urea has been researched along with Dermatitis, Atopic in 41 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In an open multicentre drug monitoring survey, 1611 patients with atopic dermatitis, contact eczema, dry eczema, psoriasis and pruritus were treated with a preparation containing 5% urea and 3% polidocanol (laurylmacrogol)." | 7.69 | Results of a postmarketing drug monitoring survey with a polidocanol-urea preparation for dry, itching skin. ( Freitag, G; Höppner, T, 1997) |
| "In an open multicentre drug monitoring survey, 1611 patients with atopic dermatitis, contact eczema, dry eczema, psoriasis and pruritus were treated with a preparation containing 5% urea and 3% polidocanol (laurylmacrogol)." | 3.69 | Results of a postmarketing drug monitoring survey with a polidocanol-urea preparation for dry, itching skin. ( Freitag, G; Höppner, T, 1997) |
| "Urea is a hygroscopic molecule that, because of its moisturising properties, is topically used for the treatment of skin dryness at concentrations ranging from 2% to 12% in different formulations." | 1.56 | Clinical evidences of urea at low concentration. ( Lacarrubba, F; Micali, G; Nasca, MR; Puglisi, DF, 2020) |
| "Urea is a major component of many daily skincare products which is widely used." | 1.56 | Mode of action of urea. ( Dirschka, T, 2020) |
| "Atopic dermatitis is a chronic skin disorder with high prevalence, especially in the Nordic countries." | 1.43 | Cost-effectiveness of Maintenance Treatment with a Barrier-strengthening Moisturizing Cream in Patients with Atopic Dermatitis in Finland, Norway and Sweden. ( Hjalte, F; Lundqvist, A; Norrlid, H; Svensson, Å; Tennvall, GR, 2016) |
| "Urea is an endogenous metabolite, known to enhance stratum corneum hydration." | 1.38 | Urea uptake enhances barrier function and antimicrobial defense in humans by regulating epidermal gene expression. ( Brenden, H; Elias, PM; Felsner, I; Grether-Beck, S; Hupe, M; Jaenicke, T; Kohne, Z; Krutmann, J; Majora, M; Marini, A; Rodriguez-Martin, M; Trullas, C, 2012) |
| "Urea has anti-inflammatory, hyposensitizing, and antioxidant effect." | 1.36 | [The evaluation of nitrogen metabolism and the reactivity of the organism in patients with dry skin]. ( Katsitadze, AG; Tsiskarishvili, NI; Tsiskarishvili, NV, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (21.95) | 18.7374 |
| 1990's | 10 (24.39) | 18.2507 |
| 2000's | 8 (19.51) | 29.6817 |
| 2010's | 11 (26.83) | 24.3611 |
| 2020's | 3 (7.32) | 2.80 |
| Authors | Studies |
|---|---|
| Lacarrubba, F | 3 |
| Nasca, MR | 1 |
| Puglisi, DF | 1 |
| Micali, G | 3 |
| Verzì, AE | 1 |
| Musumeci, ML | 1 |
| Dirschka, T | 1 |
| Paternò, V | 1 |
| Cannarella, R | 1 |
| Dinotta, F | 1 |
| Hussain, H | 1 |
| Ziegler, J | 1 |
| Hause, G | 1 |
| Wohlrab, J | 1 |
| Neubert, RHH | 1 |
| Shaughnessy, CN | 1 |
| Malajian, D | 1 |
| Belsito, DV | 1 |
| Hoppe, T | 1 |
| Winge, MC | 1 |
| Bradley, M | 2 |
| Nordenskjöld, M | 1 |
| Vahlquist, A | 1 |
| Törmä, H | 1 |
