urea has been researched along with Hypercholesterolemia in 33 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Hypercholesterolemia: A condition with abnormally high levels of CHOLESTEROL in the blood. It is defined as a cholesterol value exceeding the 95th percentile for the population.
| Excerpt | Relevance | Reference |
|---|---|---|
| " On the other hand, the supplementation of methionine and threonine to a nonprotein diet ameliorated the body weight loss and decreased the urinary urea excretion in rats." | 7.67 | Effect of methionine and threonine on the hypercholesterolemia induced by polychlorinated biphenyls in rats fed a nonprotein diet. ( Hitomi, Y; Yoshida, A, 1989) |
| "Plasma l-lactic acid could be used as a sensitive biomarker for hypercholesterolemia." | 4.02 | Reconstruction and analysis of correlation networks based on GC-MS metabolomics data for hypercholesterolemia. ( Chen, M; Hou, GF; Jin, YX; OuYang, YN; Tian, Z; Yang, PF; Zhou, LX, 2021) |
| " Diabetes mellitus and hypercholesterolemia were induced with streptozotocin (STZ) and tyloxapol, respectively." | 3.81 | The Antidiabetic and Antihypercholesterolemic Effects of an Aqueous Extract from Pecan Shells in Wistar Rats. ( da Silva, J; Ethur, EM; Ferraz, AB; Marroni, NP; Picada, JN; Porto, CD; Porto, LC, 2015) |
| "Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) shows diverse metabolic abnormalities such as urea cycle dysfunction together with citrullinemia, galactosemia, and suppressed gluconeogenesis." | 3.75 | Sustaining hypercitrullinemia, hypercholesterolemia and augmented oxidative stress in Japanese children with aspartate/glutamate carrier isoform 2-citrin-deficiency even during the silent period. ( Hirano, K; Kobayashi, K; Miida, T; Momoi, T; Nagasaka, H; Ohura, T; Okano, Y; Saheki, T; Shigematsu, Y; Takayanagi, M; Tsukahara, H; Yorifuji, J; Yorifuji, T, 2009) |
| " On the other hand, the supplementation of methionine and threonine to a nonprotein diet ameliorated the body weight loss and decreased the urinary urea excretion in rats." | 3.67 | Effect of methionine and threonine on the hypercholesterolemia induced by polychlorinated biphenyls in rats fed a nonprotein diet. ( Hitomi, Y; Yoshida, A, 1989) |
| "4." | 2.69 | Levels of lactic acid, normal level & its relation to food, glucose, cholesterol, raised blood urea and phenformin therapy. ( Amin, BM; Patel, JC; Sawant, MS, 2000) |
| "Hypertension was induced by L-N(G)-nitroarginine methyl ester (L-NAME) and hypercholesterolemia was induced by feeding rats with a diet containing 1% cholesterol." | 1.46 | Protective effect of the standardized extract of ginkgo biloba (EGb761) against hypertension with hypercholesterolemia-induced renal injury in rats: Insights in the underlying mechanisms. ( Abd-Eldayem, AM; Abdel-Zaher, AO; El-Refaiy, AEM; Farghaly, HSM, 2017) |
| "In experimental CRF hypercholesterolemia has been found to be the main lipid disorder." | 1.31 | Diurnal rhythm of cholesterol biosynthesis in experimental chronic renal failure. ( Boguslawski, W; Chmielewski, M; Nieweglowski, T; Rutkowski, B; Swierczynski, J, 2001) |
