urea has been researched along with Cataract, Membranous in 52 studies
pseudourea: clinical use; structure
isourea : A carboximidic acid that is the imidic acid tautomer of urea, H2NC(=NH)OH, and its hydrocarbyl derivatives.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine age-related changes in the composition of the urea-soluble (US) protein fraction from lenses of senescence-accelerated OXYS (cataract model) and Wistar (control) rats and to establish posttranslational modifications (PTMs) occurring under enhanced oxidative stress in OXYS lenses." | 7.79 | Cataract-specific posttranslational modifications and changes in the composition of urea-soluble protein fraction from the rat lens. ( Cherepanov, IV; Sagdeev, RZ; Snytnikova, OA; Tsentalovich, YP; Yanshole, LV; Yanshole, VV, 2013) |
| "Urea-soluble and intrinsic membrane proteins from normal and galactose cataractous rat lenses were analyzed by SDS-PAGE." | 7.68 | Changes of urea-soluble and intrinsic membrane proteins in rat lenses during the formation of galactose cataract. ( Ren, XH; Zhao, HR, 1992) |
| "In an effort to elucidate the molecular changes which take place in the human lens with the onset of nuclear cataract, the urea-insoluble protein fraction, solubilized with dithiothreitol, was digested with trypsin." | 7.68 | Direct approach to identification, at the molecular level, of modified proteins in human nuclear cataractous lenses: beta-crystallin is a component of the urea-insoluble protein fraction. ( O'Hair, RA; Sheil, MM; Truscott, RJ, 1992) |
| "The composition and origin of the urea soluble polypeptides which accumulate in the U18666A rat-cataract were studied." | 7.68 | On the composition and origin of the urea-soluble polypeptides of the U18666A cataract. ( Augusteyn, RC; Cenedella, RJ, 1990) |
| "Nuclear cataract resulting from an overdose of selenite was characterized by a five-fold increase in nuclear urea-soluble protein." | 7.67 | Origin of urea-soluble protein in the selenite cataract. Role of beta-crystallin proteolysis and calpain II. ( David, LL; Dickey, BM; Shearer, TR, 1987) |
| "Several mutations associated with congenital cataracts in human beings target conserved arginine residues in αA-crystallin." | 3.88 | Characterization of an N-terminal mutant of αA-crystallin αA-R21Q associated with congenital cataract. ( Phadte, AS; Santhoshkumar, P; Sharma, KK, 2018) |
| "To determine age-related changes in the composition of the urea-soluble (US) protein fraction from lenses of senescence-accelerated OXYS (cataract model) and Wistar (control) rats and to establish posttranslational modifications (PTMs) occurring under enhanced oxidative stress in OXYS lenses." | 3.79 | Cataract-specific posttranslational modifications and changes in the composition of urea-soluble protein fraction from the rat lens. ( Cherepanov, IV; Sagdeev, RZ; Snytnikova, OA; Tsentalovich, YP; Yanshole, LV; Yanshole, VV, 2013) |
