Page last updated: 2024-10-21

urea and Hypokalemia

urea has been researched along with Hypokalemia in 49 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"The efficacy and safety of the novel calcium antagonist Amlodipine (Pfizer Laboratories, New York, New York) and hydrochlorothiazide were evaluated and compared in a randomized, single-blind, parallel group study in black Africans with essential hypertension."9.08The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with essential hypertension. ( Ajayi, AA; Akintomide, AO, 1995)
"The efficacy and safety of the novel calcium antagonist Amlodipine (Pfizer Laboratories, New York, New York) and hydrochlorothiazide were evaluated and compared in a randomized, single-blind, parallel group study in black Africans with essential hypertension."5.08The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with essential hypertension. ( Ajayi, AA; Akintomide, AO, 1995)
"Urea has been recently proposed for the management of hyponatremia linked to the syndrome of inappropriate secretion of ADH (SIADH)."4.90Urea for management of the syndrome of inappropriate secretion of ADH: A systematic review. ( de Solà-Morales, O; Riera, M, 2014)
" The combination of FAD 286 A (30 mg/kg) and furosemide (30 mg/kg) on the HS diet corrected the diuretic-induced hypokalemia (4."3.73Investigation of aldosterone-synthase inhibition in rats. ( Bissery, A; Gonzalez, MF; Guyene, TT; Ménard, J, 2006)
"The occurrence of renal failure is associated to an increased death risk."2.73Hypertonic saline solution for renal failure prevention in patients with decompensated heart failure. ( Azevedo, CH; Bacal, F; Bocchi, EA; Carneiro, RM; Chizzola, PR; Ferreira, SM; Issa, VS; Mangini, S, 2007)
" Nevertheless, in view of the potential seriousness of volume depletion, dosage should probably begin at 20 rather than 40 mg daily."1.26Adverse reactions to frusemide in hospital inpatients. ( Gray, J; Henry, DA; Lawson, DH; Lowe, J, 1979)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199036 (73.47)18.7374
1990's5 (10.20)18.2507
2000's4 (8.16)29.6817
2010's3 (6.12)24.3611
2020's1 (2.04)2.80

Authors

AuthorsStudies
Mikkelsen, ACD1
Thomsen, KL1
Vilstrup, H1
Aamann, L1
Jones, H1
Mookerjee, RP1
Hamilton-Dutoit, S1
Frystyk, J1
Aagaard, NK1
Bammigatti, C1
Surynarayana, BS1
Harichandra Kumar, KT1
Ganesh Kumar, S1
de Solà-Morales, O1
Riera, M1
BONDY, PK1
ENGEL, FL1
Palii, SP1
Contreras, CS1
Steill, JD1
Palii, SS1
Oomens, J1
Eyler, JR1
BRAY, GA1
NIENHUIS, LI1
MULMED, EI1
KELLEY, JW1
PERGOLA, F1
GALIAN, A1
BERNADES, P1
CACHIN, M1
MANGOS, JA1
OPITZ, JM1
LOBECK, CC1
COOKSON, DU1
JONES, FL1
PAMPIGLIONE, G1
Kedzierska, K1
Ciechanowski, K1
Gołembiewska, E1
Domański, L1
Kabat-Koperska, J1
Pietrzak-Nowacka, M1
Stepień-Korzonek, M1
Bober, J1
Ménard, J1
Gonzalez, MF1
Guyene, TT1
Bissery, A1
Issa, VS1
Bacal, F1
Mangini, S1
Carneiro, RM1
Azevedo, CH1
Chizzola, PR1
Ferreira, SM1
Bocchi, EA1
Ajayi, AA1
Akintomide, AO1
Donati-Genet, P1
Donati, R1
Colombo, JP1
Lüthy, CM1
Bianchetti, MG1
Swanepoel, CR1
Newman, LN1
Weiss, MF1
Berger, J1
Priester, A1
Negrea, LA1
Cacho, CP1
Lowe, J1
Gray, J1
Henry, DA1
Lawson, DH1
Cope, CL1
Loizou, S1
Leon, A1
Bain, SA1
Levick, WR1
Byatt, CM1
Millard, PH1
Levin, GE1
Borland, C1
Amadi, A1
Murphy, P1
Shallcross, T1
Soler, NG1
Bennett, MA1
FitzGerald, MG1
Malins, JM1
George, CF1
Breckenridge, AM1
Dollery, CT1
Senewiratne, B1
Sherlock, S1
Kofstad, J1
Froyshov, I1
Gjone, E1
Blix, S1
Bodin, F1
Liguory, C1
Capelle, P1
Conte, M1
Tarazi, RC1
Losowsky, MS1
Scott, BB1
Vetter, G1
MacFarlane, JP1
Kennedy, RD1
Zweig, JI1
Mills, IH1
Hofstetter, A1
Bjorneklett, A1
Taylor, RT1
Peaston, MJ1
Kingston, M1
Cummings, JH1
Sladen, GE1
James, OF1
Sarner, M1
Misiewicz, JJ1
Venter, JP1
Miyahara, M1
Fujise, Y1
Hoshikawa, K1
Nakagawa, K1
Radenbach, KL1
Antcliff, AC1
Hamilton, M1
Beevers, DG1
Harpur, JE1
Mitchell, AB1
Barnes, PC1
Leonard, JH1
Hesling, CM1
Schmidt, P1
Irsigler, K1
Mildschuh, W1
Pointner, H1
Kryspin-Exner, K1
Rastogi, SP1
Volans, G1
Elliott, RW1
Eccleston, DW1
Ashcroft, R1
Webster, D1
Kerr, DN1
Moffitt, EA1
Maher, FT1
Kirklin, JW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hypertonic Saline Solution in Decompensated Heart Failure[NCT00555685]Phase 234 participants (Actual)Interventional2008-02-29Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for urea and Hypokalemia

