urea has been researched along with Experimental Leukemia in 27 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Urea was compared to thiourea." | 1.25 | Maturation of membrane function: the permeability of the rat erythroblastic leukemic cell to water and to non-electrolytes. ( Hempling, HG; Wise, WC, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Minn, I | 1 |
| Huss, DJ | 1 |
| Ahn, HH | 1 |
| Chinn, TM | 1 |
| Park, A | 1 |
| Jones, J | 1 |
| Brummet, M | 1 |
| Rowe, SP | 1 |
| Sysa-Shah, P | 1 |
| Du, Y | 1 |
| Levitsky, HI | 1 |
| Pomper, MG | 1 |
| Dawson, MA | 1 |
| Curry, JE | 1 |
| Barber, K | 1 |
| Beer, PA | 1 |
| Graham, B | 1 |
| Lyons, JF | 1 |
| Richardson, CJ | 1 |
| Scott, MA | 1 |
| Smyth, T | 1 |
| Squires, MS | 1 |
| Thompson, NT | 1 |
| Green, AR | 1 |
| Wallis, NG | 1 |
| Leggans, EK | 1 |
| Duncan, KK | 1 |
| Barker, TJ | 1 |
| Schleicher, KD | 1 |
| Boger, DL | 1 |
| STEARNS, B | 1 |
| LOSEE, KA | 1 |
| BERNSTEIN, J | 1 |
| GOLDIN, A | 2 |
| VENDITTI, JM | 1 |
| MEAD, JA | 1 |
| GLYNN, JP | 1 |
| Li, C | 1 |
| Mella, SL | 1 |
| Sartorelli, AC | 1 |
| Zee-Cheng, RK | 1 |
| Cheng, CC | 1 |
| Hempling, HG | 1 |
| Wise, WC | 1 |
| Preisler, HD | 1 |
| Christoff, G | 1 |
| Taylor, E | 1 |
| Raeymaekers, HH | 1 |
| Callens, F | 1 |
| Eisendrath, H | 1 |
| Atassi, G | 1 |
| Fossoul, C | 1 |
| Vandewalle, J | 1 |
| Gielen, M | 1 |
| Willem, R | 1 |
| Mihich, E | 1 |
| Simpson, CL | 1 |
| Loth, L | 1 |
| Mulhern, AI | 1 |
| Hadjiolov, D | 1 |
| Veselý, J | 1 |
| Dvorák, M | 1 |
| Cihák, A | 1 |
| Sorm, F | 1 |
| Ehrhart, H | 1 |
| Schwandt, P | 1 |
| Sugiura, K | 1 |
| Odashima, S | 3 |
| Yokoro, K | 1 |
| Imamura, N | 1 |
| Takizawa, S | 1 |
| Nishihara, H | 1 |
| Nishihara, E | 1 |
| Wang, FC | 1 |
| Ivankovic, S | 1 |
| Preussmann, R | 1 |
| Goncharova, SA | 1 |
| Lipchina, LP | 1 |
| Frankfurt, OS | 1 |
| Kelly, MG | 1 |
| O'Gara, RW | 1 |
| Yancey, ST | 1 |
| Botkin, C | 1 |
| Tsukagoshi, S | 1 |
| Kao, MH | 1 |
| Jobst, K | 1 |
| Marytnova, RP | 1 |
| Ronichevskaia, GM | 1 |
| Sekirov, BA | 1 |
| Emanuel', NM | 1 |
| Vermel', EM | 1 |
| Rapoport, IA | 1 |
| Krugliak, SA | 1 |
| Dronova, LM | 1 |
| Ostrovskaia, LA | 1 |
| Tarnowski, GS | 1 |
| Kreis, W | 1 |
| Schmid, FA | 1 |
| Cappuccino, JG | 1 |
| Burchenal, JH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Clinical Study of PSMA-targeted CAR-T Cells in the Treatment of Castration-resistant Prostate Cancer[NCT05354375] | Phase 1 | 20 participants (Anticipated) | Interventional | 2022-12-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
27 other studies available for urea and Experimental Leukemia
| Article | Year |
|---|---|
Imaging CAR T cell therapy with PSMA-targeted positron emission tomography.
Topics: Animals; Antigens, CD19; Antigens, Surface; Glutamate Carboxypeptidase II; Humans; Immunotherapy, Ad | 2019 |
AT9283, a potent inhibitor of the Aurora kinases and Jak2, has therapeutic potential in myeloproliferative disorders.
Topics: Animals; Antineoplastic Agents; Aurora Kinase B; Aurora Kinases; Benzimidazoles; Cell Cycle; Cell Pr | 2010 |
A remarkable series of vinblastine analogues displaying enhanced activity and an unprecedented tubulin binding steric tolerance: C20' urea derivatives.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Division; Drug Screening Assays, Antitumor; Leukemi | 2013 |
HYDROXYUREA. A NEW TYPE OF POTENTIAL ANTITUMOR AGENT.
Topics: Animals; Antineoplastic Agents; Hydroxyurea; Leukemia; Leukemia L1210; Leukemia, Experimental; Mice; | 1963 |
ANTILEUKEMIC ACTIVITY OF HYDROXYUREA (NSC-32065) AND OTHER UREA DERIVATIVES.
Topics: Antineoplastic Agents; Biological Assay; Hydroxyurea; Leukemia; Leukemia, Experimental; Mice; Resear | 1964 |
Cyclic urea and thiourea derivatives as inducers of murine erythroleukemia differentiation.
