urea has been researched along with Fibrosis in 49 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Fibrosis: Any pathological condition where fibrous connective tissue invades any organ, usually as a consequence of inflammation or other injury.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Hemodynamics, lipid profile, liver enzymes, urea, and creatinine were assessed in conjunction with heart failure markers (serum NT-proANP and cTnI)." | 8.31 | Inhibition of transglutaminase 2 (TG2) ameliorates ventricular fibrosis in isoproterenol-induced heart failure in rats. ( Abusara, S; Al-Dwairi, A; Al-Shboul, O; Al-U'datt, DGF; AlQudah, M; Altuntas, Y; Alu'datt, M; Alzoubi, KH; Hiram, R; Jaradat, S; Tranchant, CC, 2023) |
| " Vinclozolin administration decreased body weight over the treatment period and at the end of the experiment, increased the ratio of kidney weight to body weight and increased serum urea nitrogen and creatinine contents." | 8.12 | Chronic Exposure to Vinclozolin Induced Fibrosis, Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Mice Kidney. ( Cordaro, M; Crupi, R; Cuzzocrea, S; D'Amico, R; Di Paola, D; Di Paola, R; Fusco, R; Genovese, T; Gugliandolo, E; Impellizzeri, D; Interdonato, L; Peritore, AF; Siracusa, R, 2022) |
| "NSO ameliorates sodium nitrite-induced nephrotoxicity through blocking oxidative stress, attenuation of fibrosis/inflammation, restoration of glycogen level, amelioration of cytochrome C oxidase, and inhibition of apoptosis." | 7.83 | Nigella sativa oil attenuates chronic nephrotoxicity induced by oral sodium nitrite: Effects on tissue fibrosis and apoptosis. ( Abbas, A; Al-Gayyar, MM; Alyoussef, A; Darweish, MM; El-Hawwary, AA; Hassan, HM, 2016) |
| "Triclosan (TCS) is a ubiquitous antimicrobial used in daily consumer products." | 5.91 | Adverse effects of triclosan on kidney in mice: Implication of lipid metabolism disorders. ( Cai, Z; Cao, G; Chen, D; Chen, Y; Deng, C; Huang, W; Wang, T, 2023) |
| " Hemodynamics, lipid profile, liver enzymes, urea, and creatinine were assessed in conjunction with heart failure markers (serum NT-proANP and cTnI)." | 4.31 | Inhibition of transglutaminase 2 (TG2) ameliorates ventricular fibrosis in isoproterenol-induced heart failure in rats. ( Abusara, S; Al-Dwairi, A; Al-Shboul, O; Al-U'datt, DGF; AlQudah, M; Altuntas, Y; Alu'datt, M; Alzoubi, KH; Hiram, R; Jaradat, S; Tranchant, CC, 2023) |
| " Vinclozolin administration decreased body weight over the treatment period and at the end of the experiment, increased the ratio of kidney weight to body weight and increased serum urea nitrogen and creatinine contents." | 4.12 | Chronic Exposure to Vinclozolin Induced Fibrosis, Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Mice Kidney. ( Cordaro, M; Crupi, R; Cuzzocrea, S; D'Amico, R; Di Paola, D; Di Paola, R; Fusco, R; Genovese, T; Gugliandolo, E; Impellizzeri, D; Interdonato, L; Peritore, AF; Siracusa, R, 2022) |