| " Tetrazole urea 2i dosed at 3 mg/kg lowered plasma total cholesterol (TC) 67% in an acute, cholesterol-fed (C-fed) rat model of hypercholesterolemia and 47% in C-fed dogs." | 1.29 | Heterocyclic ureas: inhibitors of acyl-CoA:cholesterol O-acyltransferase as hypocholesterolemic agents. ( Blankley, CJ; Bousley, RF; Chucholowski, AW; Creswell, MW; Dominick, MA; Essenburg, AD; Hamelehle, KL; Krause, BR; Neub, M; Stanfield, RL; White, AD; Wilson, MW, 1996) |
| " To test this question, we gave rhGH for 14 days at a dosage of 3 units/day intraperitoneally to two-stage, 5/6 nephrectomized, male Sprague-Dawley rats (n = 18) compared to sex- and age-matched control (n = 27) and CRI (n = 40) rats." | 1.28 | Hypercholesterolemia in rats with chronic renal insufficiency not aggravated by recombinant human growth hormone. ( Chan, JC; Foreman, JW; Hanna, JD; Krieg, RJ; Niimi, K; Perkins, AH; Santos, F, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (24.24) | 18.7374 |
| 1990's | 9 (27.27) | 18.2507 |
| 2000's | 8 (24.24) | 29.6817 |
| 2010's | 7 (21.21) | 24.3611 |
| 2020's | 1 (3.03) | 2.80 |
| Authors | Studies |
|---|---|
| OuYang, YN | 1 |
| Zhou, LX | 1 |
| Jin, YX | 1 |
| Hou, GF | 1 |
| Yang, PF | 1 |
| Chen, M | 1 |
| Tian, Z | 1 |
| Abdel-Zaher, AO | 1 |
| Farghaly, HSM | 1 |
| El-Refaiy, AEM | 1 |
| Abd-Eldayem, AM | 1 |
| Leiva, A | 1 |
| de Medina, CD | 1 |
| Salsoso, R | 1 |
| Sáez, T | 1 |
| San Martín, S | 1 |
| Abarzúa, F | 1 |
| Farías, M | 1 |
| Guzmán-Gutiérrez, E | 1 |
| Pardo, F | 1 |
| Sobrevia, L | 1 |
| Porto, LC | 1 |
| da Silva, J | 1 |
| Ferraz, AB | 1 |
| Ethur, EM | 1 |
| Porto, CD | 1 |
| Marroni, NP | 1 |
| Picada, JN | 1 |
| Nagasaka, H | 1 |
| Okano, Y | 1 |
| Tsukahara, H | 1 |
| Shigematsu, Y | 1 |
| Momoi, T | 1 |
| Yorifuji, J | 1 |
| Miida, T | 1 |
| Ohura, T | 1 |
| Kobayashi, K | 1 |
| Saheki, T | 1 |
| Hirano, K | 1 |
| Takayanagi, M | 1 |
| Yorifuji, T | 1 |
| El-Kirsh, AA | 1 |
| Abd El-Wahab, HM | 1 |
| Abd-Ellah Sayed, HF | 1 |
| Balarini, CM | 1 |
| Oliveira, MZ | 1 |
| Pereira, TM | 1 |
| Silva, NF | 1 |
| Vasquez, EC | 1 |
| Meyrelles, SS | 1 |
| Gava, AL | 1 |
| Millán-Calenti, JC | 1 |
| Sánchez, A | 1 |
| Lorenzo-López, L | 1 |
| Maseda, A | 1 |
| Moreira, EL | 1 |
| de Oliveira, J | 1 |
| Dutra, MF | 1 |
| Santos, DB | 1 |
| Gonçalves, CA | 1 |
| Goldfeder, EM | 1 |
| de Bem, AF | 1 |
| Prediger, RD | 1 |
| Aschner, M | 1 |
| Farina, M | 1 |
| WEISS, HS | 1 |
| SCHOENFELD, MR | 1 |
| GOLDBERGER, E | 1 |
| KREPLER, P | 1 |
| BREITFELLNER, G | 1 |
| ZEITLHOFER, J | 1 |
| GHERONDACHE, CN | 1 |
| PINCUS, G | 1 |
| Ban, H | 1 |
| Muraoka, M | 1 |
| Ioriya, K | 1 |
| Ohashi, N | 1 |
| Behall, KM | 1 |
| Scholfield, DJ | 1 |
| Hallfrisch, J | 1 |
| Mittal, G | 1 |
| Vadhera, S | 1 |
| Brar, AP | 1 |
| Soni, G | 1 |
| Zhang, W | 1 |
| Wang, X | 1 |
| Liu, Y | 1 |
| Tian, H | 1 |
| Flickinger, B | 1 |
| Empie, MW | 1 |
| Sun, SZ | 1 |
| Thampy, KG | 1 |
| Subang, MC | 1 |
| Stewart-Phillips, JL | 1 |
| Pappu, AS | 1 |
| Subang, R | 1 |
| Gagnon, RF | 1 |
| Sliskovic, DR | 1 |
