urea has been researched along with Edema in 102 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Edema: Abnormal fluid accumulation in TISSUES or body cavities. Most cases of edema are present under the SKIN in SUBCUTANEOUS TISSUE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacodynamics of torasemide (1-isopropyl-3- ([4-(3-methyl-phenylamino)pyridine]-3-sulfonyl)urea), a new potent loop diuretic, were compared to those of furosemide in a double-blind controlled study in 18 patients with oedema of various origin." | 9.06 | Comparative pharmacodynamics of torasemide and furosemide in patients with oedema. ( Broekhuysen, J; Deger, F; Douchamps, J; Ducarne, H; Herchuelz, A, 1988) |
| "We have studied the efficacy of urea in the treatment of hyponatremia and hydrosaline retention in cirrhotic patients with ascites resistant to diuretics." | 7.67 | Treatment of hyponatremic cirrhosis with ascites resistant to diuretics by urea. ( Cauchie, P; Decaux, G; Delwiche, F; Flamion, B; Mols, P, 1986) |
| " Furthermore, A-425619 maintained efficacy in the postoperative pain model after twice daily dosing p." | 5.33 | A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats. ( El Kouhen, R; Faltynek, CR; Gauvin, DM; Gomtsyan, A; Honore, P; Jarvis, MF; Lee, CH; Marsh, K; Mikusa, J; Sullivan, JP; Wismer, CT; Zhong, C; Zhu, CZ, 2005) |
| " Participants were receiving 40 mg pimavanserin daily in addition to concurrent antipsychotics and Parkinson disease medications." | 5.20 | Impact of Current Antipsychotic Medications on Comparative Mortality and Adverse Events in People With Parkinson Disease Psychosis. ( Ballard, C; Burn, DJ; Coate, B; Corbett, A; Isaacson, S; Mills, R; Pahwa, R; Rascol, O; Williams, H, 2015) |
| "The pharmacodynamics of torasemide (1-isopropyl-3- ([4-(3-methyl-phenylamino)pyridine]-3-sulfonyl)urea), a new potent loop diuretic, were compared to those of furosemide in a double-blind controlled study in 18 patients with oedema of various origin." | 5.06 | Comparative pharmacodynamics of torasemide and furosemide in patients with oedema. ( Broekhuysen, J; Deger, F; Douchamps, J; Ducarne, H; Herchuelz, A, 1988) |
| "The pharmacodynamic effects of torasemide, a new potent loop diuretic, were compared with those of furosemide in a double blind controlled study in 18 hypertensive patients with oedema of various origins." | 5.06 | Torasemide, a new potent diuretic. Double-blind comparison with furosemide. ( Broekhuysen, J; Deger, F; Douchamps, J; Ducarne, H; Herchuelz, A, 1986) |
| " We report the results of qualitative studies to develop new PRO measures for use in clinical trials of omecamtiv mecarbil (a selective, small molecule activator of cardiac myosin) for patients with heart failure (HF), as well as the lessons learned from the development process." | 3.83 | Incorporating development of a patient-reported outcome instrument in a clinical drug development program: examples from a heart failure program. ( Anatchkova, M; Chau, D; Malik, FI; Oko-Osi, H; Patrick, DL; Spertus, J; Teerlink, JR; von Maltzahn, R; Wiklund, I, 2016) |
| " PAF-induced hemoconcentration and arachidonic acid- and TPA-induced ear edema in mice were used to determine in vivo activities." | 3.70 | (+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist. ( Cai, X; Eckman, J; Hussoin, MS; Hwang, SB; Ip, SH; Killian, DB; Libertine-Garahan, L; Qian, C; Scannell, RT; Shen, TY; Yaeger, D; Yeh, CG, 1998) |
| "The concentrations of urea, creatinine, and uric acid were measured in edema fluid and plasma during hemodialysis and 18 h after hemodialysis." | 3.68 | Evaluation of hemodialysis efficiency by an edema fluid model. ( Fujita, Y; Izumi, M; Kajimoto, Y; Nakahama, H; Ochi, S; Shirai, D; Tanaka, Y; Wada, A; Yano, F, 1992) |
| "A number of arylbiurets were prepared and evaluated as antiinflammatory and analgesic agents by using the carrageenan paw edema and acetic acid stretching tests." | 3.68 | Syntheses, antiinflammatory, and analgesic activities of arylbiurets. ( Fujimura, H; Honna, T; Kajitani, M; Miyake, H; Ogawa, K; Tanaka, M; Yabuuchi, T; Yamada, S; Yamazaki, T, 1990) |