| " Adenine treatment reduced body weight, creatinine renal clearance, and increased water intake and urine output, as well as the plasma concentrations of urea and creatinine, neutrophil gelatinase-associated lipocalin, and N-acetyl-β-D-glucosaminidase activity, and albumin in urine." | 3.88 | The effect of sildenafil on rats with adenine-Induced chronic kidney disease. ( Adham, SA; Al Kalbani, J; Al Suleimani, Y; Al Za'abi, M; Ali, BH; Karaca, T; Manoj, P; Nemmar, A; Yasin, J, 2018) |
| "The aim of present study was to investigate the effect of vitamin U (vit U, S-methylmethionine) on oxidative stress, inflammation, and fibrosis within the context of valproic acid (VPA)-induced renal damage." | 3.83 | Vitamin U has a protective effect on valproic acid-induced renal damage due to its anti-oxidant, anti-inflammatory, and anti-fibrotic properties. ( Bolkent, S; Ercin, M; Gezginci-Oktayoglu, S; Turkyilmaz, IB; Yanardag, R, 2016) |
| "NSO ameliorates sodium nitrite-induced nephrotoxicity through blocking oxidative stress, attenuation of fibrosis/inflammation, restoration of glycogen level, amelioration of cytochrome C oxidase, and inhibition of apoptosis." | 3.83 | Nigella sativa oil attenuates chronic nephrotoxicity induced by oral sodium nitrite: Effects on tissue fibrosis and apoptosis. ( Abbas, A; Al-Gayyar, MM; Alyoussef, A; Darweish, MM; El-Hawwary, AA; Hassan, HM, 2016) |
| " Double-knockouts lived 47% longer, mice with 50% DDR1 lived 29% longer and showed improved renal function (reduction in proteinuria and blood urea nitrogen) compared to animals with 100% DDR1 expression." | 3.76 | Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease. ( Beirowski, B; Busse, AC; Girgert, R; Gross, O; Kang, HG; Kretzler, M; Kruegel, J; Miosge, N; Müller, GA; Segerer, S; Vogel, WF; Weber, M, 2010) |
| "Carbamylated proteins formed in renal insufficiency from the spontaneous decomposition of urea exert a variety of metabolic effects." | 3.70 | Carbamylated proteins activate glomerular mesangial cells and stimulate collagen deposition. ( Arruda, JA; Dunea, G; Mo, W; Pegoraro, AA; Shaykh, M; Singh, AK, 1999) |
| "Triclosan (TCS) is a ubiquitous antimicrobial used in daily consumer products." | 1.91 | Adverse effects of triclosan on kidney in mice: Implication of lipid metabolism disorders. ( Cai, Z; Cao, G; Chen, D; Chen, Y; Deng, C; Huang, W; Wang, T, 2023) |
| "(1) Background: Successful treatment of acute kidney injury (AKI)-induced chronic kidney disease (CKD) is unresolved." | 1.56 | Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy: The Involvement of Macrophage Activation. ( Bukosza, EN; Fintha, A; Hamar, P; Kaucsár, T; Krenács, T; Róka, B; Szénási, G; Tod, P, 2020) |
