Page last updated: 2024-10-21

urea and Experimental Mammary Neoplasms

urea has been researched along with Experimental Mammary Neoplasms in 30 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Research Excerpts

ExcerptRelevanceReference
"Thirty-five inbred female Sprague Dawley rats aged 43 days were administered with three weekly doses of N-methyl-N-nitrosourea (NMU) intraperitoneally (ip) at 50 mg/kg body weight."3.80Correlation of tumour response with starting tumour size and dose of tamoxifen in an N-methyl-N-nitrosourea (NMU)-induced rat mammary cancer model. ( Emilia, ST; Shaari, R; Yaacob, NS; Yankuzo, HM, 2014)
" Our aim was to assess the effects of the natural zeolite, clinoptilolite, on hematopoiesis, serum electrolytes and essential biochemical indicators of kidney and liver function in mice."3.71The effect of the zeolite clinoptilolite on serum chemistry and hematopoiesis in mice. ( Boranic, M; Breljak, D; Flegar-Mestric, Z; Martin-Kleiner, I; Marusic, M; Radacic, M; Stanovic Janda, S; Stojkovic, R; Zadro, R, 2001)
"Urea appears to be a useful low molecular weight relative recovery marker for tumor microdialysis."1.31Urea as a recovery marker for quantitative assessment of tumor interstitial solutes with microdialysis. ( Dewhirst, MW; Ettinger, SN; Gaskin, AA; Klitzman, B; Poellmann, CC; Poulson, JM; Shoemaker, JS; Wisniewski, NA, 2001)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-199020 (66.67)18.7374
1990's0 (0.00)18.2507
2000's4 (13.33)29.6817
2010's5 (16.67)24.3611
2020's1 (3.33)2.80

Authors

AuthorsStudies
Jin, L1
Wang, Y1
Ouyang, H1
Liu, Y1
Zhu, Z1
Wang, S1
Xin, H1
Wang, X1
Kelderhouse, LE1
Chelvam, V1
Wayua, C1
Mahalingam, S1
Poh, S1
Kularatne, SA1
Low, PS1
Portilho, FA1
Cavalcanti, CE1
Miranda-Vilela, AL1
Estevanato, LL1
Longo, JP1
Almeida Santos, Mde F1
Bocca, AL1
Martins, OP1
Simioni, AR1
Morais, PC1
Azevedo, RB1
Tedesco, AC1
Lacava, ZG1
Yankuzo, HM1
Emilia, ST1
Shaari, R1
Yaacob, NS1
Pacchiano, F1
Carta, F1
McDonald, PC1
Lou, Y1
Vullo, D1
Scozzafava, A1
Dedhar, S1
Supuran, CT1
Patel, RA1
Forinash, KD1
Pireddu, R1
Sun, Y1
Sun, N1
Martin, MP1
Schönbrunn, E1
Lawrence, NJ1
Sebti, SM1
Gable, KL1
Maddux, BA1
Penaranda, C1
Zavodovskaya, M1
Campbell, MJ1
Lobo, M1
Robinson, L1
Schow, S1
Kerner, JA1
Goldfine, ID1
Youngren, JF1
Jobst, K1
Vaage, J1
Anderson, B1
Chu, A1
Hicks, KO1
Pruijn, FB1
Baguley, BC1
Wilson, WR1
Martin-Kleiner, I1
Flegar-Mestric, Z1
Zadro, R1
Breljak, D1
Stanovic Janda, S1
Stojkovic, R1
Marusic, M1
Radacic, M1
Boranic, M1
Ettinger, SN1
Poellmann, CC1
Wisniewski, NA1
Gaskin, AA1
Shoemaker, JS1
Poulson, JM1
Dewhirst, MW1
Klitzman, B1
Powell, BL1
Hollander, VP1
Teller, MN1
Stock, CC1
Hellman, L1
Mountain, IM1
Bowie, M1
Rosenberg, BJ1
Boyar, RM1
Budinger, JM1
Koestner, A1
Denlinger, RH1
Amber, IJ1
Hibbs, JB1
Taintor, RR1
Vavrin, Z1
Laverick, M2
Gordon, M2
Kind, PR2
Slavin, BM2
Nias, AH2
Terracini, B1
Testa, MC1
Schreiber, D1
Warzok, R1
Scholtze, P1
Schneider, J1
Lageman, A1
Batka, H1
Korytnyk, W1
Ghosh, AC1
Angelino, N1
Dave, C1
Takizawa, S3
Nishihara, H2
Hosokawa, M1
Gotoda, E1
Kobayashi, H1
Yamasaki, T1
Yokoro, K1
Imamura, N1
Nishihara, E1
Kelly, MG1
O'Gara, RW1
Yancey, ST1
Botkin, C1
Marytnova, RP1
Ronichevskaia, GM1
Sekirov, BA1
Alexandrov, VA1
Hilf, R1
Bell, C1
Michel, I1
Freeman, JJ1
Borman, A1
Lerner, LJ1
Bianchi, A1
Dzelzkalns, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
An Open-label, Multi-center, Phase 1b Study to Investigate the Safety and Tolerability of SLC-0111 (WBI-5111) in Combination With Gemcitabine in Metastatic Pancreatic Ductal Adenocarcinoma Subjects Positive for Carbonic Anhydrase IX[NCT03450018]Phase 1/Phase 230 participants (Anticipated)Interventional2019-01-10Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for urea and Experimental Mammary Neoplasms

