urea has been researched along with Cataract in 52 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine age-related changes in the composition of the urea-soluble (US) protein fraction from lenses of senescence-accelerated OXYS (cataract model) and Wistar (control) rats and to establish posttranslational modifications (PTMs) occurring under enhanced oxidative stress in OXYS lenses." | 7.79 | Cataract-specific posttranslational modifications and changes in the composition of urea-soluble protein fraction from the rat lens. ( Cherepanov, IV; Sagdeev, RZ; Snytnikova, OA; Tsentalovich, YP; Yanshole, LV; Yanshole, VV, 2013) |
| "Urea-soluble and intrinsic membrane proteins from normal and galactose cataractous rat lenses were analyzed by SDS-PAGE." | 7.68 | Changes of urea-soluble and intrinsic membrane proteins in rat lenses during the formation of galactose cataract. ( Ren, XH; Zhao, HR, 1992) |
| "In an effort to elucidate the molecular changes which take place in the human lens with the onset of nuclear cataract, the urea-insoluble protein fraction, solubilized with dithiothreitol, was digested with trypsin." | 7.68 | Direct approach to identification, at the molecular level, of modified proteins in human nuclear cataractous lenses: beta-crystallin is a component of the urea-insoluble protein fraction. ( O'Hair, RA; Sheil, MM; Truscott, RJ, 1992) |
| "The composition and origin of the urea soluble polypeptides which accumulate in the U18666A rat-cataract were studied." | 7.68 | On the composition and origin of the urea-soluble polypeptides of the U18666A cataract. ( Augusteyn, RC; Cenedella, RJ, 1990) |
| "Nuclear cataract resulting from an overdose of selenite was characterized by a five-fold increase in nuclear urea-soluble protein." | 7.67 | Origin of urea-soluble protein in the selenite cataract. Role of beta-crystallin proteolysis and calpain II. ( David, LL; Dickey, BM; Shearer, TR, 1987) |
| "Several mutations associated with congenital cataracts in human beings target conserved arginine residues in αA-crystallin." | 3.88 | Characterization of an N-terminal mutant of αA-crystallin αA-R21Q associated with congenital cataract. ( Phadte, AS; Santhoshkumar, P; Sharma, KK, 2018) |
| "To determine age-related changes in the composition of the urea-soluble (US) protein fraction from lenses of senescence-accelerated OXYS (cataract model) and Wistar (control) rats and to establish posttranslational modifications (PTMs) occurring under enhanced oxidative stress in OXYS lenses." | 3.79 | Cataract-specific posttranslational modifications and changes in the composition of urea-soluble protein fraction from the rat lens. ( Cherepanov, IV; Sagdeev, RZ; Snytnikova, OA; Tsentalovich, YP; Yanshole, LV; Yanshole, VV, 2013) |
| "The aim of this study was to identify glucocorticoid induced cataracts (GIC)-specific modified water insoluble-urea soluble (WI-US) crystallins and related changes after rat lens were exposed to dexamethasone (Dex)." | 3.77 | Proteomics analysis of water insoluble-urea soluble crystallins from normal and dexamethasone exposed lens. ( Liu, D; Liu, P; Wang, L; Yu, Y, 2011) |
| "The purpose of the study was to compare and analyze the composition of crystallin species that exist in the water insoluble-urea soluble (WI-US) and water insoluble-urea insoluble (WI-UI) protein fractions of a human cataractous lens and an age-matched normal lens." | 3.74 | Proteomic analysis of water insoluble proteins from normal and cataractous human lenses. ( Harrington, V; Kirk, M; Srivastava, OP, 2007) |
