urea has been researched along with Ichthyosis in 40 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Ichthyosis: Any of several generalized skin disorders characterized by dryness, roughness, and scaliness, due to hypertrophy of the stratum corneum epidermis. Most are genetic, but some are acquired, developing in association with other systemic disease or genetic syndrome.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Optimization of a topical formula of N-acetylcysteine and urea for the topical treatment of ichthyosis." | 9.22 | Development of a carbocysteine 10% + urea 5% cream for the topical treatment of congenital ichthyosis. ( Batalla-Cebey, A; Crespo-Diz, C; Dávila-Pousa, MC; González-Freire, L, 2022) |
| "The analysis of the global estimation of severity of ichthyosis showed improvements being stronger in the body areas treated with Laceran 10% urea lotion (from 4." | 9.08 | Efficacy of urea therapy in children with ichthyosis. A multicenter randomized, placebo-controlled, double-blind, semilateral study. ( Bohnsack, K; Groll, S; Küster, W; Rippke, F; Traupe, H; Upmeyer, HJ, 1998) |
| "N-acetylcysteine in combination with urea is effective for the treatment of congenital ichthyosis." | 7.88 | Topical carbocysteine: A new option for the treatment of ichthyosis. ( Batalla, A; Dávila-Pousa, C; Feal, C; Flórez, Á, 2018) |
| "Optimization of a topical formula of N-acetylcysteine and urea for the topical treatment of ichthyosis." | 5.22 | Development of a carbocysteine 10% + urea 5% cream for the topical treatment of congenital ichthyosis. ( Batalla-Cebey, A; Crespo-Diz, C; Dávila-Pousa, MC; González-Freire, L, 2022) |
| "The analysis of the global estimation of severity of ichthyosis showed improvements being stronger in the body areas treated with Laceran 10% urea lotion (from 4." | 5.08 | Efficacy of urea therapy in children with ichthyosis. A multicenter randomized, placebo-controlled, double-blind, semilateral study. ( Bohnsack, K; Groll, S; Küster, W; Rippke, F; Traupe, H; Upmeyer, HJ, 1998) |
| "N-acetylcysteine in combination with urea is effective for the treatment of congenital ichthyosis." | 3.88 | Topical carbocysteine: A new option for the treatment of ichthyosis. ( Batalla, A; Dávila-Pousa, C; Feal, C; Flórez, Á, 2018) |
| "Preparations containing urea were found to be effective in the treatment of ichthyosis vulgaris and so we were encouraged to test their use in other dry skin conditions." | 3.67 | [Urea as a single drug in dry skin]. ( Swanbeck, G, 1989) |
| "The uremic pruritus is a very painful symptom suffered by chronic haemodialysis patients and is observed in 22 to 74% of the subjects." | 2.45 | [Pruritus and dryness of the skin in chronic kidney insufficiency and dialysis patients - a review]. ( Durrant-Finn, U; Mügge, C; Nenoff, P; Osten, B, 2009) |
| "Urea is a major component of many daily skincare products which is widely used." | 1.56 | Mode of action of urea. ( Dirschka, T, 2020) |
| "Urea has anti-inflammatory, hyposensitizing, and antioxidant effect." | 1.36 | [The evaluation of nitrogen metabolism and the reactivity of the organism in patients with dry skin]. ( Katsitadze, AG; Tsiskarishvili, NI; Tsiskarishvili, NV, 2010) |