ArticleYear
Comparative effects of a series of prolactin inhibitors, 17beta-estradiol and 2alpha-methyldihydrotestosterone propionate, on growth of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinomas.
    Cancer research, 1977, Volume: 37, Issue:11

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Acetonitriles; Androstanols; Animals; Breast Neoplasms; Bromocript

1977

Other Studies

29 other studies available for urea and Experimental Mammary Neoplasms

ArticleYear
A versatile and low-toxicity material for photothermal therapy in deeper tissues.
    Journal of materials chemistry. B, 2021, 08-21, Volume: 9, Issue:31

    Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Cell Proliferation; Cell Survival; Drug Scr

2021
Development of tumor-targeted near infrared probes for fluorescence guided surgery.
    Bioconjugate chemistry, 2013, Jun-19, Volume: 24, Issue:6

    Topics: Animals; Female; Fluorescence; Fluorescent Dyes; Folic Acid; Glutarates; Humans; Infrared Rays; KB C

2013
Antitumor activity of photodynamic therapy performed with nanospheres containing zinc-phthalocyanine.
    Journal of nanobiotechnology, 2013, Dec-16, Volume: 11

    Topics: Alanine Transaminase; Albumins; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Bilirubi

2013
Correlation of tumour response with starting tumour size and dose of tamoxifen in an N-methyl-N-nitrosourea (NMU)-induced rat mammary cancer model.
    Asian Pacific journal of cancer prevention : APJCP, 2014, Volume: 15, Issue:16

    Topics: Animals; Body Weight; Creatinine; Drug Dosage Calculations; Female; Mammary Neoplasms, Experimental;

2014
Ureido-substituted benzenesulfonamides potently inhibit carbonic anhydrase IX and show antimetastatic activity in a model of breast cancer metastasis.
    Journal of medicinal chemistry, 2011, Mar-24, Volume: 54, Issue:6

    Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Benzene Derivatives; Carbonic Anhydrase IX; Carb

2011
RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer.
    Cancer research, 2012, Oct-01, Volume: 72, Issue:19

    Topics: Animals; Antineoplastic Agents; Binding Sites; Blotting, Western; Breast Neoplasms; Cell Line, Tumor

2012
Diarylureas are small-molecule inhibitors of insulin-like growth factor I receptor signaling and breast cancer cell growth.
    Molecular cancer therapeutics, 2006, Volume: 5, Issue:4

    Topics: Aminoquinolines; Animals; Animals, Genetically Modified; Antineoplastic Agents; Apoptosis; Breast Ne

2006
Teratogenous changes and tumors in rats following treatment with methylnitroso-urea (MNU).
    Neoplasma, 1967, Volume: 14, Issue:4

    Topics: Animals; Brain; Bronchial Neoplasms; Carcinogens; Female; Kidney Neoplasms; Male; Mammary Neoplasms,

1967
Excretion of carcinoma products in irradiated C3H/He mice.
    Cancer research, 1981, Volume: 41, Issue:2

    Topics: Animals; Ascites; Creatinine; Dose-Response Relationship, Radiation; Female; Kidney; Male; Mammary N

1981
Extravascular transport of the DNA intercalator and topoisomerase poison N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide (DACA): diffusion and metabolism in multicellular layers of tumor cells.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 297, Issue:3

    Topics: Acridines; Animals; Antineoplastic Agents; Area Under Curve; Biological Transport; Body Fluid Compar

2001
The effect of the zeolite clinoptilolite on serum chemistry and hematopoiesis in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2001, Volume: 39, Issue:7

    Topics: Administration, Oral; Adsorption; Animals; Blood Cell Count; Body Weight; Creatinine; Electrolytes;

2001
Urea as a recovery marker for quantitative assessment of tumor interstitial solutes with microdialysis.
    Cancer research, 2001, Nov-01, Volume: 61, Issue:21

    Topics: Adenocarcinoma; Animals; Biomarkers, Tumor; Blood Glucose; Extracellular Space; Female; Glucose; Hyp

2001
Studies on the dissociation of prolactin from mammary tumor membranes.
    Endocrinology, 1978, Volume: 103, Issue:3

    Topics: Animals; Female; Mammary Neoplasms, Experimental; Membranes; Prolactin; Rats; Receptors, Cell Surfac

