Page last updated: 2024-10-20

urea and Hyponatremia

urea has been researched along with Hyponatremia in 133 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Hyponatremia: Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"The clinical trial confirmed the better palatability of the commercial oral urea formulation, containing citrus flavor, which therefore represents a therapeutic strategy that could improve adherence to the therapy in chronic patients with hyponatremia."9.69Palatability of two different formulations of urea for the treatment of hyponatremia: A double-blind, randomized, cross-over study. ( Colombo, F; Milani, M, 2023)
"These preliminary data show that urea appears to be an effective therapeutic approach for the polydipsiahyponatremia syndrome."9.11Treatment of the polydipsia-hyponatremia syndrome with urea. ( Decaux, G; Musch, W; Verhoeven, A, 2005)
"Small case series conducted in Europe since the early 1980s suggest that urea, an oral osmotic diuretic that increases urinary water excretion, is safe and effective for the treatment of chronic hyponatremia."9.05Urea for Chronic Hyponatremia. ( Rondon-Berrios, H, 2020)
" Following failed attempts to correct hyponatremia with fluid restriction and other therapeutics, urea normalized sodium levels and allowed liberalization of formula volumes, which resulted in improved weight gain."8.31Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1. ( Cui, J; Halpin, K; Paprocki, E, 2023)
"We retrospectively analysed 36 cancer patients affected by moderate or profound SIAD-induced chronic hyponatremia, who started oral urea (initial daily dose 15 g or 30 g) without fluid restriction between July 2013 and July 2018."7.91Urea in cancer patients with chronic SIAD-induced hyponatremia: Old drug, new evidence. ( Arvat, E; Castellana, E; Cattel, F; D'Angelo, V; Grossi, E; Nervo, A; Rosso, D, 2019)
"In our Department, enteral urea is routinely administered to patients with acute brain injury who develop hyponatremia consistent with SIADH and do not respond to an initial sodium load."7.85Early Effects of Enteral Urea on Intracranial Pressure in Patients With Acute Brain Injury and Hyponatremia. ( Annoni, F; Brimioulle, S; Creteur, J; Fontana, V; Taccone, FS; Vincent, JL, 2017)
"Once the standard of care for cerebral edema, urea can also be used to treat hyponatremia."7.81Urea for hyponatremia? ( Hix, JK; Silver, SM; Sterns, RH, 2015)
" The first one is represented by a retrospective study of 50 consecutive patients with mild hyponatremia treated with urea."7.76Treatment of euvolemic hyponatremia in the intensive care unit by urea. ( Andres, C; Decaux, G; Gankam Kengne, F; Soupart, A, 2010)
"We report the successful use of oral urea in the management of children with chronic syndrome of inappropriate antidiuretic hormone secretion (SIAD)."7.73Oral urea for the treatment of chronic syndrome of inappropriate antidiuresis in children. ( Feldman, BJ; Geller, DH; Gitelman, SE; Huang, EA; Rosenthal, SM; Schwartz, ID, 2006)
"It was recently demonstrated that renal failure and exogenous urea prevent myelinolysis induced by rapid correction of experimental hyponatremia."7.71Rapid (24-hour) reaccumulation of brain organic osmolytes (particularly myo-inositol) in azotemic rats after correction of chronic hyponatremia. ( Decaux, G; Schroöeder, B; Silver, S; Soupart, A; Sterns, R, 2002)
"We analyzed the serum anion gap (AG = sodium plus potassium minus chloride plus bicarbonate, N = 11-21 mEq/l), serum uric acid and urea concentrations in hyponatremia of various origins."7.69Uric acid, anion gap and urea concentration in the diagnostic approach to hyponatremia. ( Brimioulle, S; Coffernils, M; Decaux, G; Namias, B; Prospert, F; Schlesser, M; Soupart, A, 1994)
"We have studied the efficiency of urea in the treatment of hyponatremia and hydrosaline retention in a 76-year-old man with chronic ischemic congestive heart failure."7.67Urea treatment for water retention in hyponatremic congestive heart failure. ( Cauchie, P; Decaux, G; Vincken, W, 1987)
"We have studied the efficacy of urea in the treatment of hyponatremia and hydrosaline retention in cirrhotic patients with ascites resistant to diuretics."7.67Treatment of hyponatremic cirrhosis with ascites resistant to diuretics by urea. ( Cauchie, P; Decaux, G; Delwiche, F; Flamion, B; Mols, P, 1986)
"Hyponatremia is a common electrolyte disorder that carries significant morbidity and mortality."5.42Urea minimizes brain complications following rapid correction of chronic hyponatremia compared with vasopressin antagonist or hypertonic saline. ( Couturier, BS; Decaux, G; Gankam Kengne, F; Soupart, A, 2015)
"Myoinositol-treated animals had significantly fewer demyelinating lesions than mannitol (2."5.33Myoinositol administration improves survival and reduces myelinolysis after rapid correction of chronic hyponatremia in rats. ( Rojiani, AM; Schroeder, BM; Silver, SM; Sterns, RH, 2006)
"Reported successes in the treatment of hyponatremia due to SIADH by administration of urea and normal saline led to the authors' routine use of this therapy for hyponatremic neurosurgical patients."5.28Administration of intravenous urea and normal saline for the treatment of hyponatremia in neurosurgical patients. ( Harbaugh, RE; Reeder, RF, 1989)
" Urea and vaptans can be effective treatments for the syndrome of inappropriate antidiuresis and hyponatremia in patients with heart failure, but have adverse effects (eg, poor palatability and gastric intolerance with urea; and overly rapid correction of hyponatremia and increased thirst with vaptans)."5.22Diagnosis and Management of Hyponatremia: A Review. ( Adrogué, HJ; Madias, NE; Tucker, BM, 2022)
"These preliminary data show that urea appears to be an effective therapeutic approach for the polydipsiahyponatremia syndrome."5.11Treatment of the polydipsia-hyponatremia syndrome with urea. ( Decaux, G; Musch, W; Verhoeven, A, 2005)
"Small case series conducted in Europe since the early 1980s suggest that urea, an oral osmotic diuretic that increases urinary water excretion, is safe and effective for the treatment of chronic hyponatremia."5.05Urea for Chronic Hyponatremia. ( Rondon-Berrios, H, 2020)
"Urea has been recently proposed for the management of hyponatremia linked to the syndrome of inappropriate secretion of ADH (SIADH)."4.90Urea for management of the syndrome of inappropriate secretion of ADH: A systematic review. ( de Solà-Morales, O; Riera, M, 2014)
"Approaches, such as vasopressin receptor antagonists or urea, have been shown to reverse moderate hyponatremia."4.89Hyponatremia: an update on current pharmacotherapy. ( Schrier, RW; Shchekochikhin, D; Tkachenko, O, 2013)
"Malignancy; liver cirrhosis; dialysis treatment; increased Charlson comorbidity index, urea, and C-reactive protein values and the use of antineoplastic drugs are associated with mortality."4.31Risk factors and mortality in elderly patients with severe hyponatremia admitted to the emergency department. ( Bozkurt Babuş, S; Erdoğan, S; İyikesici, F; Kiraz, M; Köse, A, 2023)
" Following failed attempts to correct hyponatremia with fluid restriction and other therapeutics, urea normalized sodium levels and allowed liberalization of formula volumes, which resulted in improved weight gain."4.31Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1. ( Cui, J; Halpin, K; Paprocki, E, 2023)
" Anorexia and the combination of thiazide together with furosemide, rather than thiazide use alone, were risk factors for hypovolemic hyponatremia without affecting FE-UA."4.12Thiazide-associated hyponatremia in internal medicine patients: analysis of epidemiological and biochemical profiles. ( Klhůfek, J; Šálek, T, 2022)
" The risk factors at admission associated with CE development were high serum urea levels, hyponatremia, and hypocapnia."3.96Prevalence of cerebral edema among diabetic ketoacidosis patients. ( Balboa, R; Ferraro, M; González Pannia, P; Mannucci, C; Navarro, R; Nocita, MF, 2020)
"We retrospectively analysed 36 cancer patients affected by moderate or profound SIAD-induced chronic hyponatremia, who started oral urea (initial daily dose 15 g or 30 g) without fluid restriction between July 2013 and July 2018."3.91Urea in cancer patients with chronic SIAD-induced hyponatremia: Old drug, new evidence. ( Arvat, E; Castellana, E; Cattel, F; D'Angelo, V; Grossi, E; Nervo, A; Rosso, D, 2019)
"In our Department, enteral urea is routinely administered to patients with acute brain injury who develop hyponatremia consistent with SIADH and do not respond to an initial sodium load."3.85Early Effects of Enteral Urea on Intracranial Pressure in Patients With Acute Brain Injury and Hyponatremia. ( Annoni, F; Brimioulle, S; Creteur, J; Fontana, V; Taccone, FS; Vincent, JL, 2017)
"Urea administration appears useful for the treatment of SIADH-associated hyponatremia in critically ill patients."3.78Treatment of the syndrome of inappropriate secretion of antidiuretic hormone with urea in critically ill patients. ( Bankir, L; Biston, P; Coussement, J; Danguy, C; Defrance, P; Piagnerelli, M; Zouaoui-Boudjeltia, K, 2012)