| "The objective of this study is to understand the molecular basis of cataract that develops due to the mutation of the glycine-98 residue to arginine in alphaA-crystallin." | 3.73 | The cataract-causing mutation G98R in human alphaA-crystallin leads to folding defects and loss of chaperone activity. ( Ramakrishna, T; Raman, B; Rao, ChM; Singh, D, 2006) |
| "Predominantly nuclear cataract was significantly associated with raised plasma alanine aminotransferase and bilirubin, posterior subcapsular cataract with increased calcium and urea, cuneiform with reduced potassium, mature/hypermature with raised potassium and reduced total carbon dioxide." | 3.69 | Some plasma constituents correlate with human cataract location and nuclear colour. ( Clayton, RM; Cuthbert, J; Donnelly, CA; Phillips, CI; Seth, J, 1997) |
| "Urea-soluble and intrinsic membrane proteins from normal and galactose cataractous rat lenses were analyzed by SDS-PAGE." | 3.68 | Changes of urea-soluble and intrinsic membrane proteins in rat lenses during the formation of galactose cataract. ( Ren, XH; Zhao, HR, 1992) |
| "In an effort to elucidate the molecular changes which take place in the human lens with the onset of nuclear cataract, the urea-insoluble protein fraction, solubilized with dithiothreitol, was digested with trypsin." | 3.68 | Direct approach to identification, at the molecular level, of modified proteins in human nuclear cataractous lenses: beta-crystallin is a component of the urea-insoluble protein fraction. ( O'Hair, RA; Sheil, MM; Truscott, RJ, 1992) |
| "The composition and origin of the urea soluble polypeptides which accumulate in the U18666A rat-cataract were studied." | 3.68 | On the composition and origin of the urea-soluble polypeptides of the U18666A cataract. ( Augusteyn, RC; Cenedella, RJ, 1990) |
| "Nuclear cataract resulting from an overdose of selenite was characterized by a five-fold increase in nuclear urea-soluble protein." | 3.67 | Origin of urea-soluble protein in the selenite cataract. Role of beta-crystallin proteolysis and calpain II. ( David, LL; Dickey, BM; Shearer, TR, 1987) |
| "Cataracts were induced in young Sprague-Dawley rats with a single subcutaneous injection of sodium selenite; age-matched uninjected rats served as controls." | 1.33 | Connexin 46 and connexin 50 in selenite cataract. ( Fleschner, CR, 2006) |
| "Mixed cataract was associated with a history of surgery under general anesthesia (OR = 0." | 1.29 | Risk factors for cortical, nuclear, posterior subcapsular and mixed cataract: a case-control study. ( Balestreri, C; Marighi, PE; Miglior, S; Musicco, M; Nicolosi, A; Orzalesi, N, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (61.54) | 18.7374 |
| 1990's | 11 (21.15) | 18.2507 |
| 2000's | 4 (7.69) | 29.6817 |
| 2010's | 4 (7.69) | 24.3611 |
| 2020's | 1 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Marco-Marín, C | 1 |
| Escamilla-Honrubia, JM | 1 |
| Llácer, JL | 1 |
| Seri, M | 1 |
| Panza, E | 1 |
| Rubio, V | 1 |
| Phadte, AS | 1 |
| Santhoshkumar, P | 1 |
| Sharma, KK | 2 |
| De Simone, E | 1 |
| Di Micco, L | 1 |
| La Manna, G | 1 |
| Di Iorio, B | 1 |
| Yanshole, LV | 1 |
| Cherepanov, IV | 1 |
| Snytnikova, OA | 1 |
| Yanshole, VV | 1 |
| Sagdeev, RZ | 1 |
| Tsentalovich, YP | 1 |
| Wang, L | 1 |
| Liu, D | 1 |
| Liu, P | 1 |
| Yu, Y | 1 |
| KWITKO, ML | 1 |
| FUNAHASHI, T | 1 |
| RAO, SS | 1 |
| MEHTA, PD | 1 |
| COOPER, SN | 1 |
| Fleschner, CR | 1 |
| Singh, D | 1 |
| Raman, B | 1 |
| Ramakrishna, T | 1 |
| Rao, ChM | 1 |
| Harrington, V | 1 |
| Srivastava, OP | 1 |
| Kirk, M | 1 |
| Li, H | 1 |
| Lim, JH | 1 |
| Liu, J | 1 |
| Wong, TY | 1 |
| Crews, SJ | 1 |
| Davidson, SI | 1 |
| Rao, GN | 1 |
| Cotlier, E | 2 |
| Clayton, RM | 3 |
