Page last updated: 2024-10-21

urea and Cell Transformation, Neoplastic

urea has been researched along with Cell Transformation, Neoplastic in 19 studies

pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"The ANFT-treated cells followed by control medium or urea and cells treated with ANFT, NaS and urea were tumorigenic when transplanted to nude mice, whereas NaS or ANFT followed by NaS treatment were not."1.28In vitro transformation of rat bladder epithelium by 2-amino-4-(5-nitro-2-furyl)thiazole. ( Borgeson, CD; Chlapowski, FJ; Cohen, SM; Mann, AM; Masui, T; Okamura, T, 1991)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199014 (73.68)18.7374
1990's2 (10.53)18.2507
2000's1 (5.26)29.6817
2010's1 (5.26)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Hajaj, E1
Sciacovelli, M1
Frezza, C1
Erez, A1
Eder, M1
Schäfer, M1
Bauder-Wüst, U1
Hull, WE1
Wängler, C1
Mier, W1
Haberkorn, U1
Eisenhut, M1
Naik, S1
Tredwin, CJ1
Scully, C1
Nyberg, SL1
Remmel, RP1
Mann, HJ1
Peshwa, MV1
Hu, WS1
Cerra, FB1
Pardee, AB1
James, LJ1
Homolka, J1
Mann, AM1
Masui, T1
Chlapowski, FJ1
Okamura, T1
Borgeson, CD1
Cohen, SM1
Wilson, CB1
Hoshino, T1
Veselý, J1
Dvorák, M1
Cihák, A1
Sorm, F1
Thomas, C1
Wessel, W1
Citoler, P1
Sheinin, R1
Onodera, K1
Greenberg, CS1
Glick, MC1
Hung, PP1
Carruthers, C2
Levine, RL1
Hoogenraad, NJ1
Kretchmer, N1
Bhattacharaya, M1
Frei, JV1
Oliver, J1
Warzok, R1
Osske, G1
Zabel-Langhennig, R1
Wilkinson, R1
Pillinger, DJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Imaging for Prostate Cancer Metastasis Detection - Traditional Imaging (Bone Scan and CT) Versus PSMA-PET-CT, SPECT-CT and Whole-Body MRI[NCT03537391]80 participants (Actual)Interventional2018-03-01Completed
Efficacy of Three Antimicrobial Mouthwashes in Reducing SARS-CoV-2 Viral Load in the Saliva of Patients Diagnosed With COVID-19: A Pilot Study[NCT04723446]54 participants (Actual)Interventional2021-05-19Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for urea and Cell Transformation, Neoplastic

ArticleYear
The context-specific roles of urea cycle enzymes in tumorigenesis.
    Molecular cell, 2021, 09-16, Volume: 81, Issue:18

    Topics: Ammonia; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Gene

2021
Hydrogen peroxide tooth-whitening (bleaching): review of safety in relation to possible carcinogenesis.
    Oral oncology, 2006, Volume: 42, Issue:7

    Topics: Animals; Bacteria; Carbamide Peroxide; Cell Transformation, Neoplastic; Disease Models, Animal; Drug

2006
A review: biological and clinical aspects of pyrimidine metabolism.
    Pediatric research, 1974, Volume: 8, Issue:7

    Topics: Ammonia; Animals; Cats; Cell Transformation, Neoplastic; Cytidine; Glucose; Humans; Isoproterenol; L

1974

Other Studies

16 other studies available for urea and Cell Transformation, Neoplastic

ArticleYear
68Ga-complex lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging.
    Bioconjugate chemistry, 2012, Apr-18, Volume: 23, Issue:4

    Topics: Animals; Antigens, Surface; Cell Line, Tumor; Cell Transformation, Neoplastic; Chelating Agents; Ede

2012
Primary hepatocytes outperform Hep G2 cells as the source of biotransformation functions in a bioartificial liver.
    Annals of surgery, 1994, Volume: 220, Issue:1