"We report the successful use of oral urea in the management of children with chronic syndrome of inappropriate antidiuretic hormone secretion (SIAD)."3.73Oral urea for the treatment of chronic syndrome of inappropriate antidiuresis in children. ( Feldman, BJ; Geller, DH; Gitelman, SE; Huang, EA; Rosenthal, SM; Schwartz, ID, 2006)
"It was recently demonstrated that renal failure and exogenous urea prevent myelinolysis induced by rapid correction of experimental hyponatremia."3.71Rapid (24-hour) reaccumulation of brain organic osmolytes (particularly myo-inositol) in azotemic rats after correction of chronic hyponatremia. ( Decaux, G; Schroöeder, B; Silver, S; Soupart, A; Sterns, R, 2002)
"The high fractional excretion (FE) of uric acid observed in hyponatremia associated with the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is commonly attributed to the volume-expanded state, although volume expansion in normonatremic volunteers is unable to increase urate clearance to a degree similar to that in SIADH."3.70Evidence that chronicity of hyponatremia contributes to the high urate clearance observed in the syndrome of inappropriate antidiuretic hormone secretion. ( Decaux, G; Musch, W; Prospert, F; Soupart, A, 2000)
"We analyzed the serum anion gap (AG = sodium plus potassium minus chloride plus bicarbonate, N = 11-21 mEq/l), serum uric acid and urea concentrations in hyponatremia of various origins."3.69Uric acid, anion gap and urea concentration in the diagnostic approach to hyponatremia. ( Brimioulle, S; Coffernils, M; Decaux, G; Namias, B; Prospert, F; Schlesser, M; Soupart, A, 1994)
"The present study was designed to investigate in rats the influence of converting enzyme inhibition with captopril on blood pressure, plasma urea, plasma renin concentration (PRC), plasma aldosterone and plasma vasopressin, and to define the interrelationships between PRC and these variables during equal degrees of either hyponatraemic (furosemide, 40 mg/kg for 2 days) or hypernatraemic (48-h water deprivation) dehydration."3.67Influence of converting enzyme inhibition on the hormonal and renal adaptation to hyper- and hyponatraemic dehydration. ( Corvol, P; Gardes, J; Gonzalez, MF; Ménard, J, 1986)
"We have studied the efficiency of urea in the treatment of hyponatremia and hydrosaline retention in a 76-year-old man with chronic ischemic congestive heart failure."3.67Urea treatment for water retention in hyponatremic congestive heart failure. ( Cauchie, P; Decaux, G; Vincken, W, 1987)
"We have studied the efficacy of urea in the treatment of hyponatremia and hydrosaline retention in cirrhotic patients with ascites resistant to diuretics."3.67Treatment of hyponatremic cirrhosis with ascites resistant to diuretics by urea. ( Cauchie, P; Decaux, G; Delwiche, F; Flamion, B; Mols, P, 1986)
"Urea has efficacy similar to that of vaptans for treatment of chronic SIADH."2.77Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH. ( Coffernils, M; Couturier, B; Decaux, G; Gankam-Kengne, F; Soupart, A, 2012)
"The occurrence of renal failure is associated to an increased death risk."2.73Hypertonic saline solution for renal failure prevention in patients with decompensated heart failure. ( Azevedo, CH; Bacal, F; Bocchi, EA; Carneiro, RM; Chizzola, PR; Ferreira, SM; Issa, VS; Mangini, S, 2007)
"The rationale for treating the hyponatremia, even when apparently asymptomatic, is discussed, with attention to cognitive function, gait, and bone structure disturbances that increase the risk for fractures."2.49An elderly patient with chronic hyponatremia. ( Berl, T, 2013)
" In short and long term studies, tolvaptane has been shown to be effective in raising serum sodium levels in a predictable fashion in patients with SIADH with only few side effects, when serum sodium was frequently monitored and dosage of tolvaptans was properly adjusted."2.47[Treatment of hyponatremia: new developments and controversies]. ( Hensen, J, 2011)
"Inadequate treatment of severe hyponatremia (<120 mEq/L) can be associated with severe neurological damage."2.42Treatment of symptomatic hyponatremia. ( Decaux, G; Soupart, A, 2003)
"Inadequate treatment of severe hyponatremia (< 120 mEq/l) can be associated with severe neurological damage."2.41[Treatment of severe hyponatremia (<120mEq/l)]. ( Decaux, G, 2001)
" The osmole gap may also be helpful for confirming pseudohyponatremia, as a gauge for dosing mannitol and glycerol when used to treat intracranial hypertension, and as a prognostic indicator in circulatory shock."2.39The serum osmole gap. ( Cadnapaphornchai, P; Kruse, JA, 1994)
"Future research into the treatment of SIADH must be directed at developing effective antagonists of ADH."2.37Management of the syndrome of inappropriate secretion of antidiuretic hormone. ( Kinzie, BJ, 1987)
"Hyponatremia is a state of an osmole-free water excess compared to the amounts of solutes and clinical management of hyponatremic patients requires pathophysiology-oriented approaches to select appropriate treatments."1.62[Hyponatremia - causes, diagnostic evaluation and treatment]. ( Kettritz, R, 2021)
"In hospitalised patients with a serum sodium level ≤ 129 mmol/l due to SIADH, urea in a dosage of 0."1.56Urea for hyponatraemia due to the syndrome of inappropriate antidiuretic hormone secretion. ( de Boer, MP; Hempenius, L; van Roon, EN; Woudstra, J, 2020)
"This hyponatremia is saline-responsive, but relapse can be frequently observed."1.51Hyponatremia secondary to transient renal salt wasting (TRSW): A not so uncommon observation in the elderly
. ( Decaux, G; Musch, W, 2019)
"Urea was used on 78 occasions in 69 patients."1.51Urea treatment in fluid restriction-refractory hyponatraemia. ( Berkman, KE; Dimeski, G; Inder, WJ; Lockett, J; Russell, AW, 2019)
"Oral urea was utilized in 5 SIADH patients where Na failed to increase with fluid restriction alone."1.48Investigation and management of moderate to severe inpatient hyponatraemia in an Australian tertiary hospital. ( Berkman, K; Dimeski, G; Haigh, K; Inder, WJ; Li, L; Lockett, J; Russell, A, 2018)
"We report the approach to the treatment of hyponatremia and its unique challenges in infancy."1.42Approach to the treatment of the infant with hyponatremia. ( Greenberg, JH; Marsenic, O; Tufro, A, 2015)
"Hyponatremia is a common electrolyte disorder that carries significant morbidity and mortality."1.42Urea minimizes brain complications following rapid correction of chronic hyponatremia compared with vasopressin antagonist or hypertonic saline. ( Couturier, BS; Decaux, G; Gankam Kengne, F; Soupart, A, 2015)
"Hyponatremia is the main complication of inappropriate antidiuretic hormone secretion (SIADH), sometimes fatal."1.38Inappropriate antidiuretic hormone secretion: long-term successful urea treatment. ( Cachat, F; Chehade, H; Girardin, E; Rosato, L, 2012)
"Hyponatremia was induced in male Sprague-Dawley rats by water loading and subcutaneous infusion of 1-deamino-8-D-arginine vasopressin (dDAVP)."1.33BSC1 inhibition complements effects of vasopressin V2 receptor antagonist on hyponatremia in SIADH rats. ( Arata, T; Ejima, Y; Hatano, R; Kazama, I; Matsubara, M; Michimata, M; Miyama, N; Sasaki, S; Sato, A; Satomi, S; Suzuki, K; Suzuki, M, 2005)
"Myoinositol-treated animals had significantly fewer demyelinating lesions than mannitol (2."1.33Myoinositol administration improves survival and reduces myelinolysis after rapid correction of chronic hyponatremia in rats. ( Rojiani, AM; Schroeder, BM; Silver, SM; Sterns, RH, 2006)
"Aldosterone levels were much lower in ACTH deficiency patients during the hyponatremic state (33 +/- 40 pg/ml) when compared with the nonendocrine SIADH (120 +/- 60 pg/ml; P < 0."1.32Low plasma bicarbonate level in hyponatremia related to adrenocorticotropin deficiency. ( Decaux, G; Musch, W; Penninckx, R; Soupart, A, 2003)
"Ra urea was 5."1.30Effect of liver disease and transplantation on urea synthesis in humans: relationship to acid-base status. ( Jahoor, F; Shangraw, RE, 1999)
"Treatment with enalapril (n = 7) during pacing reduced the decrease in aortic flow by 33% and prevented changes in plasma urea, potassium, and sodium."1.28Converting enzyme inhibition by enalapril in experimental heart failure. ( Bassenge, E; Holtz, J; Munzel, T; Sommer, O, 1990)
"Reported successes in the treatment of hyponatremia due to SIADH by administration of urea and normal saline led to the authors' routine use of this therapy for hyponatremic neurosurgical patients."1.28Administration of intravenous urea and normal saline for the treatment of hyponatremia in neurosurgical patients. ( Harbaugh, RE; Reeder, RF, 1989)
"Urea treatment also induced a persistent osmotic diuresis, allowing a normal daily intake of water despite SIADH."1.26Treatment of the syndrome of inappropriate secretion of antidiuretic hormone by urea. ( Brimioulle, S; Decaux, G; Genette, F; Mockel, J, 1980)

