urea has been researched along with Eczema in 32 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Eczema: A pruritic papulovesicular dermatitis occurring as a reaction to many endogenous and exogenous agents (Dorland, 27th ed).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an open multicentre drug monitoring survey, 1611 patients with atopic dermatitis, contact eczema, dry eczema, psoriasis and pruritus were treated with a preparation containing 5% urea and 3% polidocanol (laurylmacrogol)." | 7.69 | Results of a postmarketing drug monitoring survey with a polidocanol-urea preparation for dry, itching skin. ( Freitag, G; Höppner, T, 1997) |
| "Topical vehicles containing urea are increasingly used in dermatology because of their favorable pharmacological properties, which are due to the following capacities of urea: (1) its beneficial influence on the structure and physiology of the skin, and (2) its therapeutic effect in combination with other topically active agents in various skin diseases, such as psoriasis, ichthyosis, and chronic eczema." | 4.78 | [Clinical experiences of interval treatment with dermatologic agents containing urea]. ( Antal, I; Füzesi, S; Petres, J, 1990) |
| "After 7 and 14 days of treatment, the tested urea-based cream resulted in a significant, progressive clinical improvement of xerosis and related pruritus in all patients." | 4.02 | 10% urea cream in senile xerosis: Clinical and instrumental evaluation. ( Dinotta, F; Lacarrubba, F; Micali, G; Verzì, AE, 2021) |
| "In an open multicentre drug monitoring survey, 1611 patients with atopic dermatitis, contact eczema, dry eczema, psoriasis and pruritus were treated with a preparation containing 5% urea and 3% polidocanol (laurylmacrogol)." | 3.69 | Results of a postmarketing drug monitoring survey with a polidocanol-urea preparation for dry, itching skin. ( Freitag, G; Höppner, T, 1997) |
| "Diazolidinyl urea (DU; trade name Germall II), a new broad spectrum preservative, was tested from July 1984 to September 1988 in 2400 consecutive patients with eczemas possibly caused or complicated by a contact allergy." | 3.67 | Contact sensitivity to diazolidinyl urea (Germall II). ( Happle, R; Perret, CM, 1989) |
| "Preparations containing urea were found to be effective in the treatment of ichthyosis vulgaris and so we were encouraged to test their use in other dry skin conditions." | 3.67 | [Urea as a single drug in dry skin]. ( Swanbeck, G, 1989) |
| "Urea is a hygroscopic molecule that, because of its moisturising properties, is topically used for the treatment of skin dryness at concentrations ranging from 2% to 12% in different formulations." | 1.56 | Clinical evidences of urea at low concentration. ( Lacarrubba, F; Micali, G; Nasca, MR; Puglisi, DF, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (62.50) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 2 (6.25) | 29.6817 |
| 2010's | 3 (9.38) | 24.3611 |
| 2020's | 4 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Spigariolo, CB | 1 |
| Ferrucci, SM | 1 |
| Lacarrubba, F | 3 |
| Nasca, MR | 1 |
| Puglisi, DF | 1 |
| Micali, G | 3 |
| Verzì, AE | 2 |
| Musumeci, ML | 1 |
| Dinotta, F | 1 |
| Apfelbacher, CJ | 1 |
| Ofenloch, RF | 1 |
| Weisshaar, E | 1 |
| Molin, S | 1 |
| Bauer, A | 1 |
| Mahler, V | 1 |
| Heinrich, A | 1 |
| von Kiedrowski, R | 1 |
| Schmitt, J | 1 |
| Elsner, P | 1 |
| Diepgen, TL | 1 |
| Lodén, M | 2 |
| Wirén, K | 1 |
| Smerud, K | 1 |
| Meland, N | 1 |
| Hønnås, H | 1 |
| Mørk, G | 1 |
| Lützow-Holm, C | 1 |
| Funk, J | 1 |
| Meding, B | 1 |
| Ciammaichella, G | 1 |
| Belcaro, G | 1 |
| Dugall, M | 1 |
| Hosoi, M | 1 |
| Luzzi, R | 1 |
| Ippolito, E | 1 |
| Cesarone, MR | 1 |
| Onder, M | 1 |
| Oztas, M | 1 |
| Arnavut, O | 1 |
| BURCKHARDT, W | 1 |
| BURCKHARDT, K | 1 |
| SCHWARZ-SPECK, M | 1 |
| KOLLNER, W | 1 |
| MARTINSON, EE | 1 |
| LIND, AIa | 1 |
| HALER, D | 1 |
| GISS, G | 1 |
| ROTHENBURG, W | 1 |
| Pevzner, ES | 1 |
| Filatovich, LN | 1 |
| Taube, KM | 1 |
| Zaumseil, RP | 1 |
| Wohlrab, W | 1 |
| Reiss, CJ | 1 |
| Ernst, TM | 1 |
| Proksch, E | 1 |
| Freitag, G | 1 |
| Höppner, T | 1 |
| Andersson, AC | 1 |
| Anderson, C | 1 |
| Bergbrant, IM | 1 |
| Frödin, T | 1 |
| Ohman, H | 1 |
| Sandström, MH | 1 |
| Särnhult, T | 1 |
| Voog, E | 1 |
| Stenberg, B | 1 |
| Pawlik, E | 1 |
| Preisler-Häggqvist, A | 1 |
| Svensson, A | 1 |
| Lindberg, M | 1 |
| Khan, SA | 1 |
| Petres, J | 1 |
| Antal, I | 1 |
| Füzesi, S | 1 |
| Drosner, M | 1 |
| Perret, CM | 1 |
| Happle, R | 1 |
| Swanbeck, G | 2 |
| Irons, M | 1 |
| Levy, HL | 1 |
| Hersle, K | 1 |
| Gisslén, H | 1 |
| Almeyda, J | 2 |
| Burt, BW | 1 |
| Fry, L | 1 |
| Paskova, Z | 1 |
| Hodek, B | 1 |
| Miklikova, Z | 1 |
| Hindson, TC | 1 |
| Schwarz, E | 1 |
4 reviews available for urea and Eczema
| Article | Year |
|---|---|
[Urea in dermatology].
Topics: Eczema; Humans; Psoriasis; Skin Diseases; Urea | 1994 |
[Clinical experiences of interval treatment with dermatologic agents containing urea].
Topics: Dermatologic Agents; Eczema; Humans; Neurodermatitis; Pharmaceutical Vehicles; Psoriasis; Skin; Urea | 1990 |
[Urea in combination with corticosteroids in treating eczema].
Topics: Administration, Topical; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Drug Therapy, Combinatio | 1989 |
Metabolic syndromes with dermatologic manifestations.
Topics: Albinism; Alkaptonuria; Amidohydrolases; Amino Acid Metabolism, Inborn Errors; Amino Acids; Biotinid | 1986 |
7 trials available for urea and Eczema
| Article | Year |
|---|---|
Treatment with a barrier-strengthening moisturizer prevents relapse of hand-eczema. An open, randomized, prospective, parallel group study.
Topics: Administration, Cutaneous; Adult; Aged; Eczema; Emollients; Female; Hand Dermatoses; Humans; Male; M | 2010 |
A double-blind study comparing the effect of glycerin and urea on dry, eczematous skin in atopic patients.
Topics: Administration, Topical; Adult; Aged; Dermatitis, Atopic; Dermatologic Agents; Dose-Response Relatio | 2002 |
Treatment of non-inflammatory dermatoses. A double-blind comparison of 1% hydrocortisone plus 10% urea and 0.05% fluocinonide.
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Clini | 1978 |
[Urea in combination with corticosteroids in treating eczema].
Topics: Administration, Topical; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Drug Therapy, Combinatio | 1989 |
[Calmurid HC ointment--a new principle in the treatment chronic traumiterative hand eczema].
Topics: Chronic Disease; Clinical Trials as Topic; Eczema; Female; Fluprednisolone; Hand Dermatoses; Humans; | 1972 |
Double blind controlled study of treatment of atopic eczema with a preparation of hydrocortisone in a new drug delivery system versus betamethasone 17-valerate.
Topics: Adolescent; Adult; Aged; Betamethasone; Child; Child, Preschool; Clinical Trials as Topic; Dermatiti | 1974 |
Controlled trial of the treatment of atopic eczema with a urea-hydrocortisone preparation versus betamethasone 17-valerat.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Betamethasone; Child; Ch | 1973 |
22 other studies available for urea and Eczema
| Article | Year |
|---|---|
Efficacy and tolerability of a repairing moisturizing cream containing amino-inositole and urea 10% in adults with chronic eczematous dermatitis of the hands.
Topics: Adult; Eczema; Emollients; Humans; Immunoglobulin A; Pain; Pruritus; Treatment Outcome; Urea | 2023 |
Clinical evidences of urea at low concentration.
Topics: Dermatitis, Atopic; Eczema; Humans; Skin Diseases; Urea | 2020 |
History of urea as a dermatological agent in clinical practice.
Topics: Dermatitis, Atopic; Dermatologic Agents; Eczema; Humans; Ichthyosis; Urea | 2020 |
10% urea cream in senile xerosis: Clinical and instrumental evaluation.
Topics: Aged; Eczema; Emollients; Humans; Pruritus; Treatment Outcome; Urea | 2021 |
Chronic hand eczema in Germany: 5-year follow-up data from the CARPE registry.
Topics: Acitretin; Administration, Cutaneous; Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and | 2019 |
Product evaluation of Ureadin Rx Db (ISDIN) for prevention and treatment of mild-to-moderate xerosis of the foot in diabetic patients. Prevention of skin lesions due to microangiopathy.
Topics: Administration, Cutaneous; Arginine; Carnosine; Dermatologic Agents; Diabetic Angiopathies; Diabetic | 2012 |
Nargile (Hubble-Bubble) smoking-induced hand eczema.
Topics: Adrenal Cortex Hormones; Aged; Eczema; Equipment Design; Hand Dermatoses; Humans; Male; Ointments; P | 2002 |
[Photoallergic eczemas caused by nadisan].
Topics: Dermatitis; Eczema; Sulfanilamide; Sulfanilamides; Urea | 1957 |
[On the therapy of hemorrhoids and anal eczema].
Topics: Aminosalicylic Acid; Aminosalicylic Acids; Anal Canal; Eczema; Hemorrhoids; Humans; Quinolines; Urea | 1963 |
[TROPHIC ACTION OF UREA AND ITS USE IN THE TREATMENT OF NEUROTROPHIC SKIN DISEASES].
Topics: Dermatology; Eczema; Humans; Hypersensitivity; Nerve Tissue Proteins; Skin Diseases; Urea | 1963 |
POLYNOXYLIN: A NEW ANTISEPTIC.
Topics: Acne Vulgaris; Anti-Infective Agents, Local; Drug Therapy; Eczema; Escherichia coli Infections; Hord | 1964 |
[SEBORRHEIC ECZEMA AND ITS TREATMENT WITH UREA-CONTAINING SUSPENSIONS USED IN ADDITION TO OTHER PREPARATIONS].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Dermatitis; Dermatitis, Seborrheic; Drug Therapy | 1964 |
[Experience with the use of carbamine in the treatment of eczema and neurodermitis].
Topics: Carbon Dioxide; Eczema; Humans; Injections, Intravenous; Neurodermatitis; Urea | 1966 |
[Investigation of local therapy following urea pretreatment. First results (author's transl)].
Topics: Adolescent; Adult; Aged; Anthralin; Dexamethasone; Eczema; Female; Humans; Male; Middle Aged; Premed | 1981 |
[Potentiation of hydrocortisone by admixture of urea].
Topics: Administration, Topical; Anti-Inflammatory Agents; Drug Combinations; Eczema; Female; Humans; Hydroc | 1980 |
Results of a postmarketing drug monitoring survey with a polidocanol-urea preparation for dry, itching skin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child, Preschool; Dermatitis, Atopic; Drug Combinations; | 1997 |
Contact sensitivity to diazolidinyl urea (Germall II).
Topics: Adult; Aged; Cosmetics; Dermatitis, Contact; Eczema; Female; Formaldehyde; Humans; Male; Middle Aged | 1989 |
[Urea as a single drug in dry skin].
Topics: Administration, Topical; Dermatologic Agents; Drug Therapy, Combination; Eczema; Hand Dermatoses; Hu | 1989 |
A new treatment of ichthyosis and other hyperkeratotic conditions.
Topics: Adolescent; Adult; Aged; Eczema; Female; Humans; Humidity; Ichthyosis; Male; Ointments; Psoriasis; S | 1968 |
[Experience with Lysenyl in allergology].
Topics: Adolescent; Adult; Aged; Asthma; Child; Chronic Disease; Conjunctivitis; Eczema; Ergolines; Female; | 1972 |
Urea in the topical treatment of atopic eczema.
Topics: Adult; Betamethasone; Child; Child, Preschool; Chronic Disease; Dermatologic Agents; Eczema; Foot De | 1971 |
[Free amino acids and related compounds in the scrapable horny layer of uninvolved skin in microbial eczema and subjects without skin disease].
Topics: Adolescent; Adult; Aged; Amino Acids; Ammonia; Binding Sites; Chromatography; Chromatography, Paper; | 1971 |