Page last updated: 2024-10-21

urea and Hepatic Failure

urea has been researched along with Hepatic Failure in 21 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

ExcerptRelevanceReference
"Short-term administration of Galactosamine to experimental animals causes liver damage and acute liver failure (ALF), as well as acute renal failure in some cases."7.81D-Galactosamine Intoxication in Experimental Animals: Is it Only an Experimental Model of Acute Liver Failure? ( Brytan, M; Dyrla, P; Gil, J; Kade, G; Nowak, Z; Patera, J; Saracyn, M; Wańkowicz, Z; Zdanowski, R, 2015)
"We aimed to determine the association between blood urea level and incident cirrhosis, hepatic decompensation, and hepatocellular carcinoma in chronic liver disease (CLD) patients."4.12U-shaped relationship between urea level and hepatic decompensation in chronic liver diseases. ( Chan, HL; Hui, VW; Lai, JC; Lin, H; Liu, K; Tse, YK; Wong, GL; Wong, VW; Yip, TC; Zhang, X, 2022)
"Short-term administration of Galactosamine to experimental animals causes liver damage and acute liver failure (ALF), as well as acute renal failure in some cases."3.81D-Galactosamine Intoxication in Experimental Animals: Is it Only an Experimental Model of Acute Liver Failure? ( Brytan, M; Dyrla, P; Gil, J; Kade, G; Nowak, Z; Patera, J; Saracyn, M; Wańkowicz, Z; Zdanowski, R, 2015)
"The proposed discrimination methodology was applied to plasma and tissue (liver) metabolic profiling data describing the time progression of liver dysfunction in a rat model of acute hepatic failure generated by d-galactosamine (GalN) injection."3.72Identification of optimal classification functions for biological sample and state discrimination from metabolic profiling data. ( Hwang, D; Lee, K; Stephanopoulos, G; Stephanopoulos, GN; Yarmush, ML; Yokoyama, T, 2004)
"Renal glutamine uptake and subsequent urinary ammonia excretion could be an important alternative pathway of ammonia disposal from the body during liver failure (diminished urea synthesis), but this pathway has received little attention."3.68Renal ammonia and glutamine metabolism during liver insufficiency-induced hyperammonemia in the rat. ( Dejong, CH; Deutz, NE; Soeters, PB, 1993)
"Acute liver failure was present in 4 (25%) and acute-on-chronic liver failure in 8 (75%)."1.72Ammonia Clearance with Different Continuous Renal Replacement Therapy Techniques in Patients with Liver Failure. ( Baldwin, I; Bellomo, R; Fealy, N; Fisher, C; Naorungroj, T, 2022)
"Bilirubin and urea were monitored as measures of protein-bound and water-soluble toxins."1.31Hemodynamic changes during a single treatment with the molecular adsorbents recirculating system in patients with acute-on-chronic liver failure. ( Hansen, BA; Larsen, FS; Schmidt, LE; Svendsen, LB; Sørensen, VR, 2001)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's11 (52.38)29.6817
2010's6 (28.57)24.3611
2020's2 (9.52)2.80