| "Kidney fibrosis is one of the main pathological findings of progressive chronic kidney disease (CKD) although the pathogenesis of renal scar formation remains incompletely explained." | 1.51 | Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression. ( Calleros, L; de Frutos, S; García-Jérez, A; Griera, M; Hatem-Vaquero, M; Luengo, A; O'Valle, F; Rodríguez-Puyol, D; Rodríguez-Puyol, M, 2019) |
| "The development of fibrosis is the most important factor contributing to NASH-associated morbidity and mortality." | 1.48 | Ammonia: A novel target for the treatment of non-alcoholic steatohepatitis. ( Andreola, F; De Chiara, F; Jalan, R; Mookerjee, RP; Rombouts, K; Thomsen, KL; Vilstrup, H, 2018) |
| "Chrysin did not cause any overt adverse effect on the treated rats." | 1.42 | Ameliorative effect of chrysin on adenine-induced chronic kidney disease in rats. ( Adham, SA; Al Za'abi, M; Ali, BH; Nemmar, A; Schupp, N; Waly, MI; Yasin, J, 2015) |
| "Also, in kidneys of ADPKD patients collapsed cysts were observed, in addition to massive fibrosis and immune infiltrates." | 1.39 | Cyst expansion and regression in a mouse model of polycystic kidney disease. ( Breuning, MH; de Heer, E; Happé, H; Leonhard, WN; Peters, DJ; Salvatori, DC; van der Wal, AM, 2013) |
| "Tissue fibrosis is the prominent reason for mortality, and still, there is no satisfactory treatment." | 1.39 | Effectiveness of palosuran in bleomycin-induced experimental scleroderma. ( Bagcı, C; Demir, T; Kaplan, DS; Kisacik, B; Onat, AM; Orkmez, M; Pehlivan, Y; Taysi, S; Turkbeyler, I; Tutar, E, 2013) |
| "In patients with acute liver failure, hyperammonemia is associated with cerebral herniation." | 1.31 | Splanchnic and leg exchange of amino acids and ammonia in acute liver failure. ( Clemmesen, JO; Kondrup, J; Ott, P, 2000) |
| "Probucol is a bisphenolic compound that lowers serum cholesterol and also has potent antioxidant properties." | 1.28 | Effects of probucol in renal function and structure in rats with subtotal kidney ablation. ( Klahr, S; Modi, KS; Purkerson, ML; Schreiner, GF, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (12.24) | 18.2507 |
| 2000's | 8 (16.33) | 29.6817 |
| 2010's | 24 (48.98) | 24.3611 |
| 2020's | 11 (22.45) | 2.80 |
| Authors | Studies |
|---|---|
| Carmona, M | 1 |
| Paco-Meza, LM | 1 |
| Ortega, R | 1 |
| Cañadillas, S | 1 |
| Caballero-Villarraso, J | 1 |
| Blanco, A | 1 |
| Herrera, C | 1 |
| Li, T | 2 |
| Lei, H | 2 |
| Yang, J | 2 |
| Cao, Z | 2 |
| Yang, Y | 1 |
| Liu, Z | 1 |
| Sun, R | 1 |
| Yang, X | 1 |
| Zhai, X | 2 |
| You, D | 1 |
| Weng, M | 1 |
| Wu, X | 1 |
| Nie, K | 1 |
| Cui, J | 1 |
| Chen, Y | 3 |
| Yang, L | 1 |
| Wan, J | 1 |
| Huang, W | 1 |
| Cao, G | 1 |
| Deng, C | 1 |
| Wang, T | 1 |
| Chen, D | 1 |
| Cai, Z | 1 |
| Di Paola, D | 1 |
| D'Amico, R | 1 |
| Genovese, T | 1 |
| Siracusa, R | 1 |
| Cordaro, M | 1 |
| Crupi, R | 1 |
| Peritore, AF | 1 |
| Gugliandolo, E | 1 |
| Interdonato, L | 1 |
| Impellizzeri, D | 1 |
| Fusco, R | 1 |
| Cuzzocrea, S | 1 |