| "We have studied the efficacy of urea in the treatment of hyponatremia and hydrosaline retention in cirrhotic patients with ascites resistant to diuretics." | 3.67 | Treatment of hyponatremic cirrhosis with ascites resistant to diuretics by urea. ( Cauchie, P; Decaux, G; Delwiche, F; Flamion, B; Mols, P, 1986) |
| "Patients with chronic renal failure and on chronic intermittent hemodialysis have several metabolic risks such as retention of urea and other products of nitrogen metabolism, catabolism, acidosis, edema, dehydration, hyper- and hypotension, hyperkalemia, renal osteopathy, and renal anemia." | 3.65 | [Dangers of a wrong diet in patients with renal insufficiency in the predialytic state or during chronic hemodialysis]. ( Hecking, E; Mader, HJ; Zobel, R, 1977) |
| " One became oedema-free with frusemide 240 mg daily, three became oedema-free with frusemide 500 mg daily, and two required a combination of high-dose frusemide and spironolactone." | 3.65 | Salt-poor human albumin in management of nephrotic syndrome. ( Cash, JD; Davison, AM; Lambie, AT; Verth, AH, 1974) |
| "Xipamide is a diuretic derived from salicylic acid and has a structural resemblance to chlorthalidone." | 2.37 | Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. ( Brogden, RN; Prichard, BN, 1985) |
| " However, their long-term use has been associated with considerable morbidity, limiting their application." | 1.35 | Effect of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles on chronic inflammatory pain model in rats. ( Beck, P; Bonacorso, HG; Duarte, MM; Ferreira, J; Machado, P; Martins, MA; Mello, CF; Rubin, MA; Sant'Anna, Gda S; Sauzem, PD; Zanatta, N, 2009) |
| " A number of compounds have been identified to be orally bioavailable and efficacious in the mouse edema model." | 1.35 | Identification of aminopyrazolopyridine ureas as potent VEGFR/PDGFR multitargeted kinase inhibitors. ( Albert, DH; Bouska, JJ; Dai, Y; Davidsen, SK; Doktor, SZ; Glaser, KB; Hartandi, K; Marcotte, PA; Michaelides, MR; Olson, AM; Osterling, DJ; Pease, LJ; Reuter, DR; Soni, NB; Stewart, KD, 2008) |
| " Furthermore, A-425619 maintained efficacy in the postoperative pain model after twice daily dosing p." | 1.33 | A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats. ( El Kouhen, R; Faltynek, CR; Gauvin, DM; Gomtsyan, A; Honore, P; Jarvis, MF; Lee, CH; Marsh, K; Mikusa, J; Sullivan, JP; Wismer, CT; Zhong, C; Zhu, CZ, 2005) |
| "Idiopathic oedema has a strong genetic basis, and correction of major and minor risk factors for this condition leads to substantial amelioration of symptoms in most cases." | 1.29 | The role of diuretics in the aetiology of idiopathic oedema. ( Czapla, K; Duncan, A; Dunnigan, MG; Henderson, JB; Pelosi, AJ, 1995) |
| "Urea has recently been used as an alternative." | 1.27 | Auditory dehydration testing: glycerol versus urea. ( Arenberg, IK; Balkany, TJ; Van de Water, SM, 1986) |
| "Total starvation is effective for acute weight reduction in obesity." | 1.26 | [Complications in null-diet]. ( Mordasini, R; Oster, P; Raetzer, H; Schellenberg, B; Schlierf, G, 1977) |
| "Forty patients with generalized cancer complicated by water and electrolyte retention were treated with "medium" and "large" doses of furosemide and bumetanide with 35% and 40% objective positive response, respectively." | 1.26 | Diuretics in malignant effusions and edemas of generalized cancer. ( Athanasiou, A; Dadiotis, L; Razis, DV, 1976) |
| " Taking the stated dosage instructions and contra-indications into consideration, beta-aescin can thus be administered without hesitation." | 1.25 | [The prevention and treatment of post-operative and post-traumatic oedema. Chemical laboratory tests on the renal tolerance of beta-aescin (reparil) (author's transl)]. ( Feldmeier, C; Wilhelm, K, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 77 (75.49) | 18.7374 |
| 1990's | 5 (4.90) | 18.2507 |
| 2000's | 12 (11.76) | 29.6817 |
| 2010's | 7 (6.86) | 24.3611 |
| 2020's | 1 (0.98) | 2.80 |
| Authors | Studies |
|---|---|
| Abedi, B | 1 |
| Tayebi Khosroshahi, H | 1 |
| Carvalho, LH | 1 |
| Teixeira, LF | 1 |
| Zaqueo, KD | 1 |
| Bastos, JF | 1 |
| Nery, NM | 1 |
| Setúbal, SS | 1 |
| Pontes, AS | 1 |