| "Salicylic acid ointment was applied on one and carbamide ointment on the other back of the hand." | 1.28 | [Water content of the skin following salicylic acid and urea treatment]. ( Jakab, E; Rácz, I; Soós, G, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (67.50) | 18.7374 |
| 1990's | 1 (2.50) | 18.2507 |
| 2000's | 4 (10.00) | 29.6817 |
| 2010's | 5 (12.50) | 24.3611 |
| 2020's | 3 (7.50) | 2.80 |
| Authors | Studies |
|---|---|
| González-Freire, L | 1 |
| Dávila-Pousa, MC | 1 |
| Batalla-Cebey, A | 1 |
| Crespo-Diz, C | 1 |
| Verzì, AE | 1 |
| Musumeci, ML | 1 |
| Lacarrubba, F | 1 |
| Micali, G | 1 |
| Dirschka, T | 1 |
| Batalla, A | 1 |
| Dávila-Pousa, C | 1 |
| Feal, C | 1 |
| Flórez, Á | 1 |
| Lindh, JD | 1 |
| Bradley, M | 1 |
| Danby, SG | 1 |
| Brown, K | 1 |
| Higgs-Bayliss, T | 1 |
| Chittock, J | 1 |
| Albenali, L | 1 |
| Cork, MJ | 1 |
| Faergemann, J | 1 |
| Olsson, P | 1 |
| Svensson, A | 1 |
| Durrant-Finn, U | 1 |
| Osten, B | 1 |
| Mügge, C | 1 |
| Nenoff, P | 2 |
| Tsiskarishvili, NV | 1 |
| Katsitadze, AG | 1 |
| Tsiskarishvili, NI | 1 |
| Machan, M | 1 |
| Kestenbaum, T | 1 |
| Fraga, GR | 1 |
| Donaubauer, K | 1 |
| Arndt, T | 1 |
| Haustein, UF | 1 |
| Gilardi, S | 1 |
| Schibli, H | 1 |
| Grekin, JL | 1 |
| Basler, RS | 1 |
| Küster, W | 1 |
| Bohnsack, K | 1 |
| Rippke, F | 1 |
| Upmeyer, HJ | 1 |
| Groll, S | 1 |
| Traupe, H | 1 |
| Ademola, J | 1 |
| Frazier, C | 1 |
| Kim, SJ | 1 |
| Theaux, C | 1 |
| Saudez, X | 1 |
| Fisher, AA | 1 |
| Blair, C | 1 |
| Horii, I | 1 |
| Nakayama, Y | 1 |
| Obata, M | 1 |
| Tagami, H | 1 |
| Schnyder, UW | 1 |
| Swanbeck, G | 3 |
| Rácz, I | 1 |
| Soós, G | 1 |
| Jakab, E | 1 |
| Wohlrab, W | 1 |
| Taube, KM | 1 |
| Vol'rab, V | 1 |
| Vozniak, KD | 1 |
| Beverley, DW | 1 |
| Wheeler, D | 1 |
| Garty, BZ | 1 |
| Grice, K | 1 |
| Sattar, H | 1 |
| Baker, H | 1 |
| Zuehlke, RL | 1 |
| Pope, FM | 1 |
| Rees, JK | 1 |
| Wells, RS | 1 |
| Lewis, KG | 1 |
| Jacoby, RH | 1 |
| Gilkes, JJ | 1 |
| Almeyda, J | 1 |
| Fry, L | 1 |
| Hindson, TC | 1 |
| Nash, DP | 1 |
| Solente, G | 1 |
| Ashton, H | 1 |
| Frenk, E | 1 |
| Stevenson, CJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Skin Pathology Assessment With Optical Technologies (SPOT): a Cross- Sectional Clinical Study in Atopic Dermatitis Patients and Healthy Subjects[NCT04295824] | 80 participants (Anticipated) | Observational | 2020-08-06 | Recruiting | |||
| Validation of a Novel Composite of Skin Biomarkers as a Primary Outcome Measure for Evaluating the Safety of Treatments for Atopic Dermatitis: a Randomized Controlled Trial (Phase 2) Comparing the Effects of Crisaborole 2% Ointment to Betamethasone Valera[NCT04194814] | Phase 2 | 37 participants (Actual) | Interventional | 2020-11-20 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for urea and Ichthyosis
| Article | Year |
|---|---|
Development of a carbocysteine 10% + urea 5% cream for the topical treatment of congenital ichthyosis.
Topics: Administration, Topical; Carbocysteine; Humans; Ichthyosis; Ichthyosis, Lamellar; Urea | 2022 |
Clinical Effectiveness of Moisturizers in Atopic Dermatitis and Related Disorders: A Systematic Review.