| Krause, BR | 3 |
| Picard, JA | 1 |
| Anderson, M | 1 |
| Bousley, RF | 2 |
| Hamelehle, KL | 3 |
| Homan, R | 1 |
| Julian, TN | 1 |
| Rashidbaigi, ZA | 1 |
| Stanfield, RL | 3 |
| Abdel-Gayoum, AA | 1 |
| Bashir, AA | 1 |
| el-Fakhri, MM | 1 |
| White, AD | 1 |
| Creswell, MW | 1 |
| Chucholowski, AW | 1 |
| Blankley, CJ | 1 |
| Wilson, MW | 1 |
| Essenburg, AD | 2 |
| Dominick, MA | 1 |
| Neub, M | 1 |
| Purchase, TS | 1 |
| Hes, MS | 1 |
| Holmes, A | 1 |
| Trivedi, BK | 1 |
| Segawa, K | 1 |
| Kataoka, T | 1 |
| Fukuo, Y | 1 |
| Kacso, I | 1 |
| Gherman, M | 1 |
| Mazouz, H | 1 |
| Ghazali, A | 1 |
| el Esper, N | 1 |
| Morinière, P | 1 |
| Makdassi, R | 1 |
| Hardy, P | 1 |
| Westeel, PF | 1 |
| Achard, JM | 1 |
| Pruna, A | 1 |
| Fournier, A | 1 |
| Ogawa, T | 1 |
| Sugidachi, A | 1 |
| Naganuma, H | 1 |
| Asai, F | 1 |
| Patel, JC | 1 |
| Sawant, MS | 1 |
| Amin, BM | 1 |
| Chmielewski, M | 1 |
| Nieweglowski, T | 1 |
| Swierczynski, J | 1 |
| Rutkowski, B | 1 |
| Boguslawski, W | 1 |
| Leonard, JV | 1 |
| Clayton, BE | 1 |
| Colley, JR | 1 |
| Santos, F | 1 |
| Chan, JC | 1 |
| Krieg, RJ | 1 |
| Niimi, K | 1 |
| Hanna, JD | 1 |
| Foreman, JW | 1 |
| Perkins, AH | 1 |
| Hitomi, Y | 1 |
| Yoshida, A | 1 |
| Bailey, A | 1 |
| Förster, H | 1 |
| Heller, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Healthy Effects of an Innovative Probiotic Pasta[NCT02236533] | 40 participants (Actual) | Interventional | 2014-03-31 | Completed | |||
| A Dose Response, Randomized, Controlled, Double-blind, Cross-over Trial to Determine the LDL Cholesterol Lowering Effect of Ground Flaxseed in Adults With Above Optimal Plasma LDL Concentrations[NCT01821131] | 76 participants (Anticipated) | Interventional | 2014-01-31 | Active, not recruiting | |||
| Flaxseed Lignan Enriched Complex for Blood Pressure Reduction in Elderly Participants With High Normal Blood Pressure or Stage I Hypertension[NCT02391779] | Phase 2 | 100 participants (Anticipated) | Interventional | 2015-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for urea and Hypercholesterolemia
| Article | Year |
|---|---|
[Factors in the progression of renal insufficiency during the 2 years preceding the use of dialysis].
Topics: Acidosis; Aged; Anemia; Antihypertensive Agents; Blood Proteins; Combined Modality Therapy; Comorbid | 1999 |
6 trials available for urea and Hypercholesterolemia
| Article | Year |
|---|---|
Whole-grain diets reduce blood pressure in mildly hypercholesterolemic men and women.
Topics: Adult; Blood Pressure; Body Weight; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Cholesterol | 2006 |
Dietary flaxseed lignan extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects.
Topics: Adult; Alanine Transaminase; Blood Glucose; Butylene Glycols; Cholesterol; Cholesterol, HDL; Cholest | 2008 |
Dietary flaxseed lignan extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects.
Topics: Adult; Alanine Transaminase; Blood Glucose; Butylene Glycols; Cholesterol; Cholesterol, HDL; Cholest | 2008 |
Dietary flaxseed lignan extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects.