| Berne, B | 1 |
| Lindh, JD | 1 |
| Norrlid, H | 1 |
| Hjalte, F | 1 |
| Lundqvist, A | 1 |
| Svensson, Å | 2 |
| Tennvall, GR | 1 |
| Shiohara, T | 1 |
| Sato, Y | 1 |
| Komatsu, Y | 1 |
| Ushigome, Y | 1 |
| Mizukawa, Y | 1 |
| Amichai, B | 1 |
| Grunwald, MH | 1 |
| Bissonnette, R | 1 |
| Maari, C | 1 |
| Provost, N | 1 |
| Bolduc, C | 1 |
| Nigen, S | 1 |
| Rougier, A | 1 |
| Seite, S | 1 |
| Tsiskarishvili, NV | 1 |
| Katsitadze, AG | 1 |
| Tsiskarishvili, NI | 1 |
| Grether-Beck, S | 1 |
| Felsner, I | 1 |
| Brenden, H | 1 |
| Kohne, Z | 1 |
| Majora, M | 1 |
| Marini, A | 1 |
| Jaenicke, T | 1 |
| Rodriguez-Martin, M | 1 |
| Trullas, C | 1 |
| Hupe, M | 1 |
| Elias, PM | 1 |
| Krutmann, J | 1 |
| Sugawara, T | 1 |
| Kikuchi, K | 1 |
| Tagami, H | 1 |
| Aiba, S | 1 |
| Sakai, S | 1 |
| Gloor, M | 1 |
| Gehring, W | 1 |
| MULLER, SA | 1 |
| KIERLAND, RR | 1 |
| Nenoff, P | 1 |
| Donaubauer, K | 1 |
| Arndt, T | 1 |
| Haustein, UF | 1 |
| Rudolph, R | 1 |
| Kownatzki, E | 1 |
| Abels, C | 1 |
| Proksch, E | 1 |
| Boyle, J | 1 |
| Kennedy, CT | 1 |
| Landes, E | 1 |
| Wolf, A | 1 |
| Schöpf, E | 2 |
| Mueller, JM | 1 |
| Ostermann, T | 1 |
| Niedner, R | 1 |
| Freitag, G | 1 |
| Höppner, T | 1 |
| Wood, RA | 1 |
| Roehr, CC | 1 |
| Reibel, S | 1 |
| Niggemann, B | 1 |
| Lodén, M | 2 |
| Andersson, AC | 2 |
| Andersson, C | 1 |
| Frödin, T | 2 |
| Oman, H | 1 |
| Lindberg, M | 2 |
| Anderson, C | 1 |
| Bergbrant, IM | 1 |
| Ohman, H | 1 |
| Sandström, MH | 1 |
| Särnhult, T | 1 |
| Voog, E | 1 |
| Stenberg, B | 1 |
| Pawlik, E | 1 |
| Preisler-Häggqvist, A | 1 |
| Andersen, KE | 1 |
| Brandrup, F | 1 |
| Jacobsen, M | 1 |
| Laurberg, G | 1 |
| Burkard, G | 1 |
| Schmitt, S | 1 |
| von Mayenburg, J | 1 |
| Schweingel, D | 1 |
| Drosner, M | 1 |
| Taube, KM | 1 |
| Stüttgen, G | 1 |
| Almeyda, J | 2 |
| Burt, BW | 1 |
| Fry, L | 1 |
| Seutter, E | 1 |
| Goedhart-de Groot, N | 1 |
| Sutorius, AH | 1 |
| Urselmann, EJ | 1 |
6 reviews available for urea and Dermatitis, Atopic
| Article | Year |
|---|---|
Evidence-based treatment of atopic dermatitis with topical moisturizers.
Topics: Administration, Cutaneous; Animals; Dermatitis, Atopic; Dermatologic Agents; Emollients; Evidence-Ba | 2018 |
Clinical Effectiveness of Moisturizers in Atopic Dermatitis and Related Disorders: A Systematic Review.
Topics: Dermatitis, Atopic; Dermatitis, Irritant; Emollients; Epidermis; Glycerol; Hand Dermatoses; Humans; | 2015 |
Sweat as an Efficient Natural Moisturizer.
Topics: Dermatitis, Atopic; Humans; Lactic Acid; Lichen Planus; Lichenoid Eruptions; Peptides; Potassium; Sk | 2016 |
[Value of adjuvant basic therapy in chronic recurrent skin diseases. Neurodermatitis atopica/psoriasis vulgaris].
Topics: Adrenal Cortex Hormones; Baths; Combined Modality Therapy; Cost-Benefit Analysis; Dermatitis, Atopic | 1995 |
Clinical efficacy of topical glucocorticoid preparations and other types of dermatics in inflammatory diseases, particularly in atopic dermatitis.
