Page last updated: 2024-10-21

urea and Cognition Disorders

urea has been researched along with Cognition Disorders in 17 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"Approaches, such as vasopressin receptor antagonists or urea, have been shown to reverse moderate hyponatremia."4.89Hyponatremia: an update on current pharmacotherapy. ( Schrier, RW; Shchekochikhin, D; Tkachenko, O, 2013)
"PD psychosis is often associated with cognitive impairment, including dementia, and involves dopaminergic, serotonergic, and cholinergic mechanisms."2.87Pimavanserin for Parkinson's Disease psychosis: Effects stratified by baseline cognition and use of cognitive-enhancing medications. ( Andersson, C; Ballard, C; Coate, B; Espay, AJ; Factor, SA; Fredericks, D; Friedman, JH; Guskey, MT; Lang, AE; Larsen, NJ; Norton, JC; Vizcarra, JA; Weintraub, D, 2018)
"Neuropsychiatric symptoms are common in Alzheimer's disease (AD) and other neurodegenerative disorders."2.52Trial design innovations: Clinical trials for treatment of neuropsychiatric symptoms in Alzheimer's Disease. ( Cummings, J; Zhong, K, 2015)
" Further study is needed to determine whether these results concerning mechanism and dosage can be the basis for prevention of the development of CIS in at risk populations."1.38Prevention of the phencyclidine-induced impairment in novel object recognition in female rats by co-administration of lurasidone or tandospirone, a 5-HT(1A) partial agonist. ( Adelekun, AE; Hannaway, KE; Horiguchi, M; Jayathilake, K; Meltzer, HY, 2012)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19903 (17.65)18.7374
1990's1 (5.88)18.2507
2000's3 (17.65)29.6817
2010's10 (58.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Espay, AJ1
Guskey, MT1
Norton, JC1
Coate, B1
Vizcarra, JA1
Ballard, C1
Factor, SA1
Friedman, JH1
Lang, AE1
Larsen, NJ1
Andersson, C1
Fredericks, D1
Weintraub, D1
Geraghty, AC1
Gibson, EM1
Ghanem, RA1
Greene, JJ1
Ocampo, A1
Goldstein, AK1
Ni, L1
Yang, T1
Marton, RM1
Paşca, SP1
Greenberg, ME1
Longo, FM1
Monje, M1
Shchekochikhin, D1
Tkachenko, O1
Schrier, RW1
Gurkoff, GG1
Feng, JF1
Van, KC1
Izadi, A1
Ghiasvand, R1
Shahlaie, K1
Song, M1
Lowe, DA1
Zhou, J1
Lyeth, BG1
Cummings, J1
Zhong, K1
Enns, GM1
Mehta, MA1
Gore-Langton, E1
Golembo, N1
Colvert, E1
Williams, SC1
Sonuga-Barke, E1
Labudda, K1
Brand, M1
Mertens, M1
Ebner, A1
Markowitsch, HJ1
Woermann, FG1
Marquis, KL1
Comery, TA1
Jow, F1
Navarra, RL1
Grauer, SM1
Pulicicchio, C1
Kelley, C1
Brennan, JA1
Roncarati, R1
Scali, C1
Haydar, S1
Ghiron, C1
Terstappen, GC1
Dunlop, J1
Horiguchi, M1
Hannaway, KE1
Adelekun, AE1
Jayathilake, K1
Meltzer, HY1
King, MR1
Anderson, NJ1
Guernsey, LS1
Jolivalt, CG1
Gropman, AL1
Batshaw, ML2
Faghih, R1
Gfesser, GA1
Gopalakrishnan, M1
O'Keeffe, ST1
Lavan, JN1
Msall, M1
Monahan, PS1
Chapanis, N1
Schydlo, R1
Cormier, JM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Adverse Effects of Subcutaneous vs Intravenous Hydration on Older Acutely Admitted Patients: An Assessor-blinded, Non-inferiority RCT[NCT03710408]51 participants (Actual)Interventional2019-01-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for urea and Cognition Disorders

ArticleYear
Hyponatremia: an update on current pharmacotherapy.
    Expert opinion on pharmacotherapy, 2013, Volume: 14, Issue:6

    Topics: Aged; Antidiuretic Hormone Receptor Antagonists; Brain Edema; Chronic Disease; Clinical Trials as To

2013
Trial design innovations: Clinical trials for treatment of neuropsychiatric symptoms in Alzheimer's Disease.
    Clinical pharmacology and therapeutics, 2015, Volume: 98, Issue:5

    Topics: Alzheimer Disease; Apathy; Citalopram; Clinical Trials as Topic; Cognition Disorders; Humans; Mental