Topics: Adult; Alanine Transaminase; Blood Glucose; Butylene Glycols; Cholesterol; Cholesterol, HDL; Cholest | 2008 |
Dietary flaxseed lignan extract lowers plasma cholesterol and glucose concentrations in hypercholesterolaemic subjects.
Topics: Adult; Alanine Transaminase; Blood Glucose; Butylene Glycols; Cholesterol; Cholesterol, HDL; Cholest | 2008 |
Cholesterol-lowering effects of psyllium seed associated with urea metabolism.
Topics: Adult; Cholesterol; Female; Humans; Hypercholesterolemia; Male; Middle Aged; Psyllium; Retrospective | 1998 |
Levels of lactic acid, normal level & its relation to food, glucose, cholesterol, raised blood urea and phenformin therapy.
Topics: Diabetes Mellitus, Type 2; Diet; Female; Humans; Hypercholesterolemia; Hyperglycemia; India; Lactic | 2000 |
Use of biochemical profile in children's hospital: results of two controlled trials.
Topics: Alkaline Phosphatase; Anemia; Aspartate Aminotransferases; Biopsy; Blood Glucose; Blood Proteins; Ca | 1975 |
[Studies on the significance of carbohydrates in a fully synthetic fat-free diet].
Topics: Adult; Cholesterol; Creatinine; Dietary Carbohydrates; Female; Fructose; Humans; Hypercholesterolemi | 1973 |
26 other studies available for urea and Hypercholesterolemia
| Article | Year |
|---|---|
Reconstruction and analysis of correlation networks based on GC-MS metabolomics data for hypercholesterolemia.
Topics: Adolescent; Adult; Arginine; Biomarkers; Case-Control Studies; Cholesterol; Cysteine; Female; Gas Ch | 2021 |
Protective effect of the standardized extract of ginkgo biloba (EGb761) against hypertension with hypercholesterolemia-induced renal injury in rats: Insights in the underlying mechanisms.
Topics: Animals; Blood Pressure; Creatinine; Diastole; Ginkgo biloba; Glutathione; Hypercholesterolemia; Hyp | 2017 |
Maternal hypercholesterolemia in pregnancy associates with umbilical vein endothelial dysfunction: role of endothelial nitric oxide synthase and arginase II.
Topics: Adult; Arginase; Cationic Amino Acid Transporter 1; Cationic Amino Acid Transporter 2; Cells, Cultur | 2013 |
The Antidiabetic and Antihypercholesterolemic Effects of an Aqueous Extract from Pecan Shells in Wistar Rats.
Topics: Animals; Anticholesteremic Agents; Blood Glucose; Carya; Cholesterol; Diabetes Mellitus, Experimenta | 2015 |
Sustaining hypercitrullinemia, hypercholesterolemia and augmented oxidative stress in Japanese children with aspartate/glutamate carrier isoform 2-citrin-deficiency even during the silent period.
Topics: Amino Acids; Apolipoproteins; Asian People; Biomarkers; Carbohydrates; Child; Child, Preschool; Citr | 2009 |
The effect of L-arginine or L-citrulline supplementation on biochemical parameters and the vascular aortic wall in high-fat and high-cholesterol-fed rats.
Topics: Administration, Oral; Alanine Transaminase; Animals; Anticholesteremic Agents; Antioxidants; Aorta; | 2011 |
Hypercholesterolemia promotes early renal dysfunction in apolipoprotein E-deficient mice.
Topics: Age Factors; Animals; Apolipoproteins E; Fibrosis; Gene Expression; Glomerular Filtration Rate; Hype | 2011 |
Laboratory values in a Spanish population of older adults: a comparison with reference values from younger adults.
Topics: Age Factors; Aged; Aged, 80 and over; Biomarkers; Blood Glucose; Cardiovascular Diseases; Cholestero | 2012 |
Does methylmercury-induced hypercholesterolemia play a causal role in its neurotoxicity and cardiovascular disease?
Topics: Animals; Anticholesteremic Agents; Behavior, Animal; Biomarkers; Cardiovascular Diseases; Cerebellum | 2012 |
Nicarbazin induced hypercholesterolemia in the hen.
Topics: Animals; Chickens; Cholesterol; Female; Humans; Hypercholesterolemia; Nicarbazin; Pyrimidines; Urea | 1960 |
HYPERCHOLESTEROLEMIA INDUCED BY THIAZIDES: A PILOT STUDY.
Topics: Bendroflumethiazide; Biomedical Research; Blood Chemical Analysis; Cholesterol; Diet, Sodium-Restric | 1964 |
[VITAMIN D INTOXICATION AND "IDIOPATHIC HYPERCALCEMIA"].
Topics: Blood Urea Nitrogen; Cholestanes; Diagnosis, Differential; Drug Hypersensitivity; Humans; Hypercalce | 1964 |
METABOLIC CHANGES INDUCED IN ELDERLY PATIENTS WITH A CHOLESTEROL LOWERING RESIN, CHOLESTYRAMINE.
Topics: Aged; Anticholesteremic Agents; Blood Urea Nitrogen; Carbon Dioxide; Cholesterol; Cholestyramine Res | 1964 |
Synthesis and biological activity of novel 4-phenyl-1,8-naphthyridin-2(1H)-on-3-yl ureas: potent acyl-CoA:cholesterol acyltransferase inhibitor with improved aqueous solubility.
Topics: Acyltransferases; Administration, Oral; Anticholesteremic Agents; Drug Design; Enzyme Inhibitors; Hu | 2006 |
Protective role of dietary fibre on N-nitrosopyrrolidine-induced toxicity in hypercholesterolemic rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Cholesterol, Dietary; Cicer; Creatinine; | 2007 |
Hypercholesterolaemia of prolonged fasting and cholesterol lowering of re-feeding in lean human subjects.
Topics: Adult; Bilirubin; Blood Glucose; Cholesterol; Cholesterol Esters; Creatinine; Eating; Enzymes; Fasti | 1995 |
Possible role of mevalonate in the hypercholesterolemia seen in experimental chronic renal failure.
Topics: Animals; Cholesterol; Disease Models, Animal; Female; Hypercholesterolemia; Kidney Failure, Chronic; | 1995 |
Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 6. The first water-soluble ACAT inhibitor with lipid-regulating activity.
Topics: Absorption; Animals; Anticholesteremic Agents; Biological Availability; Carbamates; Cholesterol; Cho | 1994 |
Effects of fish oil and sunflower oil supplementations on gentamicin-induced nephrotoxicity in rat.
Topics: Administration, Oral; Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Cod Liver Oil; Creatinin | 1995 |
Heterocyclic ureas: inhibitors of acyl-CoA:cholesterol O-acyltransferase as hypocholesterolemic agents.
Topics: Animals; Anticholesteremic Agents; Cholesterol, HDL; Chromatography, High Pressure Liquid; Disease M | 1996 |
Inhibitors of acyl-CoA:cholesterol acyltransferase: novel trisubstituted ureas as hypocholesterolemic agents.
Topics: Administration, Oral; Animals; Anticholesteremic Agents; Benzene Derivatives; Cholesterol; Diet; Dis | 1997 |
Antiplatelet and antithrombotic effects of orbofiban, a new orally active GPIIb/IIIa antagonist, in guinea pigs.
Topics: Adenosine Diphosphate; Administration, Oral; Alanine; Animals; Arteriovenous Shunt, Surgical; Aspiri | 2000 |
Diurnal rhythm of cholesterol biosynthesis in experimental chronic renal failure.
Topics: Animals; Body Weight; Cholesterol; Circadian Rhythm; Creatinine; Disease Models, Animal; Hypercholes | 2001 |
Hypercholesterolemia in rats with chronic renal insufficiency not aggravated by recombinant human growth hormone.
Topics: Animals; Blood Glucose; Cholesterol; Creatinine; Growth Hormone; Hypercholesterolemia; Kidney Failur | 1992 |
Effect of methionine and threonine on the hypercholesterolemia induced by polychlorinated biphenyls in rats fed a nonprotein diet.
Topics: Animals; Bile Acids and Salts; Cholesterol; Dietary Proteins; Feces; Hydroxymethylglutaryl CoA Reduc | 1989 |
Biochemistry of well populations.
Topics: Adult; Biochemical Phenomena; Biochemistry; Blood Chemical Analysis; Blood Glucose; Blood Proteins; | 1974 |