ArticleYear
Urea for management of the syndrome of inappropriate secretion of ADH: A systematic review.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2014, Volume: 61, Issue:9

    Topics: Disease Management; Drug Evaluation; Evidence-Based Medicine; Humans; Hypernatremia; Hypokalemia; Hy

2014
HEPATIC COMA; TREATMENT EMPHASIZING MERIT OF PERITONEAL DIALYSIS.
    American journal of surgery, 1963, Volume: 106

    Topics: Adrenal Cortex Hormones; Alkalosis; Ammonium Chloride; Anti-Bacterial Agents; Arginine; Chlorothiazi

1963
Hepatic encephalopathy.
    British medical journal, 1973, Aug-04, Volume: 3, Issue:5874

    Topics: Acetazolamide; Ammonia; Constipation; Diet Therapy; Electroencephalography; Gastrointestinal Hemorrh

1973
Effects of lysine on ammonia formation, hydrogen ion, and potassium ion balance: a review and an hypothesis.
    Clinical chemistry, 1973, Volume: 19, Issue:9

    Topics: Acid-Base Equilibrium; Adolescent; Adult; Ammonia; Animals; Arginine; Biological Transport; Cystinur

1973
Primary hyperaldosteronism.
    Clinics in endocrinology and metabolism, 1974, Volume: 3, Issue:3

    Topics: Adrenal Gland Neoplasms; Aldosterone; Corticosterone; Desoxycorticosterone; Electrocardiography; Hum

1974
[Effects and side-effects of hypotensive diuretics].
    Nihon rinsho. Japanese journal of clinical medicine, 1968, Volume: 26, Issue:7

    Topics: Antihypertensive Agents; Benzothiadiazines; Chlorothiazide; Diabetes Mellitus; Diuretics; Gout; Huma

1968

Trials

8 trials available for urea and Hypokalemia

ArticleYear
Hypertonic saline solution for renal failure prevention in patients with decompensated heart failure.
    Arquivos brasileiros de cardiologia, 2007, Volume: 89, Issue:4

    Topics: Biomarkers; Cardiotonic Agents; Creatinine; Diuretics; Dobutamine; Female; Furosemide; Heart Failure

2007
The efficacy and tolerability of amlodipine and hydrochlorothiazide in Nigerians with essential hypertension.
    Journal of the National Medical Association, 1995, Volume: 87, Issue:7

    Topics: Amlodipine; Blood Pressure; Drug Tolerance; Female; Heart Rate; Humans; Hydrochlorothiazide; Hyperte

1995
Comparison of the potassium- retaining effects of amiloride and spironolactone in hypertensive patients with thiazide-induced hypokalaemia.
    Lancet (London, England), 1973, Dec-08, Volume: 2, Issue:7841