| Butzke, D | 1 |
| Cavalcante, W | 1 |
| Gallacci, M | 1 |
| Fernandes, CFC | 1 |
| Stabeli, RG | 1 |
| Soares, AM | 1 |
| Zuliani, JP | 1 |
| Salah, K | 1 |
| Stienen, S | 1 |
| Moons, AHM | 1 |
| Bakx, ALM | 1 |
| van Pol, PE | 1 |
| Kortz, RAM | 1 |
| Ferreira, JP | 1 |
| Marques, I | 1 |
| Schroeder-Tanka, JM | 1 |
| Keijer, JT | 1 |
| Bayes-Genis, A | 1 |
| Pinto, YM | 1 |
| Tijssen, JG | 1 |
| Kok, WE | 1 |
| Haseena banu, B | 1 |
| Prasad, KV | 1 |
| Bharathi, K | 1 |
| Ballard, C | 1 |
| Isaacson, S | 1 |
| Mills, R | 1 |
| Williams, H | 1 |
| Corbett, A | 1 |
| Coate, B | 1 |
| Pahwa, R | 1 |
| Rascol, O | 1 |
| Burn, DJ | 1 |
| Wiklund, I | 1 |
| Anatchkova, M | 1 |
| Oko-Osi, H | 1 |
| von Maltzahn, R | 1 |
| Chau, D | 1 |
| Malik, FI | 1 |
| Patrick, DL | 1 |
| Spertus, J | 1 |
| Teerlink, JR | 1 |
| Frey, RR | 3 |
| Curtin, ML | 3 |
| Albert, DH | 4 |
| Glaser, KB | 4 |
| Pease, LJ | 4 |
| Soni, NB | 3 |
| Bouska, JJ | 4 |
| Reuter, D | 1 |
| Stewart, KD | 4 |
| Marcotte, P | 1 |
| Bukofzer, G | 1 |
| Li, J | 2 |
| Davidsen, SK | 4 |
| Michaelides, MR | 4 |
| Zhu, BL | 1 |
| Zhao, R | 1 |
| Li, RB | 1 |
| Wu, X | 1 |
| Guan, DW | 1 |
| Zhang, GH | 1 |
| Sauzem, PD | 1 |
| Sant'Anna, Gda S | 1 |
| Machado, P | 1 |
| Duarte, MM | 1 |
| Ferreira, J | 1 |
| Mello, CF | 1 |
| Beck, P | 1 |
| Bonacorso, HG | 1 |
| Zanatta, N | 1 |
| Martins, MA | 1 |
| Rubin, MA | 1 |
| Chen, L | 1 |
| Dang, Q | 1 |
| Liu, C | 1 |
| Chen, J | 1 |
| Song, L | 1 |
| Chen, X | 1 |
| de Oliveira Lopes, R | 1 |
| Romeiro, NC | 1 |
| de Lima, CK | 1 |
| Louback da Silva, L | 1 |
| de Miranda, AL | 1 |
| Nascimento, PG | 1 |
| Cunha, FQ | 1 |
| Barreiro, EJ | 1 |
| Lima, LM | 1 |
| ELLIOT, A | 1 |
| CHOJNOWSKI, JR | 1 |
| PAPP, C | 1 |
| SMITH, KS | 1 |
| GAZZANO, AM | 1 |
| MOSELLI, M | 1 |
| MATTER, P | 1 |
| McANINCH, J | 1 |
| McCULLOUGH, JA | 1 |
| JADRNY, J | 1 |
| REITH, JF | 1 |
| KOGA, T | 1 |
| SAKAMOTO, K | 1 |
| DAVID, M | 1 |
| DELIGNE, P | 1 |
| SALISBURY, PF | 1 |
| POMERANZ, AA | 1 |
| THOMSON, WB | 1 |
| BUCHANAN, AA | 1 |
| DOAK, PB | 1 |
| PEART, WS | 1 |
| LEN, A | 1 |
| OBRADOR, S | 1 |
| QUEIMADELOS, V | 1 |
| KROGSGAARD, AR | 1 |
| KRAGH, PL | 1 |
| SALVATORES, U | 1 |
| BELLI, I | 1 |
| BROCK, M | 1 |
| STRUCK, G | 1 |
| UMBACH, W | 1 |
| LAZORTHES, G | 1 |
| CAMPAN, L | 1 |
| GOMBOS, EA | 1 |
| LEE, TH | 1 |
| HARTON, MR | 1 |
| CUMMINGS, JW | 1 |
| BLAGOJEVIC, M | 1 |
| MILENKOVIC, P | 1 |
| SEMB, C | 1 |
| WEST, JB | 1 |
| DOLLERY, CT | 1 |
| HEARD, BE | 1 |
| MINOWA, T | 1 |
| PARSONS, TC | 1 |
| BREMNER, JD | 1 |
| KRISCH, W | 1 |
| Vodegel, RM | 1 |
| Kardaun, SH | 1 |
| Honore, P | 1 |
| Wismer, CT | 1 |
| Mikusa, J | 1 |
| Zhu, CZ | 1 |
| Zhong, C | 1 |
| Gauvin, DM | 1 |
| Gomtsyan, A | 1 |
| El Kouhen, R | 1 |
| Lee, CH | 1 |
| Marsh, K | 1 |
| Sullivan, JP | 1 |
| Faltynek, CR | 1 |
| Jarvis, MF | 1 |
| Alhan, E | 1 |
| Kalyoncu, NI | 1 |
| Ercin, C | 1 |
| Kural, BV | 1 |
| Dai, Y | 2 |
| Guo, Y | 1 |
| Ji, Z | 1 |
| Ahmed, AA | 2 |
| Arnold, L | 1 |
| Arries, SS | 1 |
| Barlozzari, T | 1 |
| Bauch, JL | 1 |
| Bousquet, PF | 2 |
| Cunha, GA | 2 |
| Guo, J | 1 |
| Marcotte, PA | 3 |
| Marsh, KC | 1 |
| Moskey, MD | 2 |
| Stoll, VS | 1 |
| Tapang, P | 1 |
| Wishart, N | 1 |
| Heyman, HR | 1 |
| Yates, M | 1 |
| Black-Schaefer, CL | 1 |
| Dandliker, PJ | 1 |
| Rafferty, P | 1 |
| Liamis, G | 1 |
| Christidis, D | 1 |
| Alexandridis, G | 1 |
| Bairaktari, E | 1 |
| Madias, NE | 1 |
| Elisaf, M | 1 |
| Hartandi, K | 1 |
| Reuter, DR | 1 |
| Olson, AM | 1 |
| Osterling, DJ | 1 |
| Doktor, SZ | 1 |
| Angelopoulos, B | 1 |
| Vlassopoulos, C | 1 |
| Kalos, A | 1 |
| Vaamonde, CA | 1 |
| Vaamonde, LS | 1 |
| Morosi, HJ | 1 |
| Klingler, EL | 1 |
| Papper, S | 1 |
| Coyne, WE | 1 |
| Cusic, JW | 1 |
| Velický, J | 1 |
| Tzamaloukas, AH | 1 |
| Pelosi, AJ | 1 |
| Czapla, K | 1 |
| Duncan, A | 1 |
| Henderson, JB | 1 |
| Dunnigan, MG | 1 |
| Cai, X | 2 |
| Scannell, RT | 2 |
| Yaeger, D | 1 |
| Hussoin, MS | 1 |
| Killian, DB | 1 |
| Qian, C | 2 |
| Eckman, J | 1 |
| Hwang, SB | 2 |
| Libertine-Garahan, L | 2 |
| Yeh, CG | 2 |
| Ip, SH | 1 |
| Shen, TY | 1 |
| Hu, MC | 1 |
| Bankir, L | 1 |
| Michelet, S | 1 |
