urea has been researched along with Cerebral Malaria in 8 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cerebral oedema occurs with cerebral malaria, and some clinicians think osmotic diuretics, such as mannitol or urea, may improve outcomes." | 8.87 | Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria. ( Afolabi, BB; Okoromah, CA; Wall, EC, 2011) |
| "To compare mannitol or urea to placebo or no treatment for treating children and adults with cerebral malaria." | 8.82 | Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria. ( Afolabi, BB; Okoromah, CA, 2004) |
| "Clinical and model studies indicate that low nitric oxide (NO) bioavailability due in part to profound hypoargininemia contributes to cerebral malaria (CM) pathogenesis." | 7.91 | Citrulline protects mice from experimental cerebral malaria by ameliorating hypoargininemia, urea cycle changes and vascular leak. ( Caparros-Wanderley, W; Chang, YS; Combes, V; Gramaglia, I; Grau, G; Stins, MF; van der Heyde, HC; Velez, J, 2019) |
| "Cerebral oedema occurs with cerebral malaria, and some clinicians think osmotic diuretics, such as mannitol or urea, may improve outcomes." | 4.87 | Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria. ( Afolabi, BB; Okoromah, CA; Wall, EC, 2011) |
| "To compare mannitol or urea to placebo or no treatment for treating children and adults with cerebral malaria." | 4.82 | Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria. ( Afolabi, BB; Okoromah, CA, 2004) |
| "Clinical and model studies indicate that low nitric oxide (NO) bioavailability due in part to profound hypoargininemia contributes to cerebral malaria (CM) pathogenesis." | 3.91 | Citrulline protects mice from experimental cerebral malaria by ameliorating hypoargininemia, urea cycle changes and vascular leak. ( Caparros-Wanderley, W; Chang, YS; Combes, V; Gramaglia, I; Grau, G; Stins, MF; van der Heyde, HC; Velez, J, 2019) |
| "We evaluated plasma creatinine, urea, bilirubin, lactic acid, and nitric oxide values in children with malaria to identify indices of disease severity and predictors of fatal outcomes." | 3.75 | Physiopathologic factors resulting in poor outcome in childhood severe malaria in Cameroon. ( Amvam Z, PH; Combes, V; Fotso K, H; Gouado, I; Grau, GE; Nguélé, S; Pankoui M, JB; Zambou, O, 2009) |
| " The factors are more common in cases with high mortality with diastolic blood pressure (DBP) below 60 mm of Hg, anaemia, persistence of Glasgow Coma Score below 5 on day 2, high parasite count at presentation, proteinuria and high level of serum urea." | 3.70 | Cerebral malaria--a study of 104 cases. ( Faiz, MA; Hossain, MA; Rahman, MR; Rashid, HA, 1998) |
| "Cerebral involvement in children with cerebral malaria is only one, though the most important, manifestation of a multi-organ disease." | 1.30 | Biochemical and haematological variables in Gambian children with cerebral malaria. ( Enwere, GC; Greenwood, BM; Jaiteh, B; Onyiorah, E; Palmer, A; Schneider, G; Van Hensbroek, MB; Weber, MW, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Bi, D | 3 |
| Lin, J | 3 |
| Luo, X | 6 |
| Lin, L | 3 |
| Tang, X | 3 |
| Lu, Y | 3 |
| Huang, X | 3 |
| Gramaglia, I | 1 |
| Velez, J | 1 |
| Chang, YS | 1 |
| Caparros-Wanderley, W | 1 |
| Combes, V | 2 |
| Grau, G | 1 |
| Stins, MF | 1 |
| van der Heyde, HC | 1 |
| Gouado, I | 1 |
| Pankoui M, JB | 1 |
| Fotso K, H | 1 |
| Zambou, O | 1 |
| Nguélé, S | 1 |
| Grau, GE | 1 |
| Amvam Z, PH | 1 |
| Okoromah, CA | 2 |
| Afolabi, BB | 2 |
| Wall, EC | 1 |
| Jaffar, S | 1 |
| Van Hensbroek, MB | 2 |
| Palmer, A | 2 |
| Schneider, G | 2 |
| Greenwood, B | 1 |
| Faiz, MA | 1 |
| Rahman, MR | 1 |
| Hossain, MA | 1 |
| Rashid, HA | 1 |
| Enwere, GC | 1 |
| Jaiteh, B | 1 |
| Onyiorah, E | 1 |
| Weber, MW | 1 |
| Greenwood, BM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Mannitol as Adjunct Therapy on the Clinical Outcome of Childhood Cerebral Malaria in Mulago Hospital: A Randomised Clinical Trial[NCT00113854] | Phase 3 | 156 participants | Interventional | 2004-10-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for urea and Cerebral Malaria
| Article | Year |
|---|---|
Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria.
Topics: Adult; Antimalarials; Child; Diuretics, Osmotic; Humans; Malaria, Cerebral; Mannitol; Quinine; Rando | 2011 |
Mannitol and other osmotic diuretics as adjuncts for treating cerebral malaria.
Topics: Adult; Child; Diuretics, Osmotic; Humans; Malaria, Cerebral; Mannitol; Urea | 2004 |
6 other studies available for urea and Cerebral Malaria
| Article | Year |
|---|---|
Biochemical characteristics of patients with imported malaria.
Topics: Albumins; Cohort Studies; Communicable Diseases, Imported; Creatinine; Ferritins; Humans; Hydroxybut | 2022 |
Biochemical characteristics of patients with imported malaria.
Topics: Albumins; Cohort Studies; Communicable Diseases, Imported; Creatinine; Ferritins; Humans; Hydroxybut | 2022 |
Biochemical characteristics of patients with imported malaria.
Topics: Albumins; Cohort Studies; Communicable Diseases, Imported; Creatinine; Ferritins; Humans; Hydroxybut | 2022 |
Biochemical characteristics of patients with imported malaria.
Topics: Albumins; Cohort Studies; Communicable Diseases, Imported; Creatinine; Ferritins; Humans; Hydroxybut | 2022 |
Citrulline protects mice from experimental cerebral malaria by ameliorating hypoargininemia, urea cycle changes and vascular leak.
Topics: Animals; Arginase; Arginine; Blood-Brain Barrier; Citrulline; Dietary Supplements; Disease Models, A | 2019 |
Physiopathologic factors resulting in poor outcome in childhood severe malaria in Cameroon.
Topics: Bilirubin; Biomarkers; Cameroon; Child; Child, Preschool; Creatinine; Female; Humans; Infant; Infant | 2009 |
Predictors of a fatal outcome following childhood cerebral malaria.
Topics: Age Factors; Analysis of Variance; Child; Child, Preschool; Coma; Female; Gambia; Humans; Hypoglycem | 1997 |
Cerebral malaria--a study of 104 cases.
Topics: Adult; Anemia; Animals; Cause of Death; Coma; Endemic Diseases; Female; Fever; Glasgow Coma Scale; H | 1998 |
Biochemical and haematological variables in Gambian children with cerebral malaria.
Topics: Blood Cell Count; Child; Child, Preschool; Creatinine; Electrolytes; Female; Humans; Infant; Kidney; | 1999 |