urea and Hematuria studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

Excerpt	Relevance	Reference
"Hematuria is a rare complication seen in patients with hemoglobin C trait."	5.31	Urea resolves gross hematuria in a 15 year old with hemoglobin C trait. ( Sakarcan, A; Stallworth, J, 2001)
"Unilateral hematuria is a vaso-occlusive complication of the sickle syndromes, especially the sickle cell trait."	5.29	Treatment of sickle cell trait hematuria with oral urea. ( Katz, A; Pariser, S, 1994)
"Logistic regression analysis showed that hematuria, hemoglobin, urea, complement 3, urinary microalbumin and urinary microalbumin/creatinine are related to Lee's classification of IgAN."	4.12	Establishing a Non-Invasive Gradeing Model for Primary IgA Nephropathy Based on Multi-Center Population. ( Chen, F; Chen, H; Liu, J; Liu, Z; Yang, H; Zhang, H; Zhao, L, 2022)
" Elevated plasma urea and creatinine levels were accompanied by decrease in protein and albumin levels, followed by hematuria, proteinuria and bilirubinuria."	3.69	Toxicity evaluation of freshwater cyanobacterium Microcystis aeruginosa PCC 7806: II. Nephrotoxicity in rats. ( Bhattacharya, R; Dangi, RS; Rao, PV; Sugendran, K, 1997)
"The clinical and biochemical features of 54 children with Nephrotic Syndrome seen over a period of 6 years and the response to Prednisolone therapy in 43 cases is presented."	3.65	Nephrotic syndrome in children-a clinical study. ( Rahimtoola, RJ; Wazir, MD, 1976)
" The urine samples were also examined for white cells, casts, bacteriuria and the concentration of urea, creatinine, electrolytes and protein."	3.65	What the urine contains following athletic competition. ( Abernethy, MH; Bailey, RR; Dann, E; Gillies, AH; Lynn, KL; Neale, TJ, 1976)
"Hematuria is a rare complication seen in patients with hemoglobin C trait."	1.31	Urea resolves gross hematuria in a 15 year old with hemoglobin C trait. ( Sakarcan, A; Stallworth, J, 2001)
"We studied 38 patients with acute renal failure (ARF) due to malaria over a 5-year period between 1990 and 1994 at the Institute of Urology and Transplantation."	1.29	Predictors of outcome in malarial renal failure. ( Abbas, K; Ahmad, E; Akhtar, F; Naqvi, A; Naqvi, R; Rizvi, A; Yazdani, I, 1996)
"Mild hypertension was already observed at 8 weeks of age."	1.27	Development of hypertension and proteinuria with age in fawn-hooded rats. ( de Jong, W; Kuijpers, MH; Provoost, AP, 1986)
"Renal failure and hypertension have been reported and long-term follow up is necessary to clarify the natural history of the disease."	1.25	Recurrent haematuria and mesangial IgA deposition. ( Brown, GW; Davies, DR; Jones, NF; Tighe, JR, 1973)

Timeframe	Studies, this research(%)	All Research%
pre-1990	44 (81.48)	18.7374
1990's	6 (11.11)	18.2507
2000's	3 (5.56)	29.6817
2010's	0 (0.00)	24.3611
2020's	1 (1.85)	2.80

Authors	Studies
Liu, J	1
Yang, H	1
Chen, F	1
Zhao, L	1
Zhang, H	1
Chen, H	1
Liu, Z	1
Duvic, C	1
Bordier, L	1
Hertig, A	1
Ridel, C	1
Didelot, F	1
Herody, M	1
Nédélec, G	1
WITH, TK	1
PETERSEN, TD	1
SAKAMOTO, K	1
BERGER, J	1
DE MONTERA, H	1
ZATUCHNI, J	1
ARMENTO, DF	1
MENZEL, PH	1
SAFAR, M	1