1978
Induction of neurogenic and lymphoid neoplasms by the feeding of threshold levels of methyl- and ethylnitrousourea precursors to adult rats.
    Food and cosmetics toxicology, 1975, Volume: 13, Issue:6

    Topics: Animals; Brain Neoplasms; Ethylnitrosourea; Female; Lymphoma; Mammary Neoplasms, Experimental; Methy

1975
Cytokines induce an L-arginine-dependent effector system in nonmacrophage cells.
    Journal of leukocyte biology, 1988, Volume: 44, Issue:1

    Topics: Animals; Arginine; Biological Products; Citrulline; Cytokines; Humans; Lipopolysaccharides; Mammary

1988
Evaluation of the biochemical effects of CHIP in normal and tumour-bearing C3H mice.
    British journal of cancer, 1986, Volume: 53, Issue:6

    Topics: Acetylglucosaminidase; Alkaline Phosphatase; Animals; Cisplatin; Creatinine; Dose-Response Relations

1986
The effect of C3H mouse mammary tumour on the levels of serum and urine analytes in vivo.
    British journal of cancer, 1985, Volume: 52, Issue:4

    Topics: Acetylglucosaminidase; Aging; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotr

1985
Carcinogenicity of a single administration of N-nitrosomethylurea: a comparison between newborn and 5-week-old mice and rats.
    British journal of cancer, 1970, Volume: 24, Issue:3

    Topics: Adenoma; Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellular; Female; Gastrointestinal

1970
[The spectrum of extra neural tumors in rats following N-methyl-N-nitroso urea treatment].
    Zentralblatt fur allgemeine Pathologie u. pathologische Anatomie, 1972, Volume: 115, Issue:1

    Topics: Abdominal Neoplasms; Animals; Castration; Female; Heart Neoplasms; Hypoxia; Injections, Intraperiton

1972
Guanylhydrazones with potential antileukemic activity. 1. Aza analogs of 4,4'-diacetyldiphenylurea bis(guanylhydrazone).
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Aza Compounds; DNA Nucleotidyltransferases; DNA, Neo

1973
Induction of tumors in the brain, kidney, and other extra-mammary gland organs by a continuous oral administration of N-nitrosobutylurea in Wistar-Furth rats.
    Gan, 1971, Volume: 62, Issue:6

    Topics: Administration, Oral; Animals; Brain Neoplasms; Carcinogens; Castration; Duodenal Neoplasms; Ear Neo

1971
Leukemia and mammary tumor in rats administered N-nitrosobutylurea.
    Gan, 1971, Volume: 62, Issue:6

    Topics: Administration, Oral; Animals; Carcinogens; Female; Leukemia; Male; Mammary Neoplasms, Experimental;

1971
Role of ovarian hormones in mammary tumorigenesis by a continuous oral administration of N-nitrosobutylurea in Wistar-Furth rats.
    Gan, 1971, Volume: 62, Issue:6

    Topics: Adenocarcinoma; Administration, Oral; Animals; Body Weight; Carcinogens; Castration; Estradiol; Estr

1971
Leukemogenic and mammary tumorigenic effects of N-nitrosobutylurea in mice and rats.
    Gan, 1970, Volume: 61, Issue:3

    Topics: Animals; Carcinoma; Female; Leukemia, Experimental; Male; Mammary Neoplasms, Experimental; Mice; Nit

1970
Carcinogenicity of 1-methyl-1-nitrosourea in newborn mice and rats.
    Journal of the National Cancer Institute, 1968, Volume: 41, Issue:3

    Topics: Animals; Animals, Newborn; Carcinogens; Injections, Subcutaneous; Kidney Neoplasms; Leukemia, Experi

1968
[The effect of various doses of nitrosomethyl (ethyl) urea on the development of spontaneous leukosis and tumors in mice].
    Voprosy onkologii, 1969, Volume: 15, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinogens; Leukemia, Experimental; Mammary Neoplasms, Experimental

1969
Uterine, vaginal and mammary tumours induced by nitrosoureas in pregnant rats.
    Nature, 1969, Jun-14, Volume: 222, Issue:5198

    Topics: Animals; Female; Injections, Intraperitoneal; Injections, Intravenous; Mammary Neoplasms, Experiment

1969
Effect of hydroxyurea and related compounds on HMC mammary tumor growth and nucleic acids in Fischer rats.
    Cancer research, 1966, Volume: 26, Issue:11

    Topics: Animals; Antineoplastic Agents; DNA, Neoplasm; Hydroxyurea; Male; Mammary Neoplasms, Experimental; N

1966
Effect of hydroxyurea on growth of a transplantable mouse mammary adenocarcinoma.
    Cancer research, 1966, Volume: 26, Issue:11

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Chorionic Gonadotropin; Female; Hydroxyprogesterones

1966