Page last updated: 2024-10-20

urea and Hypertension, Malignant

urea has been researched along with Hypertension, Malignant in 26 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Hypertension, Malignant: A condition of markedly elevated BLOOD PRESSURE with DIASTOLIC PRESSURE usually greater than 120 mm Hg. Malignant hypertension is characterized by widespread vascular damage, PAPILLEDEMA, retinopathy, HYPERTENSIVE ENCEPHALOPATHY, and renal dysfunction.

Research Excerpts

ExcerptRelevanceReference
"Although it has been reported that the circulating adrenomedullin (AM) level is elevated in hypertension and renal failure, the pathophysiological significance of circulating and intrarenal AM in malignant hypertension remains unknown."7.71Role of increased circulating and renal adrenomedullin in rats with malignant hypertension. ( Horio, T; Kanazawa, A; Kangawa, K; Matsuo, H; Matsuoka, H; Nagaya, N; Nishikimi, T; Okano, I; Yoshihara, F; Yutani, C, 2001)
"Treatment with intravenous and oral diazoxide was given to a group of 39 patients suffering from severe drug-resistant hypertension associated with renal impairment."7.65Use of diazoxide in hypertension with renal failure. ( Pohl, JE; Thurston, H, 1971)
"Although it has been reported that the circulating adrenomedullin (AM) level is elevated in hypertension and renal failure, the pathophysiological significance of circulating and intrarenal AM in malignant hypertension remains unknown."3.71Role of increased circulating and renal adrenomedullin in rats with malignant hypertension. ( Horio, T; Kanazawa, A; Kangawa, K; Matsuo, H; Matsuoka, H; Nagaya, N; Nishikimi, T; Okano, I; Yoshihara, F; Yutani, C, 2001)
" During the fourth to seventh week after the start of the experiment, malignant hypertension developed in most of the animals: body weight fell, reflecting volume depletion; serum osmolality and serum sodium and urea concentrations increased; in the kidneys malignant nephrosclerosis occurred."3.65Is vasopressin involved in the pathogenesis of malignant desoxycorticosterone hypertension in rats? ( Haack, D; Möhring, B; Möhring, J; Petri, M, 1976)
"During the onset of malignant hypertension (MH) in rats treated with deoxycorticosterone trimethylacetate (DOC), plasma arginine vasopressin (AVP) concentrations increase tenfold as a consequence of hypovolemia and hyperosmolality."3.65Vasopressor role of ADH in the pathogenesis of malignant DOC hypertension. ( Haack, D; Möhring, B; Möhring, J; Petri, M, 1977)
"Treatment with intravenous and oral diazoxide was given to a group of 39 patients suffering from severe drug-resistant hypertension associated with renal impairment."3.65Use of diazoxide in hypertension with renal failure. ( Pohl, JE; Thurston, H, 1971)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199024 (92.31)18.7374
1990's0 (0.00)18.2507
2000's2 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
ZOSIN, C1
MANESCU, N1
SCHWARTZKOPF, A1
CLAURE, H1
GARCIA, H1
ACCHIARDO, S1
Gibson, DG1
Kazda, S1
Garthoff, B1
Dycka, J1
Iwai, J1
Lip, GY1
Beevers, M1
Beevers, DG2
Nishikimi, T1
Yoshihara, F1
Kanazawa, A1
Okano, I1
Horio, T1
Nagaya, N1
Yutani, C1
Matsuo, H1
Matsuoka, H1
Kangawa, K1
Möhring, J2
Möhring, B2
Petri, M2
Haack, D2
Calich, NJ1
dos Santos, MV1
Prompt, CA1
Costa, C1
Franco, RJ1
Matsubara, LS1
Bonilha, JP1
Mota, AC1
Soares, VA1
Habermann, F1
Almeida, DB1
Pogglitsch, H1
Waller, J1
Pristautz, H1
Katschnigg, H1
Garner, A1
Ashton, N1
Tripathi, R1
Kohner, EM1
Bulpitt, CJ1
Dollery, CT1
Brown, JJ2
Ferriss, JB1
Fraser, R1
Lever, AF2
Robertson, JI2
Tree, M1
Leary, WP1
Asmal, AC1
Naets, JP1
Wittek, M1
Williams, DM1
Wimpenny, J1
Asscher, AW1
Genest, J1
Boucher, R1
Kuchel, O1
Nowaczynski, W1
Ferrario, CM1
McCubbin, JW1
Peart, WS1
Olbing, H1
Greifer, I1
Bennett, BP1
Bernstein, J1
Spitzer, A1
Wilkinson, JH1
Pohl, JE1
Thurston, H1
Nolph, KD1
Stoltz, ML1
Maher, JF1
Gavras, H1
Brown, WC1
Linton, AL1
MacAdam, RF1
McNicol, GP1
Wardrop, C1
Berlyne, GM1
Gaan, D1
Ginks, WR1
Moyer, JH1
Brest, AN1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Assessment of The Prevalence of Primary Aldosteronism in Hypertensive Patients Presenting With Atrial Flutter or Fibrillation[NCT01267747]411 participants (Actual)Observational2015-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for urea and Hypertension, Malignant