Authors

AuthorsStudies
Lin, H1
Wong, GL1
Zhang, X1
Yip, TC1
Liu, K1
Tse, YK1
Hui, VW1
Lai, JC1
Chan, HL1
Wong, VW1
Fisher, C1
Baldwin, I1
Fealy, N1
Naorungroj, T1
Bellomo, R1
Slack, AJ1
Auzinger, G1
Willars, C1
Dew, T1
Musto, R1
Corsilli, D1
Sherwood, R1
Wendon, JA1
Bernal, W1
Wang, XQ1
Tang, NH1
Zhang, FY1
Li, XJ1
Chen, YL1
Samuel, N1
Politansky, AK1
Hoffman, R1
Itzkovich, S1
Mandel, H1
Saracyn, M1
Zdanowski, R1
Brytan, M1
Kade, G1
Nowak, Z1
Patera, J1
Dyrla, P1
Gil, J1
Wańkowicz, Z1
Sponholz, C1
Matthes, K1
Rupp, D1
Backaus, W1
Klammt, S2
Karailieva, D1
Bauschke, A1
Settmacher, U1
Kohl, M1
Clemens, MG1
Mitzner, S1
Bauer, M1
Kortgen, A1
Weismüller, TJ1
Negm, A1
Becker, T1
Barg-Hock, H1
Klempnauer, J1
Manns, MP1
Strassburg, CP1
Lee, JH1
Lee, DH1
Park, JK1
Kim, SK1
Kwon, CH1
Lee, SK1
Wang, X1
Zhou, X1
Miao, J1
Fan, D1
Lima, EQ1
Zanetta, DM1
Castro, I1
Massarollo, PC1
Mies, S1
Machado, MM1
Yu, L1
Arranz, J1
Soriano, A1
Garcia, I2
Concepción, MT1
Navarro, J1
Arteaga, A1
Filella, X1
Gonzalez, F1
Fernández, C1
Barrera, M1
Muñoz, L1
Perera, AJ1
Pozo, JL1
Jiménez, A1
Macia, M1
Arteaga, I1
Lee, K1
Hwang, D1
Yokoyama, T1
Stephanopoulos, G1
Stephanopoulos, GN1
Yarmush, ML1
Ludlow, JW1
Bruce, AT1
Kulik, MJ1
Meheux, SO1
McCoy, DW1
Asfeldt, TM1
Evenepoel, P1
Laleman, W1
Wilmer, A1
Claes, K1
Maes, B1
Kuypers, D1
Bammens, B1
Nevens, F1
Vanrenterghem, Y1
Stefoni, S1
Colì, L1
Bolondi, L1
Donati, G2
Ruggeri, G1
Feliciangeli, G1
Piscaglia, F1
Silvagni, E1
Sirri, M1
Baraldi, O1
Soverini, ML1
Cianciolo, G1
Boni, P1
Patrono, D1
Ramazzotti, E1
Motta, R1
Roda, A1
Simoni, P1
Magliulo, M1
Borgnino, LC1
Ricci, D1
Mezzopane, D1
Cappuccilli, ML1
Vienken, J1
Christmann, H1
Nikolic, J1
Stojanovic, I1
Pavlovic, R1
Sokolovic, D1
Bjelakovic, G1
Beninati, S1
Dejong, CH1
Deutz, NE1
Soeters, PB1
Stange, J1
Mitzner, SR1
Risler, T1
Erley, CM1
Lauchart, W1
Goehl, H1
Peszynski, P1
Freytag, J1
Hickstein, H1
Löhr, M1
Liebe, S1
Schareck, W1
Hopt, UT1
Schmidt, R1
Schmidt, LE1
Sørensen, VR1
Svendsen, LB1
Hansen, BA1
Larsen, FS1

Reviews

2 reviews available for urea and Hepatic Failure

ArticleYear
Allogeneic cell therapy for the treatment of liver disease.
    Progress in transplantation (Aliso Viejo, Calif.), 2005, Volume: 15, Issue:2

    Topics: Cell Separation; Cell Survival; Cell Transplantation; Clinical Trials, Phase I as Topic; Coumarins;

2005
How can liver toxins be removed? Filtration and adsorption with the Prometheus system.
    Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy, 2006, Volume: 10, Issue:2

    Topics: Bile Acids and Salts; Bilirubin; Creatinine; Extracorporeal Circulation; Humans; Kinetics; Liver Fai

2006

Trials

1 trial available for urea and Hepatic Failure

ArticleYear
Molecular adsorbent recirculating system and single-pass albumin dialysis in liver failure--a prospective, randomised crossover study.
    Critical care (London, England), 2016, Jan-04, Volume: 20

    Topics: Bile Acids and Salts; Bilirubin; Biomarkers; Creatinine; Cross-Over Studies; Extracorporeal Circulat

2016

Other Studies

18 other studies available for urea and Hepatic Failure

ArticleYear
U-shaped relationship between urea level and hepatic decompensation in chronic liver diseases.
    Clinical and molecular hepatology, 2022, Volume: 28, Issue:1

    Topics: Carcinoma, Hepatocellular; Elasticity Imaging Techniques; Humans; Liver Cirrhosis; Liver Failure; Li

2022
Ammonia Clearance with Different Continuous Renal Replacement Therapy Techniques in Patients with Liver Failure.
    Blood purification, 2022, Volume: 51, Issue:10

    Topics: Acute Kidney Injury; Adult; Ammonia; Continuous Renal Replacement Therapy; Creatinine; Humans; Hyper

2022
Ammonia clearance with haemofiltration in adults with liver disease.
    Liver international : official journal of the International Association for the Study of the Liver, 2014, Volume: 34, Issue:1

    Topics: Adult; Ammonia; Female; Hemodiafiltration; Humans; Hyperammonemia; Liver Failure; Male; Middle Aged;

2014
Therapeutic evaluation of a microbioartificial liver with recombinant HepG2 cells for rats with hepatic failure.
    Expert opinion on biological therapy, 2013, Volume: 13, Issue:11

