urea has been researched along with Gout in 45 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Gout: Metabolic disorder characterized by recurrent acute arthritis, hyperuricemia and deposition of sodium urate in and around the joints, sometimes with formation of URIC ACID calculi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A case is described in which, after administration of diclofenac for 13 days for arthritis attributed to gout, the patient experienced erythema multiforme followed by muscle weakness, elevation of serum creatine phosphokinase (CPK) level from 101 to 83,770 U/L, 100% muscle isoenzyme, blood urea nitrogen (BUN) level from 15 to 87 mg/dL, creatinine level from 1." | 7.69 | Case report: diclofenac-induced rhabdomyolysis. ( Delrio, FG; Grob, D; Herzlich, B; Park, Y, 1996) |
| "Prazosin was used as additional therapy in seven patients with severe chronic congestive cardiac failure." | 7.66 | Effect of prazosin on renal function in chronic congestive cardiac failure. ( Morgan, TO; Myers, JB; Walker, JN, 1981) |
| " Increased serum uric acid level during this month had been reported in past studies of nongout patients." | 3.80 | The impact of Ramadan fast on patients with gout. ( Artul, S; Badarny, S; Habib, G; Hakim, G; Khazin, F; Khreish, M; Shehadeh, V, 2014) |
| "A case is described in which, after administration of diclofenac for 13 days for arthritis attributed to gout, the patient experienced erythema multiforme followed by muscle weakness, elevation of serum creatine phosphokinase (CPK) level from 101 to 83,770 U/L, 100% muscle isoenzyme, blood urea nitrogen (BUN) level from 15 to 87 mg/dL, creatinine level from 1." | 3.69 | Case report: diclofenac-induced rhabdomyolysis. ( Delrio, FG; Grob, D; Herzlich, B; Park, Y, 1996) |
| "Prazosin was used as additional therapy in seven patients with severe chronic congestive cardiac failure." | 3.66 | Effect of prazosin on renal function in chronic congestive cardiac failure. ( Morgan, TO; Myers, JB; Walker, JN, 1981) |
| "Gout is the most common form of inflammatory arthritis affecting men, and current evidence suggests that genetic factors contribute to its progression." | 1.43 | Genetic variation in WDR1 is associated with gout risk and gout-related metabolic indices in the Han Chinese population. ( Feng, T; Geng, TT; He, N; Jin, TB; Kang, LL; Liu, K; Liu, LJ; Shi, XG; Yuan, DY; Zhang, XY, 2016) |
| "Furthermore, congestive heart failure is associated with impaired creatinine clearance and increased urea and urate, and osteoporosis and hip fractures are characterized by low albumin and cholesterol." | 1.32 | Association of biochemical values with morbidity in the elderly: a population-based Swedish study of persons aged 82 or more years. ( Berg, S; Evrin, PE; Johansson, B; McClearn, G; Nilsson, SE; Takkinen, S; Tryding, N, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (71.11) | 18.7374 |
| 1990's | 3 (6.67) | 18.2507 |
| 2000's | 3 (6.67) | 29.6817 |
| 2010's | 7 (15.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kemter, E | 1 |
| Prueckl, P | 1 |
| Sklenak, S | 1 |
| Rathkolb, B | 1 |
| Habermann, FA | 1 |
| Hans, W | 1 |
| Gailus-Durner, V | 1 |
| Fuchs, H | 1 |
| Hrabě de Angelis, M | 1 |
| Wolf, E | 1 |
| Aigner, B | 1 |
| Wanke, R | 1 |
| Habib, G | 1 |
| Badarny, S | 1 |
| Khreish, M | 1 |
| Khazin, F | 1 |