Research

Studies (133)

TimeframeStudies, this research(%)All Research%
pre-199040 (30.08)18.7374
1990's18 (13.53)18.2507
2000's28 (21.05)29.6817
2010's32 (24.06)24.3611
2020's15 (11.28)2.80

Authors

AuthorsStudies
Martínez, Á1
Rodríguez, A1
Corral, M1
Reyes, E1
Rodríguez, S1
Klhůfek, J1
Šálek, T1
Bozkurt Babuş, S1
Köse, A1
Erdoğan, S1
Kiraz, M1
İyikesici, F1
Adrogué, HJ1
Tucker, BM1
Madias, NE2
Cui, J3
Halpin, K3
Paprocki, E3
Bioletto, F1
Varaldo, E1
Prencipe, N1
Benso, A1
Berton, AM1
Veligratli, F1
Alexandrou, D1
Shah, S1
Amin, R1
Dattani, M1
Gan, HW1
Famuboni, A1
Lopez-Garcia, C1
Trompeter, R1
Bockenhauer, D1
Li, P1
Kuo, N1
Patel, R1
Omary, MB1
Monnerat, S1
Atila, C1
Baur, F1
Santos de Jesus, J1
Refardt, J1
Dickenmann, M1
Christ-Crain, M2
Colombo, F1
Milani, M1
Rondon-Berrios, H1
Woudstra, J1
de Boer, MP1
Hempenius, L1
van Roon, EN1
Decaux, G33
Gankam Kengne, F3
González Pannia, P1
Balboa, R1
Navarro, R1
Nocita, MF1
Ferraro, M1
Mannucci, C1
Kettritz, R1
Cailleaux, A1
Mahieu, F1
Heinrichs, C2
Adams, B1
Ismaili, K1
Brachet, C2
Baldrighi, M1
Castello, LM1
Bartoli, E1
Bardanzellu, F1
Pintus, MC1
Masile, V1
Fanos, V2
Marcialis, MA2
Musch, W9
Berkman, K1
Haigh, K1
Li, L1
Lockett, J2
Dimeski, G2
Russell, A1
Inder, WJ2
Berkman, KE1
Russell, AW1
Nervo, A1
D'Angelo, V1
Rosso, D1
Castellana, E1
Cattel, F1
Arvat, E1
Grossi, E1
Hoorn, EJ1
Spasovski, G1
Salah, K1
Stienen, S1
Moons, AHM1
Bakx, ALM1
van Pol, PE1
Kortz, RAM1
Ferreira, JP1
Marques, I1
Schroeder-Tanka, JM1
Keijer, JT1
Bayes-Genis, A1
Pinto, YM1
Tijssen, JG1
Kok, WE1
Shchekochikhin, D1
Tkachenko, O1
Schrier, RW1
de Solà-Morales, O1
Riera, M1
Al Wakeel, JS1
Couturier, BS1
Soupart, A14
Frenkel, NJ1
Vogt, L1
De Rooij, SE1
Trimpert, C1
Levi, MM1
Deen, PM1
van den Born, BJ1
Greenberg, JH1
Tufro, A1
Marsenic, O1
Santiago Pérez, A1
Runkle de la Vega, I1
Peña Pedrosa, JA1
Arias Fernández, ML1
Sterns, RH3
Silver, SM3
Hix, JK1
Cairns, RS1
Hew-Butler, T1
Cuesta, M1
Hannon, MJ1
Thompson, CJ1
Annoni, F1
Fontana, V1
Brimioulle, S3
Creteur, J1
Vincent, JL1
Taccone, FS1
Nigro, N1
Winzeler, B1
Suter-Widmer, I1
Schuetz, P1
Arici, B1
Bally, M1
Blum, CA1
Nickel, CH1
Bingisser, R1
Bock, A1
Huber, A1
Müller, B1
Kawai, N1
Ishikawa, K1
Nemoto, K1
Katano, T1
Takahashi, S1
Hori, T1
Asada, T1
Dessì, A1
Contu, S1
Field, MJ1
Andres, C1
Varsavsky, M1
Quesada Charneco, M1
Rozas Moreno, P1
Lichtwarck-Aschoff, M1
Pippi, A1
Dietrich, B1
Hensen, J1
Chehade, H1
Rosato, L1
Girardin, E1
Cachat, F1
Coussement, J1
Danguy, C1
Zouaoui-Boudjeltia, K1
Defrance, P1
Bankir, L1
Biston, P1
Piagnerelli, M1
Coffernils, M2
Couturier, B1
Gankam-Kengne, F1
Vandergheynst, F1
Berl, T1
Edoute, Y1
Davids, MR1
Johnston, C1
Halperin, ML1
BATT, RE1
CIRKSENA, WJ1
LEBHERZ, TB1
WEIL, WB1
WALLACE, WM1
WILSON, JD1
CAMPION, DS1
NORTH, JD1
PAMPIGLIONE, G1
Penninckx, R1
Hedeshi, A1
Kazama, I1
Hatano, R1
Michimata, M1
Suzuki, K1
Arata, T1
Suzuki, M1
Miyama, N1
Sato, A1
Satomi, S1
Ejima, Y1
Sasaki, S1
Matsubara, M1
Gupta, BD1
Sharma, P1
Bagla, J1
Parakh, M1
Soni, JP1
Schroeder, BM1
Rojiani, AM1
Verhoeven, A1
Huang, EA1
Feldman, BJ1
Schwartz, ID1
Geller, DH1
Rosenthal, SM1
Gitelman, SE1
Gawlowski, Z1
Aladangady, N1
Coen, PG1
Barcia, RE1
Castiglia, NI1
Villaverde, ME1
Lanosa, GA1
Ujeda Mantello, CJ1
Aguirre, M1
Borello, GJ1
Caisson, AM1
Schroëder, B1
Liamis, G1
Christidis, D1
Alexandridis, G1
Bairaktari, E1
Elisaf, M1
Leblanc, PE1
Cheisson, G1
Geeraerts, T1
Tazarourte, K1
Duranteau, J1
Vigué, B1
Issa, VS1
Bacal, F1
Mangini, S1
Carneiro, RM1
Azevedo, CH1
Chizzola, PR1
Ferreira, SM1
Bocchi, EA1
Renneboog, B1
Fenske, W1
Störk, S1
Koschker, AC1
Blechschmidt, A1
Lorenz, D1
Wortmann, S1
Allolio, B1
Aviram, A1
Pfau, A1
Czaczkes, JW1
Ullmann, TD1
Knapp, MS1
Bhagat, CI1
Garcia-Webb, P1
Fletcher, E1
Beilby, JP1
Kamm, DE1
Genin, M1
Kuchmy, B1
Hollander, J1
Genette, F2
Mockel, J3
Wallerstedt, S1
Unger, J1
Thimpont, J1
Vandervelde, D1
Verhaeverbeke, I1
Berghmans, T1
Kelly, DF1
Laws, ER1
Fossett, D1
Schlesser, M1
Prospert, F4
Namias, B2
Kruse, JA1
Cadnapaphornchai, P1
Goldman, MB1
Robertson, GL1
Luchins, DJ1
Hedeker, D1
Poon, WS1
Lolin, YI1
Yeung, TF1
Yip, CP1
Goh, KY1
Lam, MK1
Cockram, C1
Hinchcliff, KW1
Reinhart, GA1
Burr, JR1
Swenson, RA1
Moonen, M1
Dechenne, C1
Rorive, G1
Swanepoel, CR1
Shangraw, RE1
Jahoor, F1
Fallon, KE1
Sivyer, G1
Sivyer, K1
Dare, A1
Silver, S1
Schroöeder, B1
Sterns, R1
Penney, MD1
Walters, G1
Wilkins, DG1
Morgan, DB1
Ball, SR1
Thomas, TH1
Lee, MR1
Arroyo, V1
Rodés, J1
Gutiérrez-Lizárraga, MA1
Revert, L1
Ruiz-Beltrán, R1
Herrero-Herrero, JI1
Macías, JF1
Graber, M1
Corish, D1
Stenuit, A1
Perier, O1
Cauchie, P3
Byatt, CM1
Millard, PH1
Levin, GE1
Holtz, J1
Munzel, T1
Sommer, O1
Bassenge, E1
Wise, BL1
Van Reeth, O1
Davis, C1
Reeder, RF1
Harbaugh, RE1
Gardes, J1
Gonzalez, MF1
Corvol, P1
Ménard, J1
Kinzie, BJ1
Lao, TT1
Loong, EP1
Chin, RK1
Vincken, W1
Mols, P2
Flamion, B1
Delwiche, F2
Borland, C1
Amadi, A1
Murphy, P1
Shallcross, T1
Cauchi, P1
Rösler, A1
Theodor, R1
Gazit, E1
Biochis, H1
Rabinowitz, D1
Flear, CT1
Senewiratne, B1
Sherlock, S1
Munro, AH1
Crompton, GK1
Mir, MA1
Delamore, IW1
Losowsky, MS1
Scott, BB1
Husband, P1
Howlett, KA1
Kingston, M1
Koppel, MH1
Coburn, JW1
Mims, MM1
Goldstein, H1
Boyle, JD1
Rubini, ME1
Wakim, KG2
Polak, A1
Cat, I1
Marçallo, FA1
Marinoni, LP1
Giraldi, DJ1
Costa, O1
Braga, H1
Zürcher, C1
Truniger, B1
Johnson, WJ1
Klass, DW1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Urea for Chronic Hyponatremia: A Pilot Study[NCT04588207]Phase 22 participants (Actual)Interventional2021-12-28Terminated (stopped due to Unable to recruit participants)
Hypotonic Hyponatremia: Criteria for the Correct Classification of Its Etiology and of Patient Volume Status at the Access in the Emergency Department and at the Subsequent Re-evaluation in Hospital Wards[NCT04402190]123 participants (Actual)Observational2018-06-01Completed
Research Project: Pilot Study on Oral Urea Use in Patients at High Risk of Kidney Stone Recurrence[NCT04727606]Phase 20 participants (Actual)Interventional2023-01-15Withdrawn (stopped due to We never got Health Canada approval)
Early Sodium Intake in Preterm Newborns; Randomized Clinical Trial[NCT04035564]Phase 452 participants (Actual)Interventional2018-03-30Completed
Hypertonic Saline Solution in Decompensated Heart Failure[NCT00555685]Phase 234 participants (Actual)Interventional2008-02-29Completed
[NCT00541944]120 participants (Anticipated)Observational2007-04-30Recruiting
Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic From Euvolemic Hyponatremia[NCT04744987]122 participants (Actual)Observational2019-07-30Completed
Post-Operative Water Load Following Transsphenoidal Pituitary Surgery[NCT02727686]30 participants (Actual)Interventional2016-03-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