Topics: Animals; Cell Differentiation; Cells, Cultured; Chemical Phenomena; Chemistry; In Vitro Techniques; | 1981 |
Antileukemic activity of substituted ureidothiazoles, ureidothiadiazoles, and related compounds.
Topics: Animals; Antineoplastic Agents; Leukemia, Experimental; Mice; Structure-Activity Relationship; Thiad | 1979 |
Maturation of membrane function: the permeability of the rat erythroblastic leukemic cell to water and to non-electrolytes.
Topics: Animals; Benz(a)Anthracenes; Cell Membrane; Cell Membrane Permeability; Cells, Cultured; Computers, | 1975 |
Cryoprotective agents as inducers of erythroleukemic cell differentiation in vitro.
Topics: Acetamides; Animals; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; Heme; Leukemia, Erythrobla | 1976 |
The relationship between serum water proton T1 and protein content in the P388 leukemic mouse and the effect of chemotherapy by cis-diamminedichloroplatinum(II).
Topics: Animals; Blood Proteins; Cisplatin; Creatinine; Kidney; Leukemia P388; Leukemia, Experimental; Magne | 1988 |
Toxic and patologic effects of 4,4'-diacetyl-diphenyl-urea-bis(guanylhydrazone), a new antileukemic agent.
Topics: Alopecia; Animals; Antineoplastic Agents; Chemical and Drug Induced Liver Injury; Dogs; Drug Eruptio | 1969 |
Thymic lymphoma and myeloid leukemia in the rat induced with ethylnitrosourea.
Topics: Animals; Leukemia, Experimental; Leukemia, Myeloid; Lymphoma, Non-Hodgkin; Male; Neoplasms, Experime | 1972 |
Biochemical mechanisms of drug resistance. XII. Uridine kinases from mouse leukemic cells sensitive and resistant to 5-azacytidine.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chloromercuribenzoates; Cytidine; Cytosine Nucl | 1971 |
NAD, ATP and lipid contents in normal and leukemic human leukocytes, before and after cytostatic therapy.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Busulfan; Cholesterol; Cyclophosphamide; Fat | 1972 |
Effect of 1,3-bis(2-chloroethyl)-1-nitrosourea (NSC-409962) and two related compounds on a spectrum of tumors.
Topics: Adenocarcinoma; Animals; Carcinoma, Ehrlich Tumor; Carcinoma, Krebs 2; Fibrosarcoma; Glioma; Hydroxy | 1967 |
Leukemogenesis of N-nitrosobutylurea in the rat. I. Effect of various concentrations in the drinking water to female Donryu rats.
Topics: Animals; Body Weight; Carcinogens; Ear Neoplasms; Esophageal Neoplasms; Intestinal Polyps; Leukemia, | 1970 |
Leukemogenic and mammary tumorigenic effects of N-nitrosobutylurea in mice and rats.
Topics: Animals; Carcinoma; Female; Leukemia, Experimental; Male; Mammary Neoplasms, Experimental; Mice; Nit | 1970 |
Establishment of four lines of transplantable rat leukemia induced by N-nitrosobutylurea in Donryu rats.
Topics: Animals; Carcinogens; Cell Line; Female; Leukemia, Experimental; Neoplasm Transplantation; Nitroso C | 1970 |
[Transplacental formation of malignant tumors after oral administration of ethylurea and nitrite to rats].
Topics: Administration, Oral; Animals; Female; Leukemia, Experimental; Maternal-Fetal Exchange; Neoplasms, E | 1970 |
[Disturbances in the life cycle of leukemic cells by N-nitrosopropylurea].
Topics: Animals; DNA, Neoplasm; Leukemia, Experimental; Mice; Mitosis; Nitroso Compounds; Thymidine; Tritium | 1967 |
Carcinogenicity of 1-methyl-1-nitrosourea in newborn mice and rats.
Topics: Animals; Animals, Newborn; Carcinogens; Injections, Subcutaneous; Kidney Neoplasms; Leukemia, Experi | 1968 |
Effect of 1,3-bis(2-chloroethyl)-1-nitrosourea (NSC-409962) and cyclophosphamide (NSC-26271) on nicotinamide adenine dinucleotide glycohydrolase in normal and leukemic mouse tissues.
Topics: Animals; Brain; Cyclophosphamide; Glycoside Hydrolases; Leukemia, Experimental; Male; Mice; Nitroso | 1968 |
On the DNA and histone content of N-nitrosomethylurea induced rat tumours.
Topics: Adenoma; Aneuploidy; Animals; Brain Neoplasms; Bronchial Neoplasms; Carcinoma; DNA; DNA, Neoplasm; F | 1969 |
Development of leukemia in rats by oral administration of N-nitrosobutylurea in the drinking water.
Topics: Adrenal Glands; Animals; Female; Kidney; Leukemia, Experimental; Liver; Lymphatic Metastasis; Nitros | 1969 |
[The effect of various doses of nitrosomethyl (ethyl) urea on the development of spontaneous leukosis and tumors in mice].
Topics: Animals; Antineoplastic Agents; Carcinogens; Leukemia, Experimental; Mammary Neoplasms, Experimental | 1969 |
[The antitumorous properties of powerful chemical mutagenes (derivatives of nitrosourea)].
Topics: Animals; Antineoplastic Agents; Carcinoma, Ehrlich Tumor; Leukemia, Experimental; Mice; Mutagens; Ni | 1965 |
Effect of hydroxylamine (NSC-26250) and related compounds on growth of transplanted animal tumors.
Topics: Animals; Female; Hydroxylamines; Leukemia, Experimental; Male; Mice; Neoplasms, Experimental; Rats; | 1966 |