Freitag, G | 1 |
| Höppner, T | 1 |
| Küster, W | 1 |
| Bohnsack, K | 1 |
| Upmeyer, HJ | 1 |
| Groll, S | 1 |
| Traupe, H | 1 |
| Stüttgen, G | 1 |
| Osman, EM | 1 |
| Abboud, OI | 1 |
| Danielson, BG | 1 |
| Swanbeck, G | 1 |
| Rajka, G | 1 |
| Altchek, A | 1 |
| Dobbelstein, H | 1 |
| Schöffling, K | 1 |
| Petzoldt, R | 1 |
| Althoff-Zucker, C | 1 |
| Beyer, J | 1 |
| Retiene, K | 1 |
| Böhle, E | 1 |
| Kunkel, W | 1 |
| Ashton, H | 1 |
| Frenk, E | 1 |
| Stevenson, CJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Two Part Randomized, Double-blind, Placebo Controlled Study to Investigate the Effects of Topical Doses of SB705498 Oncapsaicin, Histamine, and Cowhage Responses in Healthy Volunteers.[NCT01673529] | Phase 1 | 16 participants (Actual) | Interventional | 2012-07-17 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for urea and Itching
| Article | Year |
|---|---|
Gabapentin for uremic pruritus: a systematic review of randomized controlled trials.
Topics: Dizziness; Gabapentin; Humans; Incidence; Kidney Failure, Chronic; Pruritus; Randomized Controlled T | 2020 |
Itch Management: Topical Agents.
Topics: Administration, Cutaneous; Analgesics, Opioid; Anesthetics, Local; Antipruritics; Camphor; Cannabino | 2016 |
[Pruritus and dryness of the skin in chronic kidney insufficiency and dialysis patients - a review].
Topics: Antipruritics; Arginine; Calcineurin Inhibitors; Capsaicin; Controlled Clinical Trials as Topic; Hum | 2009 |
Liver-kidney interrelation in pregnancy and toxemia.
Topics: Acute Kidney Injury; Ammonia; Erythrocytes; Estrogens; Female; Glomerular Filtration Rate; Glucocort | 1968 |
[Pathogenesis of uremia].
Topics: Acidosis; Aminobenzoates; Ammonia; Anemia; Animals; Butyrates; Cardiovascular Diseases; Central Nerv | 1971 |
7 trials available for urea and Itching
| Article | Year |
|---|---|
Effects of
Topics: Aged; Albumins; Anorexia; Creatinine; Dietary Supplements; Double-Blind Method; Fatigue; Helichrysum | 2021 |
Efficacy of a new tonic containing urea, lactate, polidocanol, and glycyrrhiza inflata root extract in the treatment of a dry, itchy, and subclinically inflamed scalp.
Topics: Chalcones; Cytokines; Glycyrrhiza; Humans; Lactic Acid; Lipid Metabolism; Plant Extracts; Plant Root | 2013 |
A randomised trial evaluating the effects of the TRPV1 antagonist SB705498 on pruritus induced by histamine, and cowhage challenge in healthy volunteers.
Topics: Administration, Topical; Adult; Capsaicin; Healthy Volunteers; Histamine; Humans; Male; Middle Aged; | 2014 |
Efficacy of topical hydrating and emollient lotion containing 10% urea ISDIN® plus dexpanthenol (Ureadin Rx 10) in the treatment of skin xerosis and pruritus in hemodialyzed patients: an open prospective pilot trial.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Emollients; Female; Humans; Kidney Failure, | 2011 |
Optimal dialysis improves uremic pruritus.
Topics: beta 2-Microglobulin; Blood Urea Nitrogen; Female; Humans; Male; Middle Aged; Nutritional Status; Pr | 1995 |
Efficacy of urea therapy in children with ichthyosis. A multicenter randomized, placebo-controlled, double-blind, semilateral study.
Topics: Adolescent; Child; Child, Preschool; Dermatitis, Contact; Dermatitis, Irritant; Double-Blind Method; | 1998 |
Antipruritic effect of urea solutions. An experimental and clinical study.
Topics: Adult; Aged; Clinical Trials as Topic; Dermatologic Agents; Female; Humans; Male; Middle Aged; Place | 1970 |
12 other studies available for urea and Itching
| Article | Year |
|---|---|
Efficacy and tolerability of a repairing moisturizing cream containing amino-inositole and urea 10% in adults with chronic eczematous dermatitis of the hands.
Topics: Adult; Eczema; Emollients; Humans; Immunoglobulin A; Pain; Pruritus; Treatment Outcome; Urea | 2023 |
Antinociceptive, reinforcing, and pruritic effects of the G-protein signalling-biased mu opioid receptor agonist PZM21 in non-human primates.
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Pruritus; Recep | 2020 |
10% urea cream in senile xerosis: Clinical and instrumental evaluation.
Topics: Aged; Eczema; Emollients; Humans; Pruritus; Treatment Outcome; Urea | 2021 |
NONTHROMBOCYTOPENIC PURPURA DUE TO CARBROMAL INGESTION.
Topics: Antigen-Antibody Reactions; Drug Eruptions; Humans; Hypnotics and Sedatives; IgA Vasculitis; Leg Der | 1964 |
Severe pruritus in a patient with urticaria pigmentosa treated with topical 5% urea and 3% polidocanol cream.
Topics: Administration, Topical; Detergents; Humans; Male; Middle Aged; Polidocanol; Polyethylene Glycols; P | 2003 |
[Therapy of atopic dermatitis].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Calcineurin Inhibitors; Child; Combined Modality Therap | 2006 |
Results of a postmarketing drug monitoring survey with a polidocanol-urea preparation for dry, itching skin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child, Preschool; Dermatitis, Atopic; Drug Combinations; | 1997 |
[Results and consequences of long-term urea therapy for clinical practice].
Topics: Administration, Topical; Anti-Inflammatory Agents; Dermatitis, Atopic; Drug Combinations; Humans; Hy | 1992 |
Chronic renal failure in Khartoum, Sudan.
Topics: Adolescent; Adult; Aged; Creatinine; Epistaxis; Female; Humans; Hypertension, Renal; Kidney Failure, | 1987 |
Urea for treatment of dry skin.
Topics: Administration, Topical; Costs and Cost Analysis; Drug Evaluation; Humans; Ichthyosis; Pruritus; Ski | 1973 |
[Clinical experiences with oral antidiabetic HB 419 (glibenclamide)].
Topics: Alanine Transaminase; Alkaline Phosphatase; Blood Cell Count; Blood Glucose; Blood Platelets; Body W | 1969 |
Therapeutics 13. Urea as a topical agent.
Topics: Animals; Humans; Ichthyosis; Protein Denaturation; Pruritus; Skin; Solvents; Urea; Wound Infection | 1971 |