urea has been researched along with Diseases, Metabolic in 37 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Correction of metabolic acidosis in patients with moderate CKD attenuates the rise in blood urea and PTH, which might prevent the deleterious long-term consequences of secondary hyperparathyroidism." | 9.12 | Effects of correction of metabolic acidosis on blood urea and bone metabolism in patients with mild to moderate chronic kidney disease: a prospective randomized single blind controlled trial. ( Bhowmik, D; Dash, SC; Gupta, N; Mathur, RP; Prakash, S; Saxena, S, 2006) |
| "Correction of metabolic acidosis in patients with moderate CKD attenuates the rise in blood urea and PTH, which might prevent the deleterious long-term consequences of secondary hyperparathyroidism." | 5.12 | Effects of correction of metabolic acidosis on blood urea and bone metabolism in patients with mild to moderate chronic kidney disease: a prospective randomized single blind controlled trial. ( Bhowmik, D; Dash, SC; Gupta, N; Mathur, RP; Prakash, S; Saxena, S, 2006) |
| "Hepatocyte glycogen accumulation in urea cycle enzyme defects resembles that seen in glycogen storage disease but can be distinguished in most cases by non-uniformity of distribution and/or the absence of sinusoidal compression by expanded hepatocytes." | 3.73 | Hepatocyte glycogen accumulation in patients undergoing dietary management of urea cycle defects mimics storage disease. ( Bove, KE; Heubi, JE; Miles, L, 2005) |
| "An effective and rapid treatment of hyperammonemia is crucial to prevent irreversible neurological damage and it depends on the understanding of the pathophysiology of the diseases, as well as of the available therapeutic approaches." | 2.82 | Hyperammonemia in Inherited Metabolic Diseases. ( Deon, M; Lopes, FF; Ribas, GS; Vargas, CR, 2022) |
| "Treatment of urea cycle disorders and related metabolic diseases consists of nutritional restriction of proteins, administration of specific amino acids, and use of alternative pathways for discarding excess nitrogen." | 2.42 | Clinical manifestations of inborn errors of the urea cycle and related metabolic disorders during childhood. ( Endo, F; Matsuda, I; Matsuura, T; Yanagita, K, 2004) |
| "Hypernatremia is common in critical care, especially in severely burned patients." | 1.56 | The Link between Hypermetabolism and Hypernatremia in Severely Burned Patients. ( Kreutziger, J; Rugg, C; Schmid, S; Ströhle, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (43.24) | 18.7374 |
| 1990's | 6 (16.22) | 18.2507 |
| 2000's | 10 (27.03) | 29.6817 |
| 2010's | 2 (5.41) | 24.3611 |
| 2020's | 3 (8.11) | 2.80 |
| Authors | Studies |
|---|---|
| Ribas, GS | 1 |
| Lopes, FF | 1 |
| Deon, M | 1 |
| Vargas, CR | 1 |
| Zhou, GP | 1 |
| Li, SP | 1 |
| Jiang, YZ | 1 |
| Sun, J | 1 |
| Tan, YL | 1 |
| Zeng, ZG | 1 |
| Wei, L | 1 |
| Qu, W | 1 |
| Sun, LY | 1 |
| Zhu, ZJ | 1 |
| Rugg, C | 1 |
| Ströhle, M | 1 |
| Schmid, S | 1 |
| Kreutziger, J | 1 |
| Kuhara, T | 1 |
| Ohse, M | 1 |
| Inoue, Y | 1 |
| Shinka, T | 1 |
| Mallick, C | 1 |
| De, D | 1 |
| Ghosh, D | 1 |
| Kozmus, CE | 1 |
| Moura, E | 1 |
| Serrão, MP | 1 |