% Weight Change

The difference between initial weight and 72hrs weight, expressed in percentage of birth weight. (NCT04035564)
Timeframe: Initial weight (baseline) vs 72 hours

Intervention% of birth weight (Mean)
Sodium < 1mEq/kg/Day-9.206
Sodium 5mEq/kg/Day-6.345

Change in Serum Sodium

The difference between current serum sodium and initial serum sodium (NCT04035564)
Timeframe: Initial serum sodium (baseline) vs 72 hours

InterventionmEq/L (Mean)
Sodium < 1mEq/kg/Day1.921
Sodium 5mEq/kg/Day5.71

Hypernatremia

serum sodium >150mEq/L (NCT04035564)
Timeframe: 72 hours

InterventionParticipants (Count of Participants)
Sodium < 1mEq/kg/Day1
Sodium 5mEq/kg/Day1

Hyponatremia

serum sodium <130mEq/L (NCT04035564)
Timeframe: 72 hours

InterventionParticipants (Count of Participants)
Sodium < 1mEq/kg/Day6
Sodium 5mEq/kg/Day1

Mortality

Death during hospitalization. (NCT04035564)
Timeframe: Patients will be followed during hospitalization, an expected average of 3 months of age

InterventionParticipants (Count of Participants)
Sodium < 1mEq/kg/Day5
Sodium 5mEq/kg/Day2

Number of Participants With Intraventricular Hemorrhage

Bleeding into the brain´s ventricular system (intracranial ultrasound). (NCT04035564)
Timeframe: Patients will be followed during hospitalization, an expected average of 3 months of age

InterventionParticipants (Count of Participants)
Sodium < 1mEq/kg/Day6
Sodium 5mEq/kg/Day4

Number of Participants With Late-onset Sepsis

Positive blood culture and/or 5 days of continuous antimicrobial therapy (NCT04035564)
Timeframe: Patients will be followed during hospitalization, an expected average of 3 months of age

InterventionParticipants (Count of Participants)
Sodium < 1mEq/kg/Day8
Sodium 5mEq/kg/Day5

Number of Participants With Necrotizing Enterocolitis

"Number of patients with Bell stage II or greater necrotizing enterocolitis~Bell's Staging:~Stage II A:~Gastrointestinal signs: Increasing gastric aspirates, mild abdominal distention, fecal occult blood, absent bowel sounds.~Systemic signs: Temperature instability, apnea, bradycardia, lethargy. Radiological findings: Intestinal dilatation, ileus, pneumatosis intestinalis.~Stage II B:~Gastrointestinal signs: As stage IIA plus abdominal tenderness. Systemic signs: As stage IIA plus metabolic acidosis and thrombocytopenia. Radiological findings: As stage IIA plus portal vein gas and ascites.~Stage III A:~Gastrointestinal signs: As stage IIB plus marked abdominal tenderness and generalised peritonitis.~Systemic signs: As stage IIB plus hypotension and severe apnea. Radiological findings: As stage IIB~Stage III B:~Gastrointestinal signs: As stage IIIA As stage IIIA As stage IIIA plus pneumoperitoneum" (NCT04035564)
Timeframe: Patients will be followed during hospitalization, an expected average of 3 months of age

InterventionParticipants (Count of Participants)
Sodium < 1mEq/kg/Day2
Sodium 5mEq/kg/Day2

Weight Change

The difference between current weight and initial weight (NCT04035564)
Timeframe: Initial weight (baseline) vs 72 hours

InterventionGrams (Mean)
Sodium < 1mEq/kg/Day-135.43
Sodium 5mEq/kg/Day-96.05

Reviews

23 reviews available for urea and Hyponatremia

ArticleYear
Diagnosis and Management of Hyponatremia: A Review.
    JAMA, 2022, 07-19, Volume: 328, Issue:3

    Topics: Coma; Heart Failure; Humans; Hyponatremia; Hypovolemia; Inappropriate ADH Syndrome; Prospective Stud

2022
Long-term efficacy of empagliflozin as an add-on treatment for chronic SIAD: a case report and literature review.
    Hormones (Athens, Greece), 2023, Volume: 22, Issue:2

    Topics: Aged; Diabetes Mellitus, Type 2; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Sodium; Ure

2023
Tolvaptan and urea in paediatric hyponatraemia.
    Pediatric nephrology (Berlin, Germany), 2024, Volume: 39, Issue:1

    Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Child; Humans; Hyponatremia; Inappropriate

2024
Urea for Chronic Hyponatremia.
    Blood purification, 2020, Volume: 49, Issue:1-2

    Topics: Chronic Disease; Diuretics; Humans; Hyponatremia; Urea

2020
Hypertonic saline, isotonic saline, water restriction, long loops diuretics, urea or vaptans to treat hyponatremia.
    Expert review of endocrinology & metabolism, 2020, Volume: 15, Issue:3

    Topics: Acute Disease; Antidiuretic Hormone Receptor Antagonists; Bicarbonates; Chronic Disease; Drinking; H

2020
Focus on neonatal and infantile onset of nephrogenic syndrome of inappropriate antidiuresis: 12 years later.
    Pediatric nephrology (Berlin, Germany), 2019, Volume: 34, Issue:5

    Topics: Age of Onset; Antidiuretic Hormone Receptor Antagonists; Clinical Trials as Topic; Diuretics, Osmoti

2019
Recent developments in the management of acute and chronic hyponatremia.
    Current opinion in nephrology and hypertension, 2019, Volume: 28, Issue:5

    Topics: Acute Disease; Antidiuretic Hormone Receptor Antagonists; Chronic Disease; Fluid Therapy; Humans; Hy

2019
Hyponatremia: an update on current pharmacotherapy.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:6

    Topics: Aged; Antidiuretic Hormone Receptor Antagonists; Brain Edema; Chronic Disease; Clinical Trials as To

2013
Urea for management of the syndrome of inappropriate secretion of ADH: A systematic review.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2014, Volume: 61, Issue:9

    Topics: Disease Management; Drug Evaluation; Evidence-Based Medicine; Humans; Hypernatremia; Hypokalemia; Hy

2014
Diagnosis and treatment of hyponatraemia in neurosurgical patients.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2016, Volume: 63, Issue:5

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Antidiuretic Hormone Receptor Antagonists; Brain

2016
Nephrogenic syndrome of inappropriate antidiuresis: a novel cause of euvolemic hypotonic hyponatremia in newborns. Diagnosis and practical management.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2009, Volume: 22 Suppl 3

    Topics: Administration, Oral; Diabetes Insipidus, Nephrogenic; Female; Fluid Therapy; Humans; Hyponatremia;

2009
[Treatment of hyponatremia: new developments and controversies].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:17

    Topics: Antidiuretic Hormone Receptor Antagonists; Benzazepines; Blood Volume; Drinking; Humans; Hyponatremi