    Topics: Adult; Aged; Amiloride; Blood Pressure; Body Weight; Diuretics; Drug Therapy, Combination; Female; H

1973
[Clinical testing of a new potassium-saving diuretic for the treatment of hypertension].
    Munchener medizinische Wochenschrift (1950), 1973, Dec-07, Volume: 115, Issue:49

    Topics: Aged; Amiloride; Blood Pressure; Body Weight; Clinical Trials as Topic; Creatinine; Diuretics; Drug

1973
The effects of amiloride during diuretic therapy in elderly subjects.
    Age and ageing, 1972, Volume: 1, Issue:2

    Topics: Administration, Oral; Aged; Amiloride; Calcium; Clinical Trials as Topic; Diuretics; Drug Combinatio

1972
Bumetanide, a new diuretic.
    International urology and nephrology, 1974, Volume: 6, Issue:1

    Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Benzoates; Bumetanide; Butylamines; Chlorides; Clinica

1974
Results of clinical studies with capreomycin, ethambutol and rifampicin in the Heckeshorn Hospital, Berlin.
    Scandinavian journal of respiratory diseases. Supplementum, 1969, Volume: 69

    Topics: Aged; Aminosalicylic Acids; Anti-Bacterial Agents; Berlin; Clinical Trials as Topic; Cycloserine; Dr

1969
Amiloride hydrochloride combined with hydrochlorothiazide in the control of hypertension and plasma potassium levels.
    The British journal of clinical practice, 1972, Volume: 26, Issue:9

    Topics: Alanine Transaminase; Amiloride; Aspartate Aminotransferases; Diuretics; Drug Combinations; Humans;

1972

Other Studies

35 other studies available for urea and Hypokalemia

ArticleYear
Potassium deficiency decreases the capacity for urea synthesis and markedly increases ammonia in rats.
    American journal of physiology. Gastrointestinal and liver physiology, 2021, 04-01, Volume: 320, Issue:4

    Topics: Ammonia; Animals; Disease Models, Animal; Female; Gene Expression Regulation, Enzymologic; Hyperammo

2021
Pattern and outcome of Cleistanthus collinus (Oduvanthalai) poisoning in a tertiary care teaching hospital in South India.
    Journal of forensic and legal medicine, 2013, Volume: 20, Issue:8

    Topics: Abdominal Pain; Adolescent; Adult; Age Distribution; Aged; Cell Count; Child; Euphorbiaceae; Female;

2013
Urea synthesis in the adrenalectomized-nephrectomized rat on low potassium diet.
    Federation proceedings, 1947, Volume: 6, Issue:1 Pt 2

    Topics: Adrenal Glands; Animals; Diet; Hypokalemia; Kidney; Potassium; Potassium Deficiency; Rats; Urea

1947
Triuret as a potential hypokalemic agent: Structure characterization of triuret and triuret-alkali metal adducts by mass spectrometric techniques.
    Archives of biochemistry and biophysics, 2010, Jun-01, Volume: 498, Issue:1

    Topics: Binding, Competitive; Chelating Agents; Hypokalemia; Isomerism; Ligands; Mass Spectrometry; Models,

2010
Effect of potassium depletion on distribution of urea and thiourea-C-14 in rat kidney.
    The American journal of physiology, 1963, Volume: 204

    Topics: Animals; Hypokalemia; Kidney; Potassium; Potassium Deficiency; Rats; Thiourea; Urea

1963
[HYPERCORTICISM AND BRONCHIAL CANCER WITH REVEALING HYPOKALEMIC ALKALOSIS].
    Bulletins et memoires de la Societe medicale des hopitaux de Paris, 1964, Jun-19, Volume: 115

    Topics: Adrenocortical Hyperfunction; Alkalosis; Ammonia; Bartter Syndrome; Blood Chemical Analysis; Blood G

1964
FAMILIAL JUVENILE NEPHRONOPHTHISIS. AN UNRECOGNIZED RENAL DISEASE IN THE UNITED STATES.
    Pediatrics, 1964, Volume: 34

    Topics: Adolescent; Blood; Blood Urea Nitrogen; Carbon Dioxide; Child; Chlorides; Consanguinity; Creatine; C