2015
Neurologic damage and neurocognitive dysfunction in urea cycle disorders.
    Seminars in pediatric neurology, 2008, Volume: 15, Issue:3

    Topics: Brain Edema; Carbamoyl-Phosphate Synthase I Deficiency Disease; Cognition Disorders; Glutamine; Huma

2008
Cognitive outcome in urea cycle disorders.
    Molecular genetics and metabolism, 2004, Volume: 81 Suppl 1

    Topics: Age of Onset; Child; Cognition Disorders; Female; Humans; Hyperammonemia; Intellectual Disability; M

2004
Advances in the discovery of novel positive allosteric modulators of the alpha7 nicotinic acetylcholine receptor.
    Recent patents on CNS drug discovery, 2007, Volume: 2, Issue:2

    Topics: Allosteric Regulation; alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds,

2007
Cognitive development in children with inborn errors of urea synthesis.
    Acta paediatrica Japonica : Overseas edition, 1988, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Cognition Disorder

1988

Trials

2 trials available for urea and Cognition Disorders

ArticleYear
Pimavanserin for Parkinson's Disease psychosis: Effects stratified by baseline cognition and use of cognitive-enhancing medications.
    Movement disorders : official journal of the Movement Disorder Society, 2018, Volume: 33, Issue:11

    Topics: Aged; Aged, 80 and over; Antipsychotic Agents; Cognition Disorders; Double-Blind Method; Female; Hum

2018
Subcutaneous fluids in elderly hospital patients with cognitive impairment.
    Gerontology, 1996, Volume: 42, Issue:1

    Topics: Aged; Aged, 80 and over; Cognition Disorders; Confusion; Costs and Cost Analysis; Creatinine; Female

1996

Other Studies

9 other studies available for urea and Cognition Disorders

ArticleYear
Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment.
    Neuron, 2019, 07-17, Volume: 103, Issue:2

    Topics: Animals; Brain-Derived Neurotrophic Factor; Cerebral Cortex; Channelrhodopsins; Cognition Disorders;

2019
NAAG peptidase inhibitor improves motor function and reduces cognitive dysfunction in a model of TBI with secondary hypoxia.
    Brain research, 2013, Jun-17, Volume: 1515

    Topics: Animals; Brain Injuries; Cognition Disorders; Disease Models, Animal; Glutamate Carboxypeptidase II;

2013
Hyporesponsive reward anticipation in the basal ganglia following severe institutional deprivation early in life.
    Journal of cognitive neuroscience, 2010, Volume: 22, Issue:10

    Topics: Adolescent; Analysis of Variance; Basal Ganglia; Carbamide Peroxide; Case-Control Studies; Cognition

2010
Alterations of decision making and underlying neural correlates after resection of a mediofrontal cortical dysplasia: A single case study.
    Neurocase, 2010, Volume: 16, Issue:1

    Topics: Attention; Brain Mapping; Carbamide Peroxide; Cognition Disorders; Decision Making; Executive Functi

2010
Preclinical assessment of an adjunctive treatment approach for cognitive impairment associated with schizophrenia using the alpha7 nicotinic acetylcholine receptor agonist WYE-103914/SEN34625.
    Psychopharmacology, 2011, Volume: 218, Issue:4

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antipsychotic Agents; Avoidance Learning; Cognitio

2011
Prevention of the phencyclidine-induced impairment in novel object recognition in female rats by co-administration of lurasidone or tandospirone, a 5-HT(1A) partial agonist.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012, Volume: 37, Issue:10

    Topics: Animals; Cognition Disorders; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Female; Halo

2012
Glycogen synthase kinase-3 inhibition prevents learning deficits in diabetic mice.
    Journal of neuroscience research, 2013, Volume: 91, Issue:4

    Topics: Animals; Cerebral Cortex; Cognition Disorders; Diabetes Mellitus, Experimental; Female; Glycogen Syn

2013
[Heavy intoxication as a side-effect of CARBROMAL in two children (author's transl)].
    Klinische Padiatrie, 1974, Volume: 186, Issue:3

    Topics: Ataxia; Basal Ganglia Diseases; Child, Preschool; Cognition Disorders; Gait; Humans; Infant; Male; M

1974
[The acute ischemic syndrome. Physiopathology].
    Revue de chirurgie orthopedique et reparatrice de l'appareil moteur, 1974, Volume: 60 Suppl 2, Issue:0

    Topics: Acidosis; Acute Disease; Anuria; Blood Vessels; Cognition Disorders; Edema; Extremities; Humans; Hyp

1974