Topics: Dermatitis, Atopic; Dermatitis, Irritant; Emollients; Epidermis; Glycerol; Hand Dermatoses; Humans; | 2015 |
[Pruritus and dryness of the skin in chronic kidney insufficiency and dialysis patients - a review].
Topics: Antipruritics; Arginine; Calcineurin Inhibitors; Capsaicin; Controlled Clinical Trials as Topic; Hum | 2009 |
[Urea and urea combinations in ichthyoses].
Topics: Administration, Topical; Dermatologic Agents; Drug Therapy, Combination; Humans; Ichthyosis; Urea | 1989 |
[Therapy of "dry skin" with creams containing urea].
Topics: Humans; Ichthyosis; Ointments; Skin; Urea; Water-Electrolyte Balance | 1988 |
10 trials available for urea and Ichthyosis
| Article | Year |
|---|---|
A randomized, single-blind comparison of the efficacy, tolerability and cosmetic acceptance of Propyless or Fenuril treatment of patients with dry skin.
Topics: Administration, Topical; Adult; Aged; Emollients; Esthetics; Female; Humans; Ichthyosis; Leg; Male; | 2009 |
[Topically applied arginine hydrochloride. Effect on urea content of stratum corneum and skin hydration in atopic eczema and skin aging].
Topics: Administration, Topical; Adult; Aged; Arginine; Biopsy; Dermatitis, Atopic; Epidermis; Female; Human | 2004 |
Efficacy of urea therapy in children with ichthyosis. A multicenter randomized, placebo-controlled, double-blind, semilateral study.
Topics: Adolescent; Child; Child, Preschool; Dermatitis, Contact; Dermatitis, Irritant; Double-Blind Method; | 1998 |
Clinical evaluation of 40% urea and 12% ammonium lactate in the treatment of xerosis.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Double-Blind Method; Drug Administration Schedul | 2002 |
The action of a urea-lactic acid ointment in ichthyosis with particular reference to the thickness of the horny layer.
Topics: Adolescent; Adult; Aged; Female; Humans; Ichthyosis; Lactates; Male; Middle Aged; Ointment Bases; Ps | 1976 |
Urea and retinoic acid in ichthyosis and their effect on transepidermal water loss and water holding capacity of stratum corneum.
Topics: Adolescent; Adult; Child; Chromosome Aberrations; Chromosome Disorders; Female; Humans; Ichthyosis; | 1973 |
Out-patient treatment of ichthyosis: a double-blind trial of ointments.
Topics: Attitude to Health; Clinical Trials as Topic; Dermatologic Agents; Emulsions; Humans; Ichthyosis; Oi | 1972 |
Carbamide in hyperkeratosis.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Dermatitis, Atopic; Eval | 1973 |
A new urea/hydrocortisone powder-cream compared with other topical corticosteroid preparations: a six-centre study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Betamethasone; Child; Ch | 1974 |
Controlled trial of the treatment of atopic eczema with a urea-hydrocortisone preparation versus betamethasone 17-valerat.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Betamethasone; Child; Ch | 1973 |
25 other studies available for urea and Ichthyosis
| Article | Year |
|---|---|
History of urea as a dermatological agent in clinical practice.
Topics: Dermatitis, Atopic; Dermatologic Agents; Eczema; Humans; Ichthyosis; Urea | 2020 |
Mode of action of urea.
Topics: Dermatitis, Atopic; Humans; Ichthyosis; Psoriasis; Skin; Urea | 2020 |
Topical carbocysteine: A new option for the treatment of ichthyosis.
Topics: Administration, Topical; Anti-Infective Agents, Local; Carbocysteine; Child; Child, Preschool; Drug | 2018 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
The Effect of an Emollient Containing Urea, Ceramide NP, and Lactate on Skin Barrier Structure and Function in Older People with Dry Skin.
Topics: Aged; Aged, 80 and over; Ceramides; Cohort Studies; Emollients; Epidermis; Female; Humans; Ichthyosi | 2016 |
[The evaluation of nitrogen metabolism and the reactivity of the organism in patients with dry skin].