BARIETY, J	1
LAGRUE, G	1
SAMARCQ, P	1
MILLIEZ, P	1
HELBIG, W	1
VOIGT, KG	1
SAMUELS, ML	1
HOWE, CD	1
Gupta, BD	1
Sharma, P	1
Bagla, J	1
Parakh, M	1
Soni, JP	1
Ward, JN	1
Draper, JW	1
Lavengood, RW	1
Kapoor, A	1
Mowbray, JF	1
Porter, KA	1
Peart, WS	1
Bajaj, AK	1
Gupta, SC	1
Sinha, SN	1
Govil, DC	1
Gaur, UC	1
Kumar, R	1
Pariser, S	2
Katz, A	1
Naqvi, R	1
Ahmad, E	1
Akhtar, F	1
Yazdani, I	1
Abbas, K	1
Naqvi, A	1
Rizvi, A	1
Bhattacharya, R	1
Sugendran, K	1
Dangi, RS	1
Rao, PV	1
Smeda, JS	1
Kamitsuji, H	1
Nakajima, M	1
Kawahara, S	1
Nishimura, T	1
Sakarcan, A	1
Stallworth, J	1
Srivastava, RN	2
Mayekar, G	2
Anand, R	1
Choudhry, VP	1
Ghai, OP	2
Tandon, HD	1
Keller, H	1
Reutter, FW	1
Held, E	1
Wazir, MD	1
Rahimtoola, RJ	1
Bailey, RR	1
Dann, E	1
Gillies, AH	1
Lynn, KL	1
Abernethy, MH	1
Neale, TJ	1
Florman, AL	1
Schacht, RG	1
Becker, MH	1
Genieser, NB	1
Madayag, MA	1
Pollen, JJ	1
Levine, E	1
Van Blerk, PJ	1
Ruiz-Beltrán, R	1
Herrero-Herrero, JI	1
Macías, JF	1
el Matri, A	1
Kechrid, C	1
Ben Abdallah, T	1
Ben Moussa, F	1
Khder, A	1
Ben Maiz, H	1
Ben Ayed, H	1
Pillsworth, TJ	1
Haver, VM	1
Abrass, CK	1
Delaney, CJ	1
Heyns, CF	1
Rimington, PD	1
Kuijpers, MH	1
Provoost, AP	1
de Jong, W	1
Lissoos, I	1
Stickler, GB	1
Shin, MH	1
Burke, EC	1
Holley, KE	1
Miller, RH	1
Segar, WE	1
Popovic-Rolovic, M	1
Wright, FW	1
Ledingham, JG	1
Dunnill, MS	1
Grieve, NW	1
Forbes, MJ	1
Sinclair, L	1
Kumar, P	1
Lancaster-Smith, M	1
Cook, P	1
Stansfeld, A	1
Clark, ML	1
Dawson, AM	1
Davies, DR	1
Tighe, JR	1
Jones, NF	1
Brown, GW	1
Whittle, HC	1
Abdullahi, MT	1
Fakunle, F	1
Parry, EH	1
Rajkovic, AD	1
Yates-Bell, AJ	1
Packham, DA	1
Feng, PH	2
Jayaratnam, FJ	1
Tock, EP	1
Seah, CS	1
Cheah, PS	1
Lee, YK	1
Chandra, RK	1
Nanra, RS	1
Kincaid-Smith, P	1
Addae, SK	1
Anders, D	1
Schlenk, R	1
Viethen, J	1
Scott, WC	1
Brass, H	1
Lapp, H	1
Heintz, R	1
Beck, P	1
Evans, KT	1
Chou, CC	1
Hook, JB	1
Hsieh, CP	1
Burns, TD	1
Dabney, JM	1
Randall, RE	1
Stacy, WK	1
Toone, EC	1
Prout, GR	1
Madge, GE	1
Shadomy, HJ	1
Shadomy, S	1
Utz, JP	1
Malyshev, IuI	1
Dement'eva, AM	1
Karpova, EP	1
Kaninina, TA	1
Kondranin, GV	1
Polianskii, GN	1
Eisenberg, S	1
Gunders, AE	1
Cohen, AM	1

Trial			Phase	Enrollment	Study Type	Start Date	Status
A Multinational Prospective Study on the Duration of Steroid Therapy in Steroid Sensitive Nephrotic Syndrome[NCT03878914]			Phase 4	34 participants (Actual)	Interventional	2019-08-06	Terminated (stopped due to The study was terminated at all but one site because of the pandemic)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
[Urinary status, proteinuria, kidney function tests: diagnosis and significance]. Der Internist, 1976, Volume: 17, Issue:2 Topics: Creatinine; Diagnostic Errors; Glomerular Filtration Rate; Hematuria; Humans; Kidney Concentrating A	1976
[Alport's syndrome: apropos of 8 Tunisian families]. La Tunisie medicale, 1988, Volume: 66, Issue:5 Topics: Adolescent; Adult; Female; Hematuria; Humans; Kidney; Male; Nephritis, Hereditary; Pedigree; Protein	1988

Article	Year
Establishing a Non-Invasive Gradeing Model for Primary IgA Nephropathy Based on Multi-Center Population. Clinical laboratory, 2022, Oct-01, Volume: 68, Issue:10 Topics: Complement C3; Creatinine; Glomerulonephritis, IGA; Hematuria; Humans; Urea	2022