| Di Paola, R | 1 |
| Wang, H | 2 |
| Jiang, Q | 2 |
| Kang, L | 2 |
| Yuan, L | 2 |
| Chen, G | 2 |
| Cui, X | 2 |
| Wang, L | 4 |
| Zhang, T | 2 |
| Al-U'datt, DGF | 1 |
| Tranchant, CC | 1 |
| Alu'datt, M | 1 |
| Abusara, S | 1 |
| Al-Dwairi, A | 1 |
| AlQudah, M | 1 |
| Al-Shboul, O | 1 |
| Hiram, R | 1 |
| Altuntas, Y | 1 |
| Jaradat, S | 1 |
| Alzoubi, KH | 1 |
| Zhu, Y | 2 |
| Yu, C | 1 |
| Zhuang, S | 1 |
| Kuma, A | 1 |
| Wang, XH | 1 |
| Klein, JD | 1 |
| Tan, L | 1 |
| Naqvi, N | 1 |
| Rianto, F | 1 |
| Huang, Y | 1 |
| Yu, M | 1 |
| Sands, JM | 1 |
| Tod, P | 1 |
| Bukosza, EN | 1 |
| Róka, B | 1 |
| Kaucsár, T | 1 |
| Fintha, A | 1 |
| Krenács, T | 1 |
| Szénási, G | 1 |
| Hamar, P | 1 |
| Cui, Y | 1 |
| Wang, X | 1 |
| Wu, H | 1 |
| Saito, T | 1 |
| Uchiumi, T | 1 |
| Yagi, M | 1 |
| Amamoto, R | 1 |
| Setoyama, D | 1 |
| Matsushima, Y | 1 |
| Kang, D | 1 |
| Talebpour Amiri, F | 1 |
| Hamzeh, M | 1 |
| Naeimi, RA | 1 |
| Ghasemi, A | 1 |
| Hosseinimehr, SJ | 1 |
| Thomsen, KL | 1 |
| De Chiara, F | 1 |
| Rombouts, K | 1 |
| Vilstrup, H | 1 |
| Andreola, F | 1 |
| Mookerjee, RP | 1 |
| Jalan, R | 1 |
| Hosseinian, S | 1 |
| Ebrahimzadeh Bideskan, A | 1 |
| Shafei, MN | 1 |
| Sadeghnia, HR | 1 |
| Soukhtanloo, M | 1 |
| Shahraki, S | 1 |
| Samadi Noshahr, Z | 1 |
| Khajavi Rad, A | 1 |
| Chaturvedi, S | 1 |
| Misra, DP | 1 |
| Prasad, N | 1 |
| Rastogi, K | 1 |
| Singh, H | 1 |
| Rai, MK | 1 |
| Agarwal, V | 1 |
| Ali, BH | 2 |
| Al Za'abi, M | 2 |
| Adham, SA | 2 |
| Al Suleimani, Y | 1 |
| Karaca, T | 1 |
| Manoj, P | 1 |
| Al Kalbani, J | 1 |
| Yasin, J | 2 |
| Nemmar, A | 2 |
| de Frutos, S | 1 |
| Luengo, A | 1 |
| García-Jérez, A | 1 |
| Hatem-Vaquero, M | 1 |
| Griera, M | 1 |
| O'Valle, F | 1 |
| Rodríguez-Puyol, M | 1 |
| Rodríguez-Puyol, D | 1 |
| Calleros, L | 1 |
| Happé, H | 1 |
| van der Wal, AM | 1 |
| Salvatori, DC | 1 |
| Leonhard, WN | 1 |
| Breuning, MH | 1 |
| de Heer, E | 1 |
| Peters, DJ | 1 |
| Bian, X | 1 |
| Zhang, B | 1 |
| Guo, W | 1 |
| Liu, N | 1 |
| Bai, Y | 1 |
| Miao, J | 1 |
| Zhao, G | 1 |
| Liu, B | 1 |
| Wang, S | 1 |
| Ma, L | 1 |
| Zheng, L | 1 |
| Zhao, Y | 1 |
| Li, D | 1 |
| Feng, J | 1 |
| Zhang, L | 1 |
| Zhang, D | 1 |
| Zhang, J | 1 |
| Tian, Y | 1 |
| Kim, J | 1 |
| Imig, JD | 1 |
| Hammock, BD | 1 |
| Padanilam, BJ | 1 |
| Singh, S | 1 |
| Suresh, S | 1 |
| McClave, SA | 1 |
| Cave, M | 1 |
| Gezginci-Oktayoglu, S | 1 |
| Turkyilmaz, IB | 1 |
| Ercin, M | 1 |
| Yanardag, R | 1 |
| Bolkent, S | 1 |
| Waly, MI | 1 |
| Schupp, N | 1 |
| Al-Gayyar, MM | 1 |
| Hassan, HM | 1 |
| Alyoussef, A | 1 |
| Abbas, A | 1 |
| Darweish, MM | 1 |
| El-Hawwary, AA | 1 |
| Spronk, HM | 1 |
| De Jong, AM | 1 |
| Verheule, S | 1 |
| De Boer, HC | 1 |
| Maass, AH | 1 |
| Lau, DH | 1 |
| Rienstra, M | 1 |
| van Hunnik, A | 1 |
| Kuiper, M | 1 |
| Lumeij, S | 1 |
| Zeemering, S | 1 |
| Linz, D | 1 |
| Kamphuisen, PW | 1 |