Topics: Administration, Cutaneous; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis; Dermatitis, Atopic; | 1993 |
[Paths to a rational cortisone therapy via urea supplements--countering cortisone phobia].
Topics: Administration, Topical; Anti-Inflammatory Agents; Dermatitis, Atopic; Drug Combinations; Drug Syner | 1992 |
13 trials available for urea and Dermatitis, Atopic
| Article | Year |
|---|---|
A randomized, double-blind, placebo-controlled study to evaluate the efficacy in AD of liquid soap containing 12% ammonium lactate + 20% urea.
Topics: Adolescent; Adult; Child; Child, Preschool; Dermatitis, Atopic; Double-Blind Method; Emollients; Fem | 2009 |
A double-blind study of tolerance and efficacy of a new urea-containing moisturizer in patients with atopic dermatitis.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Algorithms; Canada; Dermatitis, Atopic; Dermatol | 2010 |
[Topically applied arginine hydrochloride. Effect on urea content of stratum corneum and skin hydration in atopic eczema and skin aging].
Topics: Administration, Topical; Adult; Aged; Arginine; Biopsy; Dermatitis, Atopic; Epidermis; Female; Human | 2004 |
Instrumental and dermatologist evaluation of the effect of glycerine and urea on dry skin in atopic dermatitis.
Topics: Adult; Body Water; Dermatitis, Atopic; Double-Blind Method; Galvanic Skin Response; Glycerol; Humans | 2001 |
A double-blind study comparing the effect of glycerin and urea on dry, eczematous skin in atopic patients.
Topics: Administration, Topical; Adult; Aged; Dermatitis, Atopic; Dermatologic Agents; Dose-Response Relatio | 2002 |
[Calmuril-hydrocortisone and carbamide-hydrocortisone DAK. A comparison in the treatment of atopic dermatitis].
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Clini | 1979 |
Topical treatment with urea-hydrocortisone in atopic dermatitis. A controlled study against betamethasone 17-valerate.
Topics: Administration, Topical; Anti-Inflammatory Agents; Betamethasone; Betamethasone Valerate; Burns, Che | 1975 |
[Long-term study "Neurodermatitis therapy using urea-containing Externa"].
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Child; Child, Preschool; Derma | 1992 |
[Long-term study "Neurodermatitis therapy using urea-containing Externa". Experience report of a dermatologist].
Topics: Administration, Topical; Adult; Anti-Inflammatory Agents; Dermatitis, Atopic; Drug Combinations; Fem | 1992 |
[Long-term study "Neurodermatitis therapy using urea-containing Externa". Experience report of a pediatrician].
Topics: Administration, Topical; Anti-Inflammatory Agents; Child; Child, Preschool; Dermatitis, Atopic; Drug | 1992 |
Carbamide in hyperkeratosis.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Dermatitis, Atopic; Eval | 1973 |
Double blind controlled study of treatment of atopic eczema with a preparation of hydrocortisone in a new drug delivery system versus betamethasone 17-valerate.
Topics: Adolescent; Adult; Aged; Betamethasone; Child; Child, Preschool; Clinical Trials as Topic; Dermatiti | 1974 |
Controlled trial of the treatment of atopic eczema with a urea-hydrocortisone preparation versus betamethasone 17-valerat.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Betamethasone; Child; Ch | 1973 |
22 other studies available for urea and Dermatitis, Atopic
| Article | Year |
|---|---|
Clinical evidences of urea at low concentration.
Topics: Dermatitis, Atopic; Eczema; Humans; Skin Diseases; Urea | 2020 |
History of urea as a dermatological agent in clinical practice.
Topics: Dermatitis, Atopic; Dermatologic Agents; Eczema; Humans; Ichthyosis; Urea | 2020 |
Mode of action of urea.
Topics: Dermatitis, Atopic; Humans; Ichthyosis; Psoriasis; Skin; Urea | 2020 |
Quantitative Analysis of Free Amino Acids and Urea Derived from Isolated Corneocytes of Healthy Young, Healthy Aged, and Diseased Skin.
Topics: Adolescent; Adult; Aged; Amino Acids; Dermatitis, Atopic; Female; Humans; Male; Middle Aged; Psorias | 2019 |
Cutaneous delayed-type hypersensitivity in patients with atopic dermatitis: reactivity to topical preservatives.