| Cuthbert, J | 3 |
| Duffy, J | 1 |
| Seth, J | 3 |
| Phillips, CI | 3 |
| Bartholomew, RS | 1 |
| Reid, JM | 1 |
| Bloemendal, H | 1 |
| Harding, JJ | 3 |
| Rixon, KC | 1 |
| Mura, CV | 1 |
| Roh, S | 1 |
| Smith, D | 1 |
| Palmer, V | 1 |
| Padhye, N | 1 |
| Taylor, A | 1 |
| Miglior, S | 1 |
| Marighi, PE | 1 |
| Musicco, M | 1 |
| Balestreri, C | 1 |
| Nicolosi, A | 1 |
| Orzalesi, N | 1 |
| Donnelly, CA | 1 |
| Finelli, PF | 1 |
| Roy, D | 1 |
| Spector, A | 1 |
| Maisel, H | 1 |
| Kramps, HA | 1 |
| Hoenders, HJ | 2 |
| Wollensak, J | 2 |
| Zhao, HR | 1 |
| Ren, XH | 1 |
| O'Hair, RA | 1 |
| Sheil, MM | 1 |
| Truscott, RJ | 1 |
| Ortwerth, BJ | 2 |
| Olesen, PR | 2 |
| Abraham, EC | 2 |
| Perry, RE | 1 |
| Abraham, A | 1 |
| Swamy, MS | 2 |
| Obara, Y | 1 |
| Hirano, K | 1 |
| Cenedella, RJ | 1 |
| Augusteyn, RC | 1 |
| France, MP | 1 |
| Shaw, JM | 1 |
| David, LL | 1 |
| Dickey, BM | 1 |
| Shearer, TR | 1 |
| Tabuchi, A | 1 |
| Ikeda, A | 1 |
| Nishikiori, T | 1 |
| Takaba, H | 1 |
| Siezen, RJ | 1 |
| Ringens, PJ | 1 |
| Bistervels, B | 1 |
| Koch, HR | 1 |
| Hockwin, O | 1 |
| White, JH | 1 |
| Cinotti, AA | 1 |
| Babel, J | 1 |
| Leuenberger, P | 1 |
| Cameron, D | 1 |
| Renold, A | 1 |
| Dilley, KJ | 1 |
| Pirie, A | 2 |
| Gaudin, J | 1 |
| Stevens, FC | 1 |
| Murthy, AS | 1 |
| Vawter, GF | 1 |
| Kopito, L | 1 |
| Rossen, E | 1 |
| Auricchio, G | 1 |
| Testa, M | 1 |
| Klein, J | 1 |
| Van Heyningen, R | 1 |
| Zigman, S | 1 |
| Schultz, J | 1 |
| Yulo, T | 1 |
| Gershenovich, ZS | 1 |
| Ul'iankina, TI | 1 |
| Bietti, GB | 1 |
4 reviews available for urea and Cataract
| Article | Year |
|---|---|
Δ
Topics: Aldehyde Dehydrogenase; Bone and Bones; Cataract; Growth Disorders; Humans; Mutation; Pedigree; Phen | 2020 |
[Protein carbamylation: what it is and why it concerns nephrologists].
Topics: Alzheimer Disease; Amino Acids; Amyloidosis; Anemia, Sickle Cell; Animals; Cardiovascular Diseases; | 2018 |
Lens proteins.
Topics: Actins; Amino Acid Sequence; Animals; Cataract; Chromatography; Crystallins; Electrophoresis; Humans | 1982 |
Herpes simplex virus and the human nervous system: current concepts and review.
Topics: Cataract; Chorioretinitis; Dexamethasone; Encephalitis; Encephalitis Viruses; Facial Paralysis; Fema | 1975 |
48 other studies available for urea and Cataract
| Article | Year |
|---|---|
Characterization of an N-terminal mutant of αA-crystallin αA-R21Q associated with congenital cataract.
Topics: alpha-Crystallin A Chain; Animals; Apoptosis; Arginine; Cataract; Cattle; Humans; Lens, Crystalline; | 2018 |
Cataract-specific posttranslational modifications and changes in the composition of urea-soluble protein fraction from the rat lens.
Topics: Acetylation; Amino Acid Sequence; Amino Acids; Animals; Cataract; Chemical Fractionation; Crystallin | 2013 |
Proteomics analysis of water insoluble-urea soluble crystallins from normal and dexamethasone exposed lens.
Topics: Amino Acid Sequence; Animals; Cataract; Crystallins; Dexamethasone; Dose-Response Relationship, Drug | 2011 |
GLAUCOMA DUE TO HYPERMATURE CATARACT: THE USE OF UREA IN DIAGNOSIS.
Topics: Cataract; Cataract Extraction; Diagnosis; Eye Injuries; Geriatrics; Glaucoma; Humans; Injections, In | 1963 |
[CLINICAL USE OF UREA TO THE OPHTHALMIC DISEASES EXCEPTING GLAUCOMA].
Topics: Cataract; Cataract Extraction; Choroid; Corneal Transplantation; Glaucoma; Humans; Retina; Retinal D | 1963 |
ANTIGENIC RELATIONSHIP BETWEEN INSOLUBLE AND SOLUBLE LENS PROTEINS.
Topics: Aging; Alkalies; Animals; Antigens; Biochemical Phenomena; Biochemistry; Cataract; Cattle; Crystalli | 1965 |
Connexin 46 and connexin 50 in selenite cataract.