| "The aim of this study was to identify glucocorticoid induced cataracts (GIC)-specific modified water insoluble-urea soluble (WI-US) crystallins and related changes after rat lens were exposed to dexamethasone (Dex)." | 3.77 | Proteomics analysis of water insoluble-urea soluble crystallins from normal and dexamethasone exposed lens. ( Liu, D; Liu, P; Wang, L; Yu, Y, 2011) |
| "The purpose of the study was to compare and analyze the composition of crystallin species that exist in the water insoluble-urea soluble (WI-US) and water insoluble-urea insoluble (WI-UI) protein fractions of a human cataractous lens and an age-matched normal lens." | 3.74 | Proteomic analysis of water insoluble proteins from normal and cataractous human lenses. ( Harrington, V; Kirk, M; Srivastava, OP, 2007) |
| "The objective of this study is to understand the molecular basis of cataract that develops due to the mutation of the glycine-98 residue to arginine in alphaA-crystallin." | 3.73 | The cataract-causing mutation G98R in human alphaA-crystallin leads to folding defects and loss of chaperone activity. ( Ramakrishna, T; Raman, B; Rao, ChM; Singh, D, 2006) |
| "Predominantly nuclear cataract was significantly associated with raised plasma alanine aminotransferase and bilirubin, posterior subcapsular cataract with increased calcium and urea, cuneiform with reduced potassium, mature/hypermature with raised potassium and reduced total carbon dioxide." | 3.69 | Some plasma constituents correlate with human cataract location and nuclear colour. ( Clayton, RM; Cuthbert, J; Donnelly, CA; Phillips, CI; Seth, J, 1997) |
| "Urea-soluble and intrinsic membrane proteins from normal and galactose cataractous rat lenses were analyzed by SDS-PAGE." | 3.68 | Changes of urea-soluble and intrinsic membrane proteins in rat lenses during the formation of galactose cataract. ( Ren, XH; Zhao, HR, 1992) |
| "In an effort to elucidate the molecular changes which take place in the human lens with the onset of nuclear cataract, the urea-insoluble protein fraction, solubilized with dithiothreitol, was digested with trypsin." | 3.68 | Direct approach to identification, at the molecular level, of modified proteins in human nuclear cataractous lenses: beta-crystallin is a component of the urea-insoluble protein fraction. ( O'Hair, RA; Sheil, MM; Truscott, RJ, 1992) |
| "The composition and origin of the urea soluble polypeptides which accumulate in the U18666A rat-cataract were studied." | 3.68 | On the composition and origin of the urea-soluble polypeptides of the U18666A cataract. ( Augusteyn, RC; Cenedella, RJ, 1990) |
| "Nuclear cataract resulting from an overdose of selenite was characterized by a five-fold increase in nuclear urea-soluble protein." | 3.67 | Origin of urea-soluble protein in the selenite cataract. Role of beta-crystallin proteolysis and calpain II. ( David, LL; Dickey, BM; Shearer, TR, 1987) |
| "Cataracts were induced in young Sprague-Dawley rats with a single subcutaneous injection of sodium selenite; age-matched uninjected rats served as controls." | 1.33 | Connexin 46 and connexin 50 in selenite cataract. ( Fleschner, CR, 2006) |