2011
Long-term treatment of hyponatremic patients with nephrogenic syndrome of inappropriate antidiuresis: personal experience and review of published case reports.
    Nephron. Clinical practice, 2012, Volume: 120, Issue:3

    Topics: Adult; Aged; Diuretics; Furosemide; Genetic Diseases, X-Linked; Humans; Hyponatremia; Inappropriate

2012
An elderly patient with chronic hyponatremia.
    Clinical journal of the American Society of Nephrology : CJASN, 2013, Volume: 8, Issue:3

    Topics: Age Factors; Aged; Antidiuretic Hormone Receptor Antagonists; Biomarkers; Chronic Disease; Demeclocy

2013
Treatment of symptomatic hyponatremia.
    The American journal of the medical sciences, 2003, Volume: 326, Issue:1

    Topics: Brain; Humans; Hyponatremia; Risk Factors; Saline Solution, Hypertonic; Urea

2003
Brain volume regulation in response to hypo-osmolality and its correction.
    The American journal of medicine, 2006, Volume: 119, Issue:7 Suppl 1

    Topics: Acute Disease; Animals; Brain; Brain Edema; Chronic Disease; Demyelinating Diseases; Humans; Hyponat

2006
[Does cerebral salt wasting syndrome exist?].
    Annales francaises d'anesthesie et de reanimation, 2007, Volume: 26, Issue:11

    Topics: Adrenal Cortex Hormones; Blood Pressure; Brain Diseases; Diagnosis, Differential; Humans; Hyponatrem

2007
Clinical laboratory evaluation of the syndrome of inappropriate secretion of antidiuretic hormone.
    Clinical journal of the American Society of Nephrology : CJASN, 2008, Volume: 3, Issue:4

    Topics: Acid-Base Equilibrium; Bicarbonates; Biomarkers; Clinical Laboratory Techniques; Creatinine; Diagnos

2008
The serum osmole gap.
    Journal of critical care, 1994, Volume: 9, Issue:3

    Topics: Alcoholic Intoxication; Blood Glucose; Ethylene Glycols; Humans; Hyponatremia; Methanol; Osmolar Con

1994
[Treatment of severe hyponatremia (<120mEq/l)].
    Revue medicale de Bruxelles, 2001, Volume: 22, Issue:5

    Topics: Acute Disease; Chronic Disease; Demyelinating Diseases; Humans; Hyponatremia; Postoperative Complica

2001
Management of the syndrome of inappropriate secretion of antidiuretic hormone.
    Clinical pharmacy, 1987, Volume: 6, Issue:8

    Topics: Demeclocycline; Drug-Related Side Effects and Adverse Reactions; Humans; Hyponatremia; Inappropriate

1987
Hepatic encephalopathy.
    British medical journal, 1973, Aug-04, Volume: 3, Issue:5874

    Topics: Acetazolamide; Ammonia; Constipation; Diet Therapy; Electroencephalography; Gastrointestinal Hemorrh

1973
The pathophysiology of the dialysis disequilibrium syndrome.
    Mayo Clinic proceedings, 1969, Volume: 44, Issue:6

    Topics: Acute Kidney Injury; Animals; Brain Edema; Calcium; Carbon Dioxide; Cerebrospinal Fluid; Electroence

1969

Trials

7 trials available for urea and Hyponatremia

ArticleYear
Effect of protein supplementation on plasma sodium levels in the syndrome of inappropriate antidiuresis: a monocentric, open-label, proof-of-concept study-the TREASURE study.
    European journal of endocrinology, 2023, Aug-02, Volume: 189, Issue:2

    Topics: Creatinine; Dietary Supplements; Humans; Hyponatremia; Inappropriate ADH Syndrome; Powders; Sodium;

2023
Palatability of two different formulations of urea for the treatment of hyponatremia: A double-blind, randomized, cross-over study.
    Clinical nutrition ESPEN, 2023, Volume: 58

    Topics: Cross-Over Studies; Female; Humans; Hyponatremia; Male; Middle Aged; Taste Perception; Urea

2023
Oral urea treatment for polydipsia-hyponatremia syndrome in patients with schizophrenia.
    Journal of clinical psychopharmacology, 2009, Volume: 29, Issue:5

    Topics: Administration, Oral; Adult; Humans; Hyponatremia; Male; Middle Aged; Schizophrenia; Syndrome; Thirs

2009
Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antidiuretic Hormone Receptor Antagonists; Ben

2012
Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antidiuretic Hormone Receptor Antagonists; Ben

2012
Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antidiuretic Hormone Receptor Antagonists; Ben

2012
Efficacy and tolerance of urea compared with vaptans for long-term treatment of patients with SIADH.
    Clinical journal of the American Society of Nephrology : CJASN, 2012, Volume: 7, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antidiuretic Hormone Receptor Antagonists; Ben

2012
Treatment of the polydipsia-hyponatremia syndrome with urea.
    The Journal of clinical psychiatry, 2005, Volume: 66, Issue:11

    Topics: Administration, Oral; Adult; Aged; Body Weight; Circadian Rhythm; Comorbidity; Creatine; Drinking; D

2005
Hypertonic saline solution for renal failure prevention in patients with decompensated heart failure.
    Arquivos brasileiros de cardiologia, 2007, Volume: 89, Issue:4

    Topics: Biomarkers; Cardiotonic Agents; Creatinine; Diuretics; Dobutamine; Female; Furosemide; Heart Failure

2007
Difference in solute excretion during correction of hyponatremic patients with cirrhosis or syndrome of inappropriate secretion of antidiuretic hormone by oral vasopressin V2 receptor antagonist VPA-985.
    The Journal of laboratory and clinical medicine, 2001, Volume: 138, Issue:1

    Topics: Antidiuretic Hormone Receptor Antagonists; Azepines; Benzamides; Diuresis; Humans; Hyponatremia; Ina

2001

Other Studies

103 other studies available for urea and Hyponatremia

ArticleYear
Hyponatremia treatment with oral urea in heart failure.
    Endocrinologia, diabetes y nutricion, 2022, Volume: 69, Issue:4

    Topics: Heart Failure; Humans; Hyponatremia; Urea

2022
Thiazide-associated hyponatremia in internal medicine patients: analysis of epidemiological and biochemical profiles.
    Postgraduate medicine, 2022, Volume: 134, Issue:5

    Topics: Anorexia; Creatinine; Female; Furosemide; Humans; Hyponatremia; Hypovolemia; Internal Medicine; Male

2022
Risk factors and mortality in elderly patients with severe hyponatremia admitted to the emergency department.
    Irish journal of medical science, 2023, Volume: 192, Issue:2

    Topics: Aged; C-Reactive Protein; Emergency Service, Hospital; Humans; Hyponatremia; Liver Cirrhosis; Retros

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Urea as safe treatment for hyponatremia due to syndrome of inappropriate antidiuretic hormone in infant with solitary central incisor and neurofibromatosis-1.
    Journal of pediatric endocrinology & metabolism : JPEM, 2023, Apr-25, Volume: 36, Issue:4

    Topics: Child; Humans; Hyponatremia; Inappropriate ADH Syndrome; Incisor; Infant; Neurofibromatosis 1; Urea;

2023
Hypoosmosis alters hepatocyte mitochondrial morphology and induces selective release of carbamoyl phosphate synthetase 1.
    American journal of physiology. Gastrointestinal and liver physiology, 2023, 10-01, Volume: 325, Issue:4

    Topics: Animals; Carbamoyl-Phosphate Synthase (Ammonia); Carbamyl Phosphate; Cytochromes c; Hepatocytes; Hyp

2023
Urea for hyponatraemia due to the syndrome of inappropriate antidiuretic hormone secretion.
    The Netherlands journal of medicine, 2020, Volume: 78, Issue:3

    Topics: Aged; Aged, 80 and over; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged

2020
Prevalence of cerebral edema among diabetic ketoacidosis patients.
    Archivos argentinos de pediatria, 2020, Volume: 118, Issue:5

    Topics: Adolescent; Argentina; Brain Edema; Child; Child, Preschool; Cross-Sectional Studies; Diabetic Ketoa

2020
[Hyponatremia - causes, diagnostic evaluation and treatment].
    Deutsche medizinische Wochenschrift (1946), 2021, Volume: 146, Issue:3

    Topics: Humans; Hyponatremia; Sodium; Sodium-Glucose Transporter 2 Inhibitors; Urea

2021
[Nephrogenic syndrome of inappropriate antidiuresis: Early diagnosis avoids severe hyponatremia complications].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2017, Volume: 24, Issue:7

    Topics: Early Diagnosis; Genetic Diseases, X-Linked; Humans; Hyponatremia; Inappropriate ADH Syndrome; Infan

2017
Comment on "Mild water restriction with or without urea for the longterm treatment of SIADH: Can urine osmolality help the choice?" by Decaux et al.
    European journal of internal medicine, 2018, Volume: 52

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Osmolar Concentration; Urea; Water

2018
High fractional potassium excretion in symptomatic hyponatremia.
    European journal of internal medicine, 2019, Volume: 59