[Macroscopic hematuria associated with sickle cell anemia trait: report of ten cases]. La Revue de medecine interne, 2002, Volume: 23, Issue:8 Topics: Adolescent; Adult; Aminocaproates; Antifibrinolytic Agents; Female; Fluid Therapy; Hematuria; Humans	2002
[Spectrophotometric determination of urea in blood & urine]. Nordisk medicin, 1959, Mar-19, Volume: 61, Issue:12 Topics: Body Fluids; Hematuria; Humans; Spectrophotometry; Urea	1959
IDENTIFICATION OF THE PRESSOR SUBSTANCE PRODUCED IN EXPERIMENTAL NEPHRITIS AND PREVENTION OF THE HYPERTENSION BY A SURGICAL PROCEDURE. The Kobe journal of medical sciences, 1963, Volume: 54 Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Edema; Hematuria; Hypertension; Liver Circul	1963
[CHRONIC NECROTIC FOCAL GLOMERULONEPHRITIS]. Journal d'urologie et de nephrologie, 1964, Volume: 70 Topics: Biopsy; Blood Cell Count; Blood Pressure; Blood Protein Electrophoresis; Cholesterol; Eye Manifestat	1964
PITRESSIN-RESISTANT DIABETES INSIPIDUS AND DIABETES MELLITUS AND BILATERAL HYDRONEPHROSIS. The American journal of the medical sciences, 1964, Volume: 247 Topics: Blood Chemical Analysis; Carbon Dioxide; Chlorides; Diabetes Insipidus; Diabetes Mellitus; Glucose T	1964
[ASSOCIATION OF A NEPHROTIC SYNDROME AND A GOUGEROT-SJOGREN SYNDROME]. La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1964, May-14, Volume: 40 Topics: Blood Protein Electrophoresis; Cholesterol; Erythrocytes; Hematuria; Humans; Lipids; Nephrotic Syndr	1964
[CLINICAL KIDNEY FINDINGS IN LEUKEMIA AND THEIR CORRELATION WITH AUTOPSY RESULTS]. Folia haematologica (Leipzig, Germany : 1928), 1963, Volume: 81 Topics: Autopsy; Blood Chemical Analysis; Blood Urea Nitrogen; Hematuria; Hemorrhagic Disorders; Humans; Kid	1963
RENAL ABNORMALITIES INDUCED BY HYDROXYUREA (NSC-32065). Cancer chemotherapy reports, 1964, Volume: 40 Topics: Antineoplastic Agents; Blood; Hematologic Diseases; Hematuria; Hydroxyurea; Kidney Diseases; Kidney	1964
Renal failure in asphyxiated neonates. Indian pediatrics, 2005, Volume: 42, Issue:9 Topics: Acute Kidney Injury; Apgar Score; Asphyxia Neonatorum; Birth Weight; Case-Control Studies; Causality	2005
A clinical review of polycystic kidney disease in 53 patients. The Journal of urology, 1967, Volume: 98, Issue:1 Topics: Adolescent; Adult; Aged; Angiography; Child; Child, Preschool; Diagnosis, Differential; Female; Hema	1967
Significance of haematuria in hypertensive patients. Lancet (London, England), 1980, Feb-02, Volume: 1, Issue:8162 Topics: Adult; Age Factors; Hematuria; HLA Antigens; Humans; Hypertension; Immunoglobulin A; Urea	1980
Renal functional status in lepromatous leprosy. International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association, 1981, Volume: 49, Issue:1 Topics: Adolescent; Adult; Aged; Child; Creatinine; Erythema Nodosum; Hematuria; Humans; Kidney; Leprosy; Mi	1981
Treatment of sickle cell trait hematuria with oral urea. The Journal of urology, 1994, Volume: 151, Issue:2 Topics: Administration, Oral; Adult; Female; Hematuria; Humans; Sickle Cell Trait; Urea	1994