| Shehadeh, V | 1 |
| Hakim, G | 1 |
| Artul, S | 1 |
| Liu, LJ | 1 |
| Zhang, XY | 1 |
| He, N | 1 |
| Liu, K | 1 |
| Shi, XG | 1 |
| Feng, T | 1 |
| Geng, TT | 1 |
| Yuan, DY | 1 |
| Kang, LL | 1 |
| Jin, TB | 1 |
| Duan, L | 1 |
| Huang, Y | 1 |
| Su, Q | 1 |
| Lin, Q | 1 |
| Liu, W | 1 |
| Luo, J | 1 |
| Yu, B | 1 |
| He, Y | 1 |
| Qian, H | 1 |
| Liu, Y | 1 |
| Chen, J | 1 |
| Shi, G | 1 |
| Ka, T | 1 |
| Inokuchi, T | 1 |
| Tamada, D | 1 |
| Suda, M | 1 |
| Tsutsumi, Z | 1 |
| Okuda, C | 1 |
| Yamamoto, A | 1 |
| Takahashi, S | 1 |
| Moriwaki, Y | 1 |
| Yamamoto, T | 1 |
| Dalbeth, N | 1 |
| Wong, S | 1 |
| Gamble, GD | 1 |
| Horne, A | 1 |
| Mason, B | 1 |
| Pool, B | 1 |
| Fairbanks, L | 1 |
| McQueen, FM | 1 |
| Cornish, J | 1 |
| Reid, IR | 1 |
| Palmano, K | 1 |
| Gudbjartsson, DF | 1 |
| Holm, H | 1 |
| Indridason, OS | 1 |
| Thorleifsson, G | 1 |
| Edvardsson, V | 1 |
| Sulem, P | 1 |
| de Vegt, F | 1 |
| d'Ancona, FC | 1 |
| den Heijer, M | 1 |
| Wetzels, JF | 1 |
| Franzson, L | 1 |
| Rafnar, T | 1 |
| Kristjansson, K | 1 |
| Bjornsdottir, US | 1 |
| Eyjolfsson, GI | 1 |
| Kiemeney, LA | 1 |
| Kong, A | 1 |
| Palsson, R | 1 |
| Thorsteinsdottir, U | 1 |
| Stefansson, K | 1 |
| Huang, CT | 1 |
| Chen, ML | 1 |
| Huang, LL | 1 |
| Mao, IF | 1 |
| BOLLIGER, A | 1 |
| GROSS, R | 1 |
| PERLES, L | 1 |
| MARTINE AU, J | 1 |
| LEPROVOST, J | 1 |
| BATT, RE | 1 |
| CIRKSENA, WJ | 1 |
| LEBHERZ, TB | 1 |
| MCKECHNIE, JK | 1 |
| SIMPSON, FO | 1 |
| WAAL, HJ | 1 |
| GOMBOS, EA | 1 |
| LEE, TH | 1 |
| HARTON, MR | 1 |
| CUMMINGS, JW | 1 |
| GONICK, HC | 1 |
| RUBINI, ME | 1 |
| GLEASON, IO | 1 |
| SOMMERS, SC | 1 |
| Nilsson, SE | 1 |
| Takkinen, S | 1 |
| Tryding, N | 1 |
| Evrin, PE | 1 |
| Berg, S | 1 |
| McClearn, G | 1 |
| Johansson, B | 1 |
| FRIEDMAN, M | 1 |
| BYERS, SO | 1 |
| Ganson, NJ | 1 |
| Kelly, SJ | 1 |
| Scarlett, E | 1 |
| Sundy, JS | 1 |
| Hershfield, MS | 1 |
| Emmerson, BT | 1 |
| Myers, JB | 1 |
| Morgan, TO | 1 |
| Walker, JN | 1 |
| Gibson, T | 1 |
| Potter, C | 1 |
| Simmonds, HA | 1 |
| Rogers, V | 1 |
| Gleadle, RI | 1 |
| Delrio, FG | 1 |
| Park, Y | 1 |
| Herzlich, B | 1 |
| Grob, D | 1 |
| Gillott, TJ | 1 |
| Whallett, A | 1 |
| Zaphiropoulos, G | 1 |
| Scott, JT | 3 |
| Higgens, CS | 1 |
| Marcolongo, R | 1 |
| Calabria, AA | 1 |
| Mazzullo, G | 1 |
| Lalumera, M | 1 |
| Morozzi, G | 1 |
| Cavallo, G | 1 |
| Kullich, W | 1 |
| Ulreich, A | 1 |
| Klein, G | 1 |
| Mohanaruban, K | 1 |
| Joglekar, M | 1 |
| Swift, CG | 1 |
| Tomlinson, K | 1 |
| Loebl, WY | 2 |
| Boine, L | 1 |
| Caraway, WT | 1 |
| Robinson, RG | 1 |
| Corrigan, AB | 1 |
| Ropers, HH | 1 |
| Mertz, DP | 1 |
| Fischer, V | 1 |
| Schröter, M | 1 |
| Bennett, RM | 1 |
| Chait, A | 1 |
| Lewis, B | 1 |
| Herzberg, L | 1 |
| Farebrother, DA | 1 |
| Hatfield, PJ | 1 |
| Simonds, HA | 1 |
| Cameron, JS | 1 |
| Jones, AS | 1 |
| Cadenhead, A | 1 |
| Miyahara, M | 1 |
| Fujise, Y | 1 |
| Hoshikawa, K | 1 |
| Nakagawa, K | 1 |
| Treadwell, BL | 1 |
| Hohenegger, M | 1 |
| Bresnik, W | 1 |
| Paulus, HE | 1 |
| Coutts, A | 1 |
| Calabro, JJ | 1 |
| Klinenberg, JR | 1 |
| Kantor, GL | 1 |
| Rastogi, SP | 1 |
| Volans, G | 1 |
| Elliott, RW | 1 |
| Eccleston, DW | 1 |
| Ashcroft, R | 1 |
| Webster, D | 1 |
| Kerr, DN | 1 |
| Yu, TF | 1 |
| Berger, L | 1 |
| Gutman, AB | 1 |
| Thomas, J | 1 |
| Thomas, E | 1 |
| Rabussier, H | 1 |