| Rousselet, G | 1 |
| Trinh-Trang-Tan, MM | 1 |
| Eckman, JB | 1 |
| Srivastava, RN | 1 |
| Mayekar, G | 1 |
| Anand, R | 1 |
| Choudhry, VP | 1 |
| Ghai, OP | 1 |
| Tandon, HD | 1 |
| Barbosa-Saldivar, JL | 1 |
| Van Itallie, TB | 1 |
| Hecking, E | 1 |
| Zobel, R | 1 |
| Mader, HJ | 1 |
| Smitskampen, H | 1 |
| Wolthuis, FH | 1 |
| Wilhelm, K | 1 |
| Feldmeier, C | 1 |
| Oster, P | 1 |
| Mordasini, R | 1 |
| Raetzer, H | 1 |
| Schellenberg, B | 1 |
| Schlierf, G | 1 |
| Kishore, V | 1 |
| Kumar, S | 1 |
| Parmar, SS | 1 |
| Stenberg, VI | 1 |
| Razis, DV | 1 |
| Athanasiou, A | 1 |
| Dadiotis, L | 1 |
| Stehle, R | 1 |
| Feyen, H | 1 |
| Hiemeyer, V | 1 |
| Shirai, D | 1 |
| Kajimoto, Y | 1 |
| Ochi, S | 1 |
| Tanaka, Y | 1 |
| Wada, A | 1 |
| Yano, F | 1 |
| Izumi, M | 1 |
| Fujita, Y | 1 |
| Nakahama, H | 1 |
| Kajitani, M | 1 |
| Yamazaki, T | 1 |
| Yamada, S | 1 |
| Tanaka, M | 1 |
| Ogawa, K | 1 |
| Honna, T | 1 |
| Miyake, H | 1 |
| Yabuuchi, T | 1 |
| Fujimura, H | 1 |
| Herchuelz, A | 2 |
| Deger, F | 2 |
| Douchamps, J | 2 |
| Ducarne, H | 2 |
| Broekhuysen, J | 2 |
| Van de Water, SM | 1 |
| Arenberg, IK | 1 |
| Balkany, TJ | 1 |
| Decaux, G | 2 |
| Mols, P | 2 |
| Cauchie, P | 1 |
| Flamion, B | 1 |
| Delwiche, F | 2 |
| Prichard, BN | 1 |
| Brogden, RN | 1 |
| Cauchi, P | 1 |
| Yazawa, Y | 1 |
| Shea, JJ | 1 |
| Holloway, R | 1 |
| Vaughan, ED | 1 |
| Gillenwater, JY | 1 |
| Cormier, JM | 1 |
| von Kreybig, T | 1 |
| Preussmann, R | 1 |
| von Kreybig, I | 1 |
| Kennedy, AC | 1 |
| Burton, JA | 1 |
| Allison, ME | 1 |
| Forbes, MJ | 1 |
| Sinclair, L | 1 |
| Macfarlane, JP | 2 |
| Kennedy, RD | 2 |
| Caraway, WT | 1 |
| Davies, DL | 1 |
| Lant, AF | 1 |
| Millard, NR | 1 |
| Smith, AJ | 1 |
| Ward, JW | 1 |
| Wilson, GM | 1 |
| Leary, WP | 1 |
| Asmal, AC | 1 |
| Seedat, YK | 1 |
| Samuel, P | 1 |
| Robertson, EG | 1 |
| Cheyne, GA | 1 |
| Davies, DP | 1 |
| Saunders, R | 1 |
| Gray, OP | 1 |
| Friedmann, I | 1 |
| Bauer, F | 1 |
| Lowenthal, DT | 1 |
| Shear, L | 1 |
| Zòltowska, A | 1 |
| Wrzolkowa, T | 1 |
| Wick, H | 1 |
| Bachmann, C | 1 |
| Baumgartner, R | 1 |
| Brechbühler, T | 1 |
| Colombo, JP | 1 |
| Wiesmann, U | 1 |
| Mihatsch, MJ | 1 |
| Ohnacker, H | 1 |
| Davison, AM | 1 |
| Lambie, AT | 1 |
| Verth, AH | 1 |
| Cash, JD | 1 |
| van Wieringen, PM | 1 |
| Monnens, LA | 1 |
| Schretlen, ED | 1 |
| Swales, JD | 1 |
| Tange, JD | 1 |
| Evans, DJ | 1 |
| Harman, JW | 1 |
| Crank, G | 1 |
| Foulis, MJ | 1 |
| McDonald, R | 1 |
| Wiggelinkhuizen, J | 1 |
| Kaschula, RO | 1 |
| Nizet, A | 1 |
| Cuypers, Y | 1 |
| Deetjen, P | 1 |
| Kramer, K | 1 |
| Bietti, GB | 1 |
| Pecori-Giraldi, J | 1 |
| Stephens, AD | 1 |
| Watts, RW | 1 |
| Roesner, J | 1 |
| Rorive, G | 1 |
| Hagemeijer, F | 1 |
| Luyckx, A | 1 |
| Van Cauwenberge, H | 1 |
| Glen, AI | 1 |
| Halliburton, IM | 1 |
| MacDonald, AC | 1 |
| Furukawa, T | 1 |
| Urakabe, S | 1 |
| Abe, H | 1 |
| Jaffe, NS | 1 |
| Light, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-Center, Open-Label Extension Study to Examine the Safety and Tolerability of ACP-103 in the Treatment of Psychosis in Parkinson's Disease[NCT00550238] | Phase 3 | 459 participants (Actual) | Interventional | 2007-07-31 | Completed | ||
| A Multinational Prospective Study on the Duration of Steroid Therapy in Steroid Sensitive Nephrotic Syndrome[NCT03878914] | Phase 4 | 34 participants (Actual) | Interventional | 2019-08-06 | Terminated (stopped due to The study was terminated at all but one site because of the pandemic) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number (%) of patients with drug-related treatment-emergent AEs (i.e. AEs reported by the Investigator as possibly, probably, or highly probably related to study drug) (NCT00550238)
Timeframe: From first to last study drug dose plus 30 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Pimavanserin | 180 |
2 reviews available for urea and Edema
| Article | Year |
|---|---|
Semistarvation: an overview of an old problem.
Topics: Adolescent; Adult; Amenorrhea; Animals; Anorexia Nervosa; Child; Edema; Female; Growth Hormone; Huma | 1979 |
Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy.