Topics: Adolescent; Adult; Dermatitis, Atopic; Desiccation; Filaggrin Proteins; Humans; Ichthyosis; Immunogl | 2010 |
Diffuse hyperkeratosis in a deaf and blind 48-year-old woman--quiz case. Diagnosis: keratitis-ichthyosis-deafness (KID) syndrome with secondary dermatophytosis.
Topics: Antifungal Agents; Baths; Blindness; Deafness; Dermatologic Agents; Female; Fluconazole; Humans; Ich | 2012 |
[Therapeutic possibilities in ichthyosis and ichthyosiforme states].
Topics: Adolescent; Child; Child, Preschool; Etretinate; Female; Humans; Ichthyosis; Male; Urea | 1982 |
New treatments for ichthyosis.
Topics: Humans; Hydroxy Acids; Ichthyosis; Petrolatum; Propylene Glycols; Salicylates; Skin; Urea; Vitamin A | 1980 |
Irritant reactions from topical urea preparations used for dry skin. Advantages of a urea-free "Dead Sea salt" cream.
Topics: Administration, Topical; Drug Eruptions; Humans; Ichthyosis; Ointments; Patch Tests; Skin Diseases; | 1976 |
Stratum corneum hydration and amino acid content in xerotic skin.
Topics: Aged; Aged, 80 and over; Amino Acids; Body Water; Epidermis; Galvanic Skin Response; Humans; Ichthyo | 1989 |
[Urea as a single drug in dry skin].
Topics: Administration, Topical; Dermatologic Agents; Drug Therapy, Combination; Eczema; Hand Dermatoses; Hu | 1989 |
[Water content of the skin following salicylic acid and urea treatment].
Topics: Administration, Topical; Adult; Body Water; Dermatologic Agents; Female; Hand Dermatoses; Humans; Ic | 1989 |
[Use of a urea emulsion in the treatment of dry skin].
Topics: Administration, Topical; Emulsions; Humans; Ichthyosis; Urea | 1986 |
High plasma urea concentrations in collodion babies.
Topics: Betaine; Drug Combinations; Female; Humans; Ichthyosis; Infant, Newborn; Lactates; Lactic Acid; Skin | 1986 |
High plasma urea concentration in babies with lamellar ichthyosis.
Topics: Drug Combinations; Humans; Ichthyosis; Infant; Infant, Newborn; Lactates; Lactic Acid; Skin Absorpti | 1986 |
High plasma urea concentrations in collodion babies.
Topics: Dermatologic Agents; Humans; Ichthyosis; Infant, Newborn; Urea | 1987 |
A new treatment of ichthyosis and other hyperkeratotic conditions.
Topics: Adolescent; Adult; Aged; Eczema; Female; Humans; Humidity; Ichthyosis; Male; Ointments; Psoriasis; S | 1968 |
Recent therapeutic advances for common cutaneous problems.
Topics: Acne Vulgaris; Administration, Topical; Coloring Agents; Cytarabine; Dermatologic Agents; Ethyl Ethe | 1974 |
Urea for treatment of dry skin.
Topics: Administration, Topical; Costs and Cost Analysis; Drug Evaluation; Humans; Ichthyosis; Pruritus; Ski | 1973 |
Urea in the topical treatment of atopic eczema.
Topics: Adult; Betamethasone; Child; Child, Preschool; Chronic Disease; Dermatologic Agents; Eczema; Foot De | 1971 |
Urea cream for dry skin.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Ichthyosis; Male; Middle Aged; Ointments; Skin; Urea | 1971 |
[An unknowed keratolytic agent: urea].
Topics: Aspirin; Dermatologic Agents; Drug Combinations; Humans; Ichthyosis; Lanolin; Psoriasis; Urea | 1971 |
Therapeutics 13. Urea as a topical agent.
Topics: Animals; Humans; Ichthyosis; Protein Denaturation; Pruritus; Skin; Solvents; Urea; Wound Infection | 1971 |
Calmurid: a urea cream for the skin.
Topics: Humans; Ichthyosis; Keratosis; Ointments; Urea | 1971 |
[Carbamide cream for dry and hyperkeratotic skin].
Topics: Dermatologic Agents; Humans; Ichthyosis; Ointments; Prurigo; Urea | 1968 |