| "Mixed cataract was associated with a history of surgery under general anesthesia (OR = 0." | 1.29 | Risk factors for cortical, nuclear, posterior subcapsular and mixed cataract: a case-control study. ( Balestreri, C; Marighi, PE; Miglior, S; Musicco, M; Nicolosi, A; Orzalesi, N, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 32 (61.54) | 18.7374 |
| 1990's | 11 (21.15) | 18.2507 |
| 2000's | 4 (7.69) | 29.6817 |
| 2010's | 4 (7.69) | 24.3611 |
| 2020's | 1 (1.92) | 2.80 |
| Authors | Studies |
|---|---|
| Marco-Marín, C | 1 |
| Escamilla-Honrubia, JM | 1 |
| Llácer, JL | 1 |
| Seri, M | 1 |
| Panza, E | 1 |
| Rubio, V | 1 |
| Phadte, AS | 1 |
| Santhoshkumar, P | 1 |
| Sharma, KK | 2 |
| De Simone, E | 1 |
| Di Micco, L | 1 |
| La Manna, G | 1 |
| Di Iorio, B | 1 |
| Yanshole, LV | 1 |
| Cherepanov, IV | 1 |
| Snytnikova, OA | 1 |
| Yanshole, VV | 1 |
| Sagdeev, RZ | 1 |
| Tsentalovich, YP | 1 |
| Wang, L | 1 |
| Liu, D | 1 |
| Liu, P | 1 |
| Yu, Y | 1 |
| KWITKO, ML | 1 |
| FUNAHASHI, T | 1 |
| RAO, SS | 1 |
| MEHTA, PD | 1 |
| COOPER, SN | 1 |
| Fleschner, CR | 1 |
| Singh, D | 1 |
| Raman, B | 1 |
| Ramakrishna, T | 1 |
| Rao, ChM | 1 |
| Harrington, V | 1 |
| Srivastava, OP | 1 |
| Kirk, M | 1 |
| Li, H | 1 |
| Lim, JH | 1 |
| Liu, J | 1 |
| Wong, TY | 1 |
| Crews, SJ | 1 |
| Davidson, SI | 1 |
| Rao, GN | 1 |
| Cotlier, E | 2 |
| Clayton, RM | 3 |
| Cuthbert, J | 3 |
| Duffy, J | 1 |
| Seth, J | 3 |
| Phillips, CI | 3 |
| Bartholomew, RS | 1 |
| Reid, JM | 1 |
| Bloemendal, H | 1 |
| Harding, JJ | 3 |
| Rixon, KC | 1 |
| Mura, CV | 1 |
| Roh, S | 1 |
| Smith, D | 1 |
| Palmer, V | 1 |
| Padhye, N | 1 |
| Taylor, A | 1 |
| Miglior, S | 1 |
| Marighi, PE | 1 |
| Musicco, M | 1 |
| Balestreri, C | 1 |
| Nicolosi, A | 1 |
| Orzalesi, N | 1 |
| Donnelly, CA | 1 |
| Finelli, PF | 1 |
| Roy, D | 1 |
| Spector, A | 1 |
| Maisel, H | 1 |
| Kramps, HA | 1 |
| Hoenders, HJ | 2 |
| Wollensak, J | 2 |
| Zhao, HR | 1 |
| Ren, XH | 1 |
| O'Hair, RA | 1 |
| Sheil, MM | 1 |
| Truscott, RJ | 1 |
| Ortwerth, BJ | 2 |
| Olesen, PR | 2 |
| Abraham, EC | 2 |
| Perry, RE | 1 |
| Abraham, A | 1 |
| Swamy, MS | 2 |
| Obara, Y | 1 |
| Hirano, K | 1 |
| Cenedella, RJ | 1 |
| Augusteyn, RC | 1 |
| France, MP | 1 |
| Shaw, JM | 1 |
| David, LL | 1 |
| Dickey, BM | 1 |
| Shearer, TR | 1 |
| Tabuchi, A | 1 |
| Ikeda, A | 1 |
| Nishikiori, T | 1 |
| Takaba, H | 1 |
| Siezen, RJ | 1 |
| Ringens, PJ | 1 |
| Bistervels, B | 1 |
| Koch, HR | 1 |
| Hockwin, O | 1 |
| White, JH | 1 |
| Cinotti, AA | 1 |
| Babel, J | 1 |
| Leuenberger, P | 1 |
| Cameron, D | 1 |
| Renold, A | 1 |
| Dilley, KJ | 1 |
| Pirie, A | 2 |
| Gaudin, J | 1 |
| Stevens, FC | 1 |
| Murthy, AS | 1 |
| Vawter, GF | 1 |
| Kopito, L | 1 |
| Rossen, E | 1 |
| Auricchio, G | 1 |
| Testa, M | 1 |
| Klein, J | 1 |
| Van Heyningen, R | 1 |
| Zigman, S | 1 |
| Schultz, J | 1 |
| Yulo, T | 1 |
| Gershenovich, ZS | 1 |
| Ul'iankina, TI | 1 |
| Bietti, GB | 1 |
4 reviews available for urea and Cataract, Membranous
| Article | Year |
|---|---|
Δ
Topics: Aldehyde Dehydrogenase; Bone and Bones; Cataract; Growth Disorders; Humans; Mutation; Pedigree; Phen | 2020 |
[Protein carbamylation: what it is and why it concerns nephrologists].