Topics: Dermatitis, Allergic Contact; Dermatitis, Atopic; Dermatologic Agents; Female; Humans; Hydantoins; I | 2014 |
Moisturizing treatment of patients with atopic dermatitis and ichthyosis vulgaris improves dry skin, but has a modest effect on gene expression regardless of FLG genotype.
Topics: Biomarkers; Dermatitis, Atopic; Filaggrin Proteins; Forearm; Gene Expression; Gene Expression Profil | 2015 |
Cost-effectiveness of Maintenance Treatment with a Barrier-strengthening Moisturizing Cream in Patients with Atopic Dermatitis in Finland, Norway and Sweden.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cost Savings; Cost-Benefit Analysis; Dermatitis, Atopic; | 2016 |
[The evaluation of nitrogen metabolism and the reactivity of the organism in patients with dry skin].
Topics: Adolescent; Adult; Dermatitis, Atopic; Desiccation; Filaggrin Proteins; Humans; Ichthyosis; Immunogl | 2010 |
Urea uptake enhances barrier function and antimicrobial defense in humans by regulating epidermal gene expression.
Topics: Adult; Animals; Antimicrobial Cationic Peptides; Aquaporin 3; Aquaporins; Cell Differentiation; Cell | 2012 |
Decreased lactate and potassium levels in natural moisturizing factor from the stratum corneum of mild atopic dermatitis patients are involved with the reduced hydration state.
Topics: Administration, Topical; Adult; Body Water; Case-Control Studies; Dermatitis, Atopic; Epidermis; Fat | 2012 |
[Effects of emulsions on the stratum corneum barrier and hydration].
Topics: Body Water; Cell Membrane Permeability; Dermatitis, Atopic; Emulsions; Epidermis; Glycerol; Humans; | 2003 |
CRUDE COAL TAR IN DERMATOLOGIC THERAPY.
Topics: Blood Chemical Analysis; Coal Tar; Creatine; Creatinine; Dermatitis; Dermatitis, Atopic; Humans; Kid | 1964 |
Corneometric, sebumetric and TEWL measurements following the cleaning of atopic skin with a urea emulsion versus a detergent cleanser.
Topics: Adult; Dermatitis, Atopic; Detergents; Epidermis; Female; Galvanic Skin Response; Humans; Lipids; Ma | 2004 |
[Therapy of atopic dermatitis].
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Calcineurin Inhibitors; Child; Combined Modality Therap | 2006 |
Contact urticaria and dermatitis to Alphaderm.
Topics: Administration, Topical; Anti-Inflammatory Agents; Dermatitis, Atopic; Drug Combinations; Drug Erupt | 1984 |
[3-phase therapy. A contribution to the treatment of neurodermatitis atopica (endogenous eczema)].
Topics: Administration, Topical; Anti-Inflammatory Agents; Biological Availability; Dermatitis, Atopic; Drug | 1984 |
Results of a postmarketing drug monitoring survey with a polidocanol-urea preparation for dry, itching skin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child, Preschool; Dermatitis, Atopic; Drug Combinations; | 1997 |
Indoor allergens: thrill of victory or agony of defeat?
Topics: Air Pollution, Indoor; Allantoin; Allergens; Animals; Asthma; Benzoates; Cats; Collagen; Dermatitis, | 1997 |
Children with food allergy presenting as atopic dermatitis (AD) were compared with patients with food allergy and gastrointestinal symptoms.
Topics: Breath Tests; Dermatitis, Atopic; Helicobacter Infections; Helicobacter pylori; Humans; Infant; Urea | 2001 |
[Moisture retaining effect and tolerance of urea-containing Externa in neurodermatitis patients].
Topics: Dermatitis, Atopic; Humans; Ointments; Sweating; Urea; Water Loss, Insensible | 1992 |
[Results and consequences of long-term urea therapy for clinical practice].
Topics: Administration, Topical; Anti-Inflammatory Agents; Dermatitis, Atopic; Drug Combinations; Humans; Hy | 1992 |
The quantitative analysis of some constituents of crude sweat.
Topics: Ammonia; Calcium; Chlorides; Chromium; Dermatitis, Atopic; Dermatitis, Contact; Humans; Hydrogen-Ion | 1970 |