Predictors of outcome in malarial renal failure. Renal failure, 1996, Volume: 18, Issue:4 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Animals; Antimalarials; Creatinine; Female; Hematuria;	1996
Toxicity evaluation of freshwater cyanobacterium Microcystis aeruginosa PCC 7806: II. Nephrotoxicity in rats. Biomedical and environmental sciences : BES, 1997, Volume: 10, Issue:1 Topics: Alkaline Phosphatase; Analysis of Variance; Animals; Aspartate Aminotransferases; Bilirubin; Chromat	1997
Renal function in stroke-prone rats fed a high-K+ diet. Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:7 Topics: Animals; Blood Pressure; Cerebrovascular Disorders; Creatinine; Dose-Response Relationship, Drug; He	1997
Detection of activated platelets in urine by double immunofluorescence in children with IgA nephropathy. Nephron, 1998, Volume: 78, Issue:2 Topics: Adolescent; Blood Platelets; Child; Female; Fluorescein-5-isothiocyanate; Fluorescent Antibody Techn	1998
Urea resolves gross hematuria in a 15 year old with hemoglobin C trait. Pediatric nephrology (Berlin, Germany), 2001, Volume: 16, Issue:2 Topics: Adolescent; Female; Hematuria; Hemoglobin C Disease; Humans; Infusions, Intravenous; Nephrectomy; Ur	2001
Nephrotic syndrome in indian children. Archives of disease in childhood, 1975, Volume: 50, Issue:8 Topics: Adolescent; Age Factors; Amyloidosis; Child; Child, Preschool; Edema; Female; Glomerulonephritis; He	1975
[Screening and rapid tests in kidney and urinary tract diseases]. Der Internist, 1976, Volume: 17, Issue:9 Topics: Hematuria; Hemoglobinuria; Humans; Hydrogen-Ion Concentration; Kidney Diseases; Myoglobinuria; Prote	1976
Nephrotic syndrome in children-a clinical study. JPMA. The Journal of the Pakistan Medical Association, 1976, Volume: 26, Issue:6 Topics: Age Factors; Albuminuria; Child; Child, Preschool; Cholesterol; Female; Hematuria; Humans; Infant; I	1976
What the urine contains following athletic competition. The New Zealand medical journal, 1976, May-12, Volume: 83, Issue:563 Topics: Bacteriuria; Female; Hematuria; Hemoglobinuria; Hockey; Humans; Male; Myoglobinuria; Proteinuria; Py	1976
Unilateral renal vein thrombosis during mid-childhood. Clinical pediatrics, 1975, Volume: 14, Issue:8 Topics: Anemia, Hemolytic, Autoimmune; Child; Child, Preschool; Chlorides; Creatinine; Female; Hematuria; He	1975
The angiographic evaluation of renal pelvic carcinoma. British journal of urology, 1975, Volume: 47, Issue:4 Topics: Aged; Angiography; Carcinoma, Transitional Cell; Diagnosis, Differential; Female; Hematuria; Humans;	1975
Mechanism of low serum sodium levels in Mediterranean spotted fever. Acta tropica, 1991, Volume: 50, Issue:2 Topics: Adolescent; Adult; Aged; Boutonneuse Fever; Chlorides; Creatinine; Female; Hematuria; Humans; Hypona	1991
Differentiation of renal from non-renal hematuria by microscopic examination of erythrocytes in urine. Clinical chemistry, 1987, Volume: 33, Issue:10 Topics: Diagnosis, Differential; Diagnostic Tests, Routine; Erythrocytes; Female; Glomerulonephritis; Hematu	1987