    Topics: Aged; Diuretics; Humans; Hyponatremia; Inappropriate ADH Syndrome; Middle Aged; Polydipsia; Potassiu

2019
Investigation and management of moderate to severe inpatient hyponatraemia in an Australian tertiary hospital.
    BMC endocrine disorders, 2018, Dec-06, Volume: 18, Issue:1

    Topics: Aged; Cohort Studies; Disease Management; Female; Fluid Therapy; Hospitalization; Humans; Hyponatrem

2018
Urea treatment in fluid restriction-refractory hyponatraemia.
    Clinical endocrinology, 2019, Volume: 90, Issue:4

    Topics: Aged; Female; Humans; Hyponatremia; Male; Middle Aged; Sodium; Tertiary Care Centers; Treatment Outc

2019
Urea in cancer patients with chronic SIAD-induced hyponatremia: Old drug, new evidence.
    Clinical endocrinology, 2019, Volume: 90, Issue:6

    Topics: Aged; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged; Neoplasms; Retros

2019
Hyponatremia secondary to transient renal salt wasting (TRSW): A not so uncommon observation in the elderly
.
    Clinical nephrology, 2019, Volume: 91, Issue:6

    Topics: Aged; Aged, 80 and over; Calcium; Diuresis; Diuretics; Female; Fluid Therapy; Humans; Hyponatremia;

2019
External Validation of the ELAN-HF Score, Predicting 6-Month All-Cause Mortality in Patients Hospitalized for Acute Decompensated Heart Failure.
    Journal of the American Heart Association, 2019, 07-16, Volume: 8, Issue:14

    Topics: Acute Disease; Age Factors; Aged; Blood Pressure; Cause of Death; Edema; Female; Heart Failure; Hosp

2019
Kidney function and metabolic profile of chronic kidney disease and hemodialysis patients during Ramadan fasting.
    Iranian journal of kidney diseases, 2014, Volume: 8, Issue:4

    Topics: Adult; Aged; Blood Pressure; Blood Urea Nitrogen; Body Weight; Creatinine; Erythrocyte Count; Fastin

2014
Urea minimizes brain complications following rapid correction of chronic hyponatremia compared with vasopressin antagonist or hypertonic saline.
    Kidney international, 2015, Volume: 87, Issue:2

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Astrocytes; Benzamides; Blood-Brain Barrier; Bra

2015
Thiazide-induced hyponatraemia is associated with increased water intake and impaired urea-mediated water excretion at low plasma antidiuretic hormone and urine aquaporin-2.
    Journal of hypertension, 2015, Volume: 33, Issue:3

    Topics: Aged; Aged, 80 and over; Aquaporin 2; Drinking; Electrolytes; Female; Humans; Hydrochlorothiazide; H

2015
Approach to the treatment of the infant with hyponatremia.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2015, Volume: 65, Issue:3

    Topics: Humans; Hyponatremia; Infant; Male; Sodium; Treatment Outcome; Urea

2015
[Response to clinical case report: treatment with urea as an alternative to tolvaptan for the syndrome of inappropriate secretion of antidiuretic hormone].
    Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria, 2014, Nov-03, Volume: 38, Issue:6

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Urea; Vasopressins

2014
Urea for hyponatremia?
    Kidney international, 2015, Volume: 87, Issue:2

    Topics: Animals; Hyponatremia; Male; Urea

2015
Proof of concept: hypovolemic hyponatremia may precede and augment creatine kinase elevations during an ultramarathon.
    European journal of applied physiology, 2016, Volume: 116, Issue:3

    Topics: Adult; Creatine Kinase; Humans; Hyponatremia; Hypovolemia; Male; Middle Aged; Physical Exertion; Rha

2016
Early Effects of Enteral Urea on Intracranial Pressure in Patients With Acute Brain Injury and Hyponatremia.
    Journal of neurosurgical anesthesiology, 2017, Volume: 29, Issue:4

    Topics: Acute Disease; Adult; Aged; APACHE; Brain Injuries; Female; Humans; Hyponatremia; Inappropriate ADH

2017
Evaluation of copeptin and commonly used laboratory parameters for the differential diagnosis of profound hyponatraemia in hospitalized patients: 'The Co-MED Study'.
    Clinical endocrinology, 2017, Volume: 86, Issue:3

    Topics: Aged; Aged, 80 and over; Diagnosis, Differential; Glycopeptides; Hospitalization; Humans; Hydrocorti

2017
Comment on "Does 'asymptomatic hyponatremia' exist?".
    Nature reviews. Nephrology, 2010, Volume: 6, Issue:6

    Topics: Humans; Hyponatremia; Terminology as Topic; Urea

2010
Treatment of euvolemic hyponatremia in the intensive care unit by urea.
    Critical care (London, England), 2010, Volume: 14, Issue:5

    Topics: Aged; Aged, 80 and over; Female; Humans; Hyponatremia; Intensive Care Units; Male; Middle Aged; Retr

2010
[Urea as therapeutic option for the treatment of the syndrome of inappropriate antidiuretic hormone secretion].
    Medicina clinica, 2011, Jul-23, Volume: 137, Issue:5

    Topics: Amitriptyline; Carbamazepine; Comorbidity; Demeclocycline; Diabetic Neuropathies; Diuretics; Furosem

2011
[Supplement to continuing medical education article "Dysnatremia in intensive care patients"].
    Der Anaesthesist, 2011, Volume: 60, Issue:4

    Topics: Critical Care; Humans; Hyponatremia; Inappropriate ADH Syndrome; Osmolar Concentration; Urea; Vasopr

2011
Inappropriate antidiuretic hormone secretion: long-term successful urea treatment.
    Acta paediatrica (Oslo, Norway : 1992), 2012, Volume: 101, Issue:1

    Topics: Child, Preschool; Chronic Disease; Diuretics, Osmotic; Female; Humans; Hyponatremia; Inappropriate A

2012
Treatment of the syndrome of inappropriate secretion of antidiuretic hormone with urea in critically ill patients.
    American journal of nephrology, 2012, Volume: 35, Issue:3

    Topics: Adult; Aged; Critical Illness; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middl

2012
An integrative physiological approach to polyuria and hyponatraemia: a 'double-take' on the diagnosis and therapy in a patient with schizophrenia.
    QJM : monthly journal of the Association of Physicians, 2003, Volume: 96, Issue:7

    Topics: Adult; Diabetes Insipidus; Diagnosis, Differential; Diuresis; Humans; Hyponatremia; Male; Polyuria;

2003
GOUT AND SALT-WASTING RENAL DISEASE DURING PREGNANCY; DIAGNOSIS, MANAGEMENT, AND FOLLOW-UP.
    JAMA, 1963, Nov-30, Volume: 186

    Topics: Blood Chemical Analysis; Colchicine; Diet Therapy; Diet, Sodium-Restricted; Female; Follow-Up Studie

1963
FLUID THERAPY IN RENAL DISEASE.
    Pediatric clinics of North America, 1964, Volume: 11

    Topics: Acute Kidney Injury; Child; Diuresis; Fluid Therapy; Glomerulonephritis; Humans; Hyperkalemia; Hypoc

1964
PERITONEAL DIALYSIS AND RENAL FAILURE.
    The New Zealand medical journal, 1965, Volume: 64

    Topics: Acute Kidney Injury; Anuria; Blood; Creatine; Creatinine; Dialysis; Glomerulonephritis; Heart Failur

1965
ELECTROENCEPHALOGRAPHIC AND METABOLIC CHANGES AFTER SURGICAL OPERATIONS.
    Lancet (London, England), 1965, Aug-07, Volume: 2, Issue:7406

    Topics: Bicarbonates; Blood; Child; Chlorides; Electroencephalography; Humans; Hypokalemia; Hyponatremia; Me

1965
Low plasma bicarbonate level in hyponatremia related to adrenocorticotropin deficiency.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:11

    Topics: Adrenocorticotropic Hormone; Aged; Aged, 80 and over; Aldosterone; Bicarbonates; Carbon Dioxide; Dia

2003
Low sodium excretion in SIADH patients with low diuresis.
    Nephron. Physiology, 2004, Volume: 96, Issue:1

    Topics: Aged; Alcohol Withdrawal Seizures; Alcoholism; Creatinine; Diagnosis, Differential; Diuresis; Duoden

2004
BSC1 inhibition complements effects of vasopressin V2 receptor antagonist on hyponatremia in SIADH rats.
    Kidney international, 2005, Volume: 67, Issue:5

    Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Aquaporin 2; Aquaporins; Benzazepines; Deamino A

2005
Renal failure in asphyxiated neonates.
    Indian pediatrics, 2005, Volume: 42, Issue:9

    Topics: Acute Kidney Injury; Apgar Score; Asphyxia Neonatorum; Birth Weight; Case-Control Studies; Causality

2005
Myoinositol administration improves survival and reduces myelinolysis after rapid correction of chronic hyponatremia in rats.
    Journal of neuropathology and experimental neurology, 2006, Volume: 65, Issue:1