| Desgrez, P | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Alternative Haemodiafiltration in Summer Season for Chronic Kidney Disease Patients[NCT05861219] | 100 participants (Anticipated) | Interventional | 2023-06-21 | Not yet recruiting | |||
| Using of the Skin as a Third Spare Kidney for Patients With Chronic Renal Failure[NCT03810989] | 86 participants (Anticipated) | Interventional | 2019-06-01 | Not yet recruiting | |||
| A Phase II Multidose Study of Intravenous PEG-uricase in Patients With Refractory Gout[NCT00111657] | Phase 2 | 30 participants (Actual) | Interventional | 2004-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of patients who developed antibodies to PEG-uricase (NCT00111657)
Timeframe: baseline, then prior to infusions and 7 wks after last infusion
| Intervention | participants (Number) |
|---|---|
| Pegloticase | 15 |
The highest drug concentration in the blood after the first infusion of study drug. (NCT00111657)
Timeframe: 2 hours
| Intervention | mU/mL (Mean) |
|---|---|
| Single Arm - Pegloticase | 25.6 |
The lowest drug concentration in the blood after the first infusion of study drug. (NCT00111657)
Timeframe: 21 days after the infusion
| Intervention | mU/mL (Mean) |
|---|---|
| Single Arm - Pegloticase | 4.9 |
(NCT00111657)
Timeframe: Baseline to Day 105
| Intervention | Participants (Number) |
|---|---|
| Single Arm | 17 |
Count of tenderness and swelling of 68 joints (NCT00111657)
Timeframe: Basline and day 134
| Intervention | joints (Median) | |||
|---|---|---|---|---|
| Number of Tender joints at baseline | Number of Tender joints at day 134 | Number of Swollen jonts at baseline | Number of Swollen jonts at day 134 | |
| Pegloticase | 13 | 2 | 9 | 6 |
1 review available for urea and Gout
| Article | Year |
|---|---|
[Effects and side-effects of hypotensive diuretics].
Topics: Antihypertensive Agents; Benzothiadiazines; Chlorothiazide; Diabetes Mellitus; Diuretics; Gout; Huma | 1968 |
3 trials available for urea and Gout
| Article | Year |
|---|---|
Acute effect of milk on serum urate concentrations: a randomised controlled crossover trial.
Topics: Adult; Animals; Cross-Over Studies; Gout; Humans; Hypoxanthine; Male; Middle Aged; Milk; Purine Nucl | 2010 |
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase.
Topics: Adult; Aged; Carbon Radioisotopes; Female; Gout; Humans; Hyperuricemia; Immunoglobulin G; Male; Midd | 2006 |
[Benziodarone in hyperuricemia due to renal insufficiency].
Topics: Acute Kidney Injury; Adult; Aged; Allopurinol; Benzofurans; Clinical Trials as Topic; Gout; Humans; | 1973 |
41 other studies available for urea and Gout
| Article | Year |
|---|---|
Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice.
Topics: Age of Onset; Alleles; Animals; Body Weight; Cystatins; Disease Models, Animal; Disease Progression; | 2013 |
The impact of Ramadan fast on patients with gout.
Topics: Adult; Aged; Aged, 80 and over; Allopurinol; Body Mass Index; Case-Control Studies; Colchicine; Crea | 2014 |
Genetic variation in WDR1 is associated with gout risk and gout-related metabolic indices in the Han Chinese population.
Topics: Adult; Case-Control Studies; China; Female; Gout; Humans; Male; Microfilament Proteins; Middle Aged; | 2016 |
Potential of IL-33 for Preventing the Kidney Injury via Regulating the Lipid Metabolism in Gout Patients.