1964
MANAGEMENT OF COCCIDIOIDOMYCOSIS ON AN OPEN WARD.
    The American review of respiratory disease, 1965, Volume: 91

    Topics: Amphotericin B; Anemia; Blood Urea Nitrogen; Coccidioidomycosis; Drug Therapy; Fungi; Hypokalemia; L

1965
ELECTROENCEPHALOGRAPHIC AND METABOLIC CHANGES AFTER SURGICAL OPERATIONS.
    Lancet (London, England), 1965, Aug-07, Volume: 2, Issue:7406

    Topics: Bicarbonates; Blood; Child; Chlorides; Electroencephalography; Humans; Hypokalemia; Hyponatremia; Me

1965
Chronic hypokalaemia--how to establish a diagnosis?
    Acta medica Austriaca, 2003, Volume: 30, Issue:5

    Topics: Acid-Base Equilibrium; Adult; Aldosterone; Blood Pressure; Calcium; Chronic Disease; Creatinine; Dia

2003
Investigation of aldosterone-synthase inhibition in rats.
    Journal of hypertension, 2006, Volume: 24, Issue:6

    Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Cytochrome P-450 CYP11B2; Diuretics; Dose-Respons

2006
Urinary sodium, potassium, chloride, calcium, magnesium, phosphate, urate and urea in healthy subjects aged 5-18 years.
    Nephron, 1998, Volume: 78, Issue:2

    Topics: Acidosis, Renal Tubular; Adolescent; Calcium; Child; Child, Preschool; Chlorides; Electrolytes; Fema

1998
Creatinine, electrolytes and urea--do I hear much groaning?
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1999, Volume: 89, Issue:3

    Topics: Creatinine; Humans; Hyperkalemia; Hypernatremia; Hypokalemia; Hyponatremia; Urea

1999
The law of unintended consequences in action: increase in incidence of hypokalemia with improved adequacy of dialysis.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 2000, Volume: 16

    Topics: Creatinine; Humans; Hypokalemia; Peritoneal Dialysis; Potassium; Retrospective Studies; Urea

2000
Adverse reactions to frusemide in hospital inpatients.
    British medical journal, 1979, Aug-11, Volume: 2, Issue:6186

    Topics: Aged; Drug Administration Schedule; Female; Furosemide; Hospitalization; Humans; Hypokalemia; Male;

1979
Deoxycorticosterone excretion in normal, hypertensive and hypokalaemic subjects.
    Clinical science and molecular medicine, 1975, Volume: 48, Issue:2

    Topics: Aldosterone; Animals; Bicarbonates; Blood Pressure; Cross Reactions; Desoxycorticosterone; Humans; H

1975
Hypokalaemic episodic polymyopathy in cats fed a vegetarian diet.
    Australian veterinary journal, 1992, Volume: 69, Issue:10

    Topics: Amino Acids; Animals; Cat Diseases; Cats; Creatine Kinase; Creatinine; Diet, Vegetarian; Erythrocyte

1992
Diuretics and electrolyte disturbances in 1000 consecutive geriatric admissions.
    Journal of the Royal Society of Medicine, 1990, Volume: 83, Issue:11

    Topics: Age Factors; Aged; Amiloride; Diuretics; Drug Combinations; Drug Prescriptions; Humans; Hydrochlorot

1990
Biochemical and clinical correlates of diuretic therapy in the elderly.
    Age and ageing, 1986, Volume: 15, Issue:6

    Topics: Aged; Airway Obstruction; Coronary Disease; Creatinine; Diuretics; Heart Failure; Humans; Hypokalemi

1986
Intensive care in the management of diabetic ketoacidosis.
    Lancet (London, England), 1973, May-05, Volume: 1, Issue:7810

    Topics: Acute Kidney Injury; Adolescent; Adult; Age Factors; Blood Glucose; Child; Diabetic Ketoacidosis; Fe

1973
Amiloride ('MK 870') in patients with ascites due to cirrhosis of the liver.
    Lancet (London, England), 1968, Jan-20, Volume: 1, Issue:7534

    Topics: Adult; Ascites; Bicarbonates; Creatinine; Diuretics; Ethacrynic Acid; Furosemide; Guanidines; Humans