| Ten Cate, H | 1 |
| Crijns, HJ | 1 |
| Van Gelder, IC | 1 |
| van Zonneveld, AJ | 1 |
| Schotten, U | 1 |
| Mazumder, MK | 1 |
| Giri, A | 1 |
| Kumar, S | 1 |
| Borah, A | 1 |
| Abdel-Daim, MM | 1 |
| El-Sayed, YS | 1 |
| Eldaim, MA | 1 |
| Ibrahim, A | 1 |
| Artunc, F | 1 |
| Nasir, O | 1 |
| Amann, K | 1 |
| Boini, KM | 1 |
| Häring, HU | 1 |
| Risler, T | 1 |
| Lang, F | 1 |
| Simolin, MA | 1 |
| Pedersen, TX | 1 |
| Bro, S | 1 |
| Mäyränpää, MI | 1 |
| Helske, S | 1 |
| Nielsen, LB | 1 |
| Kovanen, PT | 1 |
| Gross, O | 1 |
| Girgert, R | 1 |
| Beirowski, B | 1 |
| Kretzler, M | 1 |
| Kang, HG | 1 |
| Kruegel, J | 1 |
| Miosge, N | 1 |
| Busse, AC | 1 |
| Segerer, S | 1 |
| Vogel, WF | 1 |
| Müller, GA | 2 |
| Weber, M | 1 |
| Caliskan, B | 1 |
| Guven, A | 1 |
| Ozler, M | 1 |
| Cayci, T | 1 |
| Ozcan, A | 1 |
| Bedir, O | 1 |
| Surer, I | 1 |
| Korkmaz, A | 1 |
| Balarini, CM | 1 |
| Oliveira, MZ | 1 |
| Pereira, TM | 1 |
| Silva, NF | 1 |
| Vasquez, EC | 1 |
| Meyrelles, SS | 1 |
| Gava, AL | 1 |
| Hale, TM | 1 |
| Robertson, SJ | 1 |
| Burns, KD | 1 |
| deBlois, D | 1 |
| Demir, T | 1 |
| Turkbeyler, I | 1 |
| Kaplan, DS | 1 |
| Pehlivan, Y | 1 |
| Orkmez, M | 1 |
| Tutar, E | 1 |
| Taysi, S | 1 |
| Kisacik, B | 1 |
| Onat, AM | 1 |
| Bagcı, C | 1 |
| Thomas, A | 1 |
| Klein, MS | 1 |
| Stevens, AP | 1 |
| Reinders, Y | 1 |
| Hellerbrand, C | 1 |
| Dettmer, K | 1 |
| Gronwald, W | 1 |
| Oefner, PJ | 1 |
| Reinders, J | 1 |
| De Vriese, AS | 1 |
| Flyvbjerg, A | 1 |
| Mortier, S | 1 |
| Tilton, RG | 1 |
| Lameire, NH | 1 |
| Briscoe, TA | 1 |
| Rehn, AE | 1 |
| Dieni, S | 1 |
| Duncan, JR | 1 |
| Wlodek, ME | 1 |
| Owens, JA | 1 |
| Rees, SM | 1 |
| Soria, F | 1 |
| Sun, F | 1 |
| Durán, E | 1 |
| Sánchez, FM | 1 |
| Usón, J | 1 |
| Krämer, S | 1 |
| Wang-Rosenke, Y | 1 |
| Scholl, V | 1 |
| Binder, E | 1 |
| Loof, T | 1 |
| Khadzhynov, D | 1 |
| Kawachi, H | 1 |
| Shimizu, F | 1 |
| Diekmann, F | 1 |
| Budde, K | 1 |
| Neumayer, HH | 1 |
| Peters, H | 1 |
| Battle, T | 1 |
| Schnell, C | 1 |
| Bunkenburg, B | 1 |
| Heudes, D | 1 |
| Wood, JM | 1 |
| Ménard, J | 1 |
| Wieczorowska, K | 1 |
| Khanna, R | 1 |
| Moore, HL | 1 |
| Nolph, KD | 1 |
| Twardowski, ZJ | 1 |
| Lemière, C | 1 |
| Malo, JL | 1 |
| Garbe-Galanti, L | 1 |
| Shaykh, M | 1 |
| Pegoraro, AA | 1 |
| Mo, W | 1 |
| Arruda, JA | 1 |
| Dunea, G | 1 |
| Singh, AK | 1 |
| Sommer, M | 1 |
| Schaller, R | 1 |
| Fünfstück, R | 1 |
| Bohle, A | 1 |
| Böhmer, FD | 1 |
| Stein, G | 1 |
| Clemmesen, JO | 1 |
| Kondrup, J | 1 |
| Ott, P | 1 |
| George, J | 1 |
| Chandrakasan, G | 1 |
| Modi, KS | 1 |
| Schreiner, GF | 1 |
| Purkerson, ML | 1 |
| Klahr, S | 1 |
1 review available for urea and Fibrosis
| Article | Year |
|---|---|
Treating Every Needle in the Haystack: Hyperammonemic Encephalopathy and Severe Malnutrition After Bariatric Surgery-A Case Report and Review of the Literature.
