Page last updated: 2024-10-21

urea and Epilepsy, Complex Partial

urea has been researched along with Epilepsy, Complex Partial in 1 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Epilepsy, Complex Partial: A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8)

Research Excerpts

ExcerptRelevanceReference
"Valproic acid (VPA) is a major antiepileptic drug (AED); however, its use is limited by two life-threatening side effects: teratogenicity and hepatotoxicity."1.34Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid. ( Bialer, M; Finnell, RH; Shimshoni, JA; Wlodarczyk, B; Yagen, B, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shimshoni, JA1
Bialer, M1
Wlodarczyk, B1
Finnell, RH1
Yagen, B1

Other Studies

1 other study available for urea and Epilepsy, Complex Partial

ArticleYear
Potent anticonvulsant urea derivatives of constitutional isomers of valproic acid.
    Journal of medicinal chemistry, 2007, Dec-13, Volume: 50, Issue:25

    Topics: Abnormalities, Drug-Induced; Animals; Anticonvulsants; Epilepsy, Complex Partial; Mice; Rats; Stereo

2007