Topics: Adult; Aged; Aged, 80 and over; Creatinine; Female; Gout; Humans; Hypertension; Interleukin-33; Kidn | 2016 |
Relationship between plasma uridine and urinary urea excretion.
Topics: Adult; Creatinine; Diet; Dietary Carbohydrates; Dietary Fats; Dietary Proteins; Gout; Homeostasis; H | 2010 |
Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases.
Topics: Age Factors; Case-Control Studies; Comorbidity; Creatinine; Genetic Variation; Genome-Wide Associati | 2010 |
Uric acid and urea in human sweat.
Topics: Adult; Gout; Humans; Hyperuricemia; Kidney; Male; Middle Aged; Sweat; Urea; Uric Acid | 2002 |
Uric acid and urea in human sweat.
Topics: Adult; Gout; Humans; Hyperuricemia; Kidney; Male; Middle Aged; Sweat; Urea; Uric Acid | 2002 |
Uric acid and urea in human sweat.
Topics: Adult; Gout; Humans; Hyperuricemia; Kidney; Male; Middle Aged; Sweat; Urea; Uric Acid | 2002 |
Uric acid and urea in human sweat.
Topics: Adult; Gout; Humans; Hyperuricemia; Kidney; Male; Middle Aged; Sweat; Urea; Uric Acid | 2002 |
Ammonia, urea and uric acid content of toenails in renal insufficiency and gout.
Topics: Ammonia; Gout; Humans; Kidney Diseases; Nails; Renal Insufficiency; Urea; Uric Acid | 1953 |
[Biological supervision of the gout patient treated with uric acid eliminators with the aid of a simple test: the mean clearance of urea and uric acid].
Topics: Gout; Humans; Kidney Function Tests; Kinetics; Urea; Uric Acid | 1961 |
GOUT AND SALT-WASTING RENAL DISEASE DURING PREGNANCY; DIAGNOSIS, MANAGEMENT, AND FOLLOW-UP.
Topics: Blood Chemical Analysis; Colchicine; Diet Therapy; Diet, Sodium-Restricted; Female; Follow-Up Studie | 1963 |
GOUT, HYPERURICAEMIA AND CARBOHYDRATE METABOLISM.
Topics: Carbohydrate Metabolism; Cholesterol; Glucose Tolerance Test; Gout; Humans; Hypertension; Hyperurice | 1964 |
CLINICAL TRIAL OF TRIAMTERENE IN HYPERTENSIVE PATIENTS.
Topics: Biomedical Research; Blood Chemical Analysis; Blood Pressure Determination; Diuretics; Gout; Hyperal | 1964 |
ONE YEAR'S EXPERIENCE WITH AN INTERMITTENT DIALYSIS PROGRAM.
Topics: Blood Chemical Analysis; Blood Urea Nitrogen; Creatine; Creatinine; Dialysis; Diet; Diet Therapy; Ed | 1964 |
THE RENAL LESION IN GOUT.
Topics: Blood Chemical Analysis; Gout; Histological Techniques; Humans; Kidney; Kidney Diseases; Nephroscler | 1965 |
Association of biochemical values with morbidity in the elderly: a population-based Swedish study of persons aged 82 or more years.
Topics: Aged; Aged, 80 and over; Biomarkers; Blood Chemical Analysis; Body Mass Index; Cholesterol; Creatine | 2003 |
Increased renal excretion of urate in young patients with gout.
Topics: Gout; Humans; Kidney; Renal Elimination; Urea; Uric Acid | 1950 |
Regimen of indomethacin therapy in acute gouty arthritis.
Topics: Adult; Creatine; Female; Gout; Headache; Humans; Indomethacin; Male; Middle Aged; Nausea; Urea; Uric | 1967 |
Effect of prazosin on renal function in chronic congestive cardiac failure.
Topics: Adult; Aged; Body Weight; Creatinine; Gout; Heart Failure; Humans; Kidney; Male; Middle Aged; Prazos | 1981 |
Tienilic acid in the treatment of gout and hypertension.
Topics: Adult; Blood Chemical Analysis; Blood Pressure; Creatinine; Glycolates; Gout; Humans; Hypertension; | 1980 |
Case report: diclofenac-induced rhabdomyolysis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Creatine Kinase; Creatinine; Diclofenac; Erythema Mu | 1996 |
Oral desensitization in patients with chronic tophaceous gout and allopurinol hypersensitivity.
Topics: Administration, Oral; Aged; Allopurinol; Chronic Disease; Desensitization, Immunologic; Drug Hyperse | 1999 |
Diuretic induced gout: a multifactorial condition.
Topics: Aged; Aged, 80 and over; Creatinine; Diuretics; Female; Glomerular Filtration Rate; Gout; Humans; Ki | 1992 |
The "switch-off" mechanism of spontaneous resolution of acute gout attack.
Topics: Acute Disease; Allantoin; Crystallization; Durapatite; Gout; Humans; Hydroxyapatites; Kinetics; Lumi | 1986 |
[Hyperlipoproteinemia in primary gout and asymptomatic hyperuricemia].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cholesterol; Creatinine; Gout; Humans; Hyperlipoproteine | 1988 |
Significance of single serum urate estimations in acutely hospitalized elderly patients.
Topics: Aged; Aged, 80 and over; Arthritis; Diuretics; Female; Gout; Humans; Male; Middle Aged; Predictive V | 1987 |
Withdrawal of allopurinol in patients with gout.
Topics: Adult; Aged; Allopurinol; Female; Gout; Humans; Male; Middle Aged; Recurrence; Substance Withdrawal | 1974 |
The scientific development of clinical chemistry to 1948.
Topics: Albuminuria; Animals; Biochemistry; Blood; Blood Glucose; Chemistry, Clinical; Colorimetry; Edema; E | 1973 |
Management of gout.
Topics: Anti-Inflammatory Agents; Arthritis; Diet; Gout; Humans; Kidney Diseases; Phagocytes; Synovial Fluid | 1972 |
[Normal activity of hypoxanthine-guanine-phosphoribosyl transferase in adults with primary gout].
Topics: Adult; Aged; Creatinine; Erythrocytes; Gout; Guanine; Humans; Hypoxanthines; Male; Middle Aged; Phos | 1973 |
[Comparative pathogenetic studies on osteochondrosis dissecans and idiopathic necrosis of the head of the femur].
Topics: Adult; Embolism, Fat; Fatty Acids; Female; Femur Head Necrosis; Gout; Hip Joint; Humans; Hyperlipide | 1973 |
Familial hyperuricaemia and hypertriglyceridaemia.
Topics: Adolescent; Adult; Alcohol Drinking; Blood Pressure; Cholesterol; Female; Gout; Humans; Hyperlipidem | 1973 |
[Diabetes mellitus, serum urate and gout. A study in 314 patients (author's transl)].
Topics: Adult; Age Factors; Aged; Alloxan; Blood Urea Nitrogen; Diabetes Complications; Diabetes Mellitus; F | 1973 |
Acute intratubular crystal deposition causing permanent renal damage in the pig.
Topics: Allopurinol; Animals; Creatinine; Disease Models, Animal; Duodenum; Gout; Guanine; Kidney; Kidney Ca | 1974 |
Withdrawal of allopurinol in patients with gout.
Topics: Allopurinol; Evaluation Studies as Topic; Follow-Up Studies; Gout; Humans; Male; Middle Aged; Recurr | 1974 |
Juvenile gout.
Topics: Adolescent; Adult; Age Factors; Bacteriuria; Child; Child, Preschool; Creatinine; Female; Gout; Huma | 1971 |
[The daily rhythm of renal uric acid excretion in patients with gout].
Topics: Adult; Calcium; Chlorides; Circadian Rhythm; Creatinine; Gout; Humans; Middle Aged; Natriuresis; Pho | 1969 |
Clinical significance of hyperuricemia in routinely screened hospitalized men.
Topics: Acidosis; Adult; Aged; Autoanalysis; Diuretics; Gout; Heart Failure; Hospitalization; Humans; Kidney | 1970 |
Toxic epidermal necrolysis, azotemia, and death after allopurinol therapy.
Topics: Aged; Allopurinol; Gout; Humans; Male; Mortality; Stevens-Johnson Syndrome; Urea | 1970 |
High dose frusemide in the treatment of hypertension in chronic renal insufficiency and of terminal renal failure.
Topics: Adolescent; Adult; Creatine; Creatinine; Diuresis; Female; Furosemide; Gout; Humans; Hypertension, R | 1971 |
Hypoglycemic and uricosuric properties of acetohexamide and hydroxyhexamide.
Topics: Acetohexamide; Adolescent; Adult; Age Factors; Aged; Blood Glucose; Cyclohexanes; Diabetes Complicat | 1968 |
[Study of pH, of titrable acidity, and urinary buffer system in oxalate lithiasis, in gout and urate lithiasis].
Topics: Gout; Humans; Hydrogen-Ion Concentration; Oxalates; Phosphorus; Urea; Uric Acid; Urinary Calculi | 1968 |