Topics: Adult; Ammonia; Brain Diseases, Metabolic; Diagnostic Errors; Female; Fibrosis; Gastric Bypass; Huma | 2015 |
48 other studies available for urea and Fibrosis
| Article | Year |
|---|---|
Hypoxia preconditioning increases the ability of healthy but not diabetic rat-derived adipose stromal/stem cells (ASC) to improve histological lesions of streptozotocin-induced diabetic nephropathy.
Topics: Adipose Tissue; Albuminuria; Animals; Blood Glucose; Cell Hypoxia; Cell Proliferation; Cells, Cultur | 2022 |
Hybrid imidazo[1,2-a]pyridine analogs as potent ATX inhibitors with concrete in vivo antifibrosis effect.
Topics: Bleomycin; Carbamates; Fibrosis; Humans; Phosphoric Diester Hydrolases; Pyridines; Structure-Activit | 2022 |
C3aR contributes to unilateral ureteral obstruction-induced renal interstitial fibrosis via the activation of the NLRP3 inflammasome.
Topics: Animals; Complement C3a; Creatinine; DNA Nucleotidylexotransferase; Eosine Yellowish-(YS); Fibrosis; | 2022 |
Adverse effects of triclosan on kidney in mice: Implication of lipid metabolism disorders.
Topics: Animals; Anti-Infective Agents; Corn Oil; Creatinine; Cytokines; Dimethyl Sulfoxide; Fatty Acids; Fi | 2023 |
Chronic Exposure to Vinclozolin Induced Fibrosis, Mitochondrial Dysfunction, Oxidative Stress, and Apoptosis in Mice Kidney.
Topics: Animals; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Body Weight; Caspase 3; Catalase; Crea | 2022 |
Rheum officinale and Salvia miltiorrhiza inhibit renal fibrosis via miR-21/PTEN/Akt signaling pathway in vitro and in vivo.
Topics: Animals; Creatinine; Fibrosis; Humans; Kidney Diseases; MicroRNAs; Proto-Oncogene Proteins c-akt; PT | 2023 |
Rheum officinale and Salvia miltiorrhiza inhibit renal fibrosis via miR-21/PTEN/Akt signaling pathway in vitro and in vivo.
Topics: Animals; Creatinine; Fibrosis; Humans; Kidney Diseases; MicroRNAs; Proto-Oncogene Proteins c-akt; PT | 2023 |
Rheum officinale and Salvia miltiorrhiza inhibit renal fibrosis via miR-21/PTEN/Akt signaling pathway in vitro and in vivo.
Topics: Animals; Creatinine; Fibrosis; Humans; Kidney Diseases; MicroRNAs; Proto-Oncogene Proteins c-akt; PT | 2023 |
Rheum officinale and Salvia miltiorrhiza inhibit renal fibrosis via miR-21/PTEN/Akt signaling pathway in vitro and in vivo.
Topics: Animals; Creatinine; Fibrosis; Humans; Kidney Diseases; MicroRNAs; Proto-Oncogene Proteins c-akt; PT | 2023 |
Inhibition of transglutaminase 2 (TG2) ameliorates ventricular fibrosis in isoproterenol-induced heart failure in rats.
Topics: Animals; Chromatography, Liquid; Collagen; Creatinine; Cystamine; Fibrosis; Heart Failure; Isoproter | 2023 |
Protein arginine methyltransferase 1 mediates renal fibroblast activation and fibrogenesis through activation of Smad3 signaling.
Topics: Animals; Cell Dedifferentiation; Cell Line; Cell Proliferation; Disease Models, Animal; Enzyme Inhib | 2020 |
Inhibition of urea transporter ameliorates uremic cardiomyopathy in chronic kidney disease.
Topics: Actins; Animals; Cardiomegaly; Cardiomyopathies; Fibrosis; Heart Ventricles; Hypertension; Kidney; M | 2020 |
Post-Ischemic Renal Fibrosis Progression Is Halted by Delayed Contralateral Nephrectomy: The Involvement of Macrophage Activation.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Chemokine CCL2; Disease Progression; Fibrosis; In | 2020 |
Design, synthesis and anti-fibrosis evaluation of imidazo[1,2-a]pyridine derivatives as potent ATX inhibitors.
Topics: Animals; Antifibrotic Agents; Dose-Response Relationship, Drug; Drug Design; Fibrosis; Humans; Male; | 2021 |
Cardiomyocyte-specific loss of mitochondrial p32/C1qbp causes cardiomyopathy and activates stress responses.
Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinases; Animals; Cardiomyopathies; Carr | 2017 |
Radioprotective effect of atorvastatin against ionizing radiation-induced nephrotoxicity in mice.
Topics: Animals; Apoptosis; Atorvastatin; Caspase 3; Creatinine; Disease Models, Animal; Fibrosis; Hydroxyme | 2018 |
Ammonia: A novel target for the treatment of non-alcoholic steatohepatitis.
Topics: Ammonia; Animals; Biopsy; Disease Models, Animal; Disease Progression; Fibrosis; Hepatic Stellate Ce | 2018 |
Nigella sativa extract is a potent therapeutic agent for renal inflammation, apoptosis, and oxidative stress in a rat model of unilateral ureteral obstruction.
Topics: Angiotensin II; Animals; Apoptosis; Captopril; Chemokine CCL2; Creatinine; Fibrosis; Inflammation; K | 2018 |
5-HT
Topics: Adult; Cells, Cultured; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; F | 2018 |
The effect of sildenafil on rats with adenine-Induced chronic kidney disease.
Topics: Adenine; Animals; Biomarkers; Blood Pressure; Body Weight; Creatinine; Cytokines; Fibrosis; Inflamma | 2018 |
Chronic kidney disease induced by an adenine rich diet upregulates integrin linked kinase (ILK) and its depletion prevents the disease progression.
Topics: Actins; Adenine; Animals; Cadherins; Creatinine; Diet; Disease Models, Animal; Extracellular Matrix; | 2019 |
Cyst expansion and regression in a mouse model of polycystic kidney disease.
Topics: Age Factors; Animals; Biomarkers; Disease Models, Animal; Disease Progression; Extracellular Matrix; | 2013 |
Effects of mesenchymal stem cells transplanted at different time points in a rat remnant kidney model.
Topics: Actins; Animals; Cell Movement; Creatinine; Fibrosis; Glomerular Filtration Rate; Glomerulosclerosis | 2014 |
Platelet factor 4 protects kidney allograft in a rat kidney transplantation model.
Topics: Allografts; Animals; Cell Differentiation; Cells, Cultured; Creatinine; Fibrosis; Graft Rejection; I | 2015 |
Inhibition of soluble epoxide hydrolase prevents renal interstitial fibrosis and inflammation.
Topics: Animals; Apoptosis; Benzoates; Epoxide Hydrolases; Fibrosis; Kidney; Kidney Diseases; Male; Mice, In | 2014 |
Vitamin U has a protective effect on valproic acid-induced renal damage due to its anti-oxidant, anti-inflammatory, and anti-fibrotic properties.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blotting, Western; Catalase; Collagen Type I; Creat | 2016 |
Ameliorative effect of chrysin on adenine-induced chronic kidney disease in rats.
Topics: Acetylglucosaminidase; Adenine; Animals; Antioxidants; Creatinine; Disease Models, Animal; Fibrosis; | 2015 |
Nigella sativa oil attenuates chronic nephrotoxicity induced by oral sodium nitrite: Effects on tissue fibrosis and apoptosis.
Topics: Animals; Antioxidants; Apoptosis; C-Reactive Protein; Caspase 3; Chemokine CCL2; Creatinine; Fibrosi | 2016 |
Hypercoagulability causes atrial fibrosis and promotes atrial fibrillation.
Topics: Analysis of Variance; Animals; Antithrombins; Atrial Fibrillation; Cell Proliferation; Dabigatran; F | 2017 |
A highly reproducible mice model of chronic kidney disease: Evidences of behavioural abnormalities and blood-brain barrier disruption.
Topics: Adenine; Animals; Behavior, Animal; Blood-Brain Barrier; Brain; Creatinine; Diet; Disease Models, An | 2016 |
Nephroprotective efficacy of ceftriaxone against cisplatin-induced subchronic renal fibrosis in rats.
Topics: Actins; Animals; Biomarkers; Bromodeoxyuridine; Ceftriaxone; Cell Proliferation; Cisplatin; Creatini | 2017 |
Serum- and glucocorticoid-inducible kinase 1 in doxorubicin-induced nephrotic syndrome.