| Real, H | 1 |
| Guimarães, JT | 1 |
| Guedes-de-Pinho, P | 1 |
| Duarte, BP | 1 |
| Marques, F | 1 |
| Martins, MJ | 1 |
| Vieira-Coelho, MA | 1 |
| Bierwolf, J | 1 |
| Lutgehetmann, M | 1 |
| Deichmann, S | 1 |
| Erbes, J | 1 |
| Volz, T | 1 |
| Dandri, M | 1 |
| Cohen, S | 1 |
| Nashan, B | 1 |
| Pollok, JM | 1 |
| Lee, K | 1 |
| Berthiaume, F | 1 |
| Stephanopoulos, GN | 1 |
| Yarmush, ML | 1 |
| SRIKANTIA, SG | 1 |
| GOPALAN, C | 1 |
| ANDERSEN, M | 1 |
| FRENKEL, EP | 1 |
| SKINNER, WN | 1 |
| SMILEY, JD | 1 |
| PAMPIGLIONE, G | 1 |
| Parker, CC | 1 |
| Evans, OB | 1 |
| Endo, F | 1 |
| Matsuura, T | 1 |
| Yanagita, K | 1 |
| Matsuda, I | 1 |
| Nagasaka, H | 1 |
| Komatsu, H | 1 |
| Ohura, T | 1 |
| Sogo, T | 1 |
| Inui, A | 1 |
| Yorifuji, T | 1 |
| Murayama, K | 1 |
| Takayanagi, M | 1 |
| Kikuta, H | 1 |
| Kobayashi, K | 1 |
| Paraskevas, KI | 1 |
| Anagnostou, D | 1 |
| Bouris, C | 1 |
| Miles, L | 1 |
| Heubi, JE | 1 |
| Bove, KE | 1 |
| Mathur, RP | 1 |
| Dash, SC | 1 |
| Gupta, N | 1 |
| Prakash, S | 1 |
| Saxena, S | 1 |
| Bhowmik, D | 1 |
| Tuchman, M | 1 |
| Caldovic, L | 1 |
| Daikhin, Y | 1 |
| Horyn, O | 1 |
| Nissim, I | 2 |
| Korson, M | 1 |
| Burton, B | 1 |
| Yudkoff, M | 1 |
| De Miranda, CM | 1 |
| Takei, Y | 1 |
| Ikeda, S | 1 |
| Hansen, O | 1 |
| Wamberg, S | 1 |
| Clausen, TN | 1 |
| Bonham, JR | 2 |
| Guthrie, P | 1 |
| Downing, M | 1 |
| Allen, JC | 1 |
| Tanner, MS | 1 |
| Sharrard, M | 1 |
| Rittey, C | 1 |
| Land, JM | 1 |
| Fensom, A | 1 |
| O'Neill, D | 1 |
| Duley, JA | 1 |
| Fairbanks, LD | 1 |
| Blackburn, GL | 1 |
| Maini, BS | 1 |
| Pierce, EC | 1 |
| Kamoun, PP | 1 |
| Ridley, PD | 1 |
| Ratcliffe, JM | 1 |
| Alberti, KG | 1 |
| Elliott, MJ | 1 |
| Clarke, A | 1 |
| Gardner-Medwin, D | 1 |
| Richardson, J | 1 |
| McGann, A | 1 |
| Carpenter, KH | 1 |
| Bhattacharya, S | 1 |
| Haggerty, D | 1 |
| Fleetwood, JA | 1 |
| Aynsley-Green, A | 1 |
| Irons, M | 1 |
| Levy, HL | 1 |
| Hordinsky, MK | 1 |
| Briden, B | 1 |
| Berry, SA | 1 |
| Cormier, JM | 1 |
| Chang, TM | 1 |
| Maschio, G | 1 |
| Mioni, G | 1 |
| Liappis, N | 1 |
| Brodehl, J | 1 |
| Jäkel, A | 1 |
| Zarembski, PM | 1 |
| Rosen, SM | 1 |
| Hodgkinson, A | 1 |
| Battke, H | 1 |
| Stadie, G | 1 |
| Summerskill, WH | 1 |
| Thorsell, F | 1 |
| Feinberg, JH | 1 |
| Aldrete, JS | 1 |
| Wakim, KG | 1 |
| Johnson, WJ | 1 |
| Klass, DW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Increasing Ureagenesis in Inborn Errors of Metabolism With N-Carbamylglutamate[NCT01341379] | Phase 2 | 0 participants (Actual) | Interventional | 2010-12-31 | Withdrawn (stopped due to Lack of funding) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 reviews available for urea and Diseases, Metabolic
| Article | Year |
|---|---|
Hyperammonemia in Inherited Metabolic Diseases.
Topics: Ammonia; Fatty Acids; Humans; Hyperammonemia; Infant, Newborn; Metabolic Diseases; Urea | 2022 |
Metabolic disorders causing childhood ataxia.
Topics: Acidosis, Lactic; Amino Acid Metabolism, Inborn Errors; Glycosylation; Humans; Lysosomal Storage Dis | 2003 |
Clinical manifestations of inborn errors of the urea cycle and related metabolic disorders during childhood.