Intraperitoneal rupture of the bladder causing the biochemical features of renal failure. British journal of urology, 1987, Volume: 60, Issue:3 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Creatinine; Female; Hematuria; Humans; Male; Middle Ag	1987
Development of hypertension and proteinuria with age in fawn-hooded rats. Clinical and experimental pharmacology & physiology, 1986, Volume: 13, Issue:3 Topics: Animals; Blood Pressure; Body Weight; Creatinine; Diuresis; Drinking; Eating; Hematuria; Hypertensio	1986
Simple prostatic hyperplasia in the Bantu. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Mar-03, Volume: 47, Issue:9 Topics: Adult; Aged; Black People; Hematuria; Hernia, Inguinal; Humans; Male; Middle Aged; Prostatectomy; Pr	1973
Diffuse glomerulonephritis associated with infected ventriculoatrial shunt. The New England journal of medicine, 1968, Nov-14, Volume: 279, Issue:20 Topics: Beta-Globulins; Biopsy; Catheterization; Child; Child, Preschool; Drainage; Female; Fluorescent Anti	1968
Serum C3 levels in acute glomerulonephritis and postnephritic children. Archives of disease in childhood, 1973, Volume: 48, Issue:8 Topics: Adolescent; Blood Pressure; Child; Child, Preschool; Complement System Proteins; Creatine; Glomerulo	1973
Polycystic kidneys, renal hamartomas, their variants and complications. Clinical radiology, 1974, Volume: 25, Issue:1 Topics: Acute Kidney Injury; Adult; Angiography; Blood Pressure; Creatinine; Diagnosis, Differential; Female	1974
Lupus nephritis: response to azathioprine. Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:8 Topics: Adolescent; Azathioprine; Edema; Female; Glomerular Filtration Rate; Glomerulonephritis; Hematuria;	1974
Oral urea treatment of hematuria in sickle-cell trait. New York state journal of medicine, 1974, Volume: 74, Issue:12 Topics: Administration, Oral; Adult; Anemia, Sickle Cell; Female; Hematuria; Humans; Sickle Cell Trait; Urea	1974
Alpha1 antitrypsin deficiency in chronic liver disease, and a report of cirrhosis and emphysema in adult members of a family. British medical journal, 1974, Mar-02, Volume: 1, Issue:5904 Topics: Adult; Alkaline Phosphatase; alpha 1-Antitrypsin; Bilirubin; Collateral Circulation; Creatinine; Ele	1974
Recurrent haematuria and mesangial IgA deposition. Journal of clinical pathology, 1973, Volume: 26, Issue:9 Topics: Adolescent; Adult; Basement Membrane; Complement System Proteins; Creatinine; Female; Fluorescent An	1973
Scabies, pyoderma and nephritis in Zaria, Nigeria. A clinical and epidemiological study. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1973, Volume: 67, Issue:3 Topics: Adolescent; Bacteriological Techniques; Child; Child, Preschool; Complement System Proteins; Female;	1973
Giant hydronephrosis in a solitary crossed ectopic kidney. The British journal of surgery, 1972, Volume: 59, Issue:2 Topics: Blood Pressure; Body Temperature; Congenital Abnormalities; Creatinine; Escherichia coli; Hematuria;	1972
Cyclophosphamide in treatment of systemic lupus erythematosus: 7 years' experience. British medical journal, 1973, May-26, Volume: 2, Issue:5864 Topics: Administration, Oral; Adolescent; Adult; Amenorrhea; Blood Cell Count; Cyclophosphamide; Female; Hem	1973