    Topics: Albumins; Animals; Artificial Organs; Biotransformation; Cell Line, Transformed; Cell Transformation

1994
Selective killing of transformed baby hamster kidney (BHK) cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:12

    Topics: Antibiotics, Antineoplastic; Caffeine; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Cy

1975
[Brdicka's reaction and the effect of denaturants on its result].
    Casopis lekaru ceskych, 1978, Dec-01, Volume: 117, Issue:48

    Topics: Cell Transformation, Neoplastic; Guanidines; Humans; Neoplasms; Urea

1978
In vitro transformation of rat bladder epithelium by 2-amino-4-(5-nitro-2-furyl)thiazole.
    Carcinogenesis, 1991, Volume: 12, Issue:3

    Topics: Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Drug Synergism; Epithelial C

1991
Current trends in the chemotherapy of brain tumors with special reference to glioblastomas.
    Journal of neurosurgery, 1969, Volume: 31, Issue:6

    Topics: Alkaloids; Antibiotics, Antineoplastic; Antineoplastic Agents; Azaguanine; Blood Vessel Prosthesis;

1969
Biochemical mechanisms of drug resistance. XII. Uridine kinases from mouse leukemic cells sensitive and resistant to 5-azacytidine.
    International journal of cancer, 1971, Sep-15, Volume: 8, Issue:2

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Chloromercuribenzoates; Cytidine; Cytosine Nucl

1971
[Histochemical, electronmicroscopical and autoradiographical studies on experimentally induced nephroblastomas].
    Beitrage zur Pathologie, 1972, Volume: 145, Issue:1

    Topics: Angiography; Animals; Autoradiography; Cell Transformation, Neoplastic; Cytoplasm; Female; Kidney Ne

1972
Studies of the plasma membrane of normal and virus-transformed 3 T 3 mouse cells.
    Biochimica et biophysica acta, 1972, Jul-03, Volume: 274, Issue:1

    Topics: Acetates; Adenosine Triphosphatases; Animals; Carbon Isotopes; Cell Line; Cell Membrane; Cell Transf

1972
Electrophoretic study of the polypeptides from surface membranes of mammalian cells.
    Biochemistry, 1972, Sep-26, Volume: 11, Issue:20

    Topics: Animals; Avian Sarcoma Viruses; Butanols; Cell Line; Cell Membrane; Cell Transformation, Neoplastic;

1972
Ribonucleases of Rous sarcoma virus.
    Virology, 1973, Volume: 51, Issue:2

    Topics: Animals; Avian Sarcoma Viruses; Cell Transformation, Neoplastic; Cells, Cultured; Centrifugation, De

1973
Differences in the urea-extracted or fibrous proteins of mouse epidermis at various stages of malignant transformation.
    Oncology, 1974, Volume: 30, Issue:2

    Topics: Adenocarcinoma, Scirrhous; Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Transformatio

1974
Antigenic changes in mouse epidermis at various stages of neoplastic transformation.
    Gan, 1972, Volume: 63, Issue:3

    Topics: Animals; Antigens, Neoplasm; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Epithelium;

1972
Influence of methylnitrosourea on malignant transformation of mouse embryo cells in tissue culture.
    Journal of the National Cancer Institute, 1971, Volume: 47, Issue:4

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Embryo, Mammal

1971
[Studies on the histogenesis of experimentally induced brain tumors. I. Light microscopic findings].
    Experimentelle Pathologie, 1971, Volume: 5, Issue:3

    Topics: Animals; Brain Neoplasms; Cell Transformation, Neoplastic; Cytogenetics; Glioma; Methods; Neoplasm T

1971
Effect of the carcinogen N-nitrosomethylurea on the tRNA methylase activity of cells cultured in vitro.
    International journal of cancer, 1971, Nov-15, Volume: 8, Issue:3

    Topics: Animals; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Cricetinae; Female; F

1971