Topics: Animals; Body Weight; Diuretics; Edema; Electrolytes; Half-Life; Humans; Hypertension; Intestinal Ab | 1985 |
7 trials available for urea and Edema
| Article | Year |
|---|---|
Impact of Current Antipsychotic Medications on Comparative Mortality and Adverse Events in People With Parkinson Disease Psychosis.
Topics: Accidental Falls; Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Antipsychotic Agents; Drug T | 2015 |
Comparative pharmacodynamics of torasemide and furosemide in patients with oedema.
Topics: Aged; Aged, 80 and over; Blood Pressure; Blood Urea Nitrogen; Body Weight; Clinical Trials as Topic; | 1988 |
Torasemide, a new potent diuretic. Double-blind comparison with furosemide.
Topics: Aged; Aged, 80 and over; Body Weight; Clinical Trials as Topic; Creatinine; Diuretics; Double-Blind | 1986 |
Renal action, therapeutic use, and pharmacokinetics of the diuretic bumetanide.
Topics: Autoanalysis; Benzoates; Bicarbonates; Butylamines; Calcium; Carbon Radioisotopes; Chlorides; Chroma | 1974 |
The effects of amiloride during diuretic therapy in elderly subjects.
Topics: Administration, Oral; Aged; Amiloride; Calcium; Clinical Trials as Topic; Diuretics; Drug Combinatio | 1972 |
Initial responses of oedematous patients to furosemide and S1520.
Topics: Ankle; Bicarbonates; Blood Glucose; Blood Pressure; Calcium; Chemical Phenomena; Chemistry; Chloride | 1974 |
The treatment of cystinuria with N-acetyl-D-penicillamine, a comparison with the results of D-penicillamine treatment.
Topics: Acylation; Adolescent; Adult; Child; Cysteine; Cystinuria; Desensitization, Immunologic; Drug Hypers | 1971 |
93 other studies available for urea and Edema
| Article | Year |
|---|---|
Excretion of Nitrogenous Waste Products from the Intestinal Fluid Simulator Using Super Absorbent Polymer: A New Generation Dialysis.
Topics: Creatinine; Edema; Electrolytes; Humans; Polymers; Renal Dialysis; Urea; Uric Acid; Waste Products | 2023 |
Local and systemic effects caused by Crotalus durissus terrificus, Crotalus durissus collilineatus, and Crotalus durissus cascavella snake venoms in swiss mice.
Topics: Alkaline Phosphatase; Animals; Creatine Kinase; Creatinine; Crotalid Venoms; Crotalus; Edema; Electr | 2019 |
External Validation of the ELAN-HF Score, Predicting 6-Month All-Cause Mortality in Patients Hospitalized for Acute Decompensated Heart Failure.
Topics: Acute Disease; Age Factors; Aged; Blood Pressure; Cause of Death; Edema; Female; Heart Failure; Hosp | 2019 |
Synthesis and biological evaluation of N-dehydrodipeptidyl-N,N'-dicyclohexylurea analogs.
Topics: Acetic Acid; Analgesics; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; An | 2014 |
Incorporating development of a patient-reported outcome instrument in a clinical drug development program: examples from a heart failure program.
Topics: Aged; Aged, 80 and over; Cardiac Myosins; Cardiovascular Agents; Clinical Trials as Topic; Dizziness | 2016 |
7-Aminopyrazolo[1,5-a]pyrimidines as potent multitargeted receptor tyrosine kinase inhibitors.
Topics: Animals; Edema; Female; Male; Mice; Models, Molecular; Molecular Structure; Phenylurea Compounds; Pr | 2008 |
Fatal acute compartment syndrome in patients after surgical treatment: 2 case reports.
Topics: Adult; C-Reactive Protein; Casts, Surgical; Child; Compartment Syndromes; Creatinine; Edema; Female; | 2009 |
Effect of 5-trifluoromethyl-4,5-dihydro-1H-pyrazoles on chronic inflammatory pain model in rats.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Body Weight; Chronic Disease | 2009 |
Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Carriers; Edema; Ibup | 2012 |
Docking, synthesis and pharmacological activity of novel urea-derivatives designed as p38 MAPK inhibitors.
Topics: Animals; Carrageenan; Dose-Response Relationship, Drug; Drug Design; Edema; Female; Male; Mice; Mole | 2012 |
Hyperchloremia, azotemia and pulmonary edema of cerebral origin.
Topics: Azotemia; Blood; Chlorides; Edema; Humans; Lung Diseases; Multiple Sclerosis; Nitrogen; Pulmonary Ed | 1955 |
[Combined urea, protein, and plant therapy of ascites and edema in chronic circulatory failure complicated by sclerosis of the liver].
Topics: Ascites; Diuretics; Edema; Heart Failure; Liver Diseases; Proteins; Sclerosis; Urea | 1955 |
Urea, the forgotten diuretic.
Topics: Diuretics; Edema; Humans; Memory Disorders; Urea | 1957 |
[Hypertonic urea for the control of acute traumatic cerebral edema].
Topics: Brain; Brain Edema; Brain Injuries; Edema; Humans; Urea | 1961 |
Evaluation of oliguria and edema in acute experimental burns with the use of urea.
Topics: Anuria; Burns; Burns, Chemical; Edema; Humans; Oliguria; Urea | 1962 |
[A review of therapeutic measures used in cerebral edema with special reference to the use of hypertonic solutions of urea].
Topics: Brain Diseases; Brain Edema; Edema; Humans; Hypertonic Solutions; Urea | 1962 |
[The search for the chick edema factor].
Topics: Animals; Bird Diseases; Chickens; Edema; Fats; Poultry Diseases; Urea; Viper Venoms | 1963 |
[EXPERIMENTAL STUDIES ON PREVENTION AND TREATMENT OF THE CRITICAL COMPLICATIONS CAUSED BY THE ACUTE BRAIN COMPRESSION].
Topics: Animals; Brain; Brain Diseases; Cerebral Angiography; Cerebral Arteries; Dogs; Edema; Electrocardiog | 1963 |
IDENTIFICATION OF THE PRESSOR SUBSTANCE PRODUCED IN EXPERIMENTAL NEPHRITIS AND PREVENTION OF THE HYPERTENSION BY A SURGICAL PROCEDURE.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dogs; Edema; Hematuria; Hypertension; Liver Circul | 1963 |
[OSMOTIC TREATMENT OF CEREBRAL EDEMA WITH AN INJECTABLE HYPERTONIC UREA-MANNITOL SOLUTION].
Topics: Brain Diseases; Brain Edema; Edema; Humans; Hypertonic Solutions; Intracranial Pressure; Mannitol; N | 1963 |
UREMIC TOXICITY CORRELATED WITH UNIDENTIFIED ANIONS.
Topics: Anions; Blood Chemical Analysis; Creatine; Creatinine; Edema; Glomerulonephritis; Ileostomy; Kidney; | 1963 |
PERITONEAL DIALYSIS.
Topics: Acute Kidney Injury; Bicarbonates; Blood Chemical Analysis; Dialysis; Edema; Geriatrics; Kidney Dise | 1964 |
[WHAT TO DO WHEN CONFRONTED WITH A CRANIAL INJURY].
Topics: Brain Injuries; Cerebral Hemorrhage; Craniocerebral Trauma; Edema; Humans; Hypertonic Solutions; Inf | 1963 |
A RADIOLOGICAL METHOD OF FOLLOWING CHANGES AND DISPLACEMENTS OF THE BRAIN AFTER SURGERY.
Topics: Brain; Brain Diseases; Brain Neoplasms; Edema; Humans; Neurosurgery; Postoperative Complications; Ra | 1964 |
[TRIAMTERENE, A POTASSIUM-RETAINING DIURETIC. CLINICAL INVESTIGATIONS IN PATIENTS WITH EDEMA].
Topics: Benzothiadiazines; Blood Chemical Analysis; Chlorides; Creatine; Creatinine; Diuretics; Edema; Potas | 1964 |
[ON THE VALUE OF THE USE OF UREA IN PNEUMOENCEPHALOGRAPHY].
Topics: Adolescent; Atrophy; Brain Diseases; Brain Neoplasms; Cerebral Ventriculography; Child; Edema; Human | 1964 |
[ON THE USE OF UREA IN THE TREATMENT OF CEREBRAL EDEMA].
Topics: Brain Diseases; Brain Edema; Edema; Urea | 1964 |
[COMPARATIVE ELECTRONOPTIC STUDIES ON THE HUMAN CEREBRAL CORTEX BEFORE AND AFTER EDEMA THERAPY].
Topics: Brain Edema; Brain Neoplasms; Cerebral Cortex; Edema; Electrons; Humans; Intracranial Pressure; Micr | 1964 |
[CEREBRAL EDEMA. PRESENT STATUS OF THE QUESTION].
Topics: Adrenocorticotropic Hormone; Brain Diseases; Brain Edema; Cerebral Angiography; Cortisone; Diuretics | 1963 |
ONE YEAR'S EXPERIENCE WITH AN INTERMITTENT DIALYSIS PROGRAM.
Topics: Blood Chemical Analysis; Blood Urea Nitrogen; Creatine; Creatinine; Dialysis; Diet; Diet Therapy; Ed | 1964 |
[FAVORABLE EFFECT OF INTRAVENOUS UREA IN BILATERAL ACUTE EDEMATOUS OPTIC NEURITIS].
Topics: Adolescent; Drug Therapy; Edema; Humans; Hypertonic Solutions; Injections, Intravenous; Optic Neurit | 1964 |
CONSERVATIVE KIDNEY SURGERY; PARTIAL KIDNEY RESECTION.
Topics: Edema; Geriatrics; Humans; Hydronephrosis; Hypothermia; Hypothermia, Induced; Kidney; Kidney Calculi | 1965 |
INCREASED PULMONARY VASCULAR RESISTANCE IN THE DEPENDENT ZONE OF THE ISOLATED DOG LUNG CAUSED BY PERIVASCULAR EDEMA.
Topics: Chemotherapy, Cancer, Regional Perfusion; Dogs; Edema; Hypertension; Hypertension, Pulmonary; Lung; | 1965 |
[Cerebral swelling and the blood-brain barrier, with special reference to the correlation of drugs lowering brain pressure and urea].
Topics: Blood-Brain Barrier; Brain; Brain Diseases; Brain Edema; Edema; Edetic Acid; Humans; Urea | 1962 |
The use of urea in the management of post ictal confusion associated with cerebral and generalized edema.
Topics: Brain; Brain Diseases; Confusion; Edema; Edetic Acid; Electroconvulsive Therapy; Mental Disorders; S | 1962 |
[Edema caused by constant use of sleeping medicines urea derivatives and its treatment].
Topics: Edema; Hypnotics and Sedatives; Sleep; Urea | 1951 |
[Periorbital swelling caused by carbasalate calcium].
Topics: Aspirin; Diagnosis, Differential; Edema; Eyelid Diseases; Eyelids; Humans; Male; Middle Aged; Platel | 2004 |
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats.
Topics: Acute Disease; Analgesics; Animals; Capsaicin; Carrageenan; Chronic Disease; Dose-Response Relations | 2005 |
Effects of the celecoxib on the acute necrotizing pancreatitis in rats.
Topics: Animals; Celecoxib; Ceruletide; Cyclooxygenase Inhibitors; Disease Models, Animal; Edema; Glycodeoxy | 2004 |
Thienopyrimidine ureas as novel and potent multitargeted receptor tyrosine kinase inhibitors.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents; Edema; Estradiol; Female; Humans; Mice; Mice | 2005 |
Thienopyridine urea inhibitors of KDR kinase.
Topics: Animals; Disease Models, Animal; Edema; Estradiol; Female; Mice; Models, Molecular; Pyridines; Struc | 2007 |
Uric acid homeostasis in the evaluation of diuretic-induced hyponatremia.
Topics: Aged; Creatinine; Diagnosis, Differential; Diuretics; Edema; Female; Humans; Hyponatremia; Hypovolem | 2007 |
Identification of aminopyrazolopyridine ureas as potent VEGFR/PDGFR multitargeted kinase inhibitors.
Topics: Administration, Oral; Aminopyridines; Animals; Biological Availability; Edema; Female; Inhibitory Co | 2008 |
Experimental investigation and observations on the diuretic action of quinethazone.
Topics: Acetazolamide; Adult; Chlorides; Chlorothiazide; Creatine; Diuresis; Drug Synergism; Edema; Female; | 1966 |
Renal concentrating ability in cirrhosis. I. Changes associated with the clinical status and course of the disease.
Topics: Absorption; Adult; Ascites; Bilirubin; Creatine; Edema; Female; Humans; Kidney Diseases; Kidney Func | 1967 |
Antiinflammatory dialkylaminoalkylureas.
Topics: Animals; Biological Assay; Candida; Chemistry, Organic; Edema; Granuloma; Male; Organic Chemistry Ph | 1967 |
[The treatment of retinal edema with urea].
Topics: Edema; Humans; Retina; Urea | 1967 |
Effect of edema on urea kinetic studies in peritoneal dialysis patients.
Topics: Edema; Humans; Male; Peritoneal Dialysis, Continuous Ambulatory; Urea | 1994 |
The role of diuretics in the aetiology of idiopathic oedema.
Topics: Adult; Aged; Cathartics; Diuretics; Edema; Female; Humans; Middle Aged; Potassium; Urea | 1995 |
(+/-)-trans-2-[3-methoxy-4-(4-chlorophenylthioethoxy)-5-(N-methyl-N- hydroxyureidyl)methylphenyl]-5-(3,4, 5-trimethoxyphenyl)tetrahydrofuran (CMI-392), a potent dual 5-lipoxygenase inhibitor and platelet-activating factor receptor antagonist.
Topics: Animals; Arachidonic Acid; Blood Platelets; Cell Membrane; CHO Cells; Cricetinae; Drug Evaluation, P | 1998 |
Massive reduction of urea transporters in remnant kidney and brain of uremic rats.
Topics: Animals; Antibody Specificity; Blotting, Northern; Blotting, Western; Brain; Carrier Proteins; Creat | 2000 |
Anti-inflammatory activities of LDP-392, a dual PAF receptor antagonist and 5-lipoxygenase inhibitor.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Dose-Response Relatio | 2001 |
Nephrotic syndrome in indian children.
Topics: Adolescent; Age Factors; Amyloidosis; Child; Child, Preschool; Edema; Female; Glomerulonephritis; He | 1975 |
[Dangers of a wrong diet in patients with renal insufficiency in the predialytic state or during chronic hemodialysis].
Topics: Amino Acids; Anemia; Dietary Proteins; Edema; Electrolysis; Energy Metabolism; Humans; Hyperkalemia; | 1977 |
[The treatment of severe tropical malaria].
Topics: Adrenal Cortex Hormones; Antimalarials; Dextrans; Edema; Heparin; Humans; Malaria; Microcirculation; | 1976 |
[The prevention and treatment of post-operative and post-traumatic oedema. Chemical laboratory tests on the renal tolerance of beta-aescin (reparil) (author's transl)].
Topics: Adolescent; Adult; Creatinine; Edema; Escin; Extremities; Female; Hand Injuries; Humans; Kidney; Lon | 1975 |
[Complications in null-diet].
Topics: Acetone; Adult; Allopurinol; Arrhythmias, Cardiac; Diet, Reducing; Edema; Female; Humans; Ischemic A | 1977 |
Anti-inflammatory and antiproteolytic properties of 1-(1-naphthylacetyl)-3-substituted carbamides.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Chemical Phenomena; Chemistry; Edema; Gossypium; Gra | 1976 |
Diuretics in malignant effusions and edemas of generalized cancer.
Topics: Ascites; Body Weight; Bumetanide; Diuretics; Drinking; Edema; Furosemide; Humans; Neoplasms; Pleuris | 1976 |
[Studies on the influence of an artifically induced inflammatory reaction by creatinine, urea and guanidine injection (author's transl)].
Topics: Animals; Creatinine; Disease Models, Animal; Drug Antagonism; Drug Interactions; Edema; Formaldehyde | 1975 |
Evaluation of hemodialysis efficiency by an edema fluid model.
Topics: Adult; Aged; Creatinine; Edema; Extracellular Space; Humans; Kidney Failure, Chronic; Middle Aged; R | 1992 |
Syntheses, antiinflammatory, and analgesic activities of arylbiurets.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biuret; Chemical Phenomena; Chemistry; Edema; Male | 1990 |
Auditory dehydration testing: glycerol versus urea.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Edema; Female; Glycerol; Hearing Loss, Functional; | 1986 |
Treatment of hyponatremic cirrhosis with ascites resistant to diuretics by urea.
Topics: Adult; Ascites; Body Weight; Creatinine; Drug Therapy, Combination; Edema; Furosemide; Humans; Hypon | 1986 |
Use of urea for treatment of water retention in hyponatraemic cirrhosis with ascites resistant to diuretics.
Topics: Diuretics; Edema; Female; Humans; Hyponatremia; Liver Cirrhosis, Alcoholic; Middle Aged; Urea | 1985 |
Effect of urea on endolymphatic hydrops in guinea pigs.
Topics: Animals; Cochlea; Ear, Inner; Edema; Endolymphatic Duct; Endolymphatic Sac; Female; Guinea Pigs; Lab | 1985 |
Fluid and electrolyte status in tetanus.
Topics: Acute Disease; Blood Volume; Body Fluids; Calcium; Carbon Dioxide; Chlorides; Edema; Extracellular S | 1970 |
Diagnosis, characterization and management of post-obstructive diuresis.
Topics: Aged; Creatinine; Desoxycorticosterone; Diuresis; Edema; Heart Failure; Humans; Hypertension; Infusi | 1973 |
[The acute ischemic syndrome. Physiopathology].
Topics: Acidosis; Acute Disease; Anuria; Blood Vessels; Cognition Disorders; Edema; Extremities; Humans; Hyp | 1974 |
[Chemical constitution and teratogenic effect in rats. II. N-alkylurea, N-alkylsulfonamide, N,N-dialkylacetamide, N-methylthioacetamide, chloracetamide].
Topics: Abnormalities, Drug-Induced; Amides; Animals; Chemical Phenomena; Chemistry; Edema; Embryo, Mammalia | 1969 |
Tuberculosis as a continuing cause of renal amyloidosis.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Amyloidosis; Arthritis, Rheumatoid; Autopsy; Biopsy; C | 1974 |
Lupus nephritis: response to azathioprine.
Topics: Adolescent; Azathioprine; Edema; Female; Glomerular Filtration Rate; Glomerulonephritis; Hematuria; | 1974 |
Clinical experience with amiloride in the elderly.
Topics: Age Factors; Aged; Amiloride; Calcium; Creatinine; Diuretics; Edema; Heart Failure; Humans; Hydrazin | 1973 |
The scientific development of clinical chemistry to 1948.
Topics: Albuminuria; Animals; Biochemistry; Blood; Blood Glucose; Chemistry, Clinical; Colorimetry; Edema; E | 1973 |
Plasma biochemistry in relation to oedema of pregnancy.
Topics: Blood Protein Electrophoresis; Blood Proteins; Chlorides; Contraceptives, Oral; Edema; Erythrocytes; | 1972 |
Weight gain and chemical changes in low birthweight infants after change from human milk to modified cow's milk.
Topics: Animals; Birth Weight; Body Weight; Breast Feeding; Calcium; Edema; Growth; Homeostasis; Humans; Inf | 1972 |
Wegener's granulomatosis causing deafness.
Topics: Adult; Blood Transfusion; Conjunctivitis; Deafness; Diarrhea; Dyspnea; Ear; Edema; Eosinophils; Face | 1973 |
Use of a new diuretic agent (metolazone) in patients with edema and ascites.
Topics: Ascites; Blood Urea Nitrogen; Creatinine; Diuretics; Edema; Furosemide; Humans; Injections, Intraven | 1973 |
Experimental amyloidosis in hamsters.
Topics: Amyloidosis; Animals; Blood Proteins; Cricetinae; Diphtheria Toxoid; Disease Models, Animal; Edema; | 1973 |
Variants of citrullinaemia.
Topics: Amino Acid Metabolism, Inborn Errors; Amino Acids; Ammonia; Brain; Chromatography; Citrulline; Dyspn | 1973 |
Salt-poor human albumin in management of nephrotic syndrome.
Topics: Adolescent; Adult; Aged; Albumins; Body Weight; Creatinine; Diet Therapy; Dietary Proteins; Edema; F | 1974 |
Haemolytic-uraemic syndrome. Epidemiological and clinical study.
Topics: Adolescent; Age Factors; Antibodies, Viral; Blood; Child; Child, Preschool; Diarrhea; Edema; Feces; | 1974 |
Intestinal ammonia in uraemia: the effect of a urease inhibitor, acetohydroxamic acid.
Topics: Ammonia; Animals; Blood Proteins; Cecum; Colitis; Colon; Edema; Erythrocytes; Hydroxamic Acids; Infl | 1972 |
Chronic glomerulonephritis and the nephrotic syndrome induced in rats with N,N'-diacetylbenzidine.
Topics: Anemia; Animals; Basement Membrane; Biphenyl Compounds; Blood Protein Electrophoresis; Capillaries; | 1971 |
Derivatives of 2-aminooxazoles showing antiinflammatory activity.
Topics: Administration, Oral; Amides; Animals; Anti-Inflammatory Agents; Arthritis; Central Nervous System; | 1971 |
The nephrotic syndrome in very young infants.
Topics: Basement Membrane; Cholesterol; Cyclophosphamide; Edema; Female; Humans; Infant; Infant, Newborn; Ki | 1971 |
Functional capacity of the isolated perfused dog kidney.
Topics: Animals; Creatinine; Diet, Sodium-Restricted; Diuresis; Dogs; Edema; Glomerular Filtration Rate; In | 1967 |
[Comparative animal experiment studies by means of new technical measuring procedures for the examination of the clearing-up effect of various osmotic substances in corneal edema].
Topics: Animals; Ascorbic Acid; Cornea; Corneal Opacity; Edema; Glucose; Glycerol; Mannitol; Methylcellulose | 1969 |
["Rheomacrodex 10 per cent with Sorbit 20 per cent" in acute brain and spinal cord edema].
Topics: Acute Disease; Blood Pressure; Blood Viscosity; Brain Edema; Brain Injuries; Dextrans; Diuretics; Ed | 1967 |
[Clinical study of a new diuretic with potassium saving effect: amiloride chlorhydrate (M.K. 870)].
Topics: Adult; Aged; Edema; Ethacrynic Acid; Humans; Middle Aged; Potassium Deficiency; Urea | 1968 |
The effect of stress and of mild dehydration on renal solute output in angioneurotic and periodic oedema.
Topics: Adult; Angioedema; Biological Transport; Dehydration; Edema; Female; Humans; Kidney; Male; Psychophy | 1969 |
Biomathematical analysis of renal function.
Topics: Aged; Aminohippuric Acids; Diuresis; Diuretics; Edema; Humans; Kidney; Kidney Function Tests; Mathem | 1965 |
Treatment of postoperative cataract complications by osmotic agents.
Topics: Aged; Cataract Extraction; Cornea; Edema; Eye Diseases; Female; Glycerol; Humans; Male; Mannitol; Os | 1966 |