Topics: Child; Humans; Metabolic Diseases; Metabolism, Inborn Errors; Prognosis; Quaternary Ammonium Compoun | 2004 |
Anurea caused by primary amyloidosis of the lower third of the ureters, the ureterovesical junction and the urinary bladder: a case report and review of the literature.
Topics: Amyloidosis; Female; Humans; Metabolic Diseases; Middle Aged; Urea; Ureteral Diseases; Urinary Bladd | 2004 |
[Liver transplantation in metabolic diseases].
Topics: alpha 1-Antitrypsin Deficiency; Amyloid Neuropathies; Forecasting; Hepatolenticular Degeneration; Hu | 1995 |
Nutrition in the critically ill patient.
Topics: Amino Acids; Boston; Critical Care; Diabetes Mellitus; Dietary Carbohydrates; Dietary Fats; Dietary | 1977 |
[Metabolism of amino acids and urea cycle: animal models of enzymopathies].
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Disease Models, Animal; Enzymes; Metabolic Diseases; | 1992 |
Metabolic syndromes with dermatologic manifestations.
Topics: Albinism; Alkaptonuria; Amidohydrolases; Amino Acid Metabolism, Inborn Errors; Amino Acids; Biotinid | 1986 |
Immobilization of enzymes, adsorbents, or both within semipermeable microcapsules (artificial cells) for clinical and experimental treatment of metabolite-related disorders.
Topics: Acatalasia; Administration, Oral; Animals; Asparaginase; Asparagine; Catalase; Disease Models, Anima | 1973 |
2 trials available for urea and Diseases, Metabolic
| Article | Year |
|---|---|
Effects of correction of metabolic acidosis on blood urea and bone metabolism in patients with mild to moderate chronic kidney disease: a prospective randomized single blind controlled trial.
Topics: Acidosis; Adult; Aged; Bone and Bones; Chronic Disease; Female; Humans; Kidney Diseases; Male; Metab | 2006 |
N-carbamylglutamate markedly enhances ureagenesis in N-acetylglutamate deficiency and propionic acidemia as measured by isotopic incorporation and blood biomarkers.
Topics: Acetyl Coenzyme A; Adult; Amino Acids; Ammonia; Biomarkers; Carbon Dioxide; Carbon Isotopes; Child; | 2008 |
26 other studies available for urea and Diseases, Metabolic
| Article | Year |
|---|---|
Domino hepatocyte transplantation using explanted human livers with metabolic defects attenuates D-GalN/LPS-induced acute liver failure.
Topics: Alanine Transaminase; Albumins; alpha 1-Antitrypsin; Animals; Aspartate Aminotransferases; Child; Cy | 2022 |
The Link between Hypermetabolism and Hypernatremia in Severely Burned Patients.
Topics: Adult; Burns; Creatinine; Critical Illness; Diuresis; Electrolytes; Female; Humans; Hypernatremia; I | 2020 |
Five cases of beta-ureidopropionase deficiency detected by GC/MS analysis of urine metabolome.
Topics: Amidohydrolases; Gas Chromatography-Mass Spectrometry; Humans; Infant, Newborn; Japan; Metabolic Dis | 2009 |
Correction of protein metabolic disorders by composite extract of Musa paradisiaca and Coccinia indica in streptozotocin-induced diabetic albino rat: an approach through the pancreas.
Topics: Amidohydrolases; Animals; Blood Glucose; Cucurbitaceae; Diabetes Mellitus, Experimental; Glycated He | 2009 |
Influence of dietary supplementation with dextrin or oligofructose on the hepatic redox balance in rats.
Topics: Animals; Antioxidants; Biomarkers; Cholesterol; Dextrins; Fatty Acids, Volatile; Glutathione; Hypoli | 2011 |
Primary human hepatocytes from metabolic-disordered children recreate highly differentiated liver-tissue-like spheroids on alginate scaffolds.
Topics: Alginates; alpha 1-Antitrypsin; Biological Assay; Cell Differentiation; Cell Membrane; Cell Separati | 2012 |
Profiling of dynamic changes in hypermetabolic livers.
Topics: Adaptation, Physiological; Animals; Burns; Citric Acid Cycle; Computer Simulation; Energy Metabolism | 2003 |
Validity of the urea method for estimating total body-water in malnutrition.