Topics: Animals; Blotting, Western; Cataract; Connexins; Crystallins; Electrophoresis, Polyacrylamide Gel; E | 2006 |
The cataract-causing mutation G98R in human alphaA-crystallin leads to folding defects and loss of chaperone activity.
Topics: alpha-Crystallin A Chain; Arginine; Cataract; Circular Dichroism; Escherichia coli; Glycine; Humans; | 2006 |
Proteomic analysis of water insoluble proteins from normal and cataractous human lenses.
Topics: Adult; Aged; Cataract; Crystallins; Electrophoresis, Gel, Two-Dimensional; Humans; Lens, Crystalline | 2007 |
Towards automatic grading of nuclear cataract.
Topics: Accommodation, Ocular; Automation; Carbamide Peroxide; Cataract; Drug Combinations; Humans; Image Pr | 2007 |
BIOCHEMICAL OBSERVATIONS DURING INTRAVENOUS UREA THERAPY.
Topics: Acute Disease; Blood Volume; Cataract; Glaucoma; Glaucoma, Angle-Closure; Humans; Infusions, Intrave | 1962 |
Urea cycle enzymes in retina, ciliary body-iris, lens and senile cataracts.
Topics: Aged; Animals; Arginase; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Sy | 1984 |
Some risk factors associated with cataract in S.E. Scotland: a pilot study.
Topics: Aged; Alcohol Drinking; Bacterial Infections; Calcium; Cataract; Cholesterol; Diabetes Complications | 1982 |
Is diarrhoea a major cause of cataract in some tropical countries?
Topics: Acidosis; Animals; Carbamates; Cataract; Cattle; Dehydration; Diarrhea; Eye Proteins; Humans; In Vit | 1981 |
Cataract incidence and analysis of lens crystallins in the water-, urea- and SDS-soluble fractions of Emory mice fed a diet restricted by 40% in calories.
Topics: Aging; Animals; Cataract; Crystallins; Diet; Electrophoresis, Polyacrylamide Gel; Energy Intake; Ene | 1993 |
Risk factors for cortical, nuclear, posterior subcapsular and mixed cataract: a case-control study.
Topics: Adult; Aged; Case-Control Studies; Cataract; Female; Humans; Incidence; Italy; Lens Capsule, Crystal | 1994 |
Some plasma constituents correlate with human cataract location and nuclear colour.
Topics: Aged; Aging; Blood Glucose; Blood Proteins; Calcium; Case-Control Studies; Cataract; Female; Humans; | 1997 |
Human insoluble lens protein. I. Separation and partial characterization of polypeptides.
Topics: Aged; Amino Acids; Cataract; Crystallins; Electrophoresis, Polyacrylamide Gel; Humans; Lens, Crystal | 1978 |
The nature of the urea-isoluble material of the human lens.
Topics: Cataract; Cell Membrane; Crystallins; Humans; Male; Solubility; Urea | 1977 |
Protein changes in the human lens during development of senile nuclear cataract.
Topics: Aged; Cataract; Crystallins; Humans; Isoelectric Focusing; Lens, Crystalline; Middle Aged; Molecular | 1976 |
Changes of urea-soluble and intrinsic membrane proteins in rat lenses during the formation of galactose cataract.
Topics: Animals; Cataract; Crystallins; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Galacto | 1992 |
Direct approach to identification, at the molecular level, of modified proteins in human nuclear cataractous lenses: beta-crystallin is a component of the urea-insoluble protein fraction.
Topics: Amino Acid Sequence; Cataract; Chromatography, High Pressure Liquid; Crystallins; Humans; Lens Nucle | 1992 |
Studies on the solubilization of the water-insoluble fraction from human lens and cataract.
Topics: Amino Acids; Cataract; Chromatography, Gel; Crystallins; Dithiothreitol; Humans; Lens, Crystalline; | 1992 |
The effect of urea on the aggregate state and elastase inhibitor activity of the water-insoluble fraction from bovine and human lens.
Topics: Adult; Amino Acids; Animals; Cataract; Cattle; Crystallins; Electrophoresis, Polyacrylamide Gel; Hum | 1992 |
Proteins of urea-soluble high molecular weight (HMW) aggregates from diabetic cataract: identification of in vivo glycation sites.
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Eye Proteins; Molecular Weight; Solubility; Urea | 1991 |
[The biochemical study in the nucleus opacification of the senile cataractous lens].
Topics: Aged; Cataract; Humans; Lens, Crystalline; Lipoproteins; Solubility; Urea | 1991 |
On the composition and origin of the urea-soluble polypeptides of the U18666A cataract.