ArticleYear
Diagnostic significance of enzyme determinations in urine.
    Current problems in clinical biochemistry, 1968, Volume: 2, Issue:0

    Topics: Acute Disease; Alkaline Phosphatase; Chronic Disease; Clinical Enzyme Tests; Cysts; Diabetes Mellitu

1968

Other Studies

25 other studies available for urea and Hypertension, Malignant

ArticleYear
[MALIGNANT ARTERIAL HYPERTENSION SYNDROME AND PYELONEPHRITIS].
    Medicina interna, 1963, Volume: 15

    Topics: Anti-Bacterial Agents; Antihypertensive Agents; Blood Chemical Analysis; Humans; Hypertension; Hyper

1963
[EVOLUTION OF CHRONIC NEPHROPATHS WITH SEVERE OR MALIGNANT HYPERTENSION UNDER TREATMENT WITH GUANETHIDINE SULPHATE].
    Revista medica de Chile, 1963, Volume: 91

    Topics: Adolescent; Cerebral Hemorrhage; Guanethidine; Hypertension; Hypertension, Malignant; Hypertension,

1963
Abnormal splitting of the second heart sound in renal failure.
    British medical journal, 1967, Oct-28, Volume: 4, Issue:5572

    Topics: Adult; Bicarbonates; Blood Pressure; Glomerulonephritis; Heart; Hemoglobinometry; Humans; Hypertensi

1967
Prevention of malignant hypertension in salt loaded "S" Dahl rats with the calcium antagonist nifedipine.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:7

    Topics: Animals; Blood Pressure; Creatinine; Female; Heart; Hypertension, Malignant; Muridae; Nifedipine; Or

1982
Serum urate is associated with baseline renal dysfunction but not survival or deterioration in renal function in malignant phase hypertension.
    Journal of hypertension, 2000, Volume: 18, Issue:1

    Topics: Aged; Aging; Blood Pressure; Cause of Death; Creatinine; Female; Follow-Up Studies; Humans; Hyperten

2000
Role of increased circulating and renal adrenomedullin in rats with malignant hypertension.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2001, Volume: 281, Issue:6

    Topics: Adrenomedullin; Animals; Blood Pressure; Blotting, Northern; Body Weight; Calcitonin Receptor-Like P

2001
Is vasopressin involved in the pathogenesis of malignant desoxycorticosterone hypertension in rats?
    Lancet (London, England), 1976, Jan-24, Volume: 1, Issue:7952

    Topics: Angiotensin II; Animals; Antibodies; Arginine Vasopressin; Blood Pressure; Body Weight; Desoxycortic

1976
[Malignant hypertension. Critical analysis of the treatment and prognosis in 18 cases].
    AMB : revista da Associacao Medica Brasileira, 1979, Volume: 25, Issue:8

    Topics: Adult; Creatinine; Female; Humans; Hypertension, Malignant; Male; Middle Aged; Prognosis; Urea

1979
[Malignant hypertension: clinical picture, treatment and evolution of 26 patients].
    Arquivos brasileiros de cardiologia, 1978, Volume: 31, Issue:1

    Topics: Adolescent; Adult; Antihypertensive Agents; Creatinine; Diuretics; Drug Therapy, Combination; Female

1978
[Hemofiltration. Experiences with a new alternative treatment in terminal kidney failure].
    Wiener medizinische Wochenschrift (1946), 1978, Volume: 128, Issue:21