1968
Pancreatic tumor with intractable watery diarrhea, hypokalemia and hypercalcemia electrolyte balance studies.
    Scandinavian journal of gastroenterology, 1967, Volume: 2, Issue:4

    Topics: Adenoma, Islet Cell; Alkaline Phosphatase; Bicarbonates; Calcium; Creatinine; Diarrhea; Humans; Hype

1967
[Disorders of water-electrolyte metabolism associated with decompensated cirrhosis. The danger of various therapeutic drugs].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1968, May-14, Volume: 44, Issue:23

    Topics: Acute Kidney Injury; Adult; Aged; Ascites; Blood Transfusion; Blood Urea Nitrogen; Blood Volume Dete

1968
Modern concepts in diuretic therapy.
    Postgraduate medicine, 1974, Volume: 56, Issue:5

    Topics: Blood Volume; Creatinine; Diuretics; Drug Therapy, Combination; Humans; Hyperaldosteronism; Hyperten

1974
[Severe hypopotassemia in patients with ureterosigmoid anastomosis].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1972, Oct-30, Volume: 92, Issue:30

    Topics: Acidosis; Adult; Bicarbonates; Colon; Colon, Sigmoid; Diuresis; Electrocardiography; Female; Humans;

1972
Potassium deficiency during treatment with Brinaldix K.
    British medical journal, 1973, Jul-07, Volume: 3, Issue:5870

    Topics: Aged; Chlorides; Clopamide; Female; Humans; Hypokalemia; Middle Aged; Potassium; Potassium Deficienc

1973
Electrolyte disturbances in Liberian children with kwashiorkor.
    The Journal of pediatrics, 1973, Volume: 83, Issue:5

    Topics: Alkalies; Alkalosis; Arteries; Blood; Calcium; Child; Child, Preschool; Chlorides; Chloroquine; Cult

1973
Laxative-induced diarrhoea: a continuing clinical problem.
    British medical journal, 1974, Mar-23, Volume: 1, Issue:5907

    Topics: Abdomen; Adult; Aged; Bicarbonates; Body Weight; Cathartics; Colon; Diarrhea; Feces; Female; Humans;

1974
[Hematological, blood biochemical and certain clinical aspects of tuberculosis in the Bantu].
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1974, Aug-03, Volume: 48, Issue:37

    Topics: Adult; Black or African American; Black People; Blood Protein Electrophoresis; Blood Proteins; Blood

1974
Duogastrone-induced hypokalaemic nephropathy and myopathy with myoglobinuria.
    Postgraduate medical journal, 1971, Volume: 47, Issue:554

    Topics: Carbon Dioxide; Creatinine; Glycyrrhiza; Humans; Hypokalemia; Kidney Diseases; Male; Middle Aged; Mu

1971
Hypokalaemic myopathy and myoglobinuria due to carbenoxolone sodium.
    Postgraduate medical journal, 1971, Volume: 47, Issue:554

    Topics: Aged; Bicarbonates; Chlorides; Glycyrrhiza; Humans; Hypokalemia; Male; Muscular Diseases; Myoglobinu

1971
Treatment with capreomycin, with special reference to toxic effects.
    Tubercle, 1969, Volume: 50

    Topics: Adult; Aged; Alkalosis; Anti-Bacterial Agents; Antitubercular Agents; Creatinine; Female; Hearing Di

1969
[Disorders of the extra- and intracellular water and electrolyte household in delirium tremens].
    Deutsche medizinische Wochenschrift (1946), 1971, Feb-19, Volume: 96, Issue:8

    Topics: Acidosis; Blood Urea Nitrogen; Dehydration; Erythrocytes; Extracellular Space; Humans; Hypokalemia;

1971
High dose frusemide in the treatment of hypertension in chronic renal insufficiency and of terminal renal failure.
    Postgraduate medical journal, 1971, Volume: 47

    Topics: Adolescent; Adult; Creatine; Creatinine; Diuresis; Female; Furosemide; Gout; Humans; Hypertension, R

1971
Effect of cardiopulmonary bypass and haemodilution on some constituents of blood.
    Canadian Anaesthetists' Society journal, 1965, Volume: 12, Issue:5

    Topics: Adolescent; Adult; Blood; Blood Glucose; Blood Proteins; Child; Child, Preschool; Female; Heart-Lung

1965