Topics: Alzheimer Disease; Amino Acids; Amyloidosis; Anemia, Sickle Cell; Animals; Cardiovascular Diseases; | 2018 |
Lens proteins.
Topics: Actins; Amino Acid Sequence; Animals; Cataract; Chromatography; Crystallins; Electrophoresis; Humans | 1982 |
Herpes simplex virus and the human nervous system: current concepts and review.
Topics: Cataract; Chorioretinitis; Dexamethasone; Encephalitis; Encephalitis Viruses; Facial Paralysis; Fema | 1975 |
48 other studies available for urea and Cataract, Membranous
| Article | Year |
|---|---|
Characterization of an N-terminal mutant of αA-crystallin αA-R21Q associated with congenital cataract.
Topics: alpha-Crystallin A Chain; Animals; Apoptosis; Arginine; Cataract; Cattle; Humans; Lens, Crystalline; | 2018 |
Cataract-specific posttranslational modifications and changes in the composition of urea-soluble protein fraction from the rat lens.
Topics: Acetylation; Amino Acid Sequence; Amino Acids; Animals; Cataract; Chemical Fractionation; Crystallin | 2013 |
Proteomics analysis of water insoluble-urea soluble crystallins from normal and dexamethasone exposed lens.
Topics: Amino Acid Sequence; Animals; Cataract; Crystallins; Dexamethasone; Dose-Response Relationship, Drug | 2011 |
GLAUCOMA DUE TO HYPERMATURE CATARACT: THE USE OF UREA IN DIAGNOSIS.
Topics: Cataract; Cataract Extraction; Diagnosis; Eye Injuries; Geriatrics; Glaucoma; Humans; Injections, In | 1963 |
[CLINICAL USE OF UREA TO THE OPHTHALMIC DISEASES EXCEPTING GLAUCOMA].
Topics: Cataract; Cataract Extraction; Choroid; Corneal Transplantation; Glaucoma; Humans; Retina; Retinal D | 1963 |
ANTIGENIC RELATIONSHIP BETWEEN INSOLUBLE AND SOLUBLE LENS PROTEINS.
Topics: Aging; Alkalies; Animals; Antigens; Biochemical Phenomena; Biochemistry; Cataract; Cattle; Crystalli | 1965 |
Connexin 46 and connexin 50 in selenite cataract.
Topics: Animals; Blotting, Western; Cataract; Connexins; Crystallins; Electrophoresis, Polyacrylamide Gel; E | 2006 |
The cataract-causing mutation G98R in human alphaA-crystallin leads to folding defects and loss of chaperone activity.
Topics: alpha-Crystallin A Chain; Arginine; Cataract; Circular Dichroism; Escherichia coli; Glycine; Humans; | 2006 |
Proteomic analysis of water insoluble proteins from normal and cataractous human lenses.
Topics: Adult; Aged; Cataract; Crystallins; Electrophoresis, Gel, Two-Dimensional; Humans; Lens, Crystalline | 2007 |
Towards automatic grading of nuclear cataract.
Topics: Accommodation, Ocular; Automation; Carbamide Peroxide; Cataract; Drug Combinations; Humans; Image Pr | 2007 |
BIOCHEMICAL OBSERVATIONS DURING INTRAVENOUS UREA THERAPY.
Topics: Acute Disease; Blood Volume; Cataract; Glaucoma; Glaucoma, Angle-Closure; Humans; Infusions, Intrave | 1962 |
Urea cycle enzymes in retina, ciliary body-iris, lens and senile cataracts.
Topics: Aged; Animals; Arginase; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Sy | 1984 |
Some risk factors associated with cataract in S.E. Scotland: a pilot study.
Topics: Aged; Alcohol Drinking; Bacterial Infections; Calcium; Cataract; Cholesterol; Diabetes Complications | 1982 |
Is diarrhoea a major cause of cataract in some tropical countries?