    Topics: Acid-Base Equilibrium; Cholesterol; Electrolytes; Humans; Hypertension, Malignant; Insulin; Insulin

1978
Pathogenesis of hypertensive retinopathy. An experimental study in the monkey.
    The British journal of ophthalmology, 1975, Volume: 59, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Basement Membrane; Blood Flow Velocity; Blood Pressure; Capill

1975
Vasopressor role of ADH in the pathogenesis of malignant DOC hypertension.
    The American journal of physiology, 1977, Volume: 232, Issue:3

    Topics: Angiotensin II; Animals; Antibodies; Arginine Vasopressin; Blood Pressure; Body Weight; Desoxycortic

1977
Renal abnormalities and vascular complications in primary hyperaldosteronism. Evidence on tertiary hyperaldosteronism.
    The Quarterly journal of medicine, 1976, Volume: 45, Issue:179

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aged; Female; Humans; Hyperaldosteronism; Hypertension, Mal

1976
Plasma renin levels in Zulu hypertensives.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975, Apr-12, Volume: 49, Issue:16

    Topics: Black or African American; Black People; Female; Humans; Hypertension; Hypertension, Malignant; Hype

1975
Erythropoiesis in anephric man.
    Lancet (London, England), 1968, May-04, Volume: 1, Issue:7549

    Topics: Acute Disease; Adult; Anuria; Blood Cell Count; Blood Transfusion; Bone Marrow Examination; Erythrop

1968
Renal clearance of sodium sulphadimidine in normal and uraemic subjects.
    Lancet (London, England), 1968, Nov-16, Volume: 2, Issue:7577

    Topics: Adolescent; Adult; Chronic Disease; Diuresis; Female; Glomerular Filtration Rate; Glomerulonephritis

1968
Renin in hypertension: how important as a risk factor?
    Canadian Medical Association journal, 1973, Sep-15, Volume: 109, Issue:6

    Topics: Adult; Angiotensin II; Aortic Aneurysm; Aortic Rupture; Blood Pressure; Cerebrovascular Disorders; C

1973
The unresolved nature of malignant hypertension.
    Acta physiologica latino americana, 1974, Volume: 24, Issue:5

    Topics: Animals; Cardiac Output; Creatinine; Dogs; Hypertension, Malignant; Hypertension, Renal; Nitrogen; P

1974
Results of medical versus surgical treatment of renovascular hypertension.
    Clinical science and molecular medicine. Supplement, 1973, Volume: 45 Suppl 1

    Topics: Adult; Age Factors; Creatinine; Female; Humans; Hypertension, Malignant; Hypertension, Renal; Male;

1973
Idiopathic membranous nephropathy in children.
    Kidney international, 1973, Volume: 3, Issue:6

    Topics: Adolescent; Age Factors; Aminohippuric Acids; Basement Membrane; Biopsy; Child; Child, Preschool; Cr

1973
Use of diazoxide in hypertension with renal failure.
    British medical journal, 1971, Oct-16, Volume: 4, Issue:5780

    Topics: Adolescent; Adult; Blood Glucose; Creatine; Diazoxide; Dietary Proteins; Female; Humans; Hyperglycem

1971
Altered peritoneal permeability in patients with systemic vasculitis.
    Annals of internal medicine, 1971, Volume: 75, Issue:5

    Topics: Capillary Permeability; Creatinine; Diabetic Angiopathies; Diffusion; Epithelium; Humans; Hypertensi

1971
Microangipathic hemolytic anemia and the development of the malignant phase of hypertension.
    Circulation research, 1971, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Anemia, Hemolytic; Blood Coagulation Disorders; Blood Pressure; Child, Preschool;

1971
Dietary treatment of chronic renal failure.
    The American journal of clinical nutrition, 1968, Volume: 21, Issue:6

    Topics: Acidosis; Creatinine; Diet Therapy; Dietary Proteins; Glomerular Filtration Rate; Glomerulonephritis

1968
The changing outlook for the patient with hypertension.
    The American journal of cardiology, 1966, Volume: 17, Issue:5

    Topics: Antihypertensive Agents; Blood Urea Nitrogen; Humans; Hypertension; Hypertension, Malignant; Hyperte

1966