urea has been researched along with Chronic Pain in 2 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Chronic Pain: Aching sensation that persists for more than a few months. It may or may not be associated with trauma or disease, and may persist after the initial injury has healed. Its localization, character, and timing are more vague than with acute pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "TrkA is a target for chronic pain treatment due to the central position of the nerve growth factor (NGF)/TrkA pathway in nociception." | 1.43 | Evaluation of WO2015042088 A1 - a novel urea-based scaffold for TrkA inhibition. ( Bernard-Gauthier, V; Schirrmacher, R, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stachel, SJ | 1 |
| Sanders, JM | 1 |
| Henze, DA | 1 |
| Rudd, MT | 1 |
| Su, HP | 1 |
| Li, Y | 1 |
| Nanda, KK | 1 |
| Egbertson, MS | 1 |
| Manley, PJ | 1 |
| Jones, KL | 1 |
| Brnardic, EJ | 1 |
| Green, A | 1 |
| Grobler, JA | 1 |
| Hanney, B | 1 |
| Leitl, M | 1 |
| Lai, MT | 1 |
| Munshi, V | 1 |
| Murphy, D | 1 |
| Rickert, K | 1 |
| Riley, D | 1 |
| Krasowska-Zoladek, A | 1 |
| Daley, C | 1 |
| Zuck, P | 1 |
| Kane, SA | 1 |
| Bilodeau, MT | 1 |
| Bernard-Gauthier, V | 1 |
| Schirrmacher, R | 1 |
2 other studies available for urea and Chronic Pain
| Article | Year |
|---|---|
Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain.
Topics: Animals; Chronic Pain; Drug Evaluation, Preclinical; Humans; Indoles; Ligands; Models, Molecular; Pr | 2014 |
Evaluation of WO2015042088 A1 - a novel urea-based scaffold for TrkA inhibition.
Topics: Chronic Pain; Drug Design; Humans; Inflammation; Inhibitory Concentration 50; Neoplasms; Neuralgia; | 2016 |