Topics: Acidosis; Animals; Carbamates; Cataract; Cattle; Dehydration; Diarrhea; Eye Proteins; Humans; In Vit | 1981 |
Cataract incidence and analysis of lens crystallins in the water-, urea- and SDS-soluble fractions of Emory mice fed a diet restricted by 40% in calories.
Topics: Aging; Animals; Cataract; Crystallins; Diet; Electrophoresis, Polyacrylamide Gel; Energy Intake; Ene | 1993 |
Risk factors for cortical, nuclear, posterior subcapsular and mixed cataract: a case-control study.
Topics: Adult; Aged; Case-Control Studies; Cataract; Female; Humans; Incidence; Italy; Lens Capsule, Crystal | 1994 |
Some plasma constituents correlate with human cataract location and nuclear colour.
Topics: Aged; Aging; Blood Glucose; Blood Proteins; Calcium; Case-Control Studies; Cataract; Female; Humans; | 1997 |
Human insoluble lens protein. I. Separation and partial characterization of polypeptides.
Topics: Aged; Amino Acids; Cataract; Crystallins; Electrophoresis, Polyacrylamide Gel; Humans; Lens, Crystal | 1978 |
The nature of the urea-isoluble material of the human lens.
Topics: Cataract; Cell Membrane; Crystallins; Humans; Male; Solubility; Urea | 1977 |
Protein changes in the human lens during development of senile nuclear cataract.
Topics: Aged; Cataract; Crystallins; Humans; Isoelectric Focusing; Lens, Crystalline; Middle Aged; Molecular | 1976 |
Changes of urea-soluble and intrinsic membrane proteins in rat lenses during the formation of galactose cataract.
Topics: Animals; Cataract; Crystallins; Disease Models, Animal; Electrophoresis, Polyacrylamide Gel; Galacto | 1992 |
Direct approach to identification, at the molecular level, of modified proteins in human nuclear cataractous lenses: beta-crystallin is a component of the urea-insoluble protein fraction.
Topics: Amino Acid Sequence; Cataract; Chromatography, High Pressure Liquid; Crystallins; Humans; Lens Nucle | 1992 |
Studies on the solubilization of the water-insoluble fraction from human lens and cataract.
Topics: Amino Acids; Cataract; Chromatography, Gel; Crystallins; Dithiothreitol; Humans; Lens, Crystalline; | 1992 |
The effect of urea on the aggregate state and elastase inhibitor activity of the water-insoluble fraction from bovine and human lens.
Topics: Adult; Amino Acids; Animals; Cataract; Cattle; Crystallins; Electrophoresis, Polyacrylamide Gel; Hum | 1992 |
Proteins of urea-soluble high molecular weight (HMW) aggregates from diabetic cataract: identification of in vivo glycation sites.
Topics: Animals; Cataract; Diabetes Mellitus, Experimental; Eye Proteins; Molecular Weight; Solubility; Urea | 1991 |
[The biochemical study in the nucleus opacification of the senile cataractous lens].
Topics: Aged; Cataract; Humans; Lens, Crystalline; Lipoproteins; Solubility; Urea | 1991 |
On the composition and origin of the urea-soluble polypeptides of the U18666A cataract.
Topics: Androstenes; Animals; Aqueous Humor; Cataract; Chromatography, Gel; Crystallins; Electrophoresis, Po | 1990 |
Blood glucose, calcium and urea in cows from a herd with congenital nuclear cataract.
Topics: Animals; Blood Glucose; Calcium; Cataract; Cattle; Cattle Diseases; Female; Pregnancy; Urea | 1990 |
Diuretic drugs as risk factors in cataractogenesis.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cataract; Diuretics; Humans; Middle Aged | 1987 |
Origin of urea-soluble protein in the selenite cataract. Role of beta-crystallin proteolysis and calpain II.
Topics: Animals; Calpain; Cataract; Cell Nucleus; Crystallins; Electrophoresis; Eye Proteins; Immunologic Te | 1987 |
[Water-insoluble fraction of lens proteins in bilateral congenital cataracts].