    Topics: Animals; Arginine Vasopressin; Behavior, Animal; Blood Glucose; Brain; Demyelinating Diseases; Disea

2006
Oral urea for the treatment of chronic syndrome of inappropriate antidiuresis in children.
    The Journal of pediatrics, 2006, Volume: 148, Issue:1

    Topics: Administration, Oral; Chronic Disease; Dose-Response Relationship, Drug; Female; Humans; Hyponatremi

2006
Urea treatment for exercise-associated hyponatremia.
    Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine, 2006, Volume: 16, Issue:3

    Topics: Administration, Oral; Exercise; Humans; Hyponatremia; Infusions, Intravenous; Urea

2006
Hypernatraemia in preterm infants born at less than 27 weeks gestation.
    Journal of paediatrics and child health, 2006, Volume: 42, Issue:12

    Topics: Birth Weight; Creatine; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing; Female; Fluid Therapy

2006
[Hyponatremia as a risk factor of death in patients with community-acquired pneumonia requiring hospitalization].
    Medicina, 2006, Volume: 66, Issue:6

    Topics: Adult; APACHE; Argentina; Cerebrovascular Disorders; Community-Acquired Infections; Epidemiologic Me

2006
Treatment of hyponatraemia by urea decreases risks of brain complications in rats. Brain osmolyte contents analysis.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2007, Volume: 22, Issue:7

    Topics: Animals; Betaine; Body Water; Brain; Brain Diseases; Demyelinating Diseases; Electrolytes; Hyponatre

2007
Uric acid homeostasis in the evaluation of diuretic-induced hyponatremia.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2007, Volume: 55, Issue:1

    Topics: Aged; Creatinine; Diagnosis, Differential; Diuretics; Edema; Female; Humans; Hyponatremia; Hypovolem

2007
Idiopathic hyponatremia in a young patient: look at the sinus.
    The American journal of medicine, 2008, Volume: 121, Issue:5

    Topics: Adult; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Neuroblastoma; Radiography; Urea

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Value of fractional uric acid excretion in differential diagnosis of hyponatremic patients on diuretics.
    The Journal of clinical endocrinology and metabolism, 2008, Volume: 93, Issue:8

    Topics: Aged; Diagnosis, Differential; Diuretics; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome;

2008
Hyperosmolality with hyponatremia, caused by inappropriate administration of mannitol.
    The American journal of medicine, 1967, Volume: 42, Issue:4

    Topics: Acute Kidney Injury; Aged; Blood Chemical Analysis; Body Weight; Humans; Hyponatremia; Iatrogenic Di

1967
Saline depletion, pre-renal failure and acute renal failure.
    Clinics in endocrinology and metabolism, 1984, Volume: 13, Issue:2

    Topics: Acute Kidney Injury; Adolescent; Calcium; Creatinine; Female; Humans; Hypernatremia; Hyponatremia; P

1984
Calculated vs measured plasma osmolalities revisited.
    Clinical chemistry, 1984, Volume: 30, Issue:10

    Topics: Blood Chemical Analysis; Blood Glucose; Diabetes Mellitus; Humans; Hypernatremia; Hyponatremia; Kidn

1984
Diuretic-induced azotemia: unmasking the role of increased peripheral catabolism through evisceration-hepatectomy.
    Kidney international. Supplement, 1983, Volume: 16

    Topics: Amino Acids; Animals; Furosemide; Hepatectomy; Hyponatremia; Intestines; Metabolic Clearance Rate; M

1983
Hypouremia in the syndrome of inappropriate secretion of antidiuretic hormone.
    Annals of internal medicine, 1980, Volume: 93, Issue:5

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Urea; Vasopressins

1980
[Hyponatremia in clinical practice].
    Lakartidningen, 1981, Nov-18, Volume: 78, Issue:47

    Topics: Humans; Hyponatremia; Inappropriate ADH Syndrome; Urea

1981
Treatment of the syndrome of inappropriate secretion of antidiuretic hormone by urea.
    The American journal of medicine, 1980, Volume: 69, Issue:1

    Topics: Adult; Aged; Body Weight; Diuresis; Drinking; Humans; Hyponatremia; Inappropriate ADH Syndrome; Kidn

1980
Urea therapy for inappropriate antidiuretic hormone secretion from tuberculous meningitis.
    JAMA, 1980, Aug-08, Volume: 244, Issue:6

    Topics: Brain Edema; Diuresis; Humans; Hypertension; Hyponatremia; Inappropriate ADH Syndrome; Intracranial

1980
Combined fractional excretion of sodium and urea better predicts response to saline in hyponatremia than do usual clinical and biochemical parameters.
    The American journal of medicine, 1995, Volume: 99, Issue:4

    Topics: Aged; Aged, 80 and over; Aldosterone; Creatinine; Diuretics; Drinking Behavior; Extracellular Space;

1995
Delayed hyponatremia after transsphenoidal surgery for pituitary adenoma. Report of nine cases.
    Journal of neurosurgery, 1995, Volume: 83, Issue:2

    Topics: Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Female; Humans; Hyponatremia; Male; Midd

1995
Uric acid, anion gap and urea concentration in the diagnostic approach to hyponatremia.
    Clinical nephrology, 1994, Volume: 42, Issue:2

    Topics: Acid-Base Equilibrium; Diuretics; Heart Failure; Humans; Hyponatremia; Hypopituitarism; Inappropriat

1994
Effect of urea and indomethacin intake on solute excretion in the syndrome of inappropriate secretion of antidiuretic hormone.
    Nephron, 1993, Volume: 64, Issue:1

    Topics: Aged; Chlorides; Humans; Hyponatremia; Inappropriate ADH Syndrome; Indomethacin; Middle Aged; Natriu

1993
The influence of polydipsia on water excretion in hyponatremic, polydipsic, schizophrenic patients.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:4

    Topics: Adult; Blood Glucose; Blood Pressure; Creatinine; Female; Humans; Hyponatremia; Male; Middle Aged; P

1996
Water and sodium disorders following surgical excision of pituitary region tumours.
    Acta neurochirurgica, 1996, Volume: 138, Issue:8

    Topics: Adolescent; Adult; Aged; Atrial Natriuretic Factor; Child; Creatinine; Deamino Arginine Vasopressin;

1996
Exercise-associated hyponatremia in Alaskan sled dogs: urinary and hormonal responses.
    Journal of applied physiology (Bethesda, Md. : 1985), 1997, Volume: 83, Issue:3

    Topics: Animals; Body Weight; Diet; Diuresis; Dogs; Eating; Energy Metabolism; Female; Hormones; Hyponatremi

1997
[Clinical case of the month. Acute renal insufficiency following ethylene glycol poisoning].
    Revue medicale de Liege, 1997, Volume: 52, Issue:9

    Topics: Acute Kidney Injury; Anuria; Calcium Oxalate; Creatinine; Ethylene Glycol; Humans; Hyponatremia; Kid

1997
Creatinine, electrolytes and urea--do I hear much groaning?
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1999, Volume: 89, Issue:3

    Topics: Creatinine; Humans; Hyperkalemia; Hypernatremia; Hypokalemia; Hyponatremia; Urea

1999
Effect of liver disease and transplantation on urea synthesis in humans: relationship to acid-base status.
    The American journal of physiology, 1999, Volume: 276, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Arteries; Bicarbonates; Carbon Dioxide; Female; Humans; Hydrogen-Ion C

1999
The biochemistry of runners in a 1600 km ultramarathon.
    British journal of sports medicine, 1999, Volume: 33, Issue:4

    Topics: Adult; Aged; Alanine Transaminase; Alkaline Phosphatase; Aspartate Aminotransferases; Bilirubin; Blo

1999
Evidence that chronicity of hyponatremia contributes to the high urate clearance observed in the syndrome of inappropriate antidiuretic hormone secretion.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2000, Volume: 36, Issue:4

    Topics: Adult; Aged; Case-Control Studies; Chronic Disease; Glomerular Filtration Rate; Humans; Hyponatremia

2000
Re: hyponatremia.
    Clinical endocrinology, 2001, Volume: 54, Issue:6

    Topics: Drug Administration Schedule; Humans; Hyponatremia; Saline Solution, Hypertonic; Urea

2001
Utility and limitations of biochemical parameters in the evaluation of hyponatremia in the elderly.
    International urology and nephrology, 2001, Volume: 32, Issue:3

    Topics: Aged; Aged, 80 and over; Aldosterone; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Isot

2001
Rapid (24-hour) reaccumulation of brain organic osmolytes (particularly myo-inositol) in azotemic rats after correction of chronic hyponatremia.
    Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:6

    Topics: Animals; Body Water; Brain; Chronic Disease; Hyponatremia; Inositol; Male; Mercuric Chloride; Potass

2002
Hyponatraemia in patients with head injury.
    Intensive care medicine, 1979, Volume: 5, Issue:1

    Topics: Adult; Craniocerebral Trauma; Extracellular Space; Female; Humans; Hyponatremia; Male; Sodium; Urea;