    Topics: Ammonia; Animals; Arginase; Bioreactors; Galactosamine; Hep G2 Cells; Humans; Implants, Experimental

2013
Coagulopathy unmasking hepatic failure in a child with ornithine transcarbamylase deficiency.
    The Israel Medical Association journal : IMAJ, 2013, Volume: 15, Issue:12

    Topics: Amino Acids, Essential; Blood Coagulation Tests; Child, Preschool; Diagnosis, Differential; Diet, Pr

2013
D-Galactosamine Intoxication in Experimental Animals: Is it Only an Experimental Model of Acute Liver Failure?
    Medical science monitor : international medical journal of experimental and clinical research, 2015, May-22, Volume: 21

    Topics: Acute Kidney Injury; Alanine Transaminase; Albumins; Ammonia; Animals; Aspartate Aminotransferases;

2015
The introduction of MELD-based organ allocation impacts 3-month survival after liver transplantation by influencing pretransplant patient characteristics.
    Transplant international : official journal of the European Society for Organ Transplantation, 2009, Volume: 22, Issue:10

    Topics: Adolescent; Adult; Aged; Cold Ischemia; Creatinine; Female; Graft Survival; Humans; Kaplan-Meier Est

2009
Potentiality of immobilized pig hepatocyte spheroids in bioartificial liver system.
    Transplantation proceedings, 2012, Volume: 44, Issue:4

    Topics: Alanine Transaminase; Albumins; Animals; Aspartate Aminotransferases; Cell Survival; Cells, Immobili

2012
[Clinical application of molecular adsorbent recirculating system-artificial liver support system].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002, Volume: 10, Issue:3

    Topics: Ammonia; Humans; Liver Failure; Liver, Artificial; Urea

2002
Risk factors for development of acute renal failure after liver transplantation.
    Renal failure, 2003, Volume: 25, Issue:4

    Topics: Acute Kidney Injury; Adult; Bilirubin; Biomarkers; Blood Transfusion; Brazil; Creatinine; Cyclospori

2003
Association between anatomopathologic graft disorders during reperfusion and vena cava sIL-2r in orthotopic liver transplantation.
    Transplantation proceedings, 2003, Volume: 35, Issue:5

    Topics: Drug Therapy, Combination; Hepatectomy; Humans; Hydrogen-Ion Concentration; Immunosuppressive Agents

2003
Identification of optimal classification functions for biological sample and state discrimination from metabolic profiling data.
    Bioinformatics (Oxford, England), 2004, Apr-12, Volume: 20, Issue:6

    Topics: Algorithms; Amino Acids; Ammonia; Animals; Biomarkers; Diagnosis, Computer-Assisted; Galactosamine;

2004
Detoxifying capacity and kinetics of prometheus--a new extracorporeal system for the treatment of liver failure.
    Blood purification, 2005, Volume: 23, Issue:5

    Topics: Bile Acids and Salts; Bilirubin; Creatinine; Extracorporeal Circulation; Female; Humans; Kinetics; L

2005
Molecular adsorbent recirculating system (MARS) application in liver failure: clinical and hemodepurative results in 22 patients.
    The International journal of artificial organs, 2006, Volume: 29, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Ammonia; Bilirubin; Blood Pressure; Chenodeoxycholic Acid; Cholic

2006
The role of L-arginine in toxic liver failure: interrelation of arginase, polyamine catabolic enzymes and nitric oxide synthase.
    Amino acids, 2007, Volume: 32, Issue:1

    Topics: Amine Oxidase (Copper-Containing); Animals; Arginase; Arginine; Drug Synergism; Liver Failure; Male;

2007
Renal ammonia and glutamine metabolism during liver insufficiency-induced hyperammonemia in the rat.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:6

    Topics: Ammonia; Animals; Glutamates; Glutamic Acid; Glutamine; Hydrogen-Ion Concentration; Kidney; Kinetics

1993
Molecular adsorbent recycling system (MARS): clinical results of a new membrane-based blood purification system for bioartificial liver support.
    Artificial organs, 1999, Volume: 23, Issue:4

    Topics: Adsorption; Adult; Ammonia; Bilirubin; Cholinesterases; Creatinine; Female; Hepatic Encephalopathy;

1999
Hemodynamic changes during a single treatment with the molecular adsorbents recirculating system in patients with acute-on-chronic liver failure.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2001, Volume: 7, Issue:12

    Topics: Acute Disease; Adult; Bilirubin; Blood Pressure; Chronic Disease; Female; Hemodynamics; Humans; Live

2001