Topics: Adolescent; Cataract; Child; Child, Preschool; Crystallins; Female; Humans; Infant; Male; Solubility | 1988 |
Reversible osmotic cataracts in spiny dogfish (Squalus acanthias) eye lens.
Topics: Animals; Cataract; Dogfish; Glycerol; Osmolar Concentration; Saline Solution, Hypertonic; Sharks; Ur | 1988 |
Lens protein composition, glycation and high molecular weight aggregation in aging rats.
Topics: Aging; Animals; Cataract; Crystallins; Glycosylation; Male; Molecular Weight; Rats; Rats, Inbred Str | 1987 |
Lens proteins in intumescent cataract.
Topics: Cataract; Chromatography, Gel; Crystallins; Electrophoresis, Polyacrylamide Gel; Humans; Solubility; | 1986 |
[Iatrogenic cataracts].
Topics: Aged; Anesthetics, Local; Anthelmintics; Azathioprine; Cataract; Chloroquine; Chlorpromazine; Dimeth | 1974 |
Streptozotocin-produced cataracts in rats.
Topics: Animals; Anti-Bacterial Agents; Blood Glucose; Cataract; Cell Division; Diabetes Mellitus; Glycosuri | 1972 |
[Experimental diabetic retinopathy in the rat].
Topics: Animals; Basement Membrane; Cataract; Diabetic Retinopathy; Disease Models, Animal; Inclusion Bodies | 1972 |
Changes to the proteins of the human lens nucleus in cataract.
Topics: Aged; Amino Acids; Carbohydrates; Cataract; Crystallins; Humans; Middle Aged; Molecular Weight; Nitr | 1974 |
The trypsin and chymotrypsin inhibitory capacity of human and bovine alpha-crystallin.
Topics: Animals; Binding Sites; Cataract; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chrom | 1974 |
Retinal atrophy and cataract in rats following administration of N-methyl-N-nitrosourea.
Topics: Animals; Atrophy; Calcium; Cataract; Eye; Female; Iron; Lens, Crystalline; Magnesium; Male; Nitroso | 1972 |
Some biochemical differences between cortical (pale) and nuclear (brown) cataracts.
Topics: Age Factors; Cataract; Color; Crystallins; Disulfides; Humans; Lens, Crystalline; Oxidation-Reductio | 1972 |
The nature and origin of the urea-insoluble protein of human lens.
Topics: Cataract; Crystallins; Disulfides; Guanidines; Humans; Nitrogen; Protein Binding; Solubility; Sulfhy | 1972 |
Chemical and mechanical dissolution of human senile cataracts in vitro.
Topics: Adult; Age Factors; Aged; Cataract; Color; Corneal Opacity; Dithiothreitol; Female; Guanidines; Hard | 1972 |
Some changes in the lens of the dimethylsulphoxide-fed rabbit.
Topics: Amino Acids; Animals; Cataract; Chemical Precipitation; Crystallins; Dimethyl Sulfoxide; Disease Mod | 1972 |
Variations in the makeup of lens insoluble proteins.
Topics: Aged; Aging; Animals; Cataract; Cattle; Crystallins; Densitometry; Electrophoresis; Female; Humans; | 1970 |
[Metabolism of free and protein-bound urea in crystalline lenses in normal condition and in cataract].
Topics: Age Factors; Aged; Animals; Cataract; Cattle; Crystallins; Female; Humans; Lens, Crystalline; Male; | 1970 |
[The value of osmotic pressure-decreasing substances in the treatment of increasing intraocular pressure].
Topics: Ascorbic Acid; Cataract; Glaucoma; Glycerol; Humans; Injections, Intravenous; Intraocular Pressure; | 1967 |
Color and solubility of the proteins of human cataracts.
Topics: Animals; Cataract; Cattle; Chemistry Techniques, Analytical; Color; Crystallins; Fluorescence; Human | 1968 |