Topics: Androstenes; Animals; Aqueous Humor; Cataract; Chromatography, Gel; Crystallins; Electrophoresis, Po | 1990 |
Blood glucose, calcium and urea in cows from a herd with congenital nuclear cataract.
Topics: Animals; Blood Glucose; Calcium; Cataract; Cattle; Cattle Diseases; Female; Pregnancy; Urea | 1990 |
Diuretic drugs as risk factors in cataractogenesis.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cataract; Diuretics; Humans; Middle Aged | 1987 |
Origin of urea-soluble protein in the selenite cataract. Role of beta-crystallin proteolysis and calpain II.
Topics: Animals; Calpain; Cataract; Cell Nucleus; Crystallins; Electrophoresis; Eye Proteins; Immunologic Te | 1987 |
[Water-insoluble fraction of lens proteins in bilateral congenital cataracts].
Topics: Adolescent; Cataract; Child; Child, Preschool; Crystallins; Female; Humans; Infant; Male; Solubility | 1988 |
Reversible osmotic cataracts in spiny dogfish (Squalus acanthias) eye lens.
Topics: Animals; Cataract; Dogfish; Glycerol; Osmolar Concentration; Saline Solution, Hypertonic; Sharks; Ur | 1988 |
Lens protein composition, glycation and high molecular weight aggregation in aging rats.
Topics: Aging; Animals; Cataract; Crystallins; Glycosylation; Male; Molecular Weight; Rats; Rats, Inbred Str | 1987 |
Lens proteins in intumescent cataract.
Topics: Cataract; Chromatography, Gel; Crystallins; Electrophoresis, Polyacrylamide Gel; Humans; Solubility; | 1986 |
[Iatrogenic cataracts].
Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimeth | 1974 |
Streptozotocin-produced cataracts in rats.
Topics: Animals; Anti-Bacterial Agents; Blood Glucose; Cataract; Cell Division; Diabetes Mellitus; Glycosuri | 1972 |
[Experimental diabetic retinopathy in the rat].
Topics: Animals; Basement Membrane; Cataract; Diabetic Retinopathy; Disease Models, Animal; Inclusion Bodies | 1972 |
Changes to the proteins of the human lens nucleus in cataract.
Topics: Aged; Amino Acids; Carbohydrates; Cataract; Crystallins; Humans; Middle Aged; Molecular Weight; Nitr | 1974 |
The trypsin and chymotrypsin inhibitory capacity of human and bovine alpha-crystallin.
Topics: Animals; Binding Sites; Cataract; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chrom | 1974 |
Retinal atrophy and cataract in rats following administration of N-methyl-N-nitrosourea.
Topics: Animals; Atrophy; Calcium; Cataract; Eye; Female; Iron; Lens, Crystalline; Magnesium; Male; Nitroso | 1972 |
Some biochemical differences between cortical (pale) and nuclear (brown) cataracts.
Topics: Age Factors; Cataract; Color; Crystallins; Disulfides; Humans; Lens, Crystalline; Oxidation-Reductio | 1972 |
The nature and origin of the urea-insoluble protein of human lens.
Topics: Cataract; Crystallins; Disulfides; Guanidines; Humans; Nitrogen; Protein Binding; Solubility; Sulfhy | 1972 |
Chemical and mechanical dissolution of human senile cataracts in vitro.
Topics: Adult; Age Factors; Aged; Cataract; Color; Corneal Opacity; Dithiothreitol; Female; Guanidines; Hard | 1972 |
Some changes in the lens of the dimethylsulphoxide-fed rabbit.
Topics: Amino Acids; Animals; Cataract; Chemical Precipitation; Crystallins; Dimethyl Sulfoxide; Disease Mod | 1972 |
Variations in the makeup of lens insoluble proteins.
Topics: Aged; Aging; Animals; Cataract; Cattle; Crystallins; Densitometry; Electrophoresis; Female; Humans; | 1970 |
[Metabolism of free and protein-bound urea in crystalline lenses in normal condition and in cataract].
Topics: Age Factors; Aged; Animals; Cataract; Cattle; Crystallins; Female; Humans; Lens, Crystalline; Male; | 1970 |
[The value of osmotic pressure-decreasing substances in the treatment of increasing intraocular pressure].
Topics: Ascorbic Acid; Cataract; Glaucoma; Glycerol; Humans; Injections, Intravenous; Intraocular Pressure; | 1967 |
Color and solubility of the proteins of human cataracts.
Topics: Animals; Cataract; Cattle; Chemistry Techniques, Analytical; Color; Crystallins; Fluorescence; Human | 1968 |