Mortality in systemic lupus erythematosus: a 10-year review. British medical journal, 1973, Dec-29, Volume: 4, Issue:5895 Topics: Adolescent; Adult; Aged; Bronchopneumonia; Cerebrospinal Fluid Proteins; Child; Chlorides; Coma; Cyc	1973
Clinicopathologic correlations in 100 children with the nephrotic syndrome. Indian pediatrics, 1973, Volume: 10, Issue:5 Topics: Adolescent; Child; Child, Preschool; Female; Hematuria; Humans; Hypertension; Infant; Kidney; Male;	1973
Lupus nephritis: clinical course in relation to treatment. Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 2, Issue:0 Topics: Adolescent; Adult; Aged; Azathioprine; Child; Creatinine; Cyclophosphamide; Female; Follow-Up Studie	1973
The kidney in sickle cell disease V: Clinical manifestations. Ghana medical journal, 1973, Volume: 12, Issue:4 Topics: Anemia, Sickle Cell; Bacteriuria; Enuresis; Erythrocyte Count; Glomerulonephritis; Hematuria; Humans	1973
[Long-term study of the idiopathic nephrotic syndrome in childhood (67 children of the Pediatric clinic in Erlangen from 1948-1973) (author's transl)]. Klinische Padiatrie, 1974, Volume: 186, Issue:1 Topics: Adolescent; Adrenal Cortex Hormones; Age Factors; Biopsy; Blood Sedimentation; Child; Child, Prescho	1974
Infusion pyelography in perspective. Clinical radiology, 1968, Volume: 19, Issue:1 Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Child; Child, Preschool; Hematuria; Humans; Hypertensi	1968
[Long term treatment of chronic glomerulonephritis, clinical course and results of renal biopsies]. Archiv fur klinische Medizin, 1969, Volume: 216, Issue:4 Topics: Acetates; Adolescent; Adult; Azathioprine; Biopsy; Blood Pressure; Chloroquine; Female; Glomerulonep	1969
Renal abnormalities in patients with haemophilia and Christmas disease. Clinical radiology, 1972, Volume: 23, Issue:3 Topics: Adolescent; Adult; Aged; Blood Pressure; Hematoma; Hematuria; Hemophilia A; Hemophilia B; Humans; Hy	1972
Effects of radiopaque dyes on renal vascular resistance. The Journal of laboratory and clinical medicine, 1971, Volume: 78, Issue:5 Topics: Animals; Blood Flow Velocity; Blood Pressure; Coloring Agents; Contrast Media; Diatrizoate; Dogs; Ep	1971
Cryptococcal pyelonephritis. The New England journal of medicine, 1968, Jul-11, Volume: 279, Issue:2 Topics: Adrenal Cortex Hormones; Adult; Aged; Amphotericin B; Arthritis, Rheumatoid; Aspirin; Cryptococcosis	1968
[Postoperative changes in the water-salt balance in patients undergoing surgery in connection with diseases of organs of the chest cavity]. Vestnik khirurgii imeni I. I. Grekova, 1968, Volume: 101, Issue:7 Topics: Cardiac Surgical Procedures; Chlorides; Creatinine; Esophageal Neoplasms; Hematuria; Humans; Inflamm	1968
Tick-borne relapsing fever in the Judean hills, including a case with massive haematuria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 1968, Volume: 62, Issue:5 Topics: Adult; Hematuria; Humans; Israel; Male; Relapsing Fever; Tick Infestations; Urea	1968

urea and Hematuria

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