1979
Sodium losing renal disease: Two cases and a review of the literature.
    The Quarterly journal of medicine, 1978, Volume: 47, Issue:185

    Topics: Adult; Drinking; Humans; Hyponatremia; Kidney Diseases; Male; Middle Aged; Sodium; Urea; Urinary Bla

1978
Prognostic value of spontaneous hyponatremia in cirrhosis with ascites.
    The American journal of digestive diseases, 1976, Volume: 21, Issue:3

    Topics: Bilirubin; Diuresis; Humans; Hyponatremia; Kidney Function Tests; Liver Cirrhosis; Prognosis; Serum

1976
Mechanism of low serum sodium levels in Mediterranean spotted fever.
    Acta tropica, 1991, Volume: 50, Issue:2

    Topics: Adolescent; Adult; Aged; Boutonneuse Fever; Chlorides; Creatinine; Female; Hematuria; Humans; Hypona

1991
The electrolytes in hyponatremia.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1991, Volume: 18, Issue:5

    Topics: Adaptation, Physiological; Animals; Atrial Natriuretic Factor; Bicarbonates; Extracellular Space; Hu

1991
Limits of brain tolerance to daily increments in serum sodium in chronically hyponatraemic rats treated with hypertonic saline or urea: advantages of urea.
    Clinical science (London, England : 1979), 1991, Volume: 80, Issue:1

    Topics: Animals; Brain; Chronic Disease; Demyelinating Diseases; Hyponatremia; Male; Rats; Rats, Inbred Stra

1991
Dissociation between uric acid and urea clearances in the syndrome of inappropriate secretion of antidiuretic hormone related to salt excretion.
    Clinical science (London, England : 1979), 1990, Volume: 78, Issue:5

    Topics: Adult; Humans; Hyponatremia; Inappropriate ADH Syndrome; Middle Aged; Osmolar Concentration; Prospec

1990
Diuretics and electrolyte disturbances in 1000 consecutive geriatric admissions.
    Journal of the Royal Society of Medicine, 1990, Volume: 83, Issue:11

    Topics: Age Factors; Aged; Amiloride; Diuretics; Drug Combinations; Drug Prescriptions; Humans; Hydrochlorot

1990
Converting enzyme inhibition by enalapril in experimental heart failure.
    Nephron, 1990, Volume: 55 Suppl 1

    Topics: Administration, Oral; Animals; Cardiac Output, Low; Cardiac Pacing, Artificial; Creatinine; Dogs; En

1990
Intravenous urea and saline for hyponatremia.
    Journal of neurosurgery, 1989, Volume: 71, Issue:2

    Topics: Humans; Hyponatremia; Sodium Chloride; Urea

1989
Rapid correction of hyponatraemia with urea may protect against brain damage in rats.
    Clinical science (London, England : 1979), 1989, Volume: 77, Issue:3

    Topics: Animals; Brain; Brain Diseases; Hyponatremia; Male; Rats; Rats, Inbred Strains; Saline Solution, Hyp

1989
Hyponatremia treatment by urea and saline.
    Journal of neurosurgery, 1989, Volume: 71, Issue:5 Pt 1

    Topics: Humans; Hyponatremia; Sodium Chloride; Urea

1989
Administration of intravenous urea and normal saline for the treatment of hyponatremia in neurosurgical patients.
    Journal of neurosurgery, 1989, Volume: 70, Issue:2

    Topics: Blood Urea Nitrogen; Humans; Hyponatremia; Inappropriate ADH Syndrome; Injections, Intravenous; Nerv

1989
Influence of converting enzyme inhibition on the hormonal and renal adaptation to hyper- and hyponatraemic dehydration.
    Journal of hypertension, 1986, Volume: 4, Issue:2

    Topics: Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dehydrati

1986
Intrapartum fluid administration and sodium concentration in maternal and umbilical cord plasma.
    European journal of obstetrics, gynecology, and reproductive biology, 1987, Volume: 25, Issue:4

    Topics: Female; Fetal Blood; Glucose; Humans; Hyponatremia; Labor, Obstetric; Oxytocin; Pharmaceutical Vehic

1987
Urea treatment for water retention in hyponatremic congestive heart failure.
    International journal of cardiology, 1987, Volume: 17, Issue:1

    Topics: Aged; Drug Therapy, Combination; Furosemide; Heart Failure; Humans; Hyponatremia; Male; Urea

1987
Treatment of hyponatremic cirrhosis with ascites resistant to diuretics by urea.
    Nephron, 1986, Volume: 44, Issue:4

    Topics: Adult; Ascites; Body Weight; Creatinine; Drug Therapy, Combination; Edema; Furosemide; Humans; Hypon

1986
Biochemical and clinical correlates of diuretic therapy in the elderly.
    Age and ageing, 1986, Volume: 15, Issue:6

    Topics: Aged; Airway Obstruction; Coronary Disease; Creatinine; Diuretics; Heart Failure; Humans; Hypokalemi

1986
Use of urea for treatment of water retention in hyponatraemic cirrhosis with ascites resistant to diuretics.
    British medical journal (Clinical research ed.), 1985, Jun-15, Volume: 290, Issue:6484

    Topics: Diuretics; Edema; Female; Humans; Hyponatremia; Liver Cirrhosis, Alcoholic; Middle Aged; Urea

1985
Salt wasting, raised plasma-renin activity, and normal or high plasma-aldosterone: a form of pseudohypoaldosteronism.
    Lancet (London, England), 1973, May-05, Volume: 1, Issue:7810

    Topics: Acidosis; Aldosterone; Bicarbonates; Blood Urea Nitrogen; Carbon Dioxide; Child; Child, Preschool; D

1973
Letter: Hyponatraemia.
    Lancet (London, England), 1974, Jul-20, Volume: 2, Issue:7873

    Topics: Blood Glucose; Cell Membrane Permeability; Humans; Hydrogen-Ion Concentration; Hyponatremia; Osmolar

1974
Amiloride ('MK 870') in patients with ascites due to cirrhosis of the liver.
    Lancet (London, England), 1968, Jan-20, Volume: 1, Issue:7534

    Topics: Adult; Ascites; Bicarbonates; Creatinine; Diuretics; Ethacrynic Acid; Furosemide; Guanidines; Humans

1968
Inappropriate antidiuretic hormone secretion in oat-cell carcinoma of bronchus. Aggravation of hyponatraemia by intravenous cyclophosphamide.
    Thorax, 1972, Volume: 27, Issue:5

    Topics: Adult; Autopsy; Bicarbonates; Bronchial Neoplasms; Carcinoma, Bronchogenic; Carcinoma, Small Cell; C

1972
Hyponatraemia syndrome in acute myeloid leukaemia.
    British medical journal, 1974, Jan-12, Volume: 1, Issue:5897

    Topics: Adult; Ampicillin; Blood Cell Count; Body Weight; Bone Marrow Cells; Chlorides; Cloxacillin; Cytarab

1974
Renal papillary necrosis in infancy.
    Archives of disease in childhood, 1973, Volume: 48, Issue:2

    Topics: Acidosis; Acute Disease; Anuria; Bicarbonates; Body Weight; Dehydration; Humans; Hyponatremia; Infan

1973
Electrolyte disturbances in Liberian children with kwashiorkor.
    The Journal of pediatrics, 1973, Volume: 83, Issue:5

    Topics: Alkalies; Alkalosis; Arteries; Blood; Calcium; Child; Child, Preschool; Chlorides; Chloroquine; Cult

1973
Transplantation of cadaveric kidneys from patients with hepatorenal syndrome. Evidence for the functionalnature of renal failure in advanced liver disease.
    The New England journal of medicine, 1969, Jun-19, Volume: 280, Issue:25

    Topics: Adult; Anuria; Blood Urea Nitrogen; Cadaver; Creatinine; Diuresis; Female; Humans; Hyponatremia; Kid

1969
Sodium depletion in chronic renal failure.
    Journal of the Royal College of Physicians of London, 1971, Volume: 5, Issue:4

    Topics: Blood Pressure Determination; Blood Proteins; Glomerular Filtration Rate; Hemoglobins; Humans; Hypon

1971
Syndrome of cellular agony--biochemical characterization.
    Helvetica paediatrica acta, 1969, Volume: 24, Issue:5

    Topics: Autopsy; Child; Death; Gastroenteritis; Humans; Hyperglycemia; Hyperkalemia; Hyponatremia; Kwashiork

1969
Body fluid composition and sodium excretion under osmotic diuresis.
    Helvetica medica acta, 1970, Volume: 35, Issue:4

    Topics: Adult; Body Fluids; Diuresis; Diuretics; Electrolytes; Extracellular Space; Female; Humans; Hypernat

1970
Role of blood urea and serum sodium concentrations in the pathogenesis of the dialysis dysequilibrium syndrome.
    Transactions - American Society for Artificial Internal Organs, 1968, Volume: 14

    Topics: Animals; Brain Chemistry; Cerebrospinal Fluid; Dogs; Electroencephalography; Hemodynamics; Humans; H

1968