Topics: Albuminuria; Animals; Body Weight; Doxorubicin; Fibrosis; Immediate-Early Proteins; Mice; Mice, Inbr | 2008 |
ACE inhibition attenuates uremia-induced aortic valve thickening in a novel mouse model.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve; Aortic Valve Stenosis; Apolipoprote | 2009 |
Loss of collagen-receptor DDR1 delays renal fibrosis in hereditary type IV collagen disease.
Topics: Animals; CD3 Complex; Collagen Type IV; Connective Tissue Growth Factor; Discoidin Domain Receptor 1 | 2010 |
Ozone therapy prevents renal inflammation and fibrosis in a rat model of acute pyelonephritis.
Topics: Acute Disease; Animals; Anti-Bacterial Agents; Aspartate Aminotransferases; Calcitonin; Ciprofloxaci | 2011 |
Hypercholesterolemia promotes early renal dysfunction in apolipoprotein E-deficient mice.
Topics: Age Factors; Animals; Apolipoproteins E; Fibrosis; Gene Expression; Glomerular Filtration Rate; Hype | 2011 |
Short-term ACE inhibition confers long-term protection against target organ damage.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Cell Proliferation; Creatinine; D | 2012 |
Effectiveness of palosuran in bleomycin-induced experimental scleroderma.
Topics: Animals; Bleomycin; Endothelin-1; Extracellular Matrix; Fibrosis; Male; Mice; Mice, Inbred BALB C; Q | 2013 |
Changes in the hepatic mitochondrial and membrane proteome in mice fed a non-alcoholic steatohepatitis inducing diet.
Topics: Animals; Cations; Cell Membrane; Cholesterol; Diet; Disease Models, Animal; Electrophoresis, Gel, Tw | 2013 |
Inhibition of the interaction of AGE-RAGE prevents hyperglycemia-induced fibrosis of the peritoneal membrane.
Topics: Albumins; Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Biological Transport; Diabetes Mellit | 2003 |
Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency.
Topics: Adrenal Glands; Animals; Aorta; Arteries; Body Weight; Cardiovascular Diseases; Chlorides; Chronic D | 2004 |
Metallic ureteral stents versus endoureterotomy as a therapeutic approach for experimental ureteral stricture.
Topics: Animals; Bacteriuria; Catheterization; Constriction, Pathologic; Creatinine; Disease Models, Animal; | 2005 |
Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat.
Topics: Animals; Blood Pressure; Body Weight; Cell Movement; Cell Proliferation; Collagen Type I; Creatinine | 2008 |
Continuous versus intermittent angiotensin converting enzyme inhibition in renal hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Cre | 1993 |
Rat model of peritoneal fibrosis: preliminary observations.
Topics: Animals; Blood Urea Nitrogen; Escherichia coli Infections; Fibrosis; Glucose; Male; Peritoneal Dialy | 1995 |
[Bronchial irritation syndrome following inhalation or urea. Histologic and immunohistochemical evaluation].
Topics: Adult; Air Pollutants, Occupational; Biopsy; Bronchial Diseases; Bronchial Hyperreactivity; Bronchoa | 1996 |
Carbamylated proteins activate glomerular mesangial cells and stimulate collagen deposition.
Topics: Animals; Cattle; Cell Division; Cells, Cultured; Collagen; Cyanates; Fetal Blood; Fibrosis; Gelatina | 1999 |
Abnormal growth and clonal proliferation of fibroblasts in an animal model of unilateral ureteral obstruction.
Topics: Animals; Cell Division; Cells, Cultured; Collagen; Collagenases; Creatinine; Disease Models, Animal; | 1999 |
Splanchnic and leg exchange of amino acids and ammonia in acute liver failure.
Topics: Adult; Alanine; Amino Acids; Ammonia; Blood Urea Nitrogen; Citrulline; Female; Femoral Artery; Femor | 2000 |
Biochemical abnormalities during the progression of hepatic fibrosis induced by dimethylnitrosamine.
Topics: Animals; Blood Glucose; Cholesterol; Creatinine; Dimethylnitrosamine; Fibrosis; Hydroxyproline; Insu | 2000 |
Effects of probucol in renal function and structure in rats with subtotal kidney ablation.
Topics: Animals; Atrophy; Blood Pressure; Body Weight; Cholesterol; Female; Fibrosis; Hematocrit; Kidney; Ki | 1992 |