Topics: Body Fluids; Deficiency Diseases; Metabolic Diseases; Urea | 1957 |
The effect of different pathological conditions on the excretion of urea in the rabbit kidney.
Topics: Animals; Biological Transport; Kidney; Kidney Diseases; Metabolic Diseases; Rabbits; Urea | 1961 |
STUDIES ON A METABOLIC DEFECT INDUCED BY HYDROXYUREA (NSC-32065).
Topics: Anemia; Anemia, Macrocytic; Animals; Antineoplastic Agents; Bone Marrow Cells; Cattle; Cytosine Nucl | 1964 |
ELECTROENCEPHALOGRAPHIC AND METABOLIC CHANGES AFTER SURGICAL OPERATIONS.
Topics: Bicarbonates; Blood; Child; Chlorides; Electroencephalography; Humans; Hypokalemia; Hyponatremia; Me | 1965 |
Nitric oxide synthesis in ornithine transcarbamylase deficiency: possible involvement of low no synthesis in clinical manifestations of urea cycle defect.
Topics: Child, Preschool; Female; Humans; Infant; Metabolic Diseases; Nitric Oxide; Ornithine Carbamoyltrans | 2004 |
Hepatocyte glycogen accumulation in patients undergoing dietary management of urea cycle defects mimics storage disease.
Topics: Child; Child, Preschool; Diagnosis, Differential; Glucose-6-Phosphatase; Glycogen; Glycogen Storage | 2005 |
[Cerebral edema].
Topics: Adrenal Cortex Hormones; Brain Edema; Cerebrovascular Disorders; Diuretics; Glycerol; Humans; Hydroc | 1980 |
Failure of loop diuretics to induce nursing sickness in mink at weaning.
Topics: Aldosterone; Animal Diseases; Animals; Chlorides; Creatinine; Diuretics; Female; Furosemide; Hydroco | 1996 |
The allopurinol load test lacks specificity for primary urea cycle defects but may indicate unrecognized mitochondrial disease.
Topics: Allopurinol; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Male; Metabolic Disea | 1999 |
The metabolic consequences of a "washed" cardiopulmonary bypass pump-priming fluid in children undergoing cardiac operations.
Topics: Blood Glucose; Blood Proteins; Cardiopulmonary Bypass; Child; Child, Preschool; Creatine; Electrolyt | 1990 |
Abnormalities of carbohydrate metabolism and of OCT gene function in the Rett syndrome.
Topics: Adolescent; Carbohydrate Metabolism; Child; Child, Preschool; Female; Genetic Linkage; Humans; Metab | 1990 |
Friable hair, urea cycle dysfunction, and trichothiodystrophy. A new X-linked genodermatosis.
Topics: Amino Acids; Biopsy; Genetic Linkage; Hair Diseases; Humans; Infant; Male; Metabolic Diseases; Skin; | 1987 |
[The acute ischemic syndrome. Physiopathology].
Topics: Acidosis; Acute Disease; Anuria; Blood Vessels; Cognition Disorders; Edema; Extremities; Humans; Hyp | 1974 |
[The dysmetabolic syndrome after kidney transplantation].
Topics: Acidosis, Renal Tubular; Electrolytes; Glycosuria, Renal; Humans; Hypercalcemia; Hyperparathyroidism | 1971 |
[Ammonium concentration in the venous blood of infants and children].
Topics: Adolescent; Age Factors; Ammonia; Analysis of Variance; Chemistry, Clinical; Child; Child, Preschool | 1971 |
Dialysis in the treatment of primary hyperoxaluria.
Topics: Adult; Creatinine; Female; Humans; Kidney Calculi; Metabolic Diseases; Oxalates; Peritoneal Dialysis | 1969 |
[Electrolyte disturbances after urinary diversion into the colon].
Topics: Acid-Base Equilibrium; Calcium; Chlorides; Colon; Humans; Intestinal Absorption; Magnesium; Metaboli | 1970 |
Effects of urease inhibition in hyperammonemia: clinical and experimental studies with acetohydroxamic acid.
Topics: Aged; Ammonia; Animals; Bilirubin; Budd-Chiari Syndrome; Dogs; Fasting; Female; Hepatic Encephalopat | 1968 |
Role of blood urea and serum sodium concentrations in the pathogenesis of the dialysis dysequilibrium syndrome.
Topics: Animals; Brain Chemistry; Cerebrospinal Fluid; Dogs; Electroencephalography; Hemodynamics; Humans; H | 1968 |