urea has been researched along with Hepatocellular Carcinoma in 87 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study is validated the prophylactic efficacy of urea-based creams on sorafenib-induced hand-foot skin reaction in patients with advanced hepatocellular carcinoma." | 9.51 | Validation of the prophylactic efficacy of urea-based creams on sorafenib-induced hand-foot skin reaction in patients with advanced hepatocellular carcinoma: A randomised experiment study. ( Hu, SH; Lien, RY; Lu, LC; Lu, SF; Tung, HH; Wu, SL, 2022) |
| "Hand-foot skin reaction (HFSR) is the most common adverse event during sorafenib treatment in patients with hepatocellular carcinoma (HCC)." | 9.34 | Effect of urea cream on sorafenib-associated hand-foot skin reaction in patients with hepatocellular carcinoma: A multicenter, randomised, double-blind controlled study. ( Cho, SB; Hong, YM; Hwang, SY; Jang, BK; Jang, ES; Jang, JY; Jung, YK; Kim, DY; Kim, HJ; Kim, JH; Kim, MY; Lee, HW; Lee, JH; Lee, YS; Seo, YS; Yim, HJ; Yoon, KT, 2020) |
| "To assess whether urea-based cream (UBC) has prophylactic benefits on sorafenib-induced hand-foot skin reaction (HFSR) in patients with advanced hepatocellular carcinoma (HCC)." | 9.20 | Randomized controlled trial of the prophylactic effect of urea-based cream on sorafenib-associated hand-foot skin reactions in patients with advanced hepatocellular carcinoma. ( Bai, Y; Guo, X; Kang, H; Lu, L; Lu, M; Qu, Z; Ren, Z; Shi, L; Song, T; Wang, H; Wang, X; Yang, W; Yang, Y; Ye, SL; Zhou, W; Zhu, K, 2015) |
| " RESULTS In the mouse model of NAFLD, RKI-1447 reduced insulin resistance and the levels of alanine aminotransferase (ALT), aspartate transaminase (AST), total cholesterol, triglyceride, interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), malondialdehyde (MDA), and superoxide dismutase (SOD)." | 7.96 | The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid. ( Jiang, W; Wang, J, 2020) |
| "In our effort to develop potent and effective agents with anti-proliferative activity towards HepG2 hepatocellular carcinoma cells with potential inhibitory activity against VEGFR-2, a novel series of 1-(4-((2-oxoindolin-3-ylidene)amino)phenyl)-3-arylureas was designed and synthesized." | 7.81 | Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking. ( Abdel-Aziz, HA; Abou El Ella, DA; Abou-Seri, SM; Ali, MM; Aly, MH; Eldehna, WM; Fares, M; Ibrahim, HS; Zada, S, 2015) |
| "The aim of this study is validated the prophylactic efficacy of urea-based creams on sorafenib-induced hand-foot skin reaction in patients with advanced hepatocellular carcinoma." | 5.51 | Validation of the prophylactic efficacy of urea-based creams on sorafenib-induced hand-foot skin reaction in patients with advanced hepatocellular carcinoma: A randomised experiment study. ( Hu, SH; Lien, RY; Lu, LC; Lu, SF; Tung, HH; Wu, SL, 2022) |
| "In this report, we show that human hepatocellular carcinoma (HCC) cells do not express CPS1, whereas cultured human primary hepatocytes express abundant levels." | 5.37 | DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma. ( Dong, H; Liu, C; Liu, H; Robertson, K, 2011) |
| "Hand-foot skin reaction (HFSR) is the most common adverse event during sorafenib treatment in patients with hepatocellular carcinoma (HCC)." | 5.34 | Effect of urea cream on sorafenib-associated hand-foot skin reaction in patients with hepatocellular carcinoma: A multicenter, randomised, double-blind controlled study. ( Cho, SB; Hong, YM; Hwang, SY; Jang, BK; Jang, ES; Jang, JY; Jung, YK; Kim, DY; Kim, HJ; Kim, JH; Kim, MY; Lee, HW; Lee, JH; Lee, YS; Seo, YS; Yim, HJ; Yoon, KT, 2020) |
| "To assess whether urea-based cream (UBC) has prophylactic benefits on sorafenib-induced hand-foot skin reaction (HFSR) in patients with advanced hepatocellular carcinoma (HCC)." | 5.20 | Randomized controlled trial of the prophylactic effect of urea-based cream on sorafenib-associated hand-foot skin reactions in patients with advanced hepatocellular carcinoma. ( Bai, Y; Guo, X; Kang, H; Lu, L; Lu, M; Qu, Z; Ren, Z; Shi, L; Song, T; Wang, H; Wang, X; Yang, W; Yang, Y; Ye, SL; Zhou, W; Zhu, K, 2015) |
| " AQP3 is involved in the diarrhea and inflammatory bowel disease; AQP5 is relevant to gastric carcinoma cell proliferation and migration; AQP9 plays considerable role in glycerol metabolism , urea transport and hepatocellular carcinoma." | 4.95 | Aquaporins in Digestive System. ( Mei, Z; Ran, J; Yang, B; Zhu, S, 2017) |
| "We aimed to determine the association between blood urea level and incident cirrhosis, hepatic decompensation, and hepatocellular carcinoma in chronic liver disease (CLD) patients." | 4.12 | U-shaped relationship between urea level and hepatic decompensation in chronic liver diseases. ( Chan, HL; Hui, VW; Lai, JC; Lin, H; Liu, K; Tse, YK; Wong, GL; Wong, VW; Yip, TC; Zhang, X, 2022) |
| " RESULTS In the mouse model of NAFLD, RKI-1447 reduced insulin resistance and the levels of alanine aminotransferase (ALT), aspartate transaminase (AST), total cholesterol, triglyceride, interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), malondialdehyde (MDA), and superoxide dismutase (SOD)." | 3.96 | The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid. ( Jiang, W; Wang, J, 2020) |
| " Among these analogues, 3y exhibited a better cytotoxic effect on human hepatocellular carcinoma (HCC) Hep 3B cells and displayed less cytotoxicity on normal human umbilical vein endothelial cells, compared with Sorafenib, a targeted therapy for advanced HCC." | 3.85 | Using gene expression database to uncover biology functions of 1,4-disubstituted 1,2,3-triazole analogues synthesized via a copper (I)-catalyzed reaction. ( Huang, CF; Liu, HS; Ramesh, C; Su, CL; Tseng, CL; Yao, CF, 2017) |
| "In our effort to develop potent and effective agents with anti-proliferative activity towards HepG2 hepatocellular carcinoma cells with potential inhibitory activity against VEGFR-2, a novel series of 1-(4-((2-oxoindolin-3-ylidene)amino)phenyl)-3-arylureas was designed and synthesized." | 3.81 | Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking. ( Abdel-Aziz, HA; Abou El Ella, DA; Abou-Seri, SM; Ali, MM; Aly, MH; Eldehna, WM; Fares, M; Ibrahim, HS; Zada, S, 2015) |
| " Here, we report the effect of an APN inhibitor 4cc in enhancing sensitivity of hepatocellular carcinoma (HCC) cell lines and xenograft model in response to 5-fluorouracil (5-FU) in vivo and in vitro." | 3.81 | Aminopeptidase N inhibitor 4cc synergizes antitumor effects of 5-fluorouracil on human liver cancer cells through ROS-dependent CD13 inhibition. ( Dai, G; Duan, Y; Shi, LH; Sun, ZP; Wang, XJ; Xu, WF; Zhang, J; Zhang, XR, 2015) |
| "The rates of urea synthesis in rat liver and in a series of rat liver neoplasms with widely different growth rates and degree of differentiation were investigated using tissue slices incubated in a Krebs-Ringer bicarbonate buffer." | 3.65 | Urea synthesis in Novikoff and Morris hepatomas. ( Lawson, D; Morris, HP; Paik, WK; Weinhouse, S, 1977) |
| "The purpose of this Functional Imaging Liver Cancer (FLIC) trial is to assess the ability of 18F-DCFPyL-PET/CT to detect sites of HCC." | 3.11 | Functional Imaging of Liver Cancer (FLIC): Study protocol of a phase 2 trial of 18F-DCFPyL PET/CT imaging for patients with hepatocellular carcinoma. ( Choyke, PL; Chung, JY; Escorcia, FE; Hernandez, J; Jakhete, N; Jones, J; Kassin, M; Lindenberg, L; Maass-Moreno, R; Mena, E; Molitoris, JK; Monge, C; Rabiee, A; Saboury, B; Salerno, KE; Shih, J; Turkbey, B; Unger, KR; Wood, B, 2022) |
| "HepG2 is a human hepatoma that is most commonly used in drug metabolism and hepatotoxicity studies." | 1.42 | Culture and Functional Characterization of Human Hepatoma HepG2 Cells. ( Donato, MT; Gómez-Lechón, MJ; Tolosa, L, 2015) |
| "In this report, we show that human hepatocellular carcinoma (HCC) cells do not express CPS1, whereas cultured human primary hepatocytes express abundant levels." | 1.37 | DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma. ( Dong, H; Liu, C; Liu, H; Robertson, K, 2011) |
| "Urea was quantified using (15)N-ammonium chloride metabolic labelling with gas chromatography-mass spectrometry." | 1.35 | Cells for bioartificial liver devices: the human hepatoma-derived cell line C3A produces urea but does not detoxify ammonia. ( Damelin, LH; Eaton, S; Hodgson, HJ; Mavri-Damelin, D; Rees, M; Selden, C, 2008) |
| "01), at least compatible to the inhibition by vincristine (43% inhibition), indicating good bioavailability of the compound in the circulation." | 1.32 | Inhibition of microtubule polymerization by 3-bromopropionylamino benzoylurea (JIMB01), a new cancericidal tubulin ligand. ( Bekesi, G; Holland, JF; Hu, QY; Jiang, JD; Li, JN; Lin, YH; Song, DQ; Yin, L, 2003) |
| "In fact, the hepatomas showed the greatest changes in response to diet." | 1.26 | Regulation of urea cycle enzymes in transplantable hepatomas and in the livers of tumor-bearing rats and humans. ( Balinsky, JB; Brebnor, LD; Grimm, J, 1981) |
| "Faster growing hepatomas also have greater quantities of sulfhydryls and disulfides." | 1.25 | Sulfhydryl group quantitation of hepatoma and liver microsomal fractions. ( Hochberg, AA; Morris, HP; Stratman, FW; Zahlten, RN, 1975) |
| "Ferritin purified from hepatoma tissue migrated slightly faster than normal human liver ferritin in polyacrylamide gel electrophoresis." | 1.25 | Characterization and subunit analysis of ferritin isolated from normal and malignant human liver. ( Alpert, E, 1975) |
| "In the hepatomas, evidence was obtained for the preexistence of considerable amounts of the smaller, RNase-containing subunits in the cell." | 1.24 | Studies on the function of intracellular ribonucleases. V. Ribonuclease activity in ribosomes and polysomes prepared from rat liver and hepatomas. ( Roth, JS; Utsunomiya, T, 1966) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 43 (49.43) | 18.7374 |
| 1990's | 5 (5.75) | 18.2507 |
| 2000's | 9 (10.34) | 29.6817 |
| 2010's | 17 (19.54) | 24.3611 |
| 2020's | 13 (14.94) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, H | 1 |
| Wong, GL | 1 |
| Zhang, X | 5 |
| Yip, TC | 1 |
| Liu, K | 1 |
| Tse, YK | 1 |
| Hui, VW | 1 |
| Lai, JC | 1 |
| Chan, HL | 1 |
| Wong, VW | 1 |
| Li, J | 9 |
| Shi, C | 1 |
| Shi, J | 1 |
| Song, J | 4 |
| Wang, N | 1 |
| Lien, RY | 1 |
| Tung, HH | 1 |
| Wu, SL | 1 |
| Hu, SH | 1 |
| Lu, LC | 1 |
| Lu, SF | 1 |
| Sugiura, S | 1 |
| Satoh, T | 1 |
| Shin, K | 1 |
| Onuki-Nagasaki, R | 1 |
| Kanamori, T | 1 |
| Mena, E | 1 |
| Shih, J | 1 |
| Chung, JY | 1 |
| Jones, J | 1 |
| Rabiee, A | 1 |
| Monge, C | 1 |
| Turkbey, B | 1 |
| Lindenberg, L | 1 |
| Salerno, KE | 1 |
| Kassin, M | 1 |
| Wood, B | 1 |
| Hernandez, J | 1 |
| Maass-Moreno, R | 1 |
| Saboury, B | 1 |
| Jakhete, N | 1 |
| Molitoris, JK | 1 |
| Unger, KR | 1 |
| Choyke, PL | 1 |
| Escorcia, FE | 1 |
| Zhang, S | 6 |
| Hu, Y | 3 |
| Wu, Z | 3 |
| Zhou, X | 5 |
| Wu, T | 4 |
| Li, P | 4 |
| Lian, Q | 3 |
| Xu, S | 3 |
| Gu, J | 3 |
| Chen, L | 6 |
| Wu, G | 4 |
| Zhang, T | 5 |
| Tang, J | 3 |
| Xue, J | 3 |
| Ivanova, ON | 1 |
| Krasnov, GS | 1 |
| Snezhkina, AV | 1 |
| Kudryavtseva, AV | 1 |
| Fedorov, VS | 1 |
| Zakirova, NF | 1 |
| Golikov, MV | 1 |
| Kochetkov, SN | 1 |
| Bartosch, B | 1 |
| Valuev-Elliston, VT | 1 |
| Ivanov, AV | 1 |
| Wang, J | 5 |
| Jiang, W | 1 |
| Nguépy Keubo, FR | 1 |
| Mboua, PC | 1 |
| Djifack Tadongfack, T | 1 |
| Fokouong Tchoffo, E | 1 |
| Tasson Tatang, C | 1 |
| Ide Zeuna, J | 1 |
| Noupoue, EM | 1 |
| Tsoplifack, CB | 1 |
| Folefack, GO | 1 |
| Kettani, M | 1 |
| Bandelier, P | 1 |
| Huo, J | 1 |
| Li, H | 5 |
| Yu, D | 1 |
| Arulsamy, N | 1 |
| AlAbbad, S | 1 |
| Sardot, T | 1 |
| Lekashvili, O | 1 |
| Decato, D | 1 |
| Lelj, F | 1 |
| Alexander Ross, JB | 1 |
| Rosenberg, E | 1 |
| Nazir, H | 1 |
| Muthuswamy, N | 1 |
| Louis, C | 1 |
| Jose, S | 1 |
| Prakash, J | 1 |
| Buan, MEM | 1 |
| Flox, C | 1 |
| Chavan, S | 1 |
| Shi, X | 1 |
| Kauranen, P | 1 |
| Kallio, T | 1 |
| Maia, G | 1 |
| Tammeveski, K | 1 |
| Lymperopoulos, N | 1 |
| Carcadea, E | 1 |
| Veziroglu, E | 1 |
| Iranzo, A | 1 |
| M Kannan, A | 1 |
| Arunamata, A | 1 |
| Tacy, TA | 1 |
| Kache, S | 1 |
| Mainwaring, RD | 1 |
| Ma, M | 1 |
| Maeda, K | 1 |
| Punn, R | 1 |
| Noguchi, S | 1 |
| Hahn, S | 3 |
| Iwasa, Y | 3 |
| Ling, J | 2 |
| Voccio, JP | 2 |
| Kim, Y | 3 |
| Bascuñán, J | 2 |
| Chu, Y | 1 |
| Tomita, M | 1 |
| Cazorla, M | 1 |
| Herrera, E | 1 |
| Palomeque, E | 1 |
| Saud, N | 1 |
| Hoplock, LB | 1 |
| Lobchuk, MM | 1 |
| Lemoine, J | 1 |
| Li, X | 10 |
| Henson, MA | 1 |
| Unsihuay, D | 1 |
| Qiu, J | 1 |
| Swaroop, S | 1 |
| Nagornov, KO | 1 |
| Kozhinov, AN | 1 |
| Tsybin, YO | 1 |
| Kuang, S | 1 |
| Laskin, J | 1 |
| Zin, NNINM | 1 |
| Mohamad, MN | 1 |
| Roslan, K | 1 |
| Abdul Wafi, S | 1 |
| Abdul Moin, NI | 1 |
| Alias, A | 1 |
| Zakaria, Y | 1 |
| Abu-Bakar, N | 1 |
| Naveed, A | 1 |
| Jilani, K | 1 |
| Siddique, AB | 1 |
| Akbar, M | 1 |
| Riaz, M | 1 |
| Mushtaq, Z | 1 |
| Sikandar, M | 1 |
| Ilyas, S | 1 |
| Bibi, I | 1 |
| Asghar, A | 1 |
| Rasool, G | 1 |
| Irfan, M | 1 |
| Li, XY | 1 |
| Zhao, S | 1 |
| Fan, XH | 1 |
| Chen, KP | 1 |
| Hua, W | 1 |
| Liu, ZM | 1 |
| Xue, XD | 1 |
| Zhou, B | 1 |
| Xing, YL | 1 |
| Chen, MA | 1 |
| Sun, Y | 1 |
| Neradilek, MB | 1 |
| Wu, XT | 1 |
| Zhang, D | 2 |
| Huang, W | 1 |
| Cui, Y | 1 |
| Yang, QQ | 1 |
| Li, HW | 1 |
| Zhao, XQ | 1 |
| Hossein Rashidi, B | 1 |
| Tarafdari, A | 1 |
| Ghazimirsaeed, ST | 1 |
| Shahrokh Tehraninezhad, E | 1 |
| Keikha, F | 1 |
| Eslami, B | 1 |
| Ghazimirsaeed, SM | 1 |
| Jafarabadi, M | 1 |
| Silvani, Y | 1 |
| Lovita, AND | 1 |
| Maharani, A | 1 |
| Wiyasa, IWA | 1 |
| Sujuti, H | 1 |
| Ratnawati, R | 1 |
| Raras, TYM | 1 |
| Lemin, AS | 1 |
| Rahman, MM | 1 |
| Pangarah, CA | 1 |
| Kiyu, A | 1 |
| Zeng, C | 2 |
| Du, H | 1 |
| Lin, D | 1 |
| Jalan, D | 1 |
| Rubagumya, F | 1 |
| Hopman, WM | 1 |
| Vanderpuye, V | 1 |
| Lopes, G | 1 |
| Seruga, B | 1 |
| Booth, CM | 1 |
| Berry, S | 1 |
| Hammad, N | 1 |
| Sajo, EA | 1 |
| Okunade, KS | 1 |
| Olorunfemi, G | 1 |
| Rabiu, KA | 1 |
| Anorlu, RI | 1 |
| Xu, C | 2 |
| Xiang, Y | 1 |
| Xu, X | 1 |
| Zhou, L | 3 |
| Dong, X | 1 |
| Tang, S | 1 |
| Gao, XC | 1 |
| Wei, CH | 1 |
| Zhang, RG | 1 |
| Cai, Q | 1 |
| He, Y | 1 |
| Tong, F | 1 |
| Dong, JH | 1 |
| Dong, XR | 1 |
| Tang, X | 1 |
| Tao, F | 1 |
| Xiang, W | 1 |
| Zhao, Y | 2 |
| Jin, L | 1 |
| Tao, H | 1 |
| Lei, Y | 1 |
| Gan, H | 1 |
| Huang, Y | 1 |
| Chen, Y | 3 |
| Shan, A | 1 |
| Zhao, H | 2 |
| Wu, M | 2 |
| Ma, Q | 1 |
| Zhang, E | 1 |
| Zhang, J | 5 |
| Li, Y | 5 |
| Xue, F | 1 |
| Deng, L | 1 |
| Liu, L | 2 |
| Yan, Z | 2 |
| Wang, Y | 2 |
| Meng, J | 1 |
| Chen, G | 3 |
| Anastassiadou, M | 1 |
| Bernasconi, G | 1 |
| Brancato, A | 1 |
| Carrasco Cabrera, L | 1 |
| Greco, L | 1 |
| Jarrah, S | 1 |
| Kazocina, A | 1 |
| Leuschner, R | 1 |
| Magrans, JO | 1 |
| Miron, I | 1 |
| Nave, S | 1 |
| Pedersen, R | 1 |
| Reich, H | 1 |
| Rojas, A | 1 |
| Sacchi, A | 1 |
| Santos, M | 1 |
| Theobald, A | 1 |
| Vagenende, B | 1 |
| Verani, A | 1 |
| Du, L | 1 |
| Liu, X | 1 |
| Ren, Y | 1 |
| Jiao, Q | 1 |
| Meng, P | 1 |
| Wang, F | 2 |
| Wang, YS | 1 |
| Wang, C | 3 |
| Wang, W | 1 |
| Wang, S | 2 |
| Hou, J | 1 |
| Zhang, A | 2 |
| Lv, B | 1 |
| Gao, C | 1 |
| Pang, D | 1 |
| Lu, K | 1 |
| Ahmad, NH | 1 |
| Wang, L | 1 |
| Zhu, J | 2 |
| Zhang, L | 2 |
| Zhuang, T | 1 |
| Tu, J | 1 |
| Zhao, Z | 1 |
| Qu, Y | 1 |
| Yao, H | 1 |
| Wang, X | 6 |
| Lee, DF | 1 |
| Shen, J | 3 |
| Wen, L | 1 |
| Huang, G | 2 |
| Xie, X | 1 |
| Zhao, Q | 1 |
| Hu, W | 2 |
| Zhang, Y | 4 |
| Wu, X | 1 |
| Lu, J | 2 |
| Li, M | 2 |
| Li, W | 2 |
| Wu, W | 1 |
| Du, F | 1 |
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| Yang, X | 2 |
| Xu, Z | 1 |
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| Su, Q | 1 |
| Huang, H | 1 |
| Wei, Y | 2 |
| Gao, Y | 2 |
| Na, KJ | 1 |
| Choi, H | 1 |
| Oh, HR | 1 |
| Kim, YH | 1 |
| Lee, SB | 1 |
| Jung, YJ | 1 |
| Koh, J | 1 |
| Park, S | 1 |
| Lee, HJ | 1 |
| Jeon, YK | 1 |
| Chung, DH | 1 |
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| Kang, KW | 1 |
| Lee, DS | 1 |
| Kim, YT | 1 |
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| Sainz, B | 1 |
| Perona, R | 1 |
| Sanchez-Perez, I | 1 |
| Logotheti, S | 1 |
| Marquardt, S | 1 |
| Gupta, SK | 1 |
| Richter, C | 1 |
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| Singh, KP | 1 |
| Wolkenhauer, O | 1 |
| Heckl, D | 1 |
| Spitschak, A | 1 |
| Pützer, BM | 1 |
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| Cheng, J | 1 |
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| Li, S | 1 |
| Zhang, M | 4 |
| Zhang, H | 1 |
| Yang, T | 2 |
| Dong, Y | 1 |
| Xu, Y | 1 |
| Yuan, Z | 1 |
| Cao, J | 1 |
| Zheng, Y | 1 |
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| Mei, Z | 2 |
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| Liang, C | 1 |
| Yang, H | 2 |
| Song, Y | 1 |
| Yu, K | 1 |
| Zhu, C | 1 |
| Huang, Z | 1 |
| Qian, J | 1 |
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| Hu, J | 2 |
| Wang, H | 4 |
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| Mi, Y | 1 |
| Kong, H | 1 |
| Xi, D | 1 |
| Yan, W | 1 |
| Luo, X | 1 |
| Ning, Q | 1 |
| Chang, X | 2 |
| Wang, Q | 2 |
| Rathore, MG | 1 |
| Reddy, K | 1 |
| Chen, H | 2 |
| Shin, SH | 1 |
| Ma, WY | 1 |
| Bode, AM | 1 |
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| Gao, F | 1 |
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| Bianconi, V | 1 |
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| Sahebkar, A | 1 |
| Mannarino, MR | 1 |
| Pirro, M | 1 |
| Patsourakos, NG | 1 |
| Kouvari, M | 1 |
| Kotidis, A | 1 |
| Kalantzi, KI | 1 |
| Tsoumani, ME | 1 |
| Anastasiadis, F | 1 |
| Andronikos, P | 1 |
| Aslanidou, T | 1 |
| Efraimidis, P | 1 |
| Georgiopoulos, A | 1 |
| Gerakiou, K | 1 |
| Grigoriadou-Skouta, E | 1 |
| Grigoropoulos, P | 1 |
| Hatzopoulos, D | 1 |
| Kartalis, A | 1 |
| Lyras, A | 1 |
| Markatos, G | 1 |
| Mikrogeorgiou, A | 1 |
| Myroforou, I | 1 |
| Orkopoulos, A | 1 |
| Pavlidis, P | 1 |
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| Skouloudi, M | 1 |
| Smyrnioudis, N | 1 |
| Thomaidis, K | 1 |
| Tsikouri, GE | 1 |
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| Zisimos, K | 1 |
| Vavoulis, P | 1 |
| Vitali, MG | 1 |
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| Chantanis, S | 1 |
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| Panagiotakos, DB | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Re-validating Prophylactic Efficacy of Urea-based Cream on Sorafenib-induced Hand-foot Skin Reaction in Patients With Advanced Hepatocellular Carcinoma[NCT04568330] | 129 participants (Actual) | Interventional | 2014-03-21 | Completed | |||
| 18F-DCFPyL PET/CT in Hepatocellular Carcinoma[NCT05009979] | Phase 2 | 50 participants (Anticipated) | Interventional | 2023-01-18 | Recruiting | ||
| The Effect of Urea Cream on Sorafenib-associated Hand-Foot Skin Reaction in Patients With Korean Hepatocellular Carcinoma Patients: Multicenter, Prospective Randomized Double-Blind Controlled Study[NCT03212625] | Phase 4 | 288 participants (Actual) | Interventional | 2016-01-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for urea and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Aquaporins in Digestive System.
Topics: Animals; Aquaporin 1; Biological Transport; Carcinoma, Hepatocellular; Cell Movement; Cell Prolifera | 2017 |
Use of newborn and infant animals in carcinogenicity testing.
Topics: Age Factors; Animals; Animals, Newborn; Anthracenes; Carcinogens; Carcinoma, Hepatocellular; Hydroca | 1968 |
[Abnormality in ontogeney and phylogeney in cancer cells with special reference to nitrogen metabolism].
Topics: Animals; Biological Evolution; Carcinoma, Hepatocellular; DNA, Neoplasm; Glutaminase; Isoenzymes; Ki | 1971 |
Two carbamyl phosphate synthetases of mammals: specific roles in control of pyrimidine and urea biosynthesis.
Topics: Adenosine Triphosphate; Animals; Arginine; Aspartic Acid; Carbamates; Carbon Isotopes; Carcinoma, He | 1972 |
5 trials available for urea and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Validation of the prophylactic efficacy of urea-based creams on sorafenib-induced hand-foot skin reaction in patients with advanced hepatocellular carcinoma: A randomised experiment study.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Hand-Foot Syndrome; Humans; Liver Neoplasms; Niaci | 2022 |
Functional Imaging of Liver Cancer (FLIC): Study protocol of a phase 2 trial of 18F-DCFPyL PET/CT imaging for patients with hepatocellular carcinoma.
Topics: Carcinoma, Hepatocellular; Clinical Trials, Phase II as Topic; Fluorodeoxyglucose F18; Humans; Liver | 2022 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acryli | 2021 |
Effect of urea cream on sorafenib-associated hand-foot skin reaction in patients with hepatocellular carcinoma: A multicenter, randomised, double-blind controlled study.
Topics: Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Double-Blind Method; Female; Hand-Foot Syndr | 2020 |
Randomized controlled trial of the prophylactic effect of urea-based cream on sorafenib-associated hand-foot skin reactions in patients with advanced hepatocellular carcinoma.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Hepatocel | 2015 |
Randomized controlled trial of the prophylactic effect of urea-based cream on sorafenib-associated hand-foot skin reactions in patients with advanced hepatocellular carcinoma.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Hepatocel | 2015 |
Randomized controlled trial of the prophylactic effect of urea-based cream on sorafenib-associated hand-foot skin reactions in patients with advanced hepatocellular carcinoma.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Hepatocel | 2015 |
Randomized controlled trial of the prophylactic effect of urea-based cream on sorafenib-associated hand-foot skin reactions in patients with advanced hepatocellular carcinoma.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Hepatocel | 2015 |
78 other studies available for urea and Hepatocellular Carcinoma
| Article | Year |
|---|---|
U-shaped relationship between urea level and hepatic decompensation in chronic liver diseases.
Topics: Carcinoma, Hepatocellular; Elasticity Imaging Techniques; Humans; Liver Cirrhosis; Liver Failure; Li | 2022 |
Determination of risk factors for fever after transarterial chemoembolization with drug-eluting beads for hepatocellular carcinoma.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; China | 2021 |
Perfusion culture of multi-layered HepG2 hepatocellular carcinoma cells in a pressure-driven microphysiological system.
Topics: Albumins; Carcinoma, Hepatocellular; Cell Culture Techniques; Hep G2 Cells; Hepatocytes; Humans; Liv | 2022 |
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Carbamyl | 2023 |
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Carbamyl | 2023 |
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Carbamyl | 2023 |
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Carbamyl | 2023 |
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Carbamyl | 2023 |
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Carbamyl | 2023 |
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Carbamyl | 2023 |
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Carbamyl | 2023 |
Deficiency of Carbamoyl Phosphate Synthetase 1 Engenders Radioresistance in Hepatocellular Carcinoma via Deubiquitinating c-Myc.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase I Deficiency Disease; Carbamyl | 2023 |
Transcriptome Analysis of Redox Systems and Polyamine Metabolic Pathway in Hepatoma and Non-Tumor Hepatocyte-like Cells.
Topics: Carcinoma, Hepatocellular; Gene Expression Profiling; Hepatocytes; Humans; Liver Neoplasms; Metaboli | 2023 |
The Effects of RKI-1447 in a Mouse Model of Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet and in HepG2 Human Hepatocellular Carcinoma Cells Treated with Oleic Acid.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Carcinoma, Hepatocellular; Cholesterol; | 2020 |
CKD-5, a novel pan-histone deacetylase inhibitor, synergistically enhances the efficacy of sorafenib for hepatocellular carcinoma.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line, Tumor; C | 2020 |
Feasibility of Phosphoproteomics on Leftover Samples After RNA Extraction With Guanidinium Thiocyanate.
Topics: Animals; Carcinoma, Hepatocellular; Cell Line; Chloroform; DNA Damage; Feasibility Studies; Guanidin | 2021 |
Induction of Divergent Cell Death Pathways by Urea and Carbohydrazide Derivatives.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Endoplasmic Reticulum | 2022 |
Using gene expression database to uncover biology functions of 1,4-disubstituted 1,2,3-triazole analogues synthesized via a copper (I)-catalyzed reaction.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Cell Line, Tumor; Copper; Cu | 2017 |
Tributyl phosphate impairs the urea cycle and alters liver pathology and metabolism in mice after short-term exposure based on a metabonomics study.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carcinoma, Hepatocellular; Constitutive Androstane Receptor; | 2017 |
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
Topics: Adult; Aged; Arginine; Blood Vessels; Carcinoma, Hepatocellular; Cholesterol; Fatty Acids; Female; G | 2019 |
Manipulating hepatocellular carcinoma cell fate in orthogonally cross-linked hydrogels.
Topics: Carcinoma, Hepatocellular; Cell Dedifferentiation; Cell Line, Tumor; Cell Survival; Cells, Immobiliz | 2014 |
Indoline ureas as potential anti-hepatocellular carcinoma agents targeting VEGFR-2: Synthesis, in vitro biological evaluation and molecular docking.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; Dose-Response Relationship, Dr | 2015 |
Reply to F.V. Negri et al.
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Emulsions; Female; Hand-Foot Syndrome; Humans; Liv | 2015 |
Urea-Based Cream to Prevent Sorafenib-Induced Hand-and-Foot Skin Reaction: Which Evidence?
Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Emulsions; Female; Hand-Foot Syndrome; Humans; Liv | 2015 |
Culture and Functional Characterization of Human Hepatoma HepG2 Cells.
Topics: Carcinoma, Hepatocellular; Cell Culture Techniques; Cytochrome P-450 Enzyme System; Glutathione Tran | 2015 |
Targeting protein arginine methyltransferase 5 inhibits human hepatocellular carcinoma growth via the downregulation of beta-catenin.
Topics: Animals; Apoptosis; beta Catenin; Carcinoma, Hepatocellular; Cell Cycle; Cell Line, Tumor; Cell Move | 2015 |
Aminopeptidase N inhibitor 4cc synergizes antitumor effects of 5-fluorouracil on human liver cancer cells through ROS-dependent CD13 inhibition.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; CD13 | 2015 |
Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinib.
Topics: Administration, Topical; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Carcinom | 2008 |
Human liver progenitor cell lines are readily established from non-tumorous tissue adjacent to hepatocellular carcinoma.
Topics: AC133 Antigen; Adult Stem Cells; Animals; Antigens, CD; Antigens, Differentiation; Antigens, Neoplas | 2010 |
Alginate-encapsulated human hepatoma C3A cells for use in a bioartificial liver device - the hybrid-MDS.
Topics: Albumins; Alginates; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chromatography | 2009 |
The study of specific and nonspecific hepatoma cells behavior by means of plasma-treated substrates.
Topics: Biocompatible Materials; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Differentiation; C | 2010 |
DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma.
Topics: Carbamoyl-Phosphate Synthase (Ammonia); Carcinoma, Hepatocellular; Cell Line, Tumor; CpG Islands; DN | 2011 |
A translational study "case report" on the small molecule "energy blocker" 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside.
Topics: Adolescent; Ammonia; Antineoplastic Agents, Alkylating; Carcinoma, Hepatocellular; Energy Metabolism | 2012 |
t-AUCB, an improved sEH inhibitor, suppresses human glioblastoma cell growth by activating NF-κB-p65.
Topics: Apoptosis; Benzoates; Blotting, Western; Brain Neoplasms; Carcinoma, Hepatocellular; Cell Cycle; Cel | 2012 |
Regulation of insulin receptor function by a small molecule insulin receptor activator.
Topics: 3T3 Cells; Adipocytes; Animals; Biological Transport; Blotting, Western; Carcinoma, Hepatocellular; | 2002 |
Synthesis and biological activity of carbocyclic lexitropsins with a bioreductive fragment.
Topics: Antineoplastic Agents; Benzamides; Carcinoma, Hepatocellular; Cell Survival; Humans; Liver Neoplasms | 2002 |
Inhibition of microtubule polymerization by 3-bromopropionylamino benzoylurea (JIMB01), a new cancericidal tubulin ligand.
Topics: Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cyclin B; Cyclin B | 2003 |
Histamine formation and tumor growth.
Topics: Animals; Carcinoma, Hepatocellular; Dihydroxyphenylalanine; Histamine; Liver Neoplasms; Liver Neopla | 1962 |
PHASE II STUDIES OF HYDROXYUREA (NSC-32065) IN ADULTS: MISCELLANEOUS TUMORS.
Topics: Adenocarcinoma; Antineoplastic Agents; Carcinoma, Hepatocellular; Carcinoma, Squamous Cell; Carcinom | 1964 |
Ornithine transcarbamylase and arginase I deficiency are responsible for diminished urea cycle function in the human hepatoblastoma cell line HepG2.
Topics: Arginase; Base Sequence; Carcinoma, Hepatocellular; Cell Line, Tumor; DNA Primers; Gene Expression; | 2007 |
Osmotic regulation of betaine homocysteine-S-methyltransferase expression in H4IIE rat hepatoma cells.
Topics: Animals; Betaine; Betaine-Homocysteine S-Methyltransferase; Carcinoma, Hepatocellular; Cell Line, Tu | 2007 |
Cells for bioartificial liver devices: the human hepatoma-derived cell line C3A produces urea but does not detoxify ammonia.
Topics: Ammonia; Carcinoma, Hepatocellular; Cell Culture Techniques; Cell Line, Tumor; Humans; Liver, Artifi | 2008 |
Arginase release by primary hepatocytes and liver slices results in rapid conversion of arginine to urea in cell culture media.
Topics: Animals; Arginase; Arginine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Cells, Cult | 2008 |
Protein complexes of intermediate-sized filaments: melting of cytokeratin complexes in urea reveals different polypeptide separation characteristics.
Topics: Animals; Breast Neoplasms; Carcinoma, Hepatocellular; Cattle; Cell Line; Cytoskeleton; Electrophores | 1983 |
Regulation of urea cycle enzymes in transplantable hepatomas and in the livers of tumor-bearing rats and humans.
Topics: Animals; Betamethasone; Bucladesine; Carcinoma, Hepatocellular; Cell Line; Dietary Proteins; Enzyme | 1981 |
Eleven years experience of oral urea treatment in liver malignancies.
Topics: Adenocarcinoma; Administration, Oral; Adult; Aged; Carcinoma, Hepatocellular; Drug Administration Sc | 1981 |
[A new liver support system composed of functional human cells and a radial-flow bioreactor].
Topics: Albumins; alpha-Fetoproteins; Ammonia; Artificial Organs; Carcinoma, Hepatocellular; Cells, Cultured | 1994 |
Effects of dexamethasone and interleukin-6 on urea production by human hepatocytes in vitro.
Topics: Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Dexamethasone; Humans; Interleukin-6; Kin | 1997 |
The ring fragmentation product of thymidine C5-hydrate when present in DNA is repaired by the Escherichia coli Fpg and Nth proteins.
Topics: Bacterial Proteins; Base Composition; Carcinoma, Hepatocellular; Cell Extracts; Deoxyribonuclease (P | 1998 |
Physicochemical characterization of an antagonistic human interleukin-6 dimer.
Topics: Carcinoma, Hepatocellular; Chemical Phenomena; Chemistry, Physical; Circular Dichroism; Dimerization | 1998 |
Metabolic capacities in cultured human hepatocytes obtained by a new isolating procedure from non-wedge small liver biopsies.
Topics: Adult; Aged; Aged, 80 and over; Albumins; Biopsy; Blotting, Western; Carcinoma, Hepatocellular; Cell | 1998 |
Heterogeneity of human alpha-fetoprotein as revealed by isoelectric focusing in urea-containing gels.
Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Electrophoresis, Polyacrylamide Gel; Genetic Variatio | 1978 |
Dissociation and reconstitution of chromatin without appreciable degradation of the proteins.
Topics: Animals; Carcinoma, Hepatocellular; Chromatin; DNA-Directed RNA Polymerases; Electrophoresis, Polyac | 1975 |
Sulfhydryl group quantitation of hepatoma and liver microsomal fractions.
Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Cell Fractionation; Disulfides; Edetic Acid; Endopl | 1975 |
Tumor-specific alkaline phosphatase in hepatoma.
Topics: Adult; Alkaline Phosphatase; Carcinoma, Hepatocellular; Edetic Acid; Female; Fetus; Humans; Imidazol | 1975 |
The results of urea-treatment in liver maligancies.
Topics: Administration, Oral; Adult; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; | 1975 |
Urea synthesis in Novikoff and Morris hepatomas.
Topics: Animals; Carbamoyl-Phosphate Synthase (Ammonia); Carcinoma, Hepatocellular; Fasting; Liver; Liver Ne | 1977 |
Increased de novo pyrimidine nucleotide synthesis in liver induced by ammonium ions in amounts surpassing the urea cycle capacity.
Topics: Animals; Azauridine; Carbamoyl-Phosphate Synthase (Ammonia); Carbamoyl-Phosphate Synthase (Glutamine | 1977 |
Characterization and subunit analysis of ferritin isolated from normal and malignant human liver.
Topics: Carcinoma, Hepatocellular; Chemical Phenomena; Chemistry; Chromatography, Gel; Electrophoresis, Poly | 1975 |
Nuclear protein changes in rat hepatomas correlating with growth rate.
Topics: Acetates; Animals; Carcinoma, Hepatocellular; Chick Embryo; Densitometry; Electrophoresis, Polyacryl | 1975 |
A comparative study of the protein components of ribonucleoprotein particles isolated from rat liver and hepatoma nuclei.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleus; Electrophoresis, Polyacrylamide Gel; Liver; Liver | 1973 |
Letter: Regression of liver cancer with oral urea.
Topics: Administration, Oral; Aged; Carcinoma, Hepatocellular; Female; Humans; Liver Neoplasms; Male; Middle | 1974 |
Establishment of a clonal strain of hepatoma cells which maintain in culture the five enzymes of the urea cycle.
Topics: Ammonia; Animals; Arginase; Arginine; Bucladesine; Carbamates; Carcinoma, Hepatocellular; Chromosome | 1974 |
Effect of azo-dye carcinogenesis on enzymes concerned with urea synthesis in rat liver.
Topics: Animals; Arginase; Carcinogens; Carcinoma, Hepatocellular; Glucosephosphate Dehydrogenase; Ligases; | 1964 |
Studies on the function of intracellular ribonucleases. V. Ribonuclease activity in ribosomes and polysomes prepared from rat liver and hepatomas.
Topics: Animals; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Edetic Acid; Hydrogen-Ion Conc | 1966 |
Subtotal hepatectomy for primary hepatic carcinoma.
Topics: Adolescent; Bilirubin; Carcinoma, Hepatocellular; Cholestasis; Female; Hepatectomy; Humans; Liver Ab | 1967 |
Stability of nucleolar 45-S RNA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Nucleolus; Centrifugation, Density Gradient; Hydrogen-Ion C | 1967 |
Investigation of albumin metabolism in man.
Topics: Amino Acids; Carbon Isotopes; Carcinoma, Hepatocellular; Celiac Disease; Humans; Hypertension; Liver | 1967 |
(Mg2+ Na+ K+)-ATPase activity of liver from tumor bearing rats.
Topics: Adenosine Triphosphatases; Animals; Binding Sites; Carcinoma, Hepatocellular; Enzyme Activation; Hyd | 1969 |
Toxicity, tissue changes, and tumor induction in inbred Swiss mice by methylnitrosamine and -amide compounds.
Topics: Adenoma; Animals; Animals, Newborn; Blood Cell Count; Bone Marrow; Bone Marrow Cells; Carcinoma, Hep | 1970 |
Carcinogenicity of a single administration of N-nitrosomethylurea: a comparison between newborn and 5-week-old mice and rats.
Topics: Adenoma; Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Female; Gastrointestinal | 1970 |
[The cancer-risk in man from synthetic sweetening agents].
Topics: Animals; Carcinoma, Hepatocellular; Cyclamates; Female; Liver Neoplasms; Lung Neoplasms; Lymphoma, N | 1971 |
A circular dichroism study on the conformation of DNA in rat liver chromatin.
Topics: Animals; Ascitic Fluid; Carcinoma, Hepatocellular; Cell Line; Chemical Phenomena; Chemistry; Chromos | 1971 |
Some aspects of the mechanism of action of 1-propyl-1-nitrosourea.
Topics: Amino Acids; Animals; Arginine; Carbon Isotopes; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular | 1970 |
A study of various electrophoretic and inhibition techniques for separating serum alkaline phosphatase isoenzymes.
Topics: Acrylamides; Alkaline Phosphatase; Bile; Bone and Bones; Buffers; Carcinoma, Hepatocellular; Clinica | 1972 |
Histone phosphorylation and DNA synthesis are linked in synchronous cultures of HTC cells.
Topics: Benzocycloheptenes; Carcinoma, Hepatocellular; Cell Line; Cells, Cultured; DNA; Electrophoresis; His | 1972 |
Lysine-rich histone phosphorylation. A positive correlation with cell replication.
Topics: Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Cell Division; Cell Line; Densitometry; El | 1972 |
Effect of neuraminic acid removal on the properties of a variant alkaline phosphatase in hepatoma.
Topics: Alkaline Phosphatase; Aminocaproates; Carcinoma, Hepatocellular; Edetic Acid; Enzyme Activation; Gen | 1972 |
Studies on a variant alkaline phosphatase in sera of patients with hepatocellular carcinoma.
Topics: Acrylamides; Alkaline Phosphatase; Amino Acids; Animals; Antibody Specificity; Carcinoma, Hepatocell | 1972 |
Turnover of deoxyribonucleic acid, histones, and lysine-rich histone phosphate in hepatoma tissue culture cells.
Topics: Carcinoma, Hepatocellular; Cell Line; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Half-Life; | 1972 |
Molecular nature of F 1 histone phosphorylation in cultured hepatoma cells.
Topics: Carcinoma, Hepatocellular; Cell Line; Electrophoresis, Polyacrylamide Gel; Histones; Isotope Labelin | 1972 |
[Ornithine-carbamoyl-transferase and its clinical valve].
Topics: Ammonia; Carbon Dioxide; Carcinoma, Hepatocellular; Clinical Enzyme Tests; Hepatitis A; Jaundice; Li | 1972 |
Protein turnover in microsomal subfractions of liver and Morris hepatomas 7800 and 9618A.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Centrifugation, Density Gradient; Cholesterol; | 1973 |
Inhibition of urea on the hepatocarcinogensis induced by N, N-dimethyl-4-aminoazobenzene in rats.
Topics: Animals; Carcinoma, Hepatocellular; Female; Liver Neoplasms; p-Dimethylaminoazobenzene; Rats; Urea | 1973 |
Further investigation of a variant of the placental alkaline phosphatase in human hepatic carcinoma.
Topics: Alkaline Phosphatase; Animals; Carcinoma, Hepatocellular; Chromatography, Gel; Cross Reactions; Edet | 1974 |
Nuclear protein changes during the nitrosamine-induced carcinogenesis of rat liver.
Topics: Animals; Binding Sites; Carbon Radioisotopes; Carcinogens; Carcinoma, Hepatocellular